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e.g. Sirolimus, Adalimumab

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102 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  18f-av-1451  -  -  -  -  [3]  5 ,  7 , 127 💬 
 2  18f-fdg  Fludeoxyglucose (18F)  -  -  -  [12]  5 ,  6 ,  7 , 13, 41, 46, 53, 84, 85, 96, 127, 300 💬 
 3  18f-ro6958948  -  -  -  -  [3]  5 ,  7 , 127 💬 
 4  4-benzyl-2-naphtalen-1-yl-1,2,4-thiadiazolidine-3,5-dione  -  -  -  -  [1]  5  💬 
 5  [18f]florbetapir  -  -  -  -  [1]  5  💬 
 6  [18f]mni-815 (mni-815)  -  -  -  -  [1]  5  💬 
 7  [18f]mni-952  -  -  -  -  [1]  5  💬 
 8  [18f]mni-958  -  -  -  -  [1]  5  💬 
 9  [18f]t807 ([18f]mni-777)  -  -  -  -  [2]  5 ,  6  💬 
 10  [f18]-fddnp  -  -  -  -  [1]  5  💬 
 11  Ab1010  -  -  -  -  [6]  2 ,  5 ,  6 , 13, 46, 96 💬 
 12  Abbv-8e12  -  -  -  -  [2]  5 ,  7  💬 
 13  Al  -  -  -  -  [9]  5 ,  6 ,  7 , 28, 51, 67, 86, 114, 127 💬 
 14  Al-108  -  -  -  -  [1]  5  💬 
 15  Alpha-lipoic acid and l-acetyl carnitine  Levocarnitine  [5] D00048, D00086, D02030, D02176, D04713 💬  -  -  [1]  5  💬 
 16  Anti-parkinson medication  -  -  -  -  [5]  5 ,  6 ,  7 ,  8 , 17 💬 
 17  Antisense oligonucleotide  -  -  -  -  [1]  5  💬 
 18  Ask nr. 21972  -  -  -  -  [1]  5  💬 
 19  Azilect  -  -  -  -  [4]  2 ,  5 ,  6 , 17 💬 
 20  Azp2006 oral solution  -  -  -  -  [1]  5  💬 
 21  Balance  Isoxaflutole  -  -  -  [9]  5 ,  6 , 13, 46, 81, 113, 122, 149, 299 💬 
 22  Bepranemab  -  -  -  -  [1]  5  💬 
 23  Biib092  -  -  -  -  [3]  5 ,  7 , 127 💬 
 24  Bms-986168  Gosuranemab  [1] D11293 💬  [1] MAPT 💬  [4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases  [1]  5  💬 
 25  Bms986168  -  -  -  -  [1]  5  💬 
 26  Botulinum toxin type a  Botulinum toxin type A  [1] D00783 💬  [1] SNAP25 💬  [2] Insulin secretion, Synaptic vesicle cycle  [10]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 70, 113, 149 💬 
 27  Carnitine  Levocarnitine  [3] D02030, D02176, D04713 💬  -  -  [8]  5 , 13, 58, 96, 97, 265, 298, 316 💬 
 28  Coenzym q10 nanodispersion  -  -  -  -  [1]  5  💬 
 29  Coenzym q10, ubiquinon, ubichinon  -  -  -  -  [1]  5  💬 
 30  Coenzyme q10  Ubidecarenone  [1] D01065 💬  -  -  [12]  2 ,  5 ,  6 ,  8 , 10, 18, 46, 57, 113, 193, 214, 215 💬 
 31  Coq10  -  -  -  -  [3]  5 ,  6 ,  8  💬 
 32  Creatine  Creatine  -  -  -  [12]  1 ,  2 ,  5 ,  6 ,  8 , 13, 46, 49, 50, 113, 156, 201 💬 
 33  Datscan  -  -  -  -  [4]  2 ,  5 ,  6 , 17 💬 
 34  Datscan™ ioflupane (123i) injection  -  -  -  -  [3]  5 ,  6 , 17 💬 
 35  Davunetide  Davunetide  [1] D09401 💬  -  -  [3]  5 ,  7 , 127 💬 
 36  Davunetide (al-108, nap)  Davunetide  [1] D09401 💬  -  -  [3]  5 ,  7 , 127 💬 
 37  Device: deep brain stimulation  -  -  -  -  [5]  5 ,  6 ,  7 ,  8 , 17 💬 
 38  Diagnostic test: [18f]-ro6958948  -  -  -  -  [5]  5 ,  6 ,  7 , 17, 127 💬 
 39  Diagnostic test: elecsys (roche) abeta42, ttau and ptau  -  -  -  -  [5]  5 ,  6 ,  7 , 17, 127 💬 
 40  Diagnostic test: flutemetamol f18 injection  Flutemetamol  [1] D10231 💬  -  -  [5]  5 ,  6 ,  7 , 17, 127 💬 
 41  Diagnostic test: lumipulse (fujirebio) abeta42, ttau and ptau  -  -  -  -  [5]  5 ,  6 ,  7 , 17, 127 💬 
 42  Donepezil  Donepezil  [2] D00670, D07869 💬  [1] ACHE 💬  [2] Cholinergic synapse, Glycerophospholipid metabolism  [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬 
 43  Droxidopa  Droxidopa  [1] D01277 💬  [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬  [13] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [3]  5 ,  6 , 17 💬 
 44  Emeramide  Emeramide  -  -  -  [2]  5 , 17 💬 
 45  Exelon 1,5 mg hartkapseln  -  -  -  -  [1]  5  💬 
 46  Exelon 3,0 mg hartkapseln  -  -  -  -  [1]  5  💬 
 47  Exelon 6,0 mg hartkapseln  -  -  -  -  [1]  5  💬 
 48  F-18  -  -  -  -  [2]  5 , 127 💬 
 49  F-18 av 1451  -  -  -  -  [1]  5  💬 
 50  Flortaucipir  Flortaucipir  [1] D11210 💬  -  -  [3]  5 ,  7 , 127 💬 
 51  Flortaucipir f18  Flortaucipir  [1] D11210 💬  -  -  [3]  5 ,  7 , 127 💬 
 52  Flutemetamol  Flutemetamol  -  -  -  [5]  5 ,  6 ,  7 , 17, 127 💬 
 53  Flutemetamol f18  Flutemetamol  [1] D10231 💬  -  -  [5]  5 ,  6 ,  7 , 17, 127 💬 
 54  Fresh frozen plasma  -  -  -  -  [1]  5  💬 
 55  Gdnf & synchro med infusion system  -  -  -  -  [1]  5  💬 
 56  Gold  Gold  -  -  -  [38]  2 ,  5 ,  6 , 13, 17, 34, 46, 49, 50, 53, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 158, 162, 171, 218, 222, 224, 227, 230, 271, 291, 294, 296, 298, 299, 310, 318 💬 
 57  Hydrogen  Hydrogen  -  -  -  [7]  5 ,  6 , 13, 17, 83, 97, 226 💬 
 58  Leucine  Leucine  [1] D00030 💬  -  -  [10]  5 ,  6 ,  7 , 19, 96, 97, 127, 283, 284, 299 💬 
 59  Lipoic acid  Lipoic acid  [2] D00048, D00086 💬  -  -  [5]  2 ,  5 , 13, 14, 20 💬 
 60  Lithium  -  -  -  -  [5]  2 ,  5 ,  6 ,  7 ,  8  💬 
 61  Masitinib  Masitinib  [1] D10229 💬  [1] KIT 💬  [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway  [6]  2 ,  5 ,  6 , 13, 46, 96 💬 
 62  Masitinib 100mg  Masitinib  [1] D10229 💬  [1] KIT 💬  [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway  [2]  2 ,  5  💬 
 63  Masitinib 200mg  Masitinib  [1] D10229 💬  [1] KIT 💬  [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway  [2]  2 ,  5  💬 
 64  Masitinib mesylate  Masitinib  [1] D10229 💬  [1] KIT 💬  [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway  [6]  2 ,  5 ,  6 , 13, 46, 96 💬 
 65  N1,n3-bis(2-mercaptoethyl) isophthalamide  -  -  -  -  [2]  5 , 17 💬 
 66  Nbmi  -  -  -  -  [2]  5 , 17 💬 
 67  Niacinamide  Nicotinamide  [1] D00036 💬  -  -  [4]  5 ,  6 , 13, 67 💬 
 68  Nitrogen  Nitrogen  [1] D00083 💬  -  -  [6]  5 ,  6 , 17, 171, 211, 299 💬 
 69  Np031112  -  -  -  -  [1]  5  💬 
 70  Np031112 600mg  -  -  -  -  [1]  5  💬 
 71  Np031112 800mg  -  -  -  -  [1]  5  💬 
 72  Nt 101  -  -  -  -  [4]  5 ,  6 ,  7 , 17 💬 
 73  Other: 13c6 leucine  Leucine  [1] D00030 💬  -  -  [3]  5 ,  7 , 127 💬 
