Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abacavir [4] Abacavir; Abacavir sulfate; Triumeq; Ziagen[1] Abacavir 💬--[5] 2, 135, 256, 265, 325 💬
2 Acetate [1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
3 Acetylcarnitine [2] Acetyl-L-carnitine; Acetylcarnitine---[3] 2, 265, 298 💬
4 Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins [1] HB-adMSCs---[5] 2, 6, 13, 14, 46 💬
5 Albumin human [5] Albumin; Human albumin; Human serum albumin; Optison; Serum albumin[1] Albumin human 💬--[3] 2, 78, 96 💬
6 Aldesleukin [4] Aldesleukin; ILT-101; Proleukin; Recombinant human interleukin-2[1] Aldesleukin 💬[3] IL2RA,
IL2RB,
IL2RG 💬		[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[6] 2, 35, 49, 65, 96, 97 💬
7 Alirinetide [2] GM604; GM608---[2] 2, 6 💬
8 Ampicillin [1] ABPC[1] Ampicillin 💬--[5] 2, 6, 13, 84, 299 💬
9 Anakinra [2] Anakinra; Kineret[1] Anakinra 💬[2] IL1R1,
IL1R2 💬		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[18] 2, 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
10 ANX005 [1] ANX005---[3] 2, 8, 61 💬
11 Arimoclomol [1] ARIMOCLOMOL[1] Arimoclomol 💬--[3] 2, 15, 19 💬
12 Arundic acid [1] Arundic Acid[1] Arundic acid 💬--[1] 2 💬
13 Atropine [2] Atropina; Atropine[1] Atropine 💬[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299 💬
14 Baclofen [2] Baclofen; Kemstro[1] Baclofen 💬[2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[8] 2, 10, 13, 18, 65, 70, 149, 206 💬
15 Baricitinib [2] BARICITINIB; Olumiant[1] Baricitinib 💬[2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
16 Basiliximab [2] Basiliximab; Simulect[1] Basiliximab 💬[1] IL2RA 💬[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[6] 2, 50, 66, 97, 222, 228 💬
17 Betamethasone [1] Betamethasone[1] Betamethasone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[8] 2, 28, 46, 65, 83, 90, 96, 235 💬
18 Biotin [4] Biotin; Biotina; D-BIOTIN; Vitamin B7[1] Biotin 💬--[5] 2, 8, 10, 13, 20 💬
19 BLZ-945 [0] ---[1] 2 💬
20 Bosutinib [1] Bosutinib[1] Bosutinib 💬[2] ABL1,
SRC 💬		[49] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 2, 67 💬
21 Botulinum toxin type A [8] Botox; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin[1] Botulinum toxin type A 💬[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
22 Botulinum toxin type B [3] Botulinum toxin type B; MYOBLOC; NEUROBLOC[1] Rimabotulinumtoxin B 💬[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[4] 2, 6, 13, 51 💬
23 Butylphthalide [1] Butylphthalide---[4] 2, 6, 18, 22 💬
24 Caffeine [1] Caffeine[2] Caffeine ,
Caffeine hydrate 💬		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
25 Calusterone [0] [1] Calusterone 💬[1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 2 💬
26 Cannabidiol [4] Cannabidiol; Epidiolex; Epidyolex; Sativex[1] Cannabidiol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
27 Carbonate ion [1] Carbonate---[12] 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299 💬
28 Ceftriaxone [1] Ceftriaxone[1] Ceftriaxone 💬--[4] 2, 6, 46, 97 💬
29 Celecoxib [2] Celebrex; Celecoxib[1] Celecoxib 💬[1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬
30 Censavudine [1] CENSAVUDINE[1] Censavudine 💬--[2] 2, 127 💬
31 Cimetidine [1] Cimetidine[1] Cimetidine 💬[1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 2, 254 💬
32 Ciprofloxacin [2] Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE[1] Ciprofloxacin 💬--[5] 2, 60, 96, 97, 299 💬
33 Clenbuterol [1] Clenbuterol[1] Clenbuterol 💬[1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 1, 2, 6, 13, 256 💬
