Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Serine 1件: Serine2件: L-Serine; Serine; --4件: 2, 6, 86, 96
2 Sucrose 1件: Sucrose1件: Sucrose; --3件: 62, 96, 97
3 Sorbitol solution 1件: Sorbitol3件: D-glucitol; D-SORBITOL; Sorbitol; --3件: 10, 28, 299
4 Salicylic acid 1件: Salicylic acid2件: 2-Hydroxybenzoic acid; Salicylic acid; --1件: 97
5 Sulindac 1件: Sulindac1件: Sulindac; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 206
6 Scopolamine 1件: Scopolamine1件: Scopolamine; 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 2
7 Salsalate 1件: Salsalate1件: Salsalate; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5
8 Saquinavir 1件: Saquinavir1件: Saquinavir; --2件: 86, 265
9 Simvastatin 1件: Simvastatin3件: Simvastatin; Simvastatina; Simvastatine; 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
10 Spironolactone 1件: Spironolactone1件: Spironolactone; 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬8件: 46, 58, 67, 86, 113, 210, 218, 225
11 Stanozolol 1件: Stanozolol1件: Stanozolol; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 60
12 Stavudine 1件: Stavudine1件: Stavudine; --1件: 265
13 Sucralfate 1件: Sucralfate1件: Sucralfate; --1件: 98
14 Sulfamethoxazole 1件: Sulfamethoxazole3件: Bactrim; Sulfamethoxazole; Sulphamethoxazole; --5件: 44, 49, 61, 85, 299
15 Sulfasalazine 1件: Sulfasalazine3件: Salazosulfapyridine; Salicylazosulfapyridine; Sulfasalazine; --6件: 46, 86, 94, 107, 270, 271
16 Sevoflurane 1件: Sevoflurane1件: Sevoflurane; --7件: 6, 21, 22, 34, 98, 225, 296
17 Succimer 1件: Succimer1件: DMSA; --1件: 171
18 Sulfadoxine 1件: Sulfadoxine1件: Sulfadoxine; --1件: 65
19 Sirolimus 1件: Sirolimus3件: RAPAMUNE; Rapamycin; Sirolimus; 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331
20 Sodium fluoride 1件: Sodium fluoride1件: Sodium fluoride; --1件: 51
21 Sodium lauryl sulfate 1件: Sodium lauryl sulfate0件: --1件: 2
22 Sodium bicarbonate 1件: Sodium bicarbonate1件: Sodium Bicarbonate; --1件: 299
23 Sulpiride 1件: Sulpiride0件: 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 70
24 Sodium acetate 1件: Sodium acetate1件: Sodium acetate; --2件: 81, 251
25 Sodium citrate hydrate 1件: Sodium citrate1件: Sodium citrate; --4件: 67, 214, 215, 235
26 Silodosin 1件: Silodosin2件: Silodosin; Silodyx; 1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 6, 13
27 Sodium chloride 1件: Sodium chloride6件: Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium chloride; SPORANOX; --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299
28 Sertraline 1件: Sertraline1件: Sertraline; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206
29 Sesame oil 1件: Sesame oil1件: Sesame oil; --1件: 3
30 Selegiline 1件: Selegiline2件: SELEGILINE; Zelapar; 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
31 Sivelestat 1件: Sivelestat1件: Sivelestat; 1件: ELANE 💬3件: Neutrophil extracellular trap formation, Systemic lupus erythematosus, Transcriptional misregulation in cancer 💬3件: 13, 85, 96
32 Sodium iodide 1件: Sodium iodide1件: Sodium iodide; --1件: 34
33 Sodium iodide I 123 1件: Sodium iodide1件: Sodium iodide; --1件: 34
34 Salmeterol 1件: Salmeterol1件: Salmeterol; 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 299
35 Sargramostim 1件: Sargramostim2件: Leukine; Sargramostim; 1件: CSF2RA 💬4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬7件: 6, 28, 60, 62, 96, 229, 285
36 Simethicone 1件: Simethicone1件: Simethicone; --2件: 13, 96
37 Sodium citrate 1件: Sodium citrate1件: Sodium citrate; --4件: 67, 214, 215, 235
38 Sodium dichloroacetate 1件: Sodium dichloroacetate1件: Dichloroacetate Sodium; 3件: PDK2,
PDK3,
PDK4 💬		1件: Diabetic cardiomyopathy 💬1件: 86
39 Sodium fluoride F 18 1件: Fluorine F-181件: FLUORINE-18; --1件: 41
40 Sodium iodide I 125 1件: Sodium iodide1件: Sodium iodide; --1件: 34
41 Sodium oxybate 1件: Sodium oxybate1件: Sodium Oxybate; --2件: 6, 149
42 Sodium sulfate 1件: Sodium sulfate1件: Sodium sulfate; --1件: 28
