DR info

Clinical trials : 645 / Drugs : 589 - (DrugBank : 163) / Drug target genes : 150 - Drug target pathways : 225

Amyotrophic lateral sclerosis and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
2	Amyotrophic lateral sclerosis
13	Multiple sclerosis/Neuromyelitis optica
6	Parkinson disease
96	Crohn disease
46	Malignant rheumatoid arthritis
156	Rett syndrome
8	Huntington disease
5	Progressive supranuclear palsy
97	Ulcerative colitis
206	Fragile X syndrome
17	Multiple system atrophy
3	Spinal muscular atrophy
140	Dorabe syndrome
21	Mitochondrial disease
144	Lennox-Gastaut syndrome
65	Primary immunodeficiency
34	Neurofibromatosis
70	Spinal stenosis
18	Spinocerebellar degeneration
85	Idiopathic interstitial pneumonia
193	Prader-Willi syndrome
226	Interstitial cystitis with Hunners ulcer
36	Epidermolysis bullosa
49	Systemic lupus erythematosus
299	Cystic fibrosis
113	Muscular dystrophy
158	Tuberous sclerosis
26	HTLV-1-associated myelopathy
51	Scleroderma
86	Pulmonary arterial hypertension
145	West syndrome
98	Eosinophilic gastrointestinal disease
22	Moyamoya disease
201	Angelman syndrome
205	Fragile X syndrome related disease
127	Frontotemporal lobar degeneration
28	Systemic amyloidosis
231	Alpha-1-antitrypsin deficiency
84	Sarcoidosis
78	Hypopituitarism
298	Hereditary pancreatitis
107	Juvenile idiopathic arthritis
56	Behcet disease
152	PCDH19 related syndrome
42	Polyarteritis nodosa
296	Biliary atresia
331	Idiopathic multicentric castleman disease
90	Retinitis pigmentosa
63	Idiopathic thrombocytopenic purpura
75	Cushing disease
203	22q11.2 deletion syndrome
53	Sjogren syndrome
222	Primary nephrotic syndrome
272	Fibrodysplasia ossificans progressiva
4	Primary lateral sclerosis
38	Stevens-Johnson syndrome
62	Paroxysmal nocturnal hemoglobinuria
58	Hypertrophic cardiomyopathy
254	Porphyria
265	Lipodystrophy
266	Familial mediterranean fever
11	Myasthenia gravis
149	Hemiconvulsion hemiplegia epilepsy syndrome
93	Primary biliary cholangitis
256	Muscle glycogenosis
1	Spinal and bulbar muscular atrophy
283	Acquired pure red cell aplasia
155	Acquired aphasia with convulsive disorder
50	Dermatomyositis
210	Single Ventricle
162	Pemphigoid
164	Oculocutaneous albinism
215	Tetralogy of Fallot
285	Fanconi anemia
66	IgA nephropathy
35	Pemphigus
95	Autoimmune hepatitis
89	Lymphangioleiomyomatosis
39	Toxic epidermal necrolysis
233	Wolfram syndrome
19	Lysosomal storage disease
280	Huge arteriovenous malformation with cervicofacial or limb lesion
61	Autoimmune hemolytic anemia
7	Corticobasal degeneration
60	Aplastic anemia
102	Rubinstein-Taybi syndrome
284	Diamond-Blackfan anemia
20	Adrenoleukodystrophy
224	Purpura nephritis
236	Pseudohypoparathyroidism
118	Myelomeningocele
151	Rasmussen encephalitis
45	Eosinophilic granulomatosis with Polyangiitis
228	Bronchiolitis obliterans
169	Menkes disease
170	Occipital horn syndrome
74	Prolactin secreting pituitary adenoma
302	Leber hereditary optic neuropathy
294	Congenital diaphragmatic hernia
10	Charcot-Marie-Tooth disease
269	Pyogenic arthritis
55	Relapsing polychondritis
234	Peroxisomal disease (except Adrenoleukodystrophy)
83	Addison disease
76	Pituitary gonadotropin secretion hyperthyroidism
64	Thrombotic thrombocytopenic purpura
41	Giant cell arteritis
271	Ankylosing spondylitis
168	Ehlers-Danlos syndrome
57	Idiopathic dilated cardiomyopathy
309	Progressive myoclonus epilepsy
246	Methylmalonic acidemia
227	Osler disease
160	Congenital ichthyosis
94	Primary sclerosing cholangitis
40	Takayasu arteritis
300	IgG4-related disease
15	Inclusion body myositis
157	Sturge-Weber syndrome
286	Hereditary sideroblastic anemia
81	Congenital adrenal hyperplasia
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion
187	Kabuki syndrome
323	Aromatic L-amino acid decarboxylase deficiency
288	Autoimmune acquired coagulation factor deficiency
43	Microscopic polyangiitis
274	Osteogenesis Imperfecta
67	Polycystic kidney disease
71	Idiopathic osteonecrosis of the femoral head
212	Tricuspid atresia
77	Growth hormone secreting pituitary adenoma
282	Congenital dyserythropoietic anemia
307	Canavan disease
278	Huge lymphatic malformation with cervicofacial lesion
16	Crow-Fukase syndrome
211	Hypoplastic left heart syndrome
326	Osteopetrosis
47	Buerger disease
114	Non-dystrophic myotonia syndrome
14	Chronic inflammatory demyelinating polyneuropathy
225	Congenital nephrogenic diabetes insipidus
37	Generalised pustular psoriasis
44	Wegener granulomatosis
301	Macular dystrophy
179	Williams syndrome
87	Pulmonary veno-occlusive disease
106	Cryopyrin-associated periodic syndrome
251	Urea cycle disorder
137	Focal cortical dysplasia
192	Cockayne syndrome
277	Lymphangiomatosis
281	Klippel-Trenaunay-Weber syndrome
111	Congenital myopathy
54	Adult still disease
191	Werner syndrome
220	Rapidly progressive glomerulonephritis
30	Distal myopathy