34 Colchicine [2] COLCHICINA; Colchicine[1] Colchicine 💬[9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[7] 2, 42, 46, 56, 93, 210, 266 💬
35 Copper [2] Copper; Nicotinamide---[4] 2, 169, 170, 171 💬
36 Corticotropin [5] ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin[1] Corticotropin 💬[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[12] 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
37 Creatine [1] Creatine---[11] 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201 💬
38 Creatinine [1] Creatinine[1] Creatinine 💬--[5] 2, 46, 60, 70, 222 💬
39 Cromoglicic acid [4] Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium[1] Cromoglicic acid 💬--[3] 2, 85, 98 💬
40 Curcumin [1] Curcumin---[10] 2, 13, 46, 67, 74, 94, 96, 97, 139, 299 💬
41 Darunavir [1] Darunavir[1] Darunavir 💬--[1] 2 💬
42 Deferiprone [2] Deferiprone; Ferriprox[1] Deferiprone 💬--[6] 2, 6, 18, 120, 122, 233 💬
43 Dexmedetomidine [4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE[1] Dexmedetomidine 💬[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
44 Dexpramipexole [1] Dexpramipexole[1] Dexpramipexole 💬[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 2 💬
45 Dextran [1] Dextran[1] Dextran 1 💬--[4] 2, 62, 96, 97 💬
46 Dextromethorphan [4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[1] Dextromethorphan 💬[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
47 Dextrose, unspecified form [3] Dextrose; Glucose; Smofkabiven---[16] 2, 6, 13, 49, 50, 60, 65, 66, 70, 86, 88, 96, 97, 226, 257, 299 💬
48 Dolutegravir [2] Dolutegravir; Triumeq[1] Dolutegravir 💬--[2] 2, 265 💬
49 Dronabinol [4] Delta-9-tetrahydrocannabinol; DRONABINOL; SATIVEX; Tetrahydrocannabinol[1] Dronabinol 💬[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[8] 2, 8, 13, 36, 46, 96, 271, 298 💬
50 Dutasteride [2] Dutasterida; DUTASTERIDE[1] Dutasteride 💬[2] SRD5A1,
SRD5A2 💬		[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2 💬
51 Edaravone [3] EDARAVONE; Methylphenylpyrazolone; Norphenazone[1] Edaravone 💬--[3] 2, 6, 22 💬
52 Eperisone [1] EPERISONE[1] Eperisone 💬--[1] 2 💬
53 EPI-589 [1] EPI-589---[2] 2, 6 💬
54 Erythropoietin [4] Epoetin alfa; Epoetin beta; Erythropoietin; NeoRecormon---[10] 2, 6, 13, 18, 22, 46, 47, 70, 95, 96 💬
55 Escitalopram [3] Citalopram; Escitalopram; Escitalopram oxalate[1] Escitalopram 💬[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46 💬
56 Esketamine [3] ESKETAMINE; KETAMINE; S-ketamine[1] Esketamine 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[3] 2, 4, 70 💬
57 Ezogabine [4] Ezogabine; Potiga; RETIGABINE; Trobalt[1] Ezogabine 💬[5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬		[6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[2] 2, 144 💬
58 Fasudil [1] Fasudil[1] Fasudil 💬[2] ROCK1,
ROCK2 💬		[23] Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 2, 5, 7, 51 💬
59 Febuxostat [1] Febuxostat[1] Febuxostat 💬[1] XDH 💬[6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[3] 2, 6, 13 💬
60 Fig [1] Fig---[1] 2 💬
61 Filgrastim [7] Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio[1] Filgrastim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
62 GDC-0134 [1] GDC-0134---[1] 2 💬
63 Glatiramer [5] COP-1; COPAXONE; Copolymer-1; Glatiramer; GLATIRAMER ACETATE---[4] 2, 13, 96, 156 💬
64 Gold [1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
65 Guanabenz [1] GUANABENZ[1] Guanabenz 💬[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 2, 13 💬
