Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abacavir
(Synonym: Apo-abacavir-lamivudine)		4件: Abacavir; Abacavir sulfate; Triumeq; Ziagen2件: D00891 ,
D07057 		--4件: 2, 135, 265, 325
2 Abiraterone
(Synonym: Apo-abiraterone)		3件: Abiraterone; Abiraterone Acetate; ZYTIGA---2件: 75, 81
3 Acetaminophen
(Synonym: Apo-acetaco #1)		5件: Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
4 Acetylsalicylic acid
(Synonym: Apo-asa Ld)		2件: ACETYLSALICYLIC ACID; Aspirin1件: D00109 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
5 Acyclovir
(Synonym: Apo-acyclovir Ointment)		3件: ACICLOVIR; Acycloguanosine; Acyclovir1件: D00222 --5件: 13, 28, 46, 53, 60
6 Adenosine
(Synonym: Applicell Timeless Ampoule)		2件: Adenosine; Ginseng1件: D00045 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
7 Alendronic acid
(Synonym: Apo-alendronate)		3件: Alendronate; Alendronate sodium; Alendronic acid2件: D00939 ,
D07119 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬7件: 19, 41, 46, 50, 271, 274, 299
8 Alfuzosin
(Synonym: Apo-alfuzosin)		1件: Alfuzosin2件: D01692 ,
D07124 		1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 13
9 Allopurinol
(Synonym: Apo-allopurinol)		2件: Allopurinol; ALLOPURINOL SODIUM1件: D00224 1件: XDH 💬5件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism 💬6件: 6, 46, 57, 66, 96, 97
10 Alprazolam
(Synonym: Apo-alpraz)		1件: Alprazolam1件: D00225 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 8, 75
11 Ambrisentan
(Synonym: Apo-ambrisentan)		3件: Ambrisentan; Letairis; VOLIBRIS1件: D07077 1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬7件: 51, 84, 85, 86, 88, 210, 211
12 Aminopterin
(Synonym: APGA)		1件: Aminopterin---1件: 46
13 Amiodarone
(Synonym: Apo-amiodarone Tablets)		1件: AMIODARONE2件: D00636 ,
D02910 		16件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		32件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 28, 127
14 Amitriptyline
(Synonym: Apo-amitriptyline)		3件: Amitriptylin; Amitriptyline; Amitriptyline hydrochloride2件: D00809 ,
D07448 		2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 78, 97, 226, 299
15 Amlodipine
(Synonym: Apo-amlodipine)		1件: Amlodipine3件: D00615 ,
D02914 ,
D07450 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 13, 51, 67, 298
16 Amoxicillin
(Synonym: Apo-amoxicillin-clavulanate)		4件: Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin3件: D00229 ,
D02925 ,
D07452 		--9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
17 Ampicillin
(Synonym: Apo Ampi Liq 125mg/5ml)		1件: ABPC3件: D00204 ,
D01251 ,
D02119 		--5件: 2, 6, 13, 84, 299
18 Anastrozole
(Synonym: Apo-anastrozole)		2件: Anastrozole; Arimidex1件: D00960 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬3件: 78, 86, 193
19 Apabetalone 1件: Apabetalone1件: D11131 (Name: Apabetalone)4件: BRD2,
BRD3,
BRD4,
BRDT 💬		-1件: 86
20 Apadamtase alfa 1件: Apadamtase alfa---1件: 64
21 Apigenin 1件: Apigenin---1件: 97
22 Apitegromab 1件: Apitegromab1件: D11797 (Name: Apitegromab)1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 3
23 Apixaban 2件: Apixaban; Eliquis1件: D03213 (Name: Apixaban)1件: F10 💬1件: Complement and coagulation cascades 💬3件: 96, 97, 222
24 Aplindore 1件: Aplindore---1件: 6
25 Apomorphine 3件: APOKYN; Apomorfina; Apomorphine2件: D02004 (Name: Apomorphine hydrochloride),
D07460 (Name: Apomorphine)		2件: DRD1,
DRD2 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7
26 Apple 1件: Apple---1件: 70
27 Apraclonidine 1件: Apraclonidine2件: D01008 (Name: Apraclonidine hydrochloride),
D07461 (Name: Apraclonidine)		3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 11
28 Apratastat 1件: Apratastat1件: D08859 (Name: Apratastat)2件: ADAM17,
MMP13 💬		7件: Alzheimer disease, Coronavirus disease - COVID-19, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬1件: 46
29 Apremilast 2件: Apremilast; Otezla1件: D08860 (Name: Apremilast)4件: PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬7件: 46, 50, 56, 97, 107, 162, 271
30 Aprotinin 1件: Aprotinin1件: D02971 (Name: Aprotinin)--1件: 28
31 Aripiprazole
(Synonym: Apo-aripiprazole)		1件: Aripiprazole1件: D01164 4件: DRD2,
DRD3,
HTR1A,
HTR2A 💬		12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 206
32 Ascorbic acid
(Synonym: C-apnto-B6 Vitamins W Magnesium Tab)		4件: Acidum ascorbicum; Ascorbic Acid; Iron; Vitamin C1件: D00018 --8件: 10, 97, 192, 206, 210, 211, 212, 298
33 Atazanavir
(Synonym: Apo-atazanavir)		2件: Atazanavir; Reyataz2件: D01276 ,
D07471 		--1件: 265
34 Atenolol
(Synonym: Apo-atenol Tab 50mg)		1件: ATENOLOL1件: D00235 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 167
35 Atomoxetine
(Synonym: Apo-atomoxetine)		2件: Atomoxetine; Strattera2件: D02574 ,
D07473 		1件: SLC6A2 💬1件: Synaptic vesicle cycle 💬4件: 6, 8, 13, 17
36 Atorvastatin
(Synonym: Apo-amlodipine-atorvastatin)		3件: ATORVASTATIN; Atorvastatin calcium; Lipitor3件: D00258 ,
D00887 ,
D07474 		1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
37 Atovaquone
(Synonym: Apo-atovaquone)		1件: ATOVAQUONE1件: D00236 --1件: 61
38 Azathioprine
(Synonym: Apo-azathioprine)		3件: Azathioprine; Azatioprina; Imuran2件: D00238 ,
D03033 		--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
39 Azithromycin
(Synonym: Apo-azithromycin)		5件: Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX3件: D02134 ,
D06390 ,
D07486 		--6件: 13, 84, 85, 96, 228, 299
40 Baclofen
(Synonym: Apo-baclofen)		2件: Baclofen; Kemstro1件: D00241 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬7件: 2, 10, 13, 18, 65, 149, 206
41 Beclomethasone dipropionate
(Synonym: Apo-beclomethasone Nasal Spray)		2件: BECLOMETASONE DIPROPIONATE; Beclomethasone dipropionate2件: D00689 ,
D07495 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 85, 97, 98
42 Bisacodyl
(Synonym: Apo-bisacodyl)		1件: Bisacodyl1件: D00245 --1件: 13
43 Bisoprolol
(Synonym: Apo-bisoprolol)		2件: Bisoprolol; Bisoprolol Fumarate2件: D00634 ,
D02342 		1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 67, 86, 113
44 Bosentan
(Synonym: Apo-bosentan)		2件: BOSENTAN; TRACLEER2件: D01227 ,
