Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Carbon dioxide 1件: Carbon dioxide1件: Carbon dioxide; --2件: 97, 158
2 Cholesterol 1件: Cholesterol1件: Cholesterol; --6件: 8, 19, 90, 160, 222, 310
3 Cobamamide 1件: Cobamamide1件: Cobamamide; --1件: 299
4 Citicoline 1件: Citicoline1件: Citicolina; --1件: 6
5 Calcifediol 1件: Calcifediol2件: 25-Hydroxyvitamin D3; CALCIFEDIOL; 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 113, 299
6 Calcitriol 1件: Calcitriol1件: Calcitriol; 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬9件: 18, 37, 46, 49, 66, 96, 158, 235, 326
7 Corticotropin 1件: Corticotropin5件: ACTH; Acthar; Adrenocorticotropic Hormone; Corticotrophin; Corticotropin; 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬12件: 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222
8 Chenodiol 1件: Chenodeoxycholic acid3件: CDCA; Chenodeoxycholic Acid; Chenodiol; 1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 96, 234, 263
9 Cyanocobalamin 1件: Cyanocobalamin2件: Cianocobalamina; Vitamin B12; --5件: 6, 13, 201, 229, 299
10 Cytarabine 1件: Cytarabine1件: Cytarabine; --7件: 11, 13, 14, 25, 49, 60, 65
11 Cyclosporine 1件: Cyclosporine10件: CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis; 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
12 Ciprofloxacin 1件: Ciprofloxacin2件: CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE; --5件: 2, 60, 96, 97, 299
13 Cholecalciferol 1件: Cholecalciferol5件: CHOLECALCIFEROL; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3; 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
14 Capsaicin 1件: Capsaicin2件: Capsaicin; Qutenza; 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226
15 Captopril 1件: Captopril1件: Captopril; 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬8件: 6, 17, 46, 86, 96, 97, 107, 271
16 Carbamazepine 1件: Carbamazepine1件: Carbamazepine; 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 6, 13, 231
17 Carmustine 1件: Carmustine1件: Carmustine; --5件: 11, 13, 14, 28, 60
18 Carvedilol 1件: Carvedilol1件: CARVEDILOL; 5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		13件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 57, 86, 113, 210
19 Cefadroxil 1件: Cefadroxil0件: --2件: 222, 240
20 Cefuroxime 1件: Cefuroxime2件: Cefuroxim; CEFUROXIME; --2件: 97, 299
21 Cefalexin 1件: Cephalexin2件: CEFALEXIN; Cephalexin; --1件: 299
22 Chlorambucil 1件: Chlorambucil1件: Chlorambucil; --1件: 222
23 Chlormezanone 1件: Chlormezanone0件: --1件: 13
24 Chlorpromazine 1件: Chlorpromazine2件: Chlorpromazine; Chlorpromazine Hydrochloride; 13件: ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬		22件: Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 254
25 Cidofovir 1件: Cidofovir1件: Cidofovir; --1件: 25
26 Cisapride 1件: Cisapride1件: CISAPRIDE; 3件: HTR2A,
HTR3A,
HTR4 💬		7件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 13
27 Cisplatin 1件: Cisplatin1件: Cisplatin; --1件: 28
28 Clarithromycin 1件: Clarithromycin1件: Clarithromycin; --8件: 6, 63, 84, 96, 97, 222, 228, 299
29 Clindamycin 1件: Clindamycin2件: Clindamycin; Dalacin C phosphate; --2件: 46, 299
30 Clofazimine 1件: Clofazimine1件: CLOFAZIMINE; --1件: 96
31 Clonazepam 1件: Clonazepam1件: Clonazepam; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6
32 Clonidine 1件: Clonidine4件: Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE; 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
33 Clotrimazole 1件: Clotrimazole1件: Clotrimazole; --1件: 97
