Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Ampreloxetine [1] Ampreloxetine[1] Ampreloxetine 💬[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 17 💬
2 Angiotensin II [2] Angiotensin; Angiotensin II[2] Angiotensin II ,
Angiotensin II 💬		[2] AGTR1,
AGTR2 💬		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224 💬
3 Atomoxetine [2] Atomoxetine; Strattera[1] Atomoxetine 💬[1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17 💬
4 Botulinum toxin type A [8] BOTOX; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin[1] Botulinum toxin type A 💬[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
5 BQ-123 [0] ---[1] 17 💬
6 Captopril [1] Captopril[1] Captopril 💬[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[8] 6, 17, 46, 86, 96, 97, 107, 271 💬
7 Carbidopa [8] CARBIDOPA; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] Carbidopa 💬[1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
8 Carbonate ion [1] Carbonate---[12] 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299 💬
9 Domperidone [1] Domperidone[2] Domperidone ,
Domperidone maleate 💬		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
10 Droxidopa [4] DOPS; Droxidopa; L-DOPS; Northera[1] Droxidopa 💬[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
11 Emeramide [1] Emeramide---[2] 5, 17 💬
12 Entacapone [5] COMTAN; Comtess; ENTACAPONA; ENTACAPONE; Stalevo[1] Entacapone 💬[1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17 💬
13 Epigallocatechin gallate [3] EGCG; Epigallocatechin gallate; Epigallocatechin-3-gallate---[9] 6, 8, 13, 17, 28, 85, 113, 206, 299 💬
14 Exenatide [3] Bydureon; Byetta; Exenatide[1] Exenatide 💬[1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233 💬
15 Fipamezole [1] Fipamezole---[2] 6, 17 💬
16 Fludrocortisone [1] Fludrocortisone[1] Fludrocortisone 💬[1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81 💬
17 Flumazenil [1] Flumazenil[1] Flumazenil 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
18 Fluoxetine [5] Fluoxetin; FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[1] Fluoxetine 💬[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206 💬
19 Gold [1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
20 Green tea leaf [4] Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract[1] Green tea leaf 💬--[4] 6, 17, 28, 46 💬
21 Human immunoglobulin G [19] Bivigam; CUTAQUIG; CUVITRU; GAMMAGARD LIQUID; Gammaplex; GAMUNEX-C; Hizentra; Human immunoglobulin G; HUMAN NORMAL IMMUNOGLOBULIN; HYQVIA; Immune globulin; Immunoglobulin; IMMUNOGLOBULIN G; IVIg; KIOVIG; OCTAGAM; PANZYGA; Privigen; Vivaglobin---[10] 11, 13, 14, 17, 43, 45, 50, 51, 63, 65 💬
22 Hydrogen [2] Dihydrogen; Hydrogen---[7] 5, 6, 17, 65, 83, 97, 226 💬
23 Inosine [1] Inosine[1] Inosine 💬--[6] 2, 6, 13, 17, 85, 122 💬
24 Levodopa [9] Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] Levodopa 💬[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[6] 6, 17, 90, 140, 164, 201 💬
25 Lithium carbonate [2] Lithium; Lithium Carbonate[1] Lithium carbonate 💬--[5] 2, 13, 17, 18, 127 💬
26 Losartan [3] Cozaar; Losartan; LOSARTAN POTASSIUM[1] Losartan 💬[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
27 Metoprolol [2] Metoprolol; METOPROLOL SUCCINATE[1] Metoprolol 💬[1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
28 Midodrine [2] Midodrine; MIDODRINE HYDROCHLORIDE[1] Midodrine 💬[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 6, 17, 58 💬
29 Nebivolol [1] Nebivolol[1] Nebivolol 💬[1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 17, 85, 113, 167 💬
30 Nitrogen [1] Nitrogen[1] Nitrogen 💬--[5] 5, 6, 17, 211, 299 💬
31 Pseudoephedrine [1] Pseudoephedrine[1] Pseudoephedrine 💬[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17 💬
32 Raclopride [1] Raclopride---[4] 5, 6, 7, 17 💬
33 Rasagiline [4] AZILECT; Rasagilina; Rasagiline; Rasagiline mesylate[2] Rasagiline ,
Rasagiline tartrate 💬		[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[6] 2, 5, 6, 17, 58, 66 💬
34 Rifampicin [2] Rifampicin; Rifampin[1] Rifampin 💬--[9] 6, 13, 17, 46, 84, 86, 93, 299, 338 💬
35 Riluzole [2] Rilutek; Riluzole[1] Riluzole 💬[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
36 Safinamide [3] Safinamida; SAFINAMIDE; Xadago[1] Safinamide 💬[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17 💬
37 Sirolimus [3] RAPAMUNE; Rapamycin; Sirolimus[1] Sirolimus 💬[1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
38 Tea leaf [1] Tea leaf---[2] 17, 46 💬
39 Tolterodine [1] Tolterodine[1] Tolterodine 💬[1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 17, 53 💬
40 Trimethaphan [1] Trimethaphan---[1] 17 💬
41 Ubiquinol [1] Ubiquinol---[3] 6, 8, 17 💬
42 Verdiperstat [1] Verdiperstat[1] Verdiperstat 💬[1] MPO 💬[5] Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬[3] 2, 17, 127 💬
43 Water [8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION[1] Water 💬--[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
44 Zoledronic acid [4] ACLASTA; Zoledronate; ZOLEDRONIC ACID; Zometa[2] Zoledronic acid ,
Zoledronic acid 💬		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