Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Rheumatoid arthritis 💬
 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
2 Rheumatoid arthritis 💬
 [2] CD80, CD86 💬 Abatacept 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬
3 Rheumatoid arthritis 💬
 [2] CD80, CD86 💬 Belatacept 💬 Belatacept [1] 46 💬 💬
4 Rheumatoid arthritis 💬
 [1] CSF2 💬 Otilimab 💬 Otilimab [1] 46 💬 💬
5 Rheumatoid arthritis 💬
 [1] CTLA4 💬 Ipilimumab 💬 Ipilimumab [1] 159 💬 💬
6 Rheumatoid arthritis 💬
 [1] CTLA4 💬 Tremelimumab 💬 Tremelimumab [1] 96 💬 💬
7 Rheumatoid arthritis 💬
 [1] FLT1 💬 Axitinib 💬 Axitinib [1] 34 💬 💬
8 Rheumatoid arthritis 💬
 [1] FLT1 💬 Cediranib 💬 Cediranib [1] 34 💬 💬
9 Rheumatoid arthritis 💬
 [1] FLT1 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬 💬
10 Rheumatoid arthritis 💬
 [1] FLT1 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬 💬
11 Rheumatoid arthritis 💬
 [1] IFNG 💬 Emapalumab 💬 Emapalumab [3] 49, 65, 107 💬 💬
12 Rheumatoid arthritis 💬
 [1] IFNG 💬 Fontolizumab 💬 Fontolizumab [1] 46 💬 💬
13 Rheumatoid arthritis 💬
 [1] IL17A 💬 Bimekizumab 💬 Bimekizumab [3] 46, 97, 271 💬 💬
14 Rheumatoid arthritis 💬
 [1] IL17A 💬 Ixekizumab 💬 Ixekizumab [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 💬
15 Rheumatoid arthritis 💬
 [1] IL17A 💬 Secukinumab 💬 Secukinumab [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 💬
16 Rheumatoid arthritis 💬
 [2] IL17A, TNFSF13B 💬 Tibulizumab 💬 Tibulizumab [1] 53 💬 💬
17 Rheumatoid arthritis 💬
 [1] IL1A 💬 Bermekimab 💬 Bermekimab [1] 51 💬 💬
18 Rheumatoid arthritis 💬
 [2] IL1A, IL1B 💬 Rilonacept 💬 Rilonacept [4] 51, 106, 107, 266 💬 💬
19 Rheumatoid arthritis 💬
 [1] IL1B 💬 Canakinumab 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
20 Rheumatoid arthritis 💬
 [1] IL1B 💬 Gevokizumab 💬 Gevokizumab [4] 41, 50, 56, 269 💬 💬
21 Rheumatoid arthritis 💬
 [1] IL23A 💬 Brazikumab 💬 Brazikumab [2] 96, 97 💬 💬
22 Rheumatoid arthritis 💬
 [1] IL23A 💬 Guselkumab 💬 Guselkumab [5] 37, 41, 51, 96, 97 💬 💬
23 Rheumatoid arthritis 💬
 [1] IL23A 💬 Mirikizumab 💬 Mirikizumab [3] 37, 96, 97 💬 💬
24 Rheumatoid arthritis 💬
 [1] IL23A 💬 Risankizumab 💬 Risankizumab [4] 37, 96, 97, 271 💬 💬
25 Rheumatoid arthritis 💬
 [1] IL23A 💬 Tildrakizumab 💬 Tildrakizumab [2] 162, 271 💬 💬
26 Rheumatoid arthritis 💬
 [1] IL23A 💬 Ustekinumab 💬 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬
27 Rheumatoid arthritis 💬
 [1] IL6 💬 Olokizumab 💬 Olokizumab [2] 46, 96 💬 💬
28 Rheumatoid arthritis 💬
 [1] IL6 💬 Siltuximab 💬 Siltuximab [2] 28, 331 💬 💬
29 Rheumatoid arthritis 💬
 [1] IL6 💬 Sirukumab 💬 Sirukumab [2] 41, 46 💬 💬
30 Rheumatoid arthritis 💬
 [2] IL6, TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬 💬
31 Rheumatoid arthritis 💬
 [1] ITGAL 💬 Efalizumab 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬
32 Rheumatoid arthritis 💬
 [1] LTB 💬 Baminercept 💬 Baminercept [4] 13, 46, 53, 97 💬 💬
33 Rheumatoid arthritis 💬
 [3] TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab [3] 51, 85, 222 💬 💬
34 Rheumatoid arthritis 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
35 Rheumatoid arthritis 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
36 Rheumatoid arthritis 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
37 Rheumatoid arthritis 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
38 Rheumatoid arthritis 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
39 Rheumatoid arthritis 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
40 Rheumatoid arthritis 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬 💬
41 Rheumatoid arthritis 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬 💬
42 Rheumatoid arthritis 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬
43 Rheumatoid arthritis 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬 💬
44 Rheumatoid arthritis 💬
 [2] TNFSF13, TNFSF13B 💬 Atacicept 💬 Atacicept [4] 13, 46, 49, 66 💬 💬
45 Rheumatoid arthritis 💬
 [1] TNFSF13B 💬 Belimumab 💬 Belimumab [13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬 💬
46 Rheumatoid arthritis 💬
 [1] TNFSF13B 💬 Tabalumab 💬 Tabalumab [2] 46, 49 💬 💬
47 Rheumatoid arthritis 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬 💬
48 Rheumatoid arthritis 💬
 [1] VEGFA 💬 Bevacizumab 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬 💬
49 Rheumatoid arthritis 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬 💬