66 Human interleukin-2 [3] Human interleukin-2; IL-2; INTERLEUKIN-2---[18] 2, 13, 35, 46, 49, 50, 51, 53, 55, 56, 60, 63, 65, 95, 96, 97, 162, 271 💬
67 Human Umbilical Cord Mesenchymal Stem Cells [4] Human Umbilical Cord Mesenchymal Stem Cells; Mesenchymal Stromal Cells; UC-MSCs; WJ-MSCs---[13] 2, 13, 36, 46, 49, 51, 60, 96, 97, 107, 113, 274, 284 💬
68 Ibudilast [1] IBUDILAST[1] Ibudilast 💬[8] CYSLTR1,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PTGIR 💬		[16] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 13 💬
69 Icerguastat [1] Icerguastat---[1] 2 💬
70 Inosine [1] Inosine[1] Inosine 💬--[6] 2, 6, 13, 17, 85, 122 💬
71 Iodide I-123 [2] I 123; I-123---[2] 2, 6 💬
72 Ioflupane I-123 [3] DaTSCAN; Ioflupane; Ioflupane I 123---[3] 2, 5, 6 💬
73 IPL-344 [0] ---[1] 2 💬
74 Ketamine [2] KETAMINE; NMDA[1] Ketamine 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 4, 6, 13, 70, 113, 156, 215 💬
75 Lacosamide [1] Lacosamide[1] Lacosamide 💬[2] SCN3A,
SCN9A 💬		[1] Taste transduction 💬[4] 2, 46, 149, 298 💬
76 Lactose [1] Lactose[2] Anhydrous lactose ,
Lactose 💬		--[6] 2, 6, 13, 97, 228, 310 💬
77 Lamivudine [4] COMBIVIR; Epivir; Lamivudine; Triumeq[1] Lamivudine 💬--[8] 2, 26, 42, 46, 135, 256, 265, 325 💬
78 Latozinemab [2] AL001; Latozinemab[1] Latozinemab 💬[1] SORT1 💬[3] Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬[2] 2, 127 💬
79 Lenograstim [2] G-CSF; LENOGRASTIM[1] Lenograstim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65 💬
80 Lenzumestrocel [1] Lenzumestrocel---[1] 2 💬
81 Leuprolide [3] Leuprolide; Leuprolide acetate depot; Leuprorelin---[6] 1, 2, 3, 51, 67, 76 💬
82 Levetiracetam [2] KEPPRA; Levetiracetam[1] Levetiracetam 💬[1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307 💬
83 Levosimendan [1] LEVOSIMENDAN[1] Levosimendan 💬[2] PDE3A,
PDE3B 💬		[11] Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 2 💬
84 Linoleic acid [1] Linoleic acid---[8] 2, 5, 6, 13, 76, 78, 256, 299 💬
85 Lipoic acid [3] Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid---[5] 2, 5, 13, 14, 20 💬
86 Lithium carbonate [2] Lithium; Lithium Carbonate[1] Lithium carbonate 💬--[5] 2, 13, 17, 18, 127 💬
87 Lithium citrate [2] Lithium; LITHIUM CITRATE[1] Lithium citrate 💬--[5] 2, 5, 6, 7, 8 💬
88 Lunasine [1] Lunasin---[1] 2 💬
89 Masitinib [1] Masitinib[1] Masitinib 💬[1] KIT 💬[11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96 💬
90 Mecobalamin [2] Mecobalamin; Methylcobalamin[1] Mecobalamin 💬--[2] 2, 70 💬
91 Medical Cannabis [3] Cannabis; Marijuana; Medical Cannabis---[7] 2, 6, 13, 19, 90, 96, 97 💬
92 Memantine [3] EBIXA; Memantine; MEMANTINE HYDROCHLORIDE[1] Memantine 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
93 Metformin [5] Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine[1] Metformin 💬[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
94 Methamidophos [1] MONITOR---[4] 2, 11, 81, 129 💬
95 Methane [1] Methane---[1] 2 💬
96 Methylprednisolone [4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] Methylprednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
97 Mexiletine [4] Mexiletina; Mexiletine; Mexitil; Namuscla[1] Mexiletine 💬[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 1, 2, 10, 113, 114 💬
98 Midazolam [2] Midazolam; Midazolam injection[1] Midazolam 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
99 Minocycline [3] Minocycline; Minocycline hydrochloride; Minomycin[1] Minocycline 💬--[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 💬
