17. Multiple system atrophy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 119 / Drugs : 138 - (DrugBank : 44) / Drug target genes : 59 - Drug target pathways : 111
Multiple system atrophy and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability
ID | Diseases (Sorted by drug repositionability) |
---|---|
17 | Multiple system atrophy |
6 | Parkinson disease |
2 | Amyotrophic lateral sclerosis |
5 | Progressive supranuclear palsy |
13 | Multiple sclerosis/Neuromyelitis optica |
206 | Fragile X syndrome |
8 | Huntington disease |
46 | Malignant rheumatoid arthritis |
18 | Spinocerebellar degeneration |
97 | Ulcerative colitis |
140 | Dorabe syndrome |
156 | Rett syndrome |
3 | Spinal muscular atrophy |
96 | Crohn disease |
70 | Spinal stenosis |
22 | Moyamoya disease |
193 | Prader-Willi syndrome |
201 | Angelman syndrome |
21 | Mitochondrial disease |
144 | Lennox-Gastaut syndrome |
205 | Fragile X syndrome related disease |
152 | PCDH19 related syndrome |
296 | Biliary atresia |
158 | Tuberous sclerosis |
203 | 22q11.2 deletion syndrome |
98 | Eosinophilic gastrointestinal disease |
145 | West syndrome |
36 | Epidermolysis bullosa |
272 | Fibrodysplasia ossificans progressiva |
4 | Primary lateral sclerosis |
75 | Cushing disease |
155 | Acquired aphasia with convulsive disorder |
231 | Alpha-1-antitrypsin deficiency |
34 | Neurofibromatosis |
215 | Tetralogy of Fallot |
113 | Muscular dystrophy |
84 | Sarcoidosis |
169 | Menkes disease |
170 | Occipital horn syndrome |
127 | Frontotemporal lobar degeneration |
298 | Hereditary pancreatitis |
118 | Myelomeningocele |
86 | Pulmonary arterial hypertension |
57 | Idiopathic dilated cardiomyopathy |
85 | Idiopathic interstitial pneumonia |
78 | Hypopituitarism |
7 | Corticobasal degeneration |
280 | Huge arteriovenous malformation with cervicofacial or limb lesion |
299 | Cystic fibrosis |
11 | Myasthenia gravis |
49 | Systemic lupus erythematosus |
278 | Huge lymphatic malformation with cervicofacial lesion |
288 | Autoimmune acquired coagulation factor deficiency |
323 | Aromatic L-amino acid decarboxylase deficiency |
90 | Retinitis pigmentosa |
167 | Marfan syndrome |
67 | Polycystic kidney disease |
226 | Interstitial cystitis with Hunners ulcer |
309 | Progressive myoclonus epilepsy |
58 | Hypertrophic cardiomyopathy |
210 | Single Ventricle |
164 | Oculocutaneous albinism |
66 | IgA nephropathy |
120 | Hereditary dystonia |
179 | Williams syndrome |
157 | Sturge-Weber syndrome |
74 | Prolactin secreting pituitary adenoma |
254 | Porphyria |
218 | Alport syndrome |
19 | Lysosomal storage disease |
212 | Tricuspid atresia |
222 | Primary nephrotic syndrome |
137 | Focal cortical dysplasia |
192 | Cockayne syndrome |
277 | Lymphangiomatosis |
281 | Klippel-Trenaunay-Weber syndrome |
111 | Congenital myopathy |
52 | Mixed connective tissue disease |