D07538 		2件: EDNRA,
EDNRB 💬		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
45 Brimonidine
(Synonym: Apo-brimonidine)		2件: Brimonidine; Brimonidine Tartrate2件: D02076 ,
D07540 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬2件: 13, 90
46 Bupropion
(Synonym: Aplenzin ER)		2件: Bupropion; Bupropion Hydrochloride3件: D00817 ,
D07591 ,
D07938 (Name: Aplenzin (TN))		2件: SLC6A2,
SLC6A3 💬		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬5件: 8, 18, 21, 96, 171
47 Buspirone
(Synonym: Apo-buspirone)		2件: Buspirone; Buspirone Hydrochloride2件: D00702 ,
D07593 		2件: DRD2,
HTR1A 💬		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬3件: 6, 51, 179
48 Cabergoline
(Synonym: Apo-cabergoline)		3件: CABERGOLINA; Cabergoline; DOSTINEX1件: D00987 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 74, 75
49 Caffeine
(Synonym: Apo-acetaco #1)		1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
50 Calcium carbonate
(Synonym: Apatite Professional)		3件: Calcio carbonato; Calcium; Calcium Carbonate2件: D00932 ,
D10802 		--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299
51 Candesartan cilexetil
(Synonym: Apo-candesartan)		1件: CANDESARTAN2件: D00522 ,
D00626 		1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 67
52 Capecitabine
(Synonym: Apo-capecitabine)		1件: Capecitabine1件: D01223 1件: TYMS 💬4件: Antifolate resistance, Metabolic pathways, One carbon pool by folate, Pyrimidine metabolism 💬1件: 94
53 Capsaicin
(Synonym: Capsaicin No-Fuss Applicator)		2件: Capsaicin; Qutenza1件: D00250 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬5件: 2, 6, 19, 86, 226
54 Captopril
(Synonym: Apo-capto Tab 50mg)		1件: Captopril1件: D00251 (Name: Apopril (TN))1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬8件: 6, 17, 46, 86, 96, 97, 107, 271
55 Carbamazepine
(Synonym: Apo-carbamazepine CR)		1件: Carbamazepine1件: D00252 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬2件: 13, 231
56 Carbidopa
(Synonym: Apo-levocarb - Tab 25mg/250mg)		7件: Carbidopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬9件: 2, 4, 6, 13, 17, 90, 140, 164, 201
57 Carvedilol
(Synonym: Apo-carvedilol)		1件: Carvedilol2件: D00255 ,
D03415 		5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		13件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 57, 86, 113, 210
58 Cefadroxil
(Synonym: Apo-cefadroxil)		0件: 2件: D00257 ,
D02353 		--2件: 222, 240
59 Cefepime
(Synonym: Apo-cefepime)		1件: Cefepime1件: D02376 --2件: 60, 299
60 Cefuroxime
(Synonym: Apo-cefuroxime)		2件: Cefuroxim; Cefuroxime4件: D00262 ,
D00914 ,
D00915 ,
D03431 		--2件: 97, 299
61 Celecoxib
(Synonym: Apo-celecoxib)		2件: CELEBREX; Celecoxib1件: D00567 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
62 Cephalexin
(Synonym: Apo-cephalex)		2件: CEFALEXIN; Cephalexin2件: D00263 ,
D00906 		--1件: 299
63 Cetirizine
(Synonym: Apo-cetirizine)		3件: Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE2件: D00664 ,
D07662 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 28, 35, 300
64 Chlordiazepoxide
(Synonym: Not applicable)		0件: 2件: D00267 ,
D00693 		16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 46
65 Chlorhexidine
(Synonym: Aplicare Antiseptic Chlorhexidine Gluconate)		2件: Chlorhexidine; Chlorhexidine Gluconate4件: D00858 ,
D01345 ,
D03463 ,
D07668 		--2件: 86, 299
66 Chlorpheniramine
(Synonym: Aphedrid Cold and Allergy)		1件: Clorfenamina4件: D00665 ,
D00668 ,
D07398 ,
D07803 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
67 Chlorpromazine
(Synonym: Apo Chlorpromazine)		2件: Chlorpromazine; Chlorpromazine Hydrochloride4件: D00270 ,
D00789 ,
D03274 ,
D04034 		13件: ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬		22件: Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 254
68 Cholecalciferol
(Synonym: Apcal)		5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬25件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
69 Ciclesonide
(Synonym: Apo-ciclesonide)		1件: Ciclesonide1件: D01703 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 84
70 Cilazapril
(Synonym: Apo-cilazapril/hctz)		1件: Cilazapril2件: D01069 ,
D07699 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 66
71 Cimetidine
(Synonym: Apo-cimetidine Oral Solution)		1件: Cimetidine2件: D00295 ,
D03503 		1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 2, 254
72 Cinacalcet
(Synonym: Apo-cinacalcet)		1件: Cinacalcet2件: D03504 ,
D03505 		1件: CASR 💬2件: NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action 💬2件: 85, 238
73 Ciprofloxacin
(Synonym: Apo-ciproflox)		2件: CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE2件: D00186 ,
D02216 		--5件: 2, 60, 96, 97, 299
74 Citalopram
(Synonym: Apo-citalopram)		1件: Citalopram2件: D00822 ,
D07704 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
75 Clarithromycin
(Synonym: Apo-clarithromycin)		1件: CLARITHROMYCIN1件: D00276 --8件: 6, 63, 84, 96, 97, 222, 228, 299
76 Clavulanic acid
(Synonym: Apo-amoxicillin-clavulanate)		4件: AMOXICILLIN; Augmentin; Clavulanate; CLAVULANIC ACID1件: D07711 --1件: 299
77 Clindamycin
(Synonym: Apo-clindamycin)		2件: Clindamycin; Dalacin C phosphate4件: D00277 ,
D01073 ,
D01990 ,
D02132 		--2件: 46, 299
78 Clobazam
(Synonym: Apo-clobazam)		1件: Clobazam1件: D01253 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 140, 144
79 Clobetasol propionate
(Synonym: Cormax Scalp Application)		1件: Clobetasol propionate2件: D01272 ,
D07715 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 46, 162
80 Clonazepam
(Synonym: Apo-clonazepam)		1件: Clonazepam1件: D00280 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6
81 Clonidine
(Synonym: Apo-clonidine)		4件: Clonidin; Clonidina; Clonidine; Clonidine hydrochloride2件: D00281 ,
D00604 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
82 Clopidogrel
(Synonym: Clopidogrel Apotex)		1件: Clopidogrel4件: D00769 ,
D07729 ,
D10823 ,
D10824 		1件: P2RY12 💬1件: Platelet activation 💬2件: 49, 86
83 Colesevelam
(Synonym: Apo-colesevelam)		2件: Cholestagel; Colesevelam2件: D03582 ,
D07743 		--2件: 96, 260