34 Clozapine 1件: Clozapine1件: CLOZAPINE; 11件: ADRA2A,
ADRA2B,
ADRA2C,
DRD4,
HTR2A,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		8件: Calcium signaling pathway, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬1件: 6
35 Cosyntropin 1件: Tetracosactide4件: Cosyntropin; Synacthen Depot; TETRACOSACTIDE; Tetracosactrin; 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 78, 83, 113, 145, 222
36 Cyclophosphamide 1件: Cyclophosphamide6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; CYCLOPHOSPHAMIDE; Cyclophosphamidum; Cytoxan; --44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
37 Cimetidine 1件: Cimetidine1件: Cimetidine; 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 2, 254
38 Chlorothiazide 1件: Chlorothiazide1件: Chlorothiazide; 1件: SLC12A3 💬-1件: 225
39 Candesartan 1件: Candesartan1件: CANDESARTAN; 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 58, 67
40 Caffeine 1件: Caffeine1件: Caffeine; 11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
41 Carbidopa 1件: Carbidopa8件: Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo; 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 6, 13, 17, 90, 140, 164, 201
42 Celecoxib 1件: Celecoxib2件: Celebrex; Celecoxib; 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
43 Colchicine 1件: Colchicine2件: COLCHICINA; Colchicine; 9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬7件: 2, 42, 46, 56, 93, 210, 266
44 Candesartan cilexetil 1件: Candesartan cilexetil1件: CANDESARTAN; 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 67
45 Cephalexin 1件: Cephalexin2件: CEFALEXIN; Cephalexin; --1件: 299
46 Ceftazidime 1件: Ceftazidime3件: Ceftazidim; Ceftazidima; CEFTAZIDIME; --1件: 299
47 Calcium carbonate 1件: Calcium carbonate3件: Calcio carbonato; Calcium; Calcium carbonate; --9件: 13, 19, 46, 53, 75, 96, 235, 274, 299
48 Calcium citrate 1件: Calcium citrate1件: Calcium citrate; --3件: 46, 84, 235
49 Calcium gluconate 1件: Calcium gluconate1件: Calcium gluconate; --3件: 214, 215, 235
50 Calcium lactate 1件: Calcium lactate1件: Calcium lactate; --1件: 235
51 Cortisone acetate 1件: Cortisone acetate1件: Cortisone acetate; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
52 Cabergoline 1件: Cabergoline3件: CABERGOLINA; Cabergoline; DOSTINEX; 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 74, 75
53 Cepharanthine 1件: Cepharanthine2件: Cepharanthin; Cepharanthine; --1件: 53
54 Cilazapril 1件: Cilazapril1件: Cilazapril; 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 66
55 Calcipotriene 1件: Calcipotriol2件: Calcipotriene; CALCIPOTRIOL; 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 36, 51
56 Cilnidipine 1件: Cilnidipine1件: Cilnidipine; 5件: CACNA1B,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		41件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Nicotine addiction, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 67
57 Citric acid monohydrate 1件: Citric acid1件: Citric acid; --2件: 53, 291
58 Clobazam 1件: Clobazam1件: CLOBAZAM; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 140, 144
59 Clobetasol propionate 1件: Clobetasol propionate1件: Clobetasol propionate; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 46, 162
60 Carboplatin 1件: Carboplatin2件: Carboplatin; CBDCA; --4件: 28, 34, 60, 85
61 Cladribine 1件: Cladribine4件: 2-CdA; CLADRIBINA; CLADRIBINE; MAVENCLAD; 1件: RRM1 💬6件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬3件: 11, 13, 94
