Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tolterodine 💬 Tolterodine [2] 17, 53 💬
2 COMT 💬 [4] Steroid hormone biosynthesis, Tyrosine metabolism, Metabolic pathways, Dopaminergic synapse Entacapone 💬 Entacapone [2] 6, 17 💬
3 ADRA1D 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
4 ADRA1D 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Midodrine 💬 Midodrine [3] 6, 17, 58 💬
5 ADRA1D 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
6 ADRA1B 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
7 ADRA1B 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Midodrine 💬 Midodrine [3] 6, 17, 58 💬
8 ADRA1B 💬 [6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
9 ADRA1A 💬 [7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
10 ADRA1A 💬 [7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Midodrine 💬 Midodrine [3] 6, 17, 58 💬
11 ADRA1A 💬 [7] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
12 ADRA2A 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
13 ADRA2A 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
14 ADRA2B 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
15 ADRA2B 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
16 ADRA2C 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
17 ADRA2C 💬 [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
18 ADRB1 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
19 ADRB1 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Metoprolol 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
20 ADRB1 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Nebivolol 💬 Nebivolol [4] 17, 85, 113, 167 💬
21 ADRB1 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
22 ADRB2 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
23 ADRB2 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
24 ADRB3 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Droxidopa 💬 Droxidopa [5] 5, 6, 17, 169, 170 💬
25 ADRB3 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Pseudoephedrine 💬 Pseudoephedrine [1] 17 💬
26 ACE 💬 [6] Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hypertrophic cardiomyopathy, Diabetic cardiomyopathy Captopril 💬 Captopril [8] 6, 17, 46, 86, 96, 97, 107, 271 💬
27 DDC 💬 [9] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Carbidopa 💬 Carbidopa [7] 6, 13, 17, 90, 140, 164, 201 💬
28 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
29 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
30 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Domperidone 💬 Domperidone [5] 6, 13, 17, 51, 230 💬
31 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Domperidone maleate 💬 Domperidone [5] 6, 13, 17, 51, 230 💬
32 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
33 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
34 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
35 AGTR1 💬 [16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease - COVID-19, Pathways in cancer, Diabetic cardiomyopathy Angiotensin II 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
36 AGTR1 💬 [16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease - COVID-19, Pathways in cancer, Diabetic cardiomyopathy Angiotensin II 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
37 AGTR1 💬 [16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease - COVID-19, Pathways in cancer, Diabetic cardiomyopathy Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
38 AGTR2 💬 [3] Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Renin-angiotensin system Angiotensin II 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
39 AGTR2 💬 [3] Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Renin-angiotensin system Angiotensin II 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
40 FDPS 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid [13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
41 FDPS 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid [13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
42 MTOR 💬 [51] EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 signaling pathway, Phospholipase D signaling pathway, Autophagy - other, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Apelin signaling pathway, Neutrophil extracellular trap formation, JAK-STAT signaling pathway, Th17 cell differentiation, Thermogenesis, Insulin signaling pathway, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Growth hormone synthesis, secretion and action, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Glioma, Prostate cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy Sirolimus 💬 Sirolimus [40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
43 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
44 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
45 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
46 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
47 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
48 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
49 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
50 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
51 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
52 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
53 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
54 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
55 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
56 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
57 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
58 GLP1R 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Insulin secretion Exenatide 💬 Exenatide [6] 6, 17, 72, 78, 193, 233 💬
59 GRIA1 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
60 GRIA2 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
61 GRIA3 💬 [13] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
62 GRIA4 💬 [10] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
63 GRIK1 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
64 GRIK2 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
65 GRIK3 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
66 GRIK4 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
67 GRIK5 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
68 GRIN1 💬 [18] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
69 GRIN2A 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
70 GRIN2B 💬 [19] Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
71 GRIN2C 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
72 GRIN2D 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
73 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline 💬 Rasagiline [6] 2, 5, 6, 17, 58, 66 💬
74 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Safinamide 💬 Safinamide [2] 6, 17 💬
75 MAOB 💬 [14] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline tartrate 💬 Rasagiline [6] 2, 5, 6, 17, 58, 66 💬
76 NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption Fludrocortisone 💬 Fludrocortisone [3] 6, 17, 81 💬
77 MPO 💬 [5] Drug metabolism - other enzymes, Phagosome, Neutrophil extracellular trap formation, Transcriptional misregulation in cancer, Acute myeloid leukemia Verdiperstat 💬 Verdiperstat [3] 2, 17, 127 💬
78 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
79 SLC6A2 💬 [1] Synaptic vesicle cycle Atomoxetine 💬 Atomoxetine [4] 6, 8, 13, 17 💬
80 SLC6A2 💬 [1] Synaptic vesicle cycle Ampreloxetine 💬 Ampreloxetine [2] 6, 17 💬
81 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Fluoxetine 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬
82 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Ampreloxetine 💬 Ampreloxetine [2] 6, 17 💬
83 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A [14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