Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CFTR 3件: Tight junction, Pancreatic secretion, Vibrio cholerae infection D09916 Ivacaftor 1件: 299
2 CFTR 3件: Tight junction, Pancreatic secretion, Vibrio cholerae infection D10134 Lumacaftor 1件: 299
3 CFTR 3件: Tight junction, Pancreatic secretion, Vibrio cholerae infection D11041 Tezacaftor 1件: 299
4 CFTR 3件: Tight junction, Pancreatic secretion, Vibrio cholerae infection D11423 Deutivacaftor 1件: 299
5 CFTR 3件: Tight junction, Pancreatic secretion, Vibrio cholerae infection D11507 Elexacaftor 1件: 299
6 CFTR 3件: Tight junction, Pancreatic secretion, Vibrio cholerae infection D11724 Galicaftor 1件: 299
7 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00113 Atropine 2件: 2, 299
8 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00138 Scopolamine 1件: 2
9 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine 1件: 254
10 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00397 Tropicamide 1件: 6
11 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00465 Oxybutynin 3件: 6, 13, 53
12 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00525 Pilocarpine 3件: 6, 53, 299
13 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00646 Tolterodine 2件: 17, 53
14 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03654 Darifenacin 2件: 6, 13
15 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D07226 Fesoterodine 1件: 6
16 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D07667 Cevimeline 1件: 53
17 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08441 Propiverine 1件: 226
18 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08522 Solifenacin 3件: 6, 13, 53
19 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08638 Trihexyphenidyl 2件: 5, 6
20 CHRM3 5件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine 1件: 156
21 AMY2A 3件: Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion D00216 Acarbose 1件: 298
22 AMY2B 3件: Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion D00216 Acarbose 1件: 298
23 KCNQ1 3件: Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D02910 Amiodarone 2件: 28, 127
24 KCNQ1 3件: Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D09569 Ezogabine 2件: 2, 144
25 ATP1A1 6件: Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin 1件: 299
26 ATP1A1 6件: Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin 3件: 8, 46, 210
27 ATP1A2 6件: Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin 1件: 299
28 ATP1A2 6件: Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin 3件: 8, 46, 210
29 ATP1A3 6件: Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin 1件: 299
30 ATP1A3 6件: Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin 3件: 8, 46, 210
31 ATP1A4 6件: Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin 1件: 299
32 ATP1A4 6件: Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin 3件: 8, 46, 210
33 PRKCB 18件: Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Parathyroid hormone synthesis, secretion and action, Salivary secretion, Pancreatic secretion, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Proteoglycans in cancer D11935 Enzastaurin 1件: 168
34 SLC12A2 3件: Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00247 Bumetanide 2件: 6, 158
35 SLC12A2 3件: Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00331 Furosemide 2件: 6, 86
36 CA2 2件: Proximal tubule bicarbonate reclamation, Pancreatic secretion D00218 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230
37 CA2 2件: Proximal tubule bicarbonate reclamation, Pancreatic secretion D00518 Diclofenamide 1件: 114
38 CA2 2件: Proximal tubule bicarbonate reclamation, Pancreatic secretion D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
39 CA2 2件: Proximal tubule bicarbonate reclamation, Pancreatic secretion D07871 Dorzolamide 1件: 90
40 CD38 2件: Salivary secretion, Pancreatic secretion D10777 Daratumumab 5件: 13, 28, 48, 49, 63
41 CD38 2件: Salivary secretion, Pancreatic secretion D11050 Isatuximab 3件: 28, 61, 283
42 CD38 2件: Salivary secretion, Pancreatic secretion D11945 Mezagitamab 2件: 63, 66