62 Caffeine hydrate 1件: Caffeine1件: Caffeine; 11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
63 Ciclesonide 1件: Ciclesonide1件: Ciclesonide; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 84
64 Cilostazol 1件: Cilostazol2件: CILOSTAZOL; PLETAL; 3件: PDE3A,
PDE3B,
TBXA2R 💬		14件: Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 46, 51, 70
65 Cisapride 1件: Cisapride1件: CISAPRIDE; 3件: HTR2A,
HTR3A,
HTR4 💬		7件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 13
66 Calcium lactate hydrate 1件: Calcium lactate1件: Calcium lactate; --1件: 235
67 Cefazolin 1件: Cefazolin1件: Cefazolin; --1件: 291
68 Cefadroxil 1件: Cefadroxil0件: --2件: 222, 240
69 Chloroquine 1件: Chloroquine1件: Chloroquine; --3件: 46, 49, 95
70 Cefepime 1件: Cefepime1件: Cefepime; --2件: 60, 299
71 Calfactant 1件: Calfactant1件: Calfactant; --1件: 299
72 Calusterone 1件: Calusterone0件: 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 2
73 Carbaspirin calcium 1件: Carbaspirin calcium1件: Carbasalate calcium; --1件: 46
74 Certolizumab pegol 1件: Certolizumab pegol2件: CERTOLIZUMAB PEGOL; Cimzia; 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬8件: 37, 46, 49, 96, 97, 107, 226, 271
75 Cetuximab 1件: Cetuximab2件: Cetuximab; Erbitux; 1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬2件: 51, 86
76 Cicletanine 1件: Cicletanine1件: Cicletanine; --1件: 86
77 Cifenline 1件: Cibenzoline1件: Cibenzoline; 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 58
78 Cinacalcet 1件: Cinacalcet1件: Cinacalcet; 1件: CASR 💬2件: NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action 💬1件: 238
79 Clemastine 1件: Clemastine2件: Clemastine; CLEMASTINE FUMARATE; 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 13
80 Clodronic acid 1件: Clodronic acid2件: Bonefos; Clasteon; --1件: 274
81 Clofarabine 1件: Clofarabine1件: Clofarabine; 3件: POLA1,
POLA2,
RRM1 💬		7件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬5件: 19, 20, 60, 234, 326
82 Cod liver oil 1件: Cod liver oil1件: Cod liver oil; --1件: 46
83 Corticorelin ovine triflutate 1件: Corticorelin ovine triflutate1件: Acthrel; 2件: CRHR1,
CRHR2 💬		4件: Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 75
84 Creatinine 1件: Creatinine1件: Creatinine; --5件: 2, 46, 60, 70, 222
85 Cyanocobalamin Co 57 1件: Cyanocobalamin2件: Cianocobalamina; Vitamin B12; --5件: 6, 13, 201, 229, 299
86 Cyanocobalamin Co 58 1件: Cyanocobalamin2件: Cianocobalamina; Vitamin B12; --5件: 6, 13, 201, 229, 299
87 Cyanocobalamin Co 60 1件: Cyanocobalamin2件: Cianocobalamina; Vitamin B12; --5件: 6, 13, 201, 229, 299
88 Cysteamine 1件: Cysteamine8件: 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; Cystagon; Cysteamine; Mercaptamina; Mercaptamine; PROCYSBI; --4件: 8, 19, 21, 299
89 Corticorelin 1件: Corticorelin1件: Corticotropin-releasing hormone; 2件: CRHR1,
CRHR2 💬		4件: Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 75
90 Corn starch 1件: Starch, corn1件: Cornstarch; --2件: 90, 257
91 Coconut oil 1件: Coconut oil1件: Coconut oil; --1件: 13
92 Carisbamate 1件: Carisbamate1件: Carisbamate; --1件: 144
93 Carglumic acid 1件: Carglumic acid3件: Carbaglu; Carglumic Acid; N-Carbamylglutamate; 1件: CPS1 💬6件: Alanine, aspartate and glutamate metabolism, Arginine biosynthesis, Biosynthesis of amino acids, Carbon metabolism, Metabolic pathways, Nitrogen metabolism 💬3件: 245, 246, 251
94 Creatinolfosfate 1件: Creatinolfosfate0件: --1件: 13