84 Cromoglicic acid
(Synonym: Apo-cromolyn Nasal Spray)		4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium2件: D00526 ,
D07753 		--3件: 2, 85, 98
85 Cyclosporine
(Synonym: Apo-cyclosporine Oral Solution)		10件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
86 D-glucose
(Synonym: SUEROLYTE Oral Electrolyte Solution Apple Flavor)		2件: D-glucose; Glucose1件: D00009 --3件: 49, 86, 88
87 Dabigatran etexilate
(Synonym: Apo-dabigatran)		1件: Dabigatran etexilate1件: D07144 1件: F2 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬1件: 51
88 Dalfampridine
(Synonym: 4-AP)		7件: 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra1件: D04127 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬5件: 3, 4, 6, 13, 14
89 Darifenacin
(Synonym: Apo-darifenacin)		2件: Darifenacin; Emselex2件: D01699 ,
D03654 		1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 6, 13
90 Darunavir
(Synonym: Apo-darunavir)		1件: Darunavir1件: D03656 --1件: 2
91 Dasatinib
(Synonym: Apo-dasatinib)		1件: Dasatinib2件: D03658 ,
D06414 		8件: ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		77件: Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬2件: 51, 85
92 Deferasirox
(Synonym: Apo-deferasirox)		2件: Deferasirox; EXJADE1件: D03669 --3件: 254, 284, 286
93 Desmopressin
(Synonym: Apo-desmopressin)		5件: DDAVP; Desmopressin; Desmopressin Acetate; Desmopressine; Minirin2件: D00291 ,
D02235 		2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬6件: 6, 64, 72, 75, 225, 288
94 Desogestrel
(Synonym: Apri 28 Day)		2件: Desogestrel; Désogestrel1件: D02367 2件: ESR1,
PGR 💬		11件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬1件: 230
95 Dexamethasone
(Synonym: Apo-dexamethasone)		5件: Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
96 Dextromethorphan
(Synonym: AP-Hist DM)		4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta3件: D00848 ,
D03742 ,
D03744 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
97 Diclofenac
(Synonym: Apo-diclofenac)		3件: Diclofenac; Diclofenac sodium; Diclofenac SR3件: D00903 ,
D00904 ,
D07816 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬5件: 13, 34, 46, 78, 271
98 Digoxin
(Synonym: Apo-digoxin)		1件: Digoxin1件: D00298 4件: ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		18件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 8, 46, 210
99 Diltiazem
(Synonym: Apo-diltiaz SR)		2件: Diltiazem; Diltiazem Hydrochloride3件: D00616 ,
D03830 ,
D07845 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 58, 86
100 Dimethyl fumarate
(Synonym: Apo-dimethyl Fumarate)		3件: DIMETHYL FUMARATE; Dimethylfumarat; TECFIDERA1件: D03846 1件: KEAP1 💬6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬5件: 13, 49, 51, 86, 296
101 Diphenhydramine
(Synonym: Aphenap)		2件: Diphenhydramine; Diphenhydramine hydrochloride6件: D00300 ,
D00669 ,
D02419 ,
D03285 ,
D03360 ,
D03854 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
102 Dipivefrin
(Synonym: Apo-dipivefrin)		2件: Dipivefrin; Dipivefrine1件: D02349 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
103 Dipyridamole
(Synonym: Apo-dipyridamole-SC Tab 50mg)		1件: Dipyridamole1件: D00302 2件: PDE4A,
PDE5A 💬		6件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 46, 49, 51, 66, 96, 224
104 Domperidone
(Synonym: Apo-domperidone - Tab 10mg)		1件: Domperidone2件: D01745 ,
D07868 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 13, 17, 51, 230
105 Donepezil
(Synonym: Apo-donepezil)		3件: Aricept; Donepezil; Donepezil hydrochloride2件: D00670 ,
D07869 		1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
106 Dorzolamide
(Synonym: Apo-dorzolamide)		1件: Dorzolamide2件: D00653 ,
D07871 		13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 90
107 Doxazosin
(Synonym: Apo-doxazosin)		2件: CARDURA; DOXAZOSIN2件: D00608 ,
D07874 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 57, 67
108 Doxycycline
(Synonym: Apo-doxycycline Mr)		4件: Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets5件: D00307 ,
D02129 ,
D03903 ,
D03904 ,
D07876 		--16件: 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
109 Duloxetine
(Synonym: Apo-duloxetine)		3件: CYMBALTA; Duloxetine; Duloxetine hydrochloride2件: D01179 ,
D07880 		2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 13
110 Dutasteride
(Synonym: Apo-dutasteride)		2件: Dutasterida; DUTASTERIDE1件: D03820 2件: SRD5A1,
SRD5A2 💬		3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬2件: 1, 2
111 Efavirenz
(Synonym: Apo-efavirenz-emtricitabine-tenofovir)		2件: Efavirenz; SUSTIVA1件: D00896 --1件: 265
112 Emtricitabine
(Synonym: Apo-emtricitabine-tenofovir)		2件: Emtricitabine; TRUVADA1件: D01199 --4件: 25, 93, 265, 325
113 Enalapril
(Synonym: Apo-enalapril Tab 10mg)		2件: Enalapril; Enalapril Maleate2件: D00621 ,
D07892 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬6件: 19, 46, 66, 113, 210, 222
114 Entacapone
(Synonym: Apo-entacapone)		5件: COMTAN; Comtess; ENTACAPONA; ENTACAPONE; Stalevo1件: D00781 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬2件: 6, 17
115 Entecavir
(Synonym: Apo-entecavir)		1件: Entecavir2件: D04008 ,
D07896 		--6件: 46, 56, 96, 97, 107, 271
116 Eplerenone
(Synonym: Apo-eplerenone)		1件: Eplerenone1件: D01115 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬4件: 75, 113, 210, 215
117 Erlotinib
(Synonym: Apo-erlotinib)		1件: Erlotinib2件: D04023 ,
D07907 		1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬1件: 94
118 Escitalopram
(Synonym: Apo-escitalopram)		3件: Citalopram; Escitalopram; Escitalopram oxalate3件: D02567 ,
D07704 ,
D07913 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬3件: 2, 6, 13
119 Esomeprazole
(Synonym: Apo-esomeprazole)		3件: Esomeprazole; Nexium; Omeprazole4件: D01984 ,
D04056 ,
D07917 ,
D09339 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
120 Ethanol
(Synonym: Anti-Bacterial Hand Studly Apple Mr Mom)		3件: Alcohol; Ethanol; Prednisone4件: D00068 ,
D02798 ,
D04855 ,
D06542 		--7件: 13, 51, 58, 97, 279, 280, 298
121 Ethinylestradiol
