Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abacavir 4件: Abacavir; Abacavir sulfate; Triumeq; Ziagen1件: D07057 --5件: 2, 135, 256, 265, 325
2 Acetate 1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
3 Acetylcarnitine 2件: Acetyl-L-carnitine; Acetylcarnitine---3件: 2, 265, 298
4 Acipimox 1件: Acipimox1件: D07190 --2件: 78, 265
5 Amprenavir 1件: Amprenavir1件: D00894 --1件: 265
6 ANX-510 0件: ---2件: 265, 288
7 Aramchol 1件: Aramchol---1件: 265
8 Atazanavir 2件: Atazanavir; Reyataz1件: D07471 --1件: 265
9 Atorvastatin 3件: ATORVASTATIN; Atorvastatin calcium; Lipitor1件: D07474 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
10 Baricitinib 2件: Baricitinib; Olumiant1件: D10308 2件: JAK1,
JAK2 💬		35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬13件: 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
11 Berberine 1件: Berberine---2件: 97, 265
12 Caffeine 1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
13 Calcium 2件: Calcio; Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
14 Cholic Acid 1件: Cholic Acid1件: D10699 1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 234, 265, 310
15 Didanosine 1件: Didanosine1件: D00296 --2件: 25, 265
16 Diosmin 1件: DIOSMIN1件: D07858 --3件: 46, 97, 265
17 Dolutegravir 2件: Dolutegravir; Triumeq1件: D10066 --2件: 2, 265
18 Doravirine 1件: Doravirine1件: D10624 --1件: 265
19 Efavirenz 2件: Efavirenz; SUSTIVA1件: D00896 --1件: 265
20 Emtricitabine 2件: Emtricitabine; TRUVADA1件: D01199 --4件: 25, 93, 265, 325
21 Enfuvirtide 1件: Enfuvirtide1件: D02499 --2件: 25, 265
22 Fenofibrate 1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬6件: 8, 79, 93, 94, 97, 265
23 Gemcabene 1件: Gemcabene---2件: 79, 265
24 Indinavir 1件: Indinavir1件: D03833 --1件: 265
25 Lamivudine 4件: COMBIVIR; Epivir; Lamivudine; Triumeq1件: D00353 --8件: 2, 26, 42, 46, 135, 256, 265, 325
26 Leptin 1件: Leptin---2件: 6, 265
27 Levocarnitine 4件: Carnitine; L-Carnitine; Levocarnitine; Xyzal1件: D02176 --11件: 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
28 Lopinavir 2件: Kaletra; Lopinavir1件: D01425 --2件: 93, 265
29 Mecasermin 3件: Increlex; Mecasermin; MECASERMINA1件: D03297 2件: GHR,
IGF1R 💬		33件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬6件: 65, 78, 96, 168, 265, 299
30 Metformin 5件: Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine1件: D04966 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
31 Metreleptin 3件: METRELEPTIN; Myalept; R-metHuLeptin1件: D05014 1件: LEPR 💬6件: AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬1件: 265
32 Nelfinavir 1件: Nelfinavir1件: D08259 --3件: 49, 265, 331
33 Nevirapine 1件: Nevirapine1件: D00435 --1件: 265
34 Obeticholic acid 4件: 6-ECDCA; 6-ethylchenodeoxycholic acid; OBETICHOLIC ACID; Ocaliva1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬3件: 93, 265, 296
35 Pegvisomant 1件: Pegvisomant1件: D05394 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬2件: 78, 265
36 Pioglitazone 1件: Pioglitazone1件: D08378 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
37 Pravastatin 2件: Pravastatin; Pravastatin sodium1件: D08410 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 13, 46, 49, 67, 79, 96, 164, 265, 333
38 Pyrimethamine 2件: Daraprim; PYRIMETHAMINE1件: D00488 --12件: 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265
39 Raltegravir 2件: ISENTRESS; Raltegravir1件: D06676 --4件: 13, 26, 93, 265
40 Riboflavin 2件: Riboflavin; Vitamin B21件: D00050 --7件: 38, 46, 96, 97, 162, 168, 265
41 Ritonavir 2件: Norvir; Ritonavir1件: D00427 --3件: 2, 86, 265
42 Rosiglitazone 2件: Rosiglitazone; Rosiglitazone maleate1件: D08491 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬5件: 46, 75, 97, 222, 265
43 Saquinavir 1件: Saquinavir1件: D00429 --2件: 86, 265
44 Setmelanotide 1件: Setmelanotide1件: D11927 1件: MC4R 💬1件: Neuroactive ligand-receptor interaction 💬2件: 202, 265
45 Simvastatin 3件: Simvastatin; Simvastatina; Simvastatine1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
46 Somatotropin 17件: Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton---25件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337
47 Stavudine 1件: Stavudine1件: D00445 --1件: 265
48 Sulfate ion 1件: Sulfate---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299
49 Tenofovir 1件: Tenofovir1件: D06074 --6件: 2, 13, 25, 93, 265, 325
50 Tenofovir disoproxil 4件: Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA---2件: 93, 265
51 Tesamorelin 2件: GHRH; Tesamorelin1件: D06655 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 78, 265
52 Thiamine 2件: Thiamine; Vitamin B11件: D08580 --4件: 8, 93, 145, 265
53 Tipranavir 1件: Tipranavir1件: D08605 --1件: 265
54 Volanesorsen 1件: Volanesorsen1件: D11648 1件: APOC3 💬2件: Cholesterol metabolism, PPAR signaling pathway 💬1件: 265
55 Zidovudine 3件: COMBIVIR; Retrovir; Zidovudine1件: D00413 --7件: 25, 26, 94, 135, 265, 325, 331