Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Testosterone [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[8] 1, 2, 3, 13, 60, 76, 78, 113
2 Acetaminophen [1] Acetaminophen[4] Acetaminophen; Paracetamol; Tylenol; Ultracet; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
3 Hydroxyurea [1] Hydroxyurea[1] Hydroxyurea; [1] RRM2 💬[7] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284
4 Itraconazole [1] Itraconazole[2] Itraconazole; Sporanox; --[6] 3, 46, 65, 96, 227, 299
5 Valproic acid [1] Valproic acid[3] Valproate; VALPROATE SODIUM; Valproic Acid; [7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
6 Prednisolone [1] Prednisolone[3] Prednisolona; PREDNISOLONE; Prednisolonum; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
7 Midazolam [1] Midazolam[2] Midazolam; Midazolam injection; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
8 Celecoxib [1] Celecoxib[2] Celebrex; Celecoxib; [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
9 Riluzole [1] Riluzole[2] Rilutek; Riluzole; [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
10 Albuterol [1] Salbutamol[3] Albuterol; SALBUTAMOL; Ventolin; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
11 Levocarnitine [1] Levocarnitine[4] Carnitine; L-Carnitine; LEVOCARNITINE; Xyzal; --[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
12 Sesame oil [1] Sesame oil[1] Sesame oil; --[1] 3
13 Dalfampridine [1] Dalfampridine[7] 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra; [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14
14 Amifampridine [1] Amifampridine[2] Amifampridine; Firdapse; [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[3] 3, 11, 12
15 Nusinersen [1] Nusinersen[2] NUSINERSEN; Spinraza; [1] SMN2 💬-[1] 3
16 Olesoxime [1] Olesoxime[1] Olesoxime; --[3] 2, 3, 13
17 Taldefgrobep alfa [1] Talditercept alfa[1] Taldefgrobep alfa; [1] MSTN 💬[1] Cytokine-cytokine receptor interaction 💬[1] 3
18 Reldesemtiv [1] Reldesemtiv[2] CK-2127107; RELDESEMTIV; [1] TNNC2 💬[1] Calcium signaling pathway 💬[2] 2, 3
19 Risdiplam [1] Risdiplam[2] EVRYSDI; Risdiplam; [1] SMN2 💬[1] Nucleocytoplasmic transport 💬[1] 3
20 Onasemnogene abeparvovec [1] Onasemnogene abeparvovec[3] ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma; [1] SMN1 💬-[1] 3
21 Apitegromab [1] Apitegromab[1] Apitegromab; [1] MSTN 💬[1] Cytokine-cytokine receptor interaction 💬[1] 3
22 Branaplam [1] Branaplam[1] Branaplam; [1] SMN2 💬-[2] 3, 8