95 Chlorphenamine 1件: Chlorpheniramine1件: Clorfenamina; 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
96 Caspofungin 1件: Caspofungin2件: Caspofungin; CASPOFUNGIN ACETATE; --1件: 60
97 Cefoperazone 1件: Cefoperazone1件: Cefoperazone; --1件: 296
98 Ceftazidime 1件: Ceftazidime3件: Ceftazidim; Ceftazidima; CEFTAZIDIME; --1件: 299
99 Ceftriaxone 1件: Ceftriaxone1件: CEFTRIAXONE; --4件: 2, 6, 46, 97
100 Celiprolol 1件: Celiprolol1件: Celiprolol; 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 168
101 Cetirizine 1件: Cetirizine3件: Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE; 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 28, 35, 300
102 Cetrorelix 1件: Cetrorelix1件: Cetrorelix; 1件: GNRHR 💬2件: GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 46
103 Cevimeline 1件: Cevimeline1件: Cevimeline; 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬1件: 53
104 Chlorhexidine 1件: Chlorhexidine2件: Chlorhexidine; Chlorhexidine Gluconate; --2件: 86, 299
105 Choline 1件: Choline1件: Choline; --4件: 93, 171, 193, 299
106 Cilastatin 1件: Cilastatin2件: Cilastatin; Cilastatine; 1件: DPEP1 💬-2件: 60, 299
107 Cilazapril 1件: Cilazapril1件: Cilazapril; 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 66
108 Citalopram 1件: Citalopram1件: Citalopram; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
109 Clavulanic acid 1件: Clavulanic acid4件: AMOXICILLIN; Augmentin; Clavulanate; CLAVULANIC ACID; --1件: 299
110 Clenbuterol 1件: Clenbuterol1件: Clenbuterol; 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 1, 2, 6, 13, 256
111 Clobetasol 1件: Clobetasol1件: Clobetasol; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬4件: 39, 46, 51, 162
112 Clomifene 1件: Clomifene2件: Clomiphene; Clomiphene citrate; 2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬1件: 74
113 Clopidogrel 1件: Clopidogrel1件: Clopidogrel; 1件: P2RY12 💬1件: Platelet activation 💬3件: 49, 51, 86
114 Colesevelam 1件: Colesevelam2件: Cholestagel; Colesevelam; --2件: 96, 260
115 Colistin 1件: Colistin1件: COLISTIN; --1件: 299
116 Conivaptan 1件: Conivaptan1件: Conivaptan; 2件: AVPR1A,
AVPR2 💬		5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬1件: 86
117 Cortisone 1件: Cortisone1件: Cortisone; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
118 Cromoglicic acid 1件: Cromoglicic acid4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium; --3件: 2, 85, 98
119 Cyclophosphamide 1件: Cyclophosphamide6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan; --44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
120 Colestipol 1件: Colestipol1件: Colestipol; --1件: 254
121 Carfilzomib 1件: Carfilzomib1件: Carfilzomib; 1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬1件: 28
122 Cediranib 1件: Cediranib1件: Cediranib; 3件: FLT1,
FLT4,
KDR 💬		15件: Breast cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Rheumatoid arthritis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬1件: 34
123 Ceftaroline fosamil 1件: Ceftaroline fosamil1件: Ceftaroline; --1件: 299
124 Cobiprostone 1件: Cobiprostone1件: Cobiprostone; --1件: 46
125 Canakinumab 1件: Canakinumab2件: Canakinumab; ILARIS; 1件: IL1B 💬44件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
126 Carbon monoxide 1件: Carbon monoxide1件: Carbon Monoxide; --4件: 13, 53, 85, 86
127 Crizotinib 1件: Crizotinib1件: Crizotinib; 1件: ALK 💬3件: Non-small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer 💬1件: 34
128 Cenicriviroc 1件: Cenicriviroc1件: Cenicriviroc; 2件: CCR2,