 74  Placebo  -  -  -  -  [26]  3 ,  5 ,  6 , 13, 14, 37, 40, 46, 49, 50, 51, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬 
 75  Procedure: brain pet scan  -  -  -  -  [3]  5 ,  7 , 127 💬 
 76  Pyruvate, creatine, niacinamide  Creatine  [1] D00036 💬  -  -  [1]  5  💬 
 77  Raclopride  Raclopride  -  -  -  [4]  5 ,  6 ,  7 , 17 💬 
 78  Radiopharmaceuticals  -  -  -  -  [1]  5  💬 
 79  Rasagilin  -  -  -  -  [2]  5 ,  6  💬 
 80  Rasagiline  Rasagiline  [3] D02562, D08469, D10829 💬  [1] MAOB 💬  [14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism  [4]  2 ,  5 ,  6 , 17 💬 
 81  Rasagiline mesilate  Rasagiline  [3] D02562, D08469, D10829 💬  [1] MAOB 💬  [14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism  [3]  2 ,  5 ,  6  💬 
 82  Riluzole  Riluzole  [1] D00775 💬  [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway  [8]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 206 💬 
 83  Rivastigmine  Rivastigmine  [2] D02558, D03822 💬  [1] ACHE 💬  [2] Cholinergic synapse, Glycerophospholipid metabolism  [3]  5 ,  6 , 13 💬 
 84  Salsalate  Salsalate  [1] D00428 💬  [2] PTGS1, PTGS2 💬  [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [1]  5  💬 
 85  Single dose c2n-8e12  -  -  -  -  [1]  5  💬 
 86  Stem cell therapy  -  -  -  -  [1]  5  💬 
 87  Sugar pill  -  -  -  -  [8]  5 ,  6 , 49, 67, 70, 86, 206, 210 💬 
 88  Suvorexant  Suvorexant  [1] D10082 💬  [2] HCRTR1, HCRTR2 💬  [1] Neuroactive ligand-receptor interaction  [3]  5 ,  6 , 13 💬 
 89  Tideglusib  Tideglusib  -  -  -  [2]  5 , 113 💬 
 90  Tolfenamic acid  Tolfenamic acid  [1] D01183 💬  [2] PTGS1, PTGS2 💬  [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [1]  5  💬 
 91  Tpi 287 2 mg/m2  -  -  -  -  [2]  5 ,  7  💬 
 92  Tpi-287 20 mg/m2  -  -  -  -  [2]  5 ,  7  💬 
 93  Tpi-287 6.3 mg/m2  -  -  -  -  [2]  5 ,  7  💬 
 94  Trihexyphenidyl  Trihexyphenidyl  [2] D00787, D08638 💬  [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬  [13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway  [2]  5 ,  6  💬 
 95  Ubidecarenon  -  -  -  -  [1]  5  💬 
 96  Ucb0107 (bepranemab)  -  -  -  -  [1]  5  💬 
 97  Valproic acid  Valproic acid  [1] D00399 💬  [7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬  [17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism  [10]  3 ,  5 , 26, 34, 65, 89, 90, 222, 256, 331 💬 
 98  Vizamyl  -  -  -  -  [3]  5 ,  7 , 127 💬 
 99  Vizamyl (flutemetamol(f-18))  Flutemetamol  -  -  -  [3]  5 ,  7 , 127 💬 
 100  Water  Water  [1] D00001 💬  -  -  [22]  2 ,  5 ,  6 , 13, 17, 19, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299 💬 
 101  Xeomin  -  -  -  -  [7]  5 ,  6 ,  7 , 13, 15, 17, 113 💬 
 102  Zolpidem  Zolpidem  [2] D00706, D08690 💬  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬  [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [3]  5 ,  6 , 46 💬 

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