Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Niacinamide [1] Nicotinamide[3] Multivitamin; Niacinamide; Nicotinamide; --[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
2 Calcitriol [1] Calcitriol[1] Calcitriol; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[9] 18, 37, 46, 49, 66, 96, 158, 235, 326
3 Baclofen [1] Baclofen[2] Baclofen; Kemstro; [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[8] 2, 10, 13, 18, 65, 70, 149, 206
4 Methylprednisolone [1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
5 Flumazenil [1] Flumazenil[1] Flumazenil; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206
6 Interferon gamma-1b [1] Interferon gamma-1b[2] ACTIMMUNE; Interferon Gamma-1B; [2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326
7 Riluzole [1] Riluzole[2] Rilutek; Riluzole; [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
8 Lithium carbonate [1] Lithium carbonate[2] Lithium; LITHIUM CARBONATE; --[5] 2, 13, 17, 18, 127
9 Ubidecarenone [1] Ubidecarenone[3] Coenzyme Q-10; Coenzyme Q10; CoQ10; --[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215
10 Idebenone [1] Idebenone[2] Idebenone; Raxone; --[6] 6, 8, 13, 18, 113, 302
11 Artesunate [1] Artesunate[1] Artesunate; --[6] 18, 53, 66, 96, 215, 271
12 Lenograstim [1] Lenograstim[2] G-CSF; Lenograstim; [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65
13 Etravirine [1] Etravirine[3] ETRAVIRINA; Etravirine; INTELENCE; --[1] 18
14 Deferiprone [1] Deferiprone[2] Deferiprone; Ferriprox; --[6] 2, 6, 18, 120, 122, 233
15 Bupropion [1] Bupropion[2] Bupropion; Bupropion Hydrochloride; [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
16 Citalopram [1] Citalopram[1] Citalopram; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
17 Rosuvastatin [1] Rosuvastatin[3] Crestor; Rosuvastatin; Rosuvastatin calcium; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
18 Varenicline [1] Varenicline[2] Champix; VARENICLINE; [2] CHRNA4,
CHRNB2 💬		[4] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[3] 6, 18, 53
19 Vatiquinone [1] Vatiquinone[1] VATIQUINONE; --[2] 18, 21
20 Omaveloxolone [1] Omaveloxolone[1] Omaveloxolone; [1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18