43 Stamulumab 1件: Stamulumab1件: MYO-029; 1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 113
44 Stannsoporfin 1件: Stannsoporfin1件: Tin mesoporphyrin; 2件: HMOX1,
HMOX2 💬		10件: Chemical carcinogenesis - reactive oxygen species, Ferroptosis, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatocellular carcinoma, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Pathways in cancer, Porphyrin metabolism 💬1件: 254
45 Stiripentol 1件: Stiripentol2件: DIACOMIT; Stiripentol; --1件: 140
46 Sufentanil 1件: Sufentanil1件: Sufentanil; 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬2件: 70, 280
47 Sulfachlorpyridazine 1件: Sulfachlorpyridazine0件: --1件: 6
48 Sulfur hexafluoride 1件: Sulfur hexafluoride3件: SonoVue; Sulfur hexafluoride; Sulphur hexafluoride; --2件: 96, 215
49 Senna leaf 1件: Senna leaf1件: Senna; --1件: 291
50 Sodium tetradecyl sulfate 1件: Sodium tetradecyl sulfate0件: --2件: 50, 51
51 Sitaxentan 1件: Sitaxentan3件: Sitaxentan; Sitaxsentan; Thelin; 1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
52 Somatostatin 1件: Somatostatin1件: Somatostatin; 5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬		4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 67, 78
53 Strontium ranelate 1件: Strontium ranelate1件: Strontium ranelate; --1件: 78
54 Sapropterin 1件: Sapropterin5件: 6R-BH4; KUVAN; Sapropterin; SAPROPTERIN DIHYDROCHLORIDE; Tetrahydrobiopterin; --5件: 51, 86, 124, 240, 299
55 Sevelamer 1件: Sevelamer1件: Sevelamer; --2件: 235, 238
56 Sildenafil 1件: Sildenafil6件: Mysildecard; Revatio; SILDENAFIL; Sildenafil Citrate; SILDENAFILO; VIAGRA; 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
57 Sitagliptin 1件: Sitagliptin1件: Sitagliptin; 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299
58 Solifenacin 1件: Solifenacin2件: Solifenacin; Solifenacin Succinate; 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬3件: 6, 13, 53
59 Somatorelin 1件: Somatorelin2件: GHRH; Somatorelin; 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 13, 78
60 Sorafenib 1件: Sorafenib2件: Nexavar; Sorafenib; 8件: BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬		89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬2件: 34, 86
61 Spectinomycin 1件: Spectinomycin0件: --1件: 13
62 Sulfanilamide 1件: Sulfanilamide0件: --4件: 6, 30, 60, 298
63 Sulodexide 1件: Sulodexide0件: 2件: SERPINC1,
SERPIND1 💬		1件: Complement and coagulation cascades 💬2件: 51, 271
64 Sunitinib 1件: Sunitinib2件: Sunitinib; Sunitinib malate; 9件: CSF1R,
FLT1,
FLT3,
FLT4,
KDR,
KIT,
PDGFRA,
PDGFRB,
RET 💬		36件: Acute myeloid leukemia, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬2件: 28, 34
65 Saxagliptin 1件: Saxagliptin1件: Saxagliptin; 1件: DPP4 💬1件: Protein digestion and absorption 💬1件: 299
66 Sinecatechins 1件: Sinecatechins1件: Veregen; --1件: 160
67 Sunflower oil 1件: Sunflower oil1件: Sunflower oil; --2件: 46, 299
68 Serlopitant 1件: Serlopitant1件: Serlopitant; 1件: TACR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 36
69 Sobetirome 1件: Sobetirome1件: Sobetirome; 1件: THRB 💬2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 20
70 Saracatinib 1件: Saracatinib1件: Saracatinib; 2件: ABL1,
SRC 💬		49件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬3件: 6, 89, 272
71 Selumetinib 1件: Selumetinib2件: Koselugo; Selumetinib; 2件: MAP2K1,
MAP2K2 💬		89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 34
72 Sifalimumab 1件: Sifalimumab1件: Sifalimumab; 13件: IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬		25件: Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬1件: 49
73 Siltuximab 1件: Siltuximab1件: Siltuximab; 1件: IL6 💬51件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 28, 331
74 Sotatercept 1件: Sotatercept1件: SOTATERCEPT; 1件: ACVR2A 💬4件: Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬2件: 86, 284
75 Sotrastaurin 1件: Sotrastaurin1件: Sotrastaurin; 4件: PRKCD,
PRKCE,
PRKCH,
PRKCQ 💬		29件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Aldosterone synthesis and secretion, Apelin signaling pathway, Autophagy - animal, C-type lectin receptor signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Diabetic cardiomyopathy, Estrogen signaling pathway, Fc gamma R-mediated phagocytosis, GnRH signaling pathway, Inflammatory mediator regulation of TRP channels, Insulin resistance, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Prion disease, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 97
76 Secukinumab 1件: Secukinumab2件: COSENTYX; SECUKINUMAB; 1件: IL17A 💬6件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬8件: 13, 37, 41, 46, 107, 160, 269, 271
77 Selexipag 1件: Selexipag2件: SELEXIPAG; Uptravi; 1件: PTGIR 💬3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬5件: 51, 70, 84, 86, 88
78 Semaglutide 1件: Semaglutide1件: Semaglutide; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 6
79 Sirukumab 1件: Sirukumab1件: Sirukumab; 1件: IL6 💬51件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 41, 46
80 Suvorexant 1件: Suvorexant1件: Suvorexant; 2件: HCRTR1,
HCRTR2 💬		1件: Neuroactive ligand-receptor interaction 💬3件: 5, 6, 13
81 Safinamide 1件: Safinamide3件: Safinamida; SAFINAMIDE; Xadago; 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬2件: 6, 17
82 Sarilumab 1件: Sarilumab4件: KEVZARA; REGN88; SAR153191; SARILUMAB; 1件: IL6R 💬12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬5件: 41, 46, 84, 107, 271
83 Sacubitril 1件: Sacubitril2件: Entresto; Sacubitril; 1件: MME 💬4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬2件: 58, 222
84 Sofosbuvir 1件: Sofosbuvir1件: Sofosbuvir; --1件: 19
85 Sebelipase alfa 1件: Sebelipase alfa4件: KANUMA; SBC-102; Sebelipasa Alfa; Sebelipase Alfa; 1件: LIPA 💬3件: Cholesterol metabolism, Lysosome, Steroid biosynthesis 💬1件: 19
86 Sodium glycerophosphate 1件: Sodium glycerophosphate1件: Smofkabiven; --1件: 66
87 Susoctocog alfa 1件: Susoctocog alfa1件: OBIZUR; --1件: 288
88 Selonsertib 1件: Selonsertib1件: Selonsertib; 1件: MAP3K5 💬20件: Alcoholic liver disease, Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Huntington disease, Lipid and atherosclerosis, MAPK signaling pathway, Neurotrophin signaling pathway, Non-alcoholic fatty liver disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Protein processing in endoplasmic reticulum, Sphingolipid signaling pathway, Spinocerebellar ataxia, TNF signaling pathway, Thermogenesis, Tight junction 💬1件: 86
89 Somatrogon 1件: Somatrogon2件: Ngenla; Somatrogon; --1件: 78
90 Satralizumab 1件: Satralizumab3件: Enspryng; Sapelizumab; SATRALIZUMAB; 1件: IL6R 💬12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬3件: 11, 13, 86
91 Somavaratan 1件: Somavaratan1件: Somavaratan; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
92 Somapacitan 1件: Somapacitan2件: Sogroya; Somapacitan; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬2件: 78, 195
93 Selinexor 1件: Selinexor1件: Selinexor; 1件: XPO1 💬5件: Human T-cell leukemia virus 1 infection, Influenza A, Nucleocytoplasmic transport, Ribosome biogenesis in eukaryotes, Viral life cycle - HIV-1 💬1件: 28
94 Seladelpar 1件: Seladelpar1件: SELADELPAR; 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94
95 Siponimod 1件: Siponimod2件: Mayzent; Siponimod; 2件: S1PR1,
S1PR5 💬		3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬2件: 13, 50
96 Sutimlimab 1件: Sutimlimab1件: Sutimlimab; 1件: C1S 💬5件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 61
97 Soticlestat 1件: Soticlestat1件: SOTICLESTAT; 1件: CYP46A1 💬1件: Primary bile acid biosynthesis 💬2件: 140, 144
98 Sparsentan 1件: Sparsentan1件: SPARSENTAN; 2件: AGTR1,
EDNRA 💬		17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222
99 Sibofimloc 1件: Sibofimloc1件: Sibofimloc; --1件: 96
100 Setmelanotide 1件: Setmelanotide1件: Setmelanotide; 1件: MC4R 💬1件: Neuroactive ligand-receptor interaction 💬2件: 202, 265
101 Spesolimab 1件: Spesolimab1件: Spesolimab; 1件: IL1RL2 💬1件: Cytokine-cytokine receptor interaction 💬3件: 37, 96, 97