(Synonym: Apri 28 Day)		3件: Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 7771件: D00554 1件: ESR1 💬9件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬4件: 13, 46, 49, 299
122 Ezetimibe
(Synonym: Apo-ezetimibe)		2件: EZETIMIBE; Ezetrol1件: D01966 1件: NPC1L1 💬1件: Fat digestion and absorption 💬4件: 49, 79, 93, 260
123 Factor IX Complex (Human)
(Synonym: APCC)		1件: Prothrombin Complex Concentrate---1件: 288
124 Famciclovir
(Synonym: Apo-famciclovir)		1件: Famciclovir1件: D00317 --1件: 13
125 Famotidine
(Synonym: Apo-famotidine Injectable)		2件: FAMOTIDINA; Famotidine1件: D00318 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬7件: 6, 46, 61, 86, 98, 107, 300
126 Fenofibrate
(Synonym: Apo-feno-super)		1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬5件: 8, 79, 93, 94, 265
127 Fentanyl
(Synonym: Apo-fentanyl Matrix)		1件: Fentanyl2件: D00320 ,
D01399 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬4件: 46, 70, 215, 231
128 Fesoterodine
(Synonym: Apo-fesoterodine)		1件: Fesoterodine1件: D07226 2件: CHRM2,
CHRM3 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 6
129 Finasteride
(Synonym: Apo-finasteride)		1件: Finasteride1件: D00321 1件: SRD5A2 💬3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬1件: 6
130 Fingolimod
(Synonym: Apo-fingolimod)		2件: Fingolimod; Gilenya1件: D10001 1件: S1PR1 💬3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 13, 14, 156
131 Flavoxate
(Synonym: Apo-flavoxate)		1件: Flavoxate2件: D00718 ,
D07961 		16件: PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		18件: Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 226
132 Flecainide
(Synonym: Apo-flecainide)		3件: Flecainide; FLECAINIDE ACETATE; Flecainidum2件: D00638 ,
D07962 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 6
133 Fluconazole
(Synonym: Apo-fluconazole)		2件: Diflucan; FLUCONAZOLE2件: D00322 ,
D01429 		--2件: 96, 225
134 Fluoxetine
(Synonym: Apo-fluoxetine)		5件: Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC2件: D00326 ,
D00823 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206
135 Fluticasone propionate
(Synonym: Apo-fluticasone)		3件: Flovent; Fluticasone; FLUTICASONE PROPIONATE1件: D01708 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 228
136 Fulvestrant
(Synonym: Apo-fulvestrant)		2件: Faslodex; Fulvestrant1件: D01161 2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 49, 86
137 Furosemide
(Synonym: Apo Furosemide Tab 80mg)		2件: Furosemide; Furosemide Injection1件: D00331 1件: SLC12A2 💬3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬1件: 6
138 Gabapentin
(Synonym: Apo-gabapentin Tablets)		4件: GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298
139 Galantamine
(Synonym: Apo-galantamine)		2件: GALANTAMINE; Galantamine hydrobromide2件: D02173 ,
D04292 		1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬2件: 6, 127
140 Gefitinib
(Synonym: Apo-gefitinib)		1件: Gefitinib1件: D01977 1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬1件: 75
141 Glycerin
(Synonym: Derm-apply)		3件: Bee venom; Glycerine; Glycerol1件: D00028 --6件: 6, 13, 79, 265, 316, 317
142 Haloperidol
(Synonym: Apo-haloperidol Tab 5mg)		1件: Haloperidol2件: D00136 ,
D01898 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 8
143 Hydralazine
(Synonym: Ser-Ap-Es)		1件: Hydralazine2件: D01302 (Name: Apresoline (TN)),
D08044 		1件: AOC3 💬5件: Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism 💬1件: 67
144 Hydrochlorothiazide
(Synonym: Apo Triazide)		2件: Esidrix; HYDROCHLOROTHIAZIDE1件: D00340 1件: SLC12A3 💬-4件: 13, 67, 225, 235
145 Hydrocortisone
(Synonym: Apres Peel Soothing Balm)		6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
146 Hydrogen peroxide
(Synonym: Aplicare Hydrogen Peroxide)		1件: Hydrogen peroxide1件: D00008 --1件: 13
147 Hydromorphone
(Synonym: Apo-hydromorphone CR)		1件: Hydromorphone2件: D00839 ,
D08047 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
148 Hydroxychloroquine
(Synonym: Apo-hydroxyquine)		3件: Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; Plaquenil1件: D08050 --27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
149 Hydroxyurea
(Synonym: Apo-hydroxyurea)		1件: Hydroxyurea1件: D00341 1件: RRM2 💬6件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬8件: 3, 13, 19, 20, 65, 85, 86, 284
150 Ibuprofen
(Synonym: Aprofen Regular Strength)		2件: Ibuprofen; IBUPROFEN 200MG4件: D00126 ,
D01122 ,
D04490 ,
D06606 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299
151 Imatinib
(Synonym: Apo-imatinib)		4件: Gleevec; GLIVEC; Imatinib; Imatinib mesylate2件: D01441 ,
D08066 		3件: ABL1,
KIT,
PDGFRA 💬		32件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
152 Imiquimod
(Synonym: Apo-imiquimod)		1件: Imiquimod1件: D02500 1件: TLR7 💬5件: Coronavirus disease - COVID-19, Influenza A, Measles, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway 💬2件: 34, 51
153 Indapamide
(Synonym: Apo-perindopril-indapamide)		1件: Indapamide2件: D00345 ,
D06401 		1件: SLC12A3 💬-1件: 13
154 Indomethacin
(Synonym: Apo Indomethacin Cap 25mg)		2件: INDOMETACIN; Indomethacin3件: D00141 ,
D01565 ,
D02110 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298
155 Ipratropium
(Synonym: Apo-ipravent Solution - Inh 250mcg/ml)		1件: Ipratropium1件: D02212 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 6, 86
156 Irbesartan
(Synonym: Apo-irbesartan)		2件: Aprovel; IRBESARTAN1件: D00523 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 66, 167, 168, 222
157 Ketoconazole
(Synonym: Apo-ketoconazole)		2件: KETOCONAZOLE; NIZORAL1件: D00351 1件: CYP17A1 💬6件: Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬3件: 8, 13, 75
158 Ketorolac
(Synonym: Apo-ketorolac Injectable)		2件: Ketorolac; Ketorolac Tromethamine2件: D00813 ,
D08104 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬2件: 70, 226
159 Lacosamide
(Synonym: Apo-lacosamide)		1件: Lacosamide1件: D07299 2件: SCN3A,
SCN9A 💬		1件: Taste transduction 💬3件: 2, 46, 149
160 Lactulose
(Synonym: Apo-lactulose)		1件: Lactulose1件: D00352 --3件: 13, 96, 291
161 Lamivudine
(Synonym: Apo-zidovudine-lamivudine-nevirapine)		4件: COMBIVIR; Epivir; Lamivudine; Triumeq1件: D00353 --7件: 2, 26, 42, 46, 135, 265, 325
162 Lamotrigine
(Synonym: Apo-lamotrigine)		2件: Lamictal; Lamotrigine1件: D00354 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬5件: 13, 34, 38, 114, 144
163 Lansoprazole
(Synonym: Apo-lansoprazole)		1件: Lansoprazole1件: D00355 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299
164 Leflunomide
(Synonym: Apo-leflunomide)		3件: ARAVA; Leflunomide; Leflunomidum1件: D00749 1件: DHODH 💬3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
165 Lenalidomide
(Synonym: Apo-lenalidomide)		2件: Lenalidomide; REVLIMID1件: D04687 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬8件: 16, 26, 28, 34, 49, 284, 300, 331
166 Letrozole
(Synonym: Apo-letrozole)		1件: Letrozole1件: D00964 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬2件: 81, 89
167 Levetiracetam
(Synonym: Apo-levetiracetam)		2件: KEPPRA; Levetiracetam1件: D00709 1件: SV2A 💬1件: ECM-receptor interaction 💬5件: 2, 4, 6, 13, 307
168 Levodopa
(Synonym: Apo-levocarb-tab 25mg/100mg)		8件: DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬8件: 2, 4, 6, 17, 90, 140, 164, 201
169 Levofloxacin
(Synonym: Apo-levofloxacin)		2件: Levaquin; Levofloxacin2件: D00588 ,
D08120 		--5件: 46, 53, 84, 85, 299
170 Lidocaine
(Synonym: Apicaine-X)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine3件: D00358 ,
D02086 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
171 Linezolid
(Synonym: Apo-linezolid)		1件: LINEZOLID1件: D00947 --1件: 299
172 Lisinopril
(Synonym: Apo-lisinopril Tablet 20 mg)		2件: Lisinopril; Zestril2件: D00362 ,
D08131 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222
173 Lithium carbonate
(Synonym: Apo-lithium Carbonate)		2件: Lithium; Lithium Carbonate1件: D00801 --6件: 2, 13, 17, 18, 19, 127
174 Loperamide
(Synonym: Apo-loperamide)		2件: LOPERAMIDE; Loperamide hydrochloride3件: D00729 ,
D07113 ,
D08144 		3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 13, 97
175 Loratadine
(Synonym: Apo-loratadine)		2件: Loratadina; LORATADINE1件: D00364 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 46, 89, 98
176 Lorazepam
(Synonym: Apo-lorazepam Tab 2mg)		1件: Lorazepam1件: D00365 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 36, 231
177 Losartan
(Synonym: Apo-losartan/hctz)		3件: Cozaar; Losartan; LOSARTAN POTASSIUM2件: D00357 ,
D08146 		1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
178 Magnesium oxide
(Synonym: C-apnto-B6 Vitamins W Magnesium Tab)		1件: Magnesium oxide1件: D01167 --3件: 6, 166, 291
179 Medroxyprogesterone acetate
(Synonym: Apo-medroxy Tablets)		1件: Medroxyprogesterone2件: D00951 ,
D08166 		1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬6件: 13, 35, 46, 49, 51, 60
180 Megestrol acetate
(Synonym: Apo-megestrol)		1件: Megestrol acetate2件: D00952 ,
D08167 		1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 76
181 Meloxicam
(Synonym: Apo-meloxicam)		1件: Meloxicam1件: D00969 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 46, 49, 271, 296
182 Memantine
(Synonym: Apo-memantine)		3件: EBIXA; Memantine; MEMANTINE HYDROCHLORIDE2件: D04905 ,
D08174 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬7件: 2, 6, 8, 13, 49, 127, 205
183 Mesalazine
(Synonym: Apriso)		10件: 5-Aminosalicylic acid; 5-ASA; ASACOL; Mesalamine; MESALAZINA; MESALAZINE; Mesalazinum; MEZAVANT; Pentasa; Salofalk1件: D00377 (Name: Apriso (TN))--4件: 46, 96, 97, 164
184 Metformin
(Synonym: Appformin)		5件: Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine2件: D00944 ,
D04966 		2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
185 Methimazole
(Synonym: Apo-methimazole)		1件: Methimazole1件: D00401 1件: TPO 💬4件: Autoimmune thyroid disease, Metabolic pathways, Thyroid hormone synthesis, Tyrosine metabolism 💬1件: 50
186 Methotrexate
(Synonym: Apo-methotrexate)		6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; METOTREXATO; Méthotrexate2件: D00142 ,
D02115 		2件: DHFR,
DHFR2 💬		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
187 Methyldopa
(Synonym: Apo Methazide 15)		1件: Methyldopa2件: D00405 ,
D08205 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 323
188 Methylphenidate
(Synonym: Apo-methylphenidate)		3件: Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin2件: D01296 (Name: APTENSIO XR),
D04999 		2件: SLC6A2,
SLC6A3 💬		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 6, 13, 34, 84, 113, 179, 206
189 Metoclopramide
(Synonym: Apo-metoclop Tab 5mg)		1件: METOCLOPRAMIDE3件: D00726 ,
D02213 ,
D05008 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 51
190 Metoprolol
(Synonym: Apo-metoprolol)		2件: Metoprolol; METOPROLOL SUCCINATE3件: D00601 ,
D02358 ,
D05011 		1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226
191 Metronidazole
(Synonym: Apo-metronidazole)		3件: Flagyl; Metronidazol; Metronidazole3件: D00409 ,
D05016 ,
D05017 		--8件: 46, 51, 63, 94, 95, 96, 97, 291
192 Midazolam
(Synonym: Apo-midazolam Injectable 5 mg/ml)		2件: Midazolam; Midazolam injection3件: D00550 ,
D00696 ,
D05028 		16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
193 Midodrine
(Synonym: Apo-midodrine)		2件: Midodrine; MIDODRINE HYDROCHLORIDE2件: D01307 ,
D08220 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬3件: 6, 17, 58
194 Milrinone
(Synonym: Apo-milrinone Injectable)		1件: Milrinone2件: D00417 ,
D02085 		2件: PDE3A,
PDE3B 💬		11件: Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 294
195 Mineral oil
(Synonym: Apj Hemorrhoidal)		1件: Paraffin Oil1件: D05042 --1件: 291
196 Minoxidil
(Synonym: Apo-gain Liq 20mg/ml)		1件: MINOXIDIL1件: D00418 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬1件: 179
197 Modafinil
(Synonym: Apo-modafinil)		2件: Modafinil; Provigil1件: D01832 --5件: 6, 13, 49, 93, 113
198 Mometasone furoate
(Synonym: Apo-mometasone)		3件: Mometasone; Mometasone furoate; Nasonex1件: D00690 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 162
199 Montelukast
(Synonym: Apo-montelukast Sodium Chewable)		3件: Montelukast; MONTELUKAST SODIUM; Singulair2件: D00529 ,
D08229 		1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228
200 Moxifloxacin
(Synonym: Apo-moxifloxacin)		2件: Moxifloxacin; Moxifloxacin Hydrochloride2件: D00874 ,
D08237 		--9件: 2, 6, 46, 49, 85, 86, 113, 240, 299
201 Mycophenolate mofetil
(Synonym: Apo-mycophenolate Mofetil)		3件: CellCept; Mycophenolate Mofetil; Mycophenolate mofetil TEVA3件: D00752 ,
D05094 ,
D05095 		2件: IMPDH1,
IMPDH2 💬		3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
202 Mycophenolic acid
(Synonym: Apo-mycophenolic Acid)		5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic Acid; Myfortic1件: D05096 2件: IMPDH1,
IMPDH2 💬		3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
203 Nabilone
(Synonym: Apo-nabilone)		1件: NABILONE1件: D05099 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬2件: 6, 13
204 Nadolol
(Synonym: Apo-nadolol)		1件: Nadolol1件: D00432 2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
205 Naltrexone
(Synonym: Apo-naltrexone)		2件: Naltrexone; Naltrexone hydrochloride2件: D02095 ,
D05113 		3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
206 Naproxen
(Synonym: Apo-napro-NA)		5件: Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid1件: D00118 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 107, 271
207 Nebivolol
(Synonym: Apo-nebivolol)		1件: Nebivolol1件: D05127 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 17, 85, 113, 167
208 Neomycin
(Synonym: Antibiotic Application)		1件: Neomycin1件: D08260 --3件: 96, 97, 296
209 Nevirapine
(Synonym: Apo-nevirapine)		1件: Nevirapine1件: D00435 --1件: 265
210 Nicotinamide
(Synonym: Aplin Spot Remover)		4件: Ginseng; Multivitamin; Niacinamide; Nicotinamide1件: D00036 --11件: 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
211 Nifedipine
(Synonym: Apo-nifed Pa)		1件: Nifedipine1件: D00437 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 50, 81
212 Nitroglycerin
(Synonym: Apo-nitroglycerin)		2件: Nitroglycerin; Nitroglycerine1件: D00515 --2件: 46, 51
213 Nortriptyline
(Synonym: Apo-nortriptyline - Cap 25mg)		2件: Nortriptyline; Nortriptyline hydrochloride2件: D00816 ,
D08288 		2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 226
214 Olanzapine
(Synonym: Apo-olanzapine)		2件: Olanzapine; Zyprexa2件: D00454 ,
D06623 		11件: ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 8
215 Olive oil
(Synonym: Rhodd Ato Repair Body So Ap)		1件: Olive Oil1件: D03311 --3件: 13, 49, 53
216 Omeprazole
(Synonym: Apo-omeprazole)		5件: Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM4件: D00455 ,
D01207 ,
D05259 ,
D05261 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
217 Ondansetron
(Synonym: Apo-ondansetron)		1件: Ondansetron2件: D00456 ,
D00678 		5件: HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		2件: Serotonergic synapse, Taste transduction 💬4件: 6, 97, 107, 231
218 Oxcarbazepine
(Synonym: Apo-oxcarbazepine)		2件: Oxcarbazepine; Trileptal1件: D00533 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 13
219 Oxybutynin
(Synonym: Apo-oxybutynin)		1件: Oxybutynin2件: D00465 ,
D00722 		5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 13, 53
220 Oxycodone
(Synonym: Apo-oxycodone/acet)		3件: OXYCODONE; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen3件: D03783 ,
D05312 ,
D05462 		3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬7件: 6, 13, 46, 70, 226, 231, 298
221 Paclitaxel
(Synonym: Apo-paclitaxel Injectable)		1件: Paclitaxel2件: D00491 ,
D05333 		9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬2件: 46, 85
222 Pantoprazole
(Synonym: Apo-pantoprazole)		1件: PANTOPRAZOLE2件: D02593 ,
D05353 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 13, 65
223 Paroxetine
(Synonym: Apo-paroxetine)		1件: Paroxetine4件: D02260 ,
D02362 ,
D05374 ,
D05375 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 6, 13, 46, 85
224 Pectin
(Synonym: SMITH BROS WARM APPLE PIE WITH CINNAMON FLAVOR Warming Throat)		1件: Pectin1件: D02316 --1件: 96
225 Pegfilgrastim
(Synonym: pegfilgrastim-apgf)		1件: Pegfilgrastim1件: D06889 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬1件: 60
226 Perindopril
(Synonym: Apo-perindopril/amlodipine)		2件: Coversyl; Perindopril2件: D00624 ,
D03753 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222
227 Petrolatum
(Synonym: Chapstick Moisturizer Green Apple)		1件: Petrolatum1件: D05331 --3件: 35, 158, 162
228 Phenoxymethylpenicillin
(Synonym: Apo Pen Vk)		0件: 3件: D00497 ,
D02506 ,
D05411 		--3件: 13, 97, 215
229 Phenylephrine
(Synonym: Aphedrid Cold and Allergy)		1件: Phenylephrine2件: D00511 ,
D08365 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
230 Pioglitazone
(Synonym: Apo-pioglitazone)		1件: Pioglitazone2件: D00945 ,
D08378 		1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
231 Piperazine 1件: Piperazine6件: D00807 ,
D01393 ,
D02127 ,
D02145 (Name: Camin AP (TN)),
D05486 ,
D06224 		--2件: 58, 272
232 Posaconazole
(Synonym: Apo-posaconazole)		2件: Noxafil; Posaconazole1件: D02555 --4件: 60, 65, 96, 299
233 Pramipexole
(Synonym: Apo-pramipexole)		7件: Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL2件: D00559 ,
D05575 		3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20
234 Pravastatin
(Synonym: Apo-pravastatin)		2件: Pravastatin; Pravastatin sodium2件: D00893 ,
D08410 		1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 13, 46, 49, 67, 79, 96, 164, 265, 333
235 Prednisone
(Synonym: Apo Prednisone Tab 50mg)		3件: PREDNISONA; Prednisone; RAYOS1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
236 Pregabalin
(Synonym: Apo-pregabalin Capsules)		2件: Lyrica; Pregabalin1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬5件: 13, 36, 46, 70, 298
237 Propranolol
(Synonym: Apo-propranolol)		3件: Propanolol; Propranolol; Propranolol Hydrochloride2件: D00483 ,
D08443 		3件: ADRB1,
ADRB2,
ADRB3 💬		12件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬7件: 6, 158, 167, 215, 227, 278, 296
238 Prucalopride
(Synonym: Apo-prucalopride)		2件: Prucalopride; Resolor1件: D09205 1件: HTR4 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway 💬3件: 13, 51, 96