100 Moxifloxacin [2] Moxifloxacin; Moxifloxacin Hydrochloride[1] Moxifloxacin 💬--[9] 2, 6, 46, 49, 85, 86, 113, 240, 299 💬
101 Mycophenolate mofetil [3] CELLCEPT; Mycophenolate Mofetil; Mycophenolate mofetil TEVA[1] Mycophenolate mofetil 💬[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
102 Mycophenolic acid [5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic[1] Mycophenolic acid 💬[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
103 Nicotinamide [3] Multivitamin; Niacinamide; NICOTINAMIDE[1] Niacinamide 💬--[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
104 Nicotinamide riboside [1] Nicotinamide Riboside---[5] 2, 6, 18, 97, 191 💬
105 Olanzapine [2] OLANZAPINE; Zyprexa[1] Olanzapine 💬[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8 💬
106 Olesoxime [1] OLESOXIME[1] Olesoxime 💬--[3] 2, 3, 13 💬
107 Ozanezumab [1] Ozanezumab[1] Ozanezumab 💬[1] RTN4 💬[1] Alzheimer disease 💬[1] 2 💬
108 Palmidrol [1] Palmitoylethanolamide[1] Palmidrol 💬--[1] 2 💬
109 Pegcetacoplan [2] Aspaveli; PEGCETACOPLAN[1] Pegcetacoplan 💬[1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[4] 2, 61, 62, 222 💬
110 Perampanel [2] Fycompa; PERAMPANEL[1] Perampanel 💬[4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[3] 2, 6, 144 💬
111 Phenylbutyric acid [4] 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate---[14] 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338 💬
112 Phosphate ion [1] Phosphate---[32] 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299 💬
113 Pimozide [1] Pimozide[1] Pimozide 💬[2] ADRA2A,
DRD2 💬		[9] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 2 💬
114 Pioglitazone [1] Pioglitazone[1] Pioglitazone 💬[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
115 Pleconaril [1] PLECONARIL[1] Pleconaril 💬--[1] 2 💬
116 Pramipexole [7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[1] Pramipexole 💬[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20 💬
117 Prednisone [3] Prednisona; Prednisone; RAYOS[1] Prednisone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
118 Pridopidine [1] Pridopidine[1] Pridopidine 💬[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8 💬
119 Primidone [1] Primidone[1] Primidone 💬--[1] 2 💬
120 Pyrazole [2] 1H-Pyrazol; Pyrazole---[6] 2, 28, 46, 58, 75, 154 💬
121 Pyrimethamine [2] Daraprim; Pyrimethamine[1] Pyrimethamine 💬--[12] 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265 💬
122 Quinidine [4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate[1] Quinidine 💬[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13 💬
123 Rabeprazole [1] Rabeprazole[1] Rabeprazole 💬[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 2, 51 💬
124 Ranolazine [3] RANEXA; Ranolazina; RANOLAZINE[1] Ranolazine 💬--[6] 2, 58, 86, 96, 113, 114 💬
125 Rasagiline [4] Azilect; Rasagilina; Rasagiline; Rasagiline mesylate[2] Rasagiline ,
Rasagiline tartrate 💬		[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[6] 2, 5, 6, 17, 58, 66 💬
126 Ravulizumab [2] RAVULIZUMAB; Ultomiris[1] Ravulizumab 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 2, 11, 13, 50, 62, 66, 109 💬
127 Reldesemtiv [2] CK-2127107; Reldesemtiv[1] Reldesemtiv 💬[1] TNNC2 💬[1] Calcium signaling pathway 💬[2] 2, 3 💬
128 Resveratrol [1] Resveratrol---[6] 2, 8, 18, 89, 97, 113 💬
129 Ribavirin [2] Copegus; RIBAVIRIN[1] Ribavirin 💬--[2] 2, 96 💬
130 Riluzole [2] Rilutek; Riluzole[1] Riluzole 💬[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
131 Ritonavir [2] Norvir; Ritonavir[1] Ritonavir 💬--[3] 2, 86, 265 💬
132 Ropinirole [3] Requip; Ropinirole; ROPINIROLE HYDROCHLORIDE[1] Ropinirole 💬[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309 💬
133 Scopolamine [1] Scopolamine[1] Scopolamine 💬[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 2 💬
134 Serine [2] L-Serine; Serine[1] Serine 💬--[4] 2, 6, 86, 96 💬
135 Serotonin [1] Serotonin---[3] 2, 96, 97 💬
136 Sirolimus [3] Rapamune; Rapamycin; Sirolimus[1] Sirolimus 💬[1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
137 Sodium lauryl sulfate [0] [1] Sodium lauryl sulfate 💬--[1] 2 💬
138 Somatotropin [17] Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton---[25] 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337 💬
139 Sulfate ion [1] Sulfate---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299 💬
140 Tacrolimus [2] Prograf; TACROLIMUS[2] Tacrolimus ,
Tacrolimus 💬		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
141 Talampanel [1] Talampanel[1] Talampanel 💬[4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[2] 2, 6 💬
142 Tamoxifen [2] TAMOXIFEN; TAMOXIFEN CITRATE[1] Tamoxifen 💬[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[3] 2, 113, 227 💬
143 Tauroursodeoxycholic acid [4] Tauroursodeoxycholic acid; Taurursodiol; TUDCA; Ursodoxicoltaurine[1] Taurursodiol 💬--[3] 2, 93, 299 💬
144 Tenofovir [1] Tenofovir[1] Tenofovir 💬--[6] 2, 13, 25, 93, 265, 325 💬
145 Tenofovir alafenamide [1] Tenofovir alafenamide[1] Tenofovir alafenamide 💬--[2] 2, 13 💬
146 Testosterone [1] Testosterone[1] Testosterone 💬[1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[8] 1, 2, 3, 13, 60, 76, 78, 113 💬
147 Thalidomide [1] Thalidomide[1] Thalidomide 💬[1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
148 Tirasemtiv [1] Tirasemtiv[1] Tirasemtiv 💬--[1] 2 💬
149 Tocilizumab [3] Actemra; RoActemra; Tocilizumab[1] Tocilizumab 💬[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
150 Tofersen [1] Tofersen[1] Tofersen 💬[1] SOD1 💬[8] Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬[1] 2 💬
151 Trametinib [2] Mekinist; Trametinib[1] Trametinib 💬[2] MAP2K1,
MAP2K2 💬		[89] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[4] 2, 34, 279, 280 💬
152 Trazodone [1] Trazodone[1] Trazodone 💬[4] HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 2 💬
153 Trehalose [2] Cabaletta; Trehalose---[4] 2, 6, 18, 113 💬
154 Tretinoin [5] ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID[1] Tretinoin 💬[3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[6] 2, 62, 63, 75, 94, 231 💬
155 Triheptanoin [1] Triheptanoin[1] Triheptanoin 💬--[10] 2, 8, 65, 149, 156, 248, 256, 257, 317, 324 💬
156 Trimetazidine [1] Trimetazidine[1] Trimetazidine 💬--[3] 2, 58, 86 💬
157 Ubidecarenone [3] Coenzyme Q-10; Coenzyme Q10; CoQ10[1] Ubidecarenone 💬--[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 💬
158 Valproic acid [3] Valproate; VALPROATE SODIUM; Valproic Acid[1] Valproic acid 💬[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
159 Verdiperstat [1] Verdiperstat[1] Verdiperstat 💬[1] MPO 💬[5] Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬[3] 2, 17, 127 💬
160 Vitamin E [2] Alpha-tocopherol; Vitamin E[1] Vitamin E 💬--[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
161 Water [8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION[1] Water 💬--[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
162 Zilucoplan [1] ZILUCOPLAN[1] Zilucoplan 💬[1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 2, 11, 62 💬
163 Zinc [3] Nicotinamide; Wilzin; Zinc---[4] 2, 113, 171, 299 💬