CCR5 💬		11件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬1件: 94
129 Cariprazine 1件: Cariprazine1件: Reagila; 3件: DRD2,
HTR1A,
HTR2A 💬		12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 21
130 Cabozantinib 1件: Cabozantinib1件: Cabozantinib; 3件: AXL,
KDR,
MET 💬		25件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, EGFR tyrosine kinase inhibitor resistance, Epithelial cell signaling in Helicobacter pylori infection, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, Hepatocellular carcinoma, MAPK signaling pathway, Malaria, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Renal cell carcinoma, Transcriptional misregulation in cancer, VEGF signaling pathway 💬1件: 34
131 Ceftolozane 1件: Ceftolozane1件: Ceftolozane; --1件: 299
132 Clazakizumab 1件: Clazakizumab2件: BMS-945429; CLAZAKIZUMAB; --2件: 46, 96
133 Cobimetinib 1件: Cobimetinib1件: Cobimetinib; 2件: MAP2K1,
MAP2K2 💬		89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 280
134 Catridecacog 1件: Catridecacog1件: Catridecacog; --2件: 97, 288
135 Cabotegravir 1件: Cabotegravir1件: Cabotegravir; --1件: 256
136 Censavudine 1件: Censavudine1件: CENSAVUDINE; --2件: 2, 127
137 Cholic acid 1件: Cholic Acid1件: Cholic Acid; 1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 234, 265, 310
138 Calcium carbonate 1件: Calcium carbonate3件: Calcio carbonato; Calcium; Calcium carbonate; --9件: 13, 19, 46, 53, 75, 96, 235, 274, 299
139 Cerliponase alfa 1件: Cerliponase alfa2件: Brineura; Cerliponase Alfa; 1件: TPP1 💬1件: Lysosome 💬1件: 19
140 Clopidogrel hydrochloride 1件: Clopidogrel1件: Clopidogrel; 1件: P2RY12 💬1件: Platelet activation 💬3件: 49, 51, 86
141 Clopidogrel besilate 1件: Clopidogrel1件: Clopidogrel; 1件: P2RY12 💬1件: Platelet activation 💬3件: 49, 51, 86
142 Conestat alfa 1件: Conestat alfa1件: COMPLEMENT C1 ESTERASE INHIBITOR; 3件: C1R,
C1S,
KLKB1 💬		6件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Pertussis, Phagosome, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 61
143 Cannabidiol 1件: Cannabidiol4件: Cannabidiol; Epidiolex; Epidyolex; Sativex; 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
144 Cavosonstat 1件: Cavosonstat1件: Cavosonstat; --1件: 299
145 Cenegermin 1件: Cenegermin3件: Cenegermin; OXERVATE; RhNGF; 1件: NGFR 💬9件: Apoptosis - multiple species, Cytokine-cytokine receptor interaction, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer, Virion - Lyssavirus 💬2件: 53, 90
146 Caplacizumab 1件: Caplacizumab2件: CABLIVI; CAPLACIZUMAB; 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
147 Cenerimod 1件: Cenerimod1件: Cenerimod; 1件: S1PR1 💬3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬1件: 49
148 Cefiderocol 1件: Cefiderocol1件: Cefiderocol; --1件: 299
149 Crovalimab 1件: Crovalimab1件: CROVALIMAB; 1件: C5 💬11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬2件: 62, 109
150 Cipaglucosidase alfa 1件: Cipaglucosidase alfa1件: Cipaglucosidase Alfa; 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
151 Casimersen 1件: Casimersen1件: CASIMERSEN; 1件: DMD 💬4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113
152 COVID-19 vaccine 1件: Janssen COVID-19 Vaccine1件: Covid-19 Vaccine Janssen; --2件: 53, 299
153 Cobitolimod 1件: Cobitolimod1件: COBITOLIMOD; 1件: TLR9 💬9件: African trypanosomiasis, Chagas disease, Herpes simplex virus 1 infection, Malaria, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Salmonella infection, Toll-like receptor signaling pathway, Tuberculosis 💬1件: 97