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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
10.15mg KPG-818 dose----[1] 49
20.6mg KPG-818 dose----[1] 49
31 mg/kg CNTO 136----[1] 49
410 mg/kg CNTO 136----[1] 49
52-deoxy-2 [F-18] fluoro-2-d-glucose[2] D-glucose,
Dextrose, unspecified form		[1] D00009 --[1] 49
62mg KPG-818 dose----[1] 49
74 mg/kg CNTO 136----[1] 49
881mg aspirin[1] Acetylsalicylic acid[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 49
9A-623----[1] 49
10Abatacept[1] Abatacept[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
11Abatacept also known as Orencia also known as CTLA4-Ig[1] Abatacept[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[1] 49
12ABBV-105----[2] 46, 49
13Abetimus[1] Abetimus---[1] 49
14ABETIMUS SODIUM[1] Abetimus---[1] 49
15Abetimus sodium (LJP 394)[1] Abetimus---[1] 49
16ABR-215757----[2] 49, 51
17ABT-199----[1] 49
18ABT-494----[7] 41, 46, 49, 96, 97, 107, 271
19AC0058TA----[1] 49
20Acazicolcept----[1] 49
21Acetaminophen[1] Acetaminophen[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[16] 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
22Acetaminophen/paracetamol[1] Acetaminophen[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 35, 49
23Acetate[1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
24Acetylcysteine[1] Acetylcysteine[1] D00221 --[20] 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
25Acido Micofenolico[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 49
26ACM----[1] 49
27ACT-334441----[1] 49
28Acthar[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[9] 2, 13, 14, 46, 49, 50, 66, 84, 222
29Acthar Gel[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 13, 46, 49, 50, 84, 222
30Acthar high dose (80 U)[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 49
31Acthar low dose (40 U)[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 49
32Ad26.COV2.S----[5] 13, 35, 46, 49, 51
33Administration of Methylprednisolone + Prednisone + Mycophenolate mofetil[4] Methylprednisolone,
Mycophenolate mofetil,
Mycophenolic acid,
Prednisone		[11] D00407 ,
D00473 ,
D00751 ,
D00752 ,
D00979 ,
D05000 ,
D05001 ,
D05002 ,
D05094 ,
D05095 ,
D05096 		[3] IMPDH1,
IMPDH2,
NR3C1 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Purine metabolism 💬[1] 49
34Administration of methylprednisolone, paracetamol and dexchlorpheniramine[3] Acetaminophen,
Dexchlorpheniramine,
Methylprednisolone		[8] D00217 ,
D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 ,
D07803 		[4] HRH1,
NR3C1,
PTGS1,
PTGS2 💬		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Calcium signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 49
35AGS-009----[1] 49
36AIDSVAX® B/E----[1] 49
37AKBM-3031----[1] 49
38ALDESLEUCHINA----[1] 49
39ALDESLEUKIN[1] Aldesleukin[1] D00748 [3] IL2RA,
IL2RB,
IL2RG 💬		[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[4] 49, 65, 96, 97
40Alfacalcidol[1] Alfacalcidol[1] D01518 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[8] 41, 46, 49, 50, 96, 107, 235, 238
41ALITRETINOIN[1] Alitretinoin[1] D02815 [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		[19] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 49
42Allogeneic bone marrow transplant----[1] 49
43ALLOGENEIC MESENCHYMAL STROMAL CELLS DERIVED FROM THE UMBILICAL CORD[1] Human Umbilical Cord Mesenchymal Stem Cells---[1] 49
44Allogeneic MSC (AlloMSC)----[1] 49
45Allogeneic stem cell transplantation----[5] 19, 20, 49, 62, 84
46Alpha-tocopherol[2] Tocopherol,
Vitