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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Acetate1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
2ALX-0081----1件: 64
3ALX0081----1件: 64
4Anfibatide1件: Anfibatide---1件: 64
5Anti-CD20 antibody----1件: 64
6Anti-von Willebrand Factor Nanobody1件: Von Willebrand factor human---1件: 64
7Anti-von Willebrand Factor Nanobody, Caplacizumab2件: Caplacizumab,
Von Willebrand factor human		1件: D11160 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
8Anti-von Willebrand Factor Nanobody, INN = Caplacizumab2件: Caplacizumab,
Von Willebrand factor human		1件: D11160 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
9Apadamtase alfa1件: Apadamtase alfa---1件: 64
10Apademtase alfa----1件: 64
11ARC 1779----2件: 64, 288
12ARC1779----2件: 64, 288
13ARC1779 Injection----2件: 64, 288
14Aspirin1件: Acetylsalicylic acid1件: D00109 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬12件: 13, 22, 46, 49, 51, 58, 64, 86, 113, 158, 210, 231
15Aspirin tablet1件: Acetylsalicylic acid1件: D00109 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 64
16BAX930----1件: 64
17BAX930 - RECOMBINANT HUMAN ADAMTS13----1件: 64
18BAX930 or SHP655----1件: 64
19BAX930 or SHP655 or TAK755----1件: 64
20BORTEZOMIB1件: Bortezomib1件: D03150 1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331
21Bortezomib Injection1件: Bortezomib1件: D03150 1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬1件: 64
22CABLIVI1件: Caplacizumab1件: D11160 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
23Cablivi®1件: Caplacizumab1件: D11160 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
24CAPLACIZUMAB1件: Caplacizumab1件: D11160 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
25Caplacizumab (ALX-0081)1件: Caplacizumab1件: D11160 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
26Caplacizumab (an anti-von Willebrand Factor Nanobody ALX-0081)2件: Caplacizumab,
Von Willebrand factor human		1件: D11160 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
27Caplacizumab (an anti-von Willebrand Factor Nanobody)2件: Caplacizumab,
Von Willebrand factor human		1件: D11160 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
28Corticosteroid treatment (Methylprednisolone or prednisolone)2件: Methylprednisolone,
Prednisolone		2件: D00407 ,
D00472 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 64
29Corticosteroids----12件: 41, 46, 49, 63, 64, 97, 107, 113, 164, 220, 296, 300
30Cryosupernatant plasma----1件: 64
31Cyclosporine1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
32Danazol1件: Danazol1件: D00289 3件: AR,
ESR1,
PGR 💬		12件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬5件: 60, 63, 64, 65, 285
33Desmopressin1件: Desmopressin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬5件: 6, 64, 72, 225, 288
34Desmopressin acetate2件: Acetate,
Desmopressin		1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 64, 288
35Dexamethasone1件: Dexamethasone1件: D00292 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
36HMED-IdeS1件: Imlifidase1件: D11470 --2件: 64, 221
37IDEC-C2B8, Ro 45-2294----1件: 64
38IdeS1件: Imlifidase1件: D11470 --2件: 64, 221
39IdeS (0.25 mg/kg)1件: Imlifidase1件: D11470 --1件: 64
40IdeS (0.50 mg/kg)1件: Imlifidase1件: D11470 --1件: 64
41Immunosuppressive treatment (eg, rituximab)1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬1件: 64
42MabThera1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬22件: 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271
43Magnesium1件: Magnesium---15件: 6, 11, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298
44MASP-2 antibody1件: Narsoplimab1件: D11531 1件: MASP2 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬3件: 64, 66, 109
45Methylprednisolone1件: Methylprednisolone1件: D00407 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
46Minirin1件: Desmopressin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 64, 288
47Nanobody directed towards the human A1 domain of von Willebrand factor1件: Von Willebrand factor human---1件: 64
48Octaplas1件: Plasma protein fraction (human)---1件: 64
49Octaplas infusion1件: Plasma protein fraction (human)---1件: 64
50Octaplas SD1件: Plasma protein fraction (human)---1件: 64
51OctaplasLG®----1件: 64
52Octaplas®LG1件: Plasma protein fraction (human)---1件: 64
53Octostim----2件: 64, 288
54OMS721----3件: 64, 66, 109
55OMS721 100 mg/ml Injection solution, OMS00620646, OMS620646, MASP-2 Antibody1件: Narsoplimab1件: D11531 1件: MASP2 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬2件: 64, 109
56OMS721 185 mg/ml Injection solution, OMS00620646, OMS620646, MASP-2 Antibody1件: Narsoplimab1件: D11531 1件: MASP2 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬2件: 64, 109
57Plasma exchange (PE)----1件: 64
58Pooled Plasma (Human), Solvent/Detergent Treated----1件: 64
59PREDNISOLONE1件: Prednisolone1件: D00472 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
60Prednisone1件: Prednisone1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
61RADAMTS-13----1件: 64
62Recombinant A Disintegrin and Metalloproteinase Thrombospondin Type-1 Motifs 13----1件: 64
63Recombinant A Disintegrin and Metalloproteinase with Thrombospondin Type-1----1件: 64
64Recombinant A Disintegrin and Metalloproteinase with Thrombospondin Type-1 Motifs----1件: 64
65Recombinant A Disintegrin and Metalloproteinase with Thrombospondin Type-1 Motifs 13----1件: 64
66Recombinant A Disintegrin And Metalloproteinase with Thrombospondin Type-1 Motifs 13 (rADAMTS13)----1件: 64
67Recombinant ADAMTS13----1件: 64
68RITUXIMAB1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
69Romiplostim1件: Romiplostim1件: D08990 1件: MPL 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬4件: 60, 63, 64, 65
70SHP 655 (BAX 930)----1件: 64
71SHP655----1件: 64
72Standard of Care----8件: 6, 13, 49, 51, 63, 64, 79, 171
73Standard Plasma----1件: 64
74Standrd of Care treatment----1件: 64
75Sulfate1件: Sulfate ion---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299
76Sulfate, Magnesium2件: Magnesium,
Sulfate ion		---1件: 64
77TAK-755----1件: 64
78TAK-755 or BAX930 or SHP655----1件: 64
79TAK-755 orBAX930 or SHP655----1件: 64
80Uniplas----1件: 64
81Von willebrand factor1件: Von Willebrand factor human---2件: 64, 288