239 Pseudoephedrine
(Synonym: Aprodine)		1件: Pseudoephedrine4件: D00485 ,
D05648 ,
D05649 ,
D08449 		9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
240 Pyridoxine
(Synonym: C-apnto-B6 Vitamins W Magnesium Tab)		2件: PYRIDOXINE; Vitamin B62件: D02179 ,
D08454 		--5件: 6, 93, 145, 206, 320
241 Quetiapine
(Synonym: Apo-quetiapine)		2件: Quetiapine; Seroquel2件: D00458 ,
D08456 		2件: DRD2,
HTR2A 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬2件: 6, 13
242 Quinapril
(Synonym: Apo-quinapril)		1件: Accuretic2件: D00459 ,
D03752 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 19
243 Quinidine
(Synonym: Apo Quinidine Tab 200mg)		4件: Nuedexta; Quinidina; Quinidine; Quinidine Sulfate4件: D00642 ,
D00643 ,
D02272 ,
D08458 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 2, 8, 13
244 Rabeprazole
(Synonym: Apo-rabeprazole)		1件: Rabeprazole2件: D00724 ,
D08463 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 2, 51
245 Raloxifene
(Synonym: Apo-raloxifene)		2件: Raloxifene; Raloxifene hydrochloride2件: D02217 ,
D08465 		2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬1件: 46
246 Ramipril
(Synonym: Apo-ramipril)		1件: Ramipril1件: D00421 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 46, 49, 66, 67, 113, 218, 257
247 Ranitidine
(Synonym: Apo-ranitidine Tablet 300mg)		1件: Ranitidine2件: D00422 ,
D00673 		1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 13, 65
248 Rasagiline
(Synonym: Apo-rasagiline)		4件: Azilect; Rasagilina; Rasagiline; RASAGILINE MESYLATE3件: D02562 ,
D08469 ,
D10829 		1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 2, 5, 6, 13, 17, 58, 66
249 Repaglinide
(Synonym: Apo-repaglinide)		1件: Repaglinide1件: D00594 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬3件: 6, 21, 299
250 Riboflavin
(Synonym: Appedrine)		2件: Riboflavin; Vitamin B23件: D00050 ,
D01622 ,
D01913 		--8件: 13, 38, 46, 96, 97, 162, 168, 265
251 Riluzole
(Synonym: Apo-riluzole)		2件: Rilutek; Riluzole1件: D00775 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
252 Risedronic acid
(Synonym: Apo-risedronate)		3件: Risedronate; Risedronate sodium; Risedronic acid3件: D00942 ,
D03234 ,
D08484 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 46, 50, 66, 93, 95, 96, 107, 113, 274
253 Risperidone
(Synonym: Apo-risperidone)		1件: Risperidone1件: D00426 2件: DRD2,
HTR2A 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬5件: 8, 156, 179, 187, 206
254 Rivastigmine
(Synonym: Apo-rivastigmine)		3件: Exelon; Rivastigmine; Rivastigmine Transdermal System2件: D02558 ,
D03822 		1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬3件: 5, 6, 13
255 Ropinirole
(Synonym: Apo-ropinirole)		3件: REQUIP; Ropinirole; Ropinirole Hydrochloride2件: D00784 ,
D08489 		3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 2, 6, 74, 309
256 Rosuvastatin
(Synonym: Apo-rosuvastatin)		3件: Crestor; Rosuvastatin; Rosuvastatin calcium2件: D01915 ,
D08492 		1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
257 Royal jelly
(Synonym: Apis Mellifera Secretion)		1件: Royal jelly1件: D09754 --1件: 49
258 Salbutamol
(Synonym: Apo-salvent Aem 100mcg)		3件: Albuterol; Salbutamol; Ventolin1件: D02147 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬14件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299
259 Salicylic acid
(Synonym: Walgreens Apricot Scrub Acne Treatment)		2件: 2-Hydroxybenzoic acid; Salicylic acid1件: D00097 --1件: 97
260 Saxagliptin
(Synonym: Apo-saxagliptin)		1件: Saxagliptin1件: D08996 1件: DPP4 💬1件: Protein digestion and absorption 💬1件: 299
261 Sertraline
(Synonym: Apo-sertraline)		1件: Sertraline2件: D00825 ,
D02360 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206
262 Sildenafil
(Synonym: Apo-sildenafil R)		6件: Mysildecard; Revatio; Sildenafil; Sildenafil Citrate; SILDENAFILO; Viagra2件: D02229 ,
D08514 (Name: Aphrodil (TN))		1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
263 Silodosin
(Synonym: Apo-silodosin)		2件: Silodosin; Silodyx1件: D01965 1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 6, 13
264 Simvastatin
(Synonym: Apo-simvastatin)		3件: Simvastatin; Simvastatina; Simvastatine1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
265 Sodium bicarbonate
(Synonym: Not Applicable)		1件: Sodium Bicarbonate1件: D01203 --1件: 299
266 Sodium chloride
(Synonym: SUEROLYTE Oral Electrolyte Solution Apple Flavor)		6件: Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium Chloride; SPORANOX1件: D02056 --21件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
267 Sodium fluoride
(Synonym: Darby Apf Bubble Gum)		2件: Beam; Sodium fluoride1件: D00943 --1件: 51
268 Solifenacin
(Synonym: Apo-solifenacin)		2件: Solifenacin; Solifenacin Succinate2件: D01269 ,
D08522 		1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬3件: 6, 13, 53
269 Spironolactone
(Synonym: Apo-spirozide Tab)		1件: Spironolactone1件: D00443 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬7件: 58, 67, 86, 113, 210, 218, 225
270 Sucralfate
(Synonym: Apo-sucralfate - Tab 1g)		1件: Sucralfate1件: D00446 --1件: 98
271 Sulfamethoxazole
(Synonym: Apo Sulfamethoxazole Tab 500mg)		3件: Bactrim; Sulfamethoxazole; Sulphamethoxazole1件: D00447 --5件: 44, 49, 61, 85, 299
272 Sulfasalazine
(Synonym: Apo Sulfasalazine Tab 500mg)		3件: Salazosulfapyridine; Salicylazosulfapyridine; Sulfasalazine1件: D00448 --6件: 46, 86, 94, 107, 270, 271
273 Sulindac
(Synonym: Apo-sulin Tab 200mg)		1件: Sulindac1件: D00120 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 206
274 Tacrolimus
(Synonym: Apo-tacrolimus)		2件: Prograf; TACROLIMUS2件: D00107 ,
D08556 		5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
275 Tadalafil
(Synonym: Apo-tadalafil Pah)		4件: Adcirca; CIALIS; Tadalafil; TADALAFILO1件: D02008 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210
276 Tamoxifen
(Synonym: Apo-tamox Tab 10mg)		2件: Tamoxifen; TAMOXIFEN CITRATE2件: D00966 ,
D08559 		2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬4件: 2, 86, 113, 227
277 Telmisartan
(Synonym: Apo-telmisartan/hctz)		1件: Telmisartan1件: D00627 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 67
278 Temozolomide
(Synonym: Apo-temozolomide)		1件: Temozolomide1件: D06067 --1件: 34
279 Tenofovir disoproxil
(Synonym: Apo-efavirenz-emtricitabine-tenofovir)		4件: Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA1件: D01982 --2件: 93, 265
280 Terazosin
(Synonym: Apo-terazosin)		1件: Terazosin2件: D00610 ,
D08569 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6
281 Terbinafine
(Synonym: Apo-terbinafine)		1件: Terbinafine2件: D02219 ,
D02375 		--3件: 96, 97, 271
282 Teriparatide
(Synonym: Apo-teriparatide Injection)		4件: Forsteo; Forteo; PTH 1-34; Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬7件: 46, 65, 68, 70, 71, 235, 274
283 Tetrabenazine
(Synonym: Apo-tetrabenazine)		2件: Tetrabenazine; Xenazine1件: D08575 1件: SLC18A2 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 8
284 Tetracycline
(Synonym: APT T3X Tetracycline Hydrochloride First Aid Antibiotic)		2件: Tetracyclin; Tetracycline1件: D00201 --5件: 13, 36, 46, 53, 97
285 Theophylline
(Synonym: Apo-theo ER)		1件: Theophylline5件: D00371 ,
D01712 ,
D02017 ,
D06103 ,
D06104 		19件: ADORA1,
ADORA2A,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		24件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 236, 299
286 Thiamine
(Synonym: Appedrine)		2件: THIAMINE; Vitamin B11件: D08580 --5件: 8, 13, 93, 145, 265
287 Ticagrelor
(Synonym: Apo-ticagrelor)		1件: Ticagrelor1件: D09017 1件: P2RY12 💬1件: Platelet activation 💬3件: 36, 46, 85
288 Timolol
(Synonym: Apo-timop)		2件: Timolol; TIMOLOL MALEATE3件: D00378 ,
D00603 ,
D08600 		2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 157, 227
289 Tipranavir
(Synonym: Aptivus)		1件: Tipranavir2件: D03843 ,
D08605 (Name: Aptivus (TN))		--1件: 265
290 Tobramycin
(Synonym: Apo-tobramycin)		9件: Bethkis; TOBI; TOBI PODHALER; TOBRAMICINA; TOBRAMYCIN; Tobramycin inhalation solution; TOBRAMYCIN SULFATE; Tobramycine; Tobramycinum2件: D00063 ,
D02542 		--1件: 299
291 Tolterodine
(Synonym: Apo-tolterodine)		1件: Tolterodine2件: D00646 ,
D01148 		1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 17, 53
292 Topiramate
(Synonym: Apo-topiramate)		2件: TOPAMAX; Topiramate1件: D00537 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193
293 Tramadol
(Synonym: Apo-tramadol/acet)		2件: Tramadol; Ultracet2件: D01355 ,
D08623 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271
294 Trazodone
(Synonym: Apo-trazodone Tablets 50mg)		1件: Trazodone2件: D00820 ,
D08626 		4件: HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 2
295 Triamcinolone
(Synonym: Apo-triamcinolone AQ)		4件: Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide5件: D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
296 Trifluoperazine 1件: Trifluoperazine3件: D00799 ,
D01448 ,
D08636 (Name: Apo-trifluoperazine (TN))		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284
297 Trihexyphenidyl
(Synonym: Aparkane Tab 2mg)		1件: Trihexyphenidyl2件: D00787 ,
D08638 (Name: Apo-trihex (TN))		5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6
298 Trimethoprim
(Synonym: Apo-sulfatrim Oral Suspension)		2件: Bactrim; Trimethoprim2件: D00145 ,
D06236 		--8件: 36, 44, 49, 60, 61, 85, 298, 299
299 Tryptophan
(Synonym: Apo-tryptophan)		2件: Propanoic acid; Tryptophan1件: D00020 --2件: 6, 75
300 Tyrosine
(Synonym: Appbutamone)		4件: Alanine; L-Tyrosine; Propanoic acid; Tyrosine1件: D00022 --5件: 6, 75, 86, 111, 298
301 Urea
(Synonym: Not Applicable)		1件: Urea2件: D00023 ,
D01749 		--2件: 72, 251
302 Valaciclovir
(Synonym: Apo-valacyclovir)		1件: Valacyclovir3件: D00398 ,
D08664 ,
D10518 		--1件: 65
303 Valganciclovir
(Synonym: Apo-valganciclovir)		1件: Valganciclovir1件: D02495 --6件: 28, 60, 85, 97, 299, 331
304 Valproic acid
(Synonym: Apo-divalproex)		3件: Valproate; VALPROATE SODIUM; Valproic Acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
305 Valsartan
(Synonym: Apo-valsartan/hctz)		3件: Diovan; Entresto; Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 218, 222, 224
306 Vardenafil
(Synonym: Apo-vardenafil)		3件: Levitra; Vardenafil; Vardenafilo3件: D02731 ,
D03260 ,
D08668 		1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬3件: 13, 86, 299
307 Varenicline
(Synonym: Apo-varenicline)		2件: Champix; Varenicline1件: D08669 2件: CHRNA4,
CHRNB2 💬		4件: Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬2件: 6, 18
308 Venlafaxine
(Synonym: Apo-venlafaxine XR)		2件: Venlafaxine; VENLAFAXINE HYDROCHLORIDE2件: D00821 ,
D08670 		2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬3件: 6, 13, 46
309 Verapamil
(Synonym: Apo-verap SR)		2件: VERAPAMIL; Verapamil SR2件: D00619 ,
D02356 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 96, 140, 167
310 Vitamin A
(Synonym: Appedrine)		1件: Vitamin A2件: D00069 ,
D06543 		2件: RARA,
RARB 💬		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 13, 53, 90
311 Vitamin D
(Synonym: Appedrine)		3件: Calciferol; Cod liver oil; Vitamin D---24件: 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299
312 Voriconazole
(Synonym: Apo-voriconazole)		2件: Vfend; VORICONAZOLE1件: D00578 --2件: 60, 299
313 Warfarin
(Synonym: Apo-warfarin)		2件: Warfarin; Warfarin Sodium3件: D00564 ,
D01280 ,
D08682 		2件: NQO1,
VKORC1 💬		7件: Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬13件: 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
314 Zidovudine
(Synonym: Apo-lamivudine-zidovudine)		3件: COMBIVIR; Retrovir; Zidovudine1件: D00413 --7件: 25, 26, 94, 135, 265, 325, 331
315 Zinc
(Synonym: SUEROLYTE Oral Electrolyte Solution Apple Flavor)		3件: Nicotinamide; Wilzin; Zinc---4件: 2, 113, 171, 299
316 Zolmitriptan
(Synonym: Apo-zolmitriptan)		1件: Zolmitriptan1件: D00415 2件: HTR1B,
HTR1D 💬		4件: Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 6
317 Zolpidem
(Synonym: Apo-zolpidem ODT)		2件: Zolpidem; Zolpidem Tartrate2件: D00706 ,
D08690 		16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 5, 6, 46
318 Zopiclone
(Synonym: Apo-zopiclone)		1件: Zopiclone1件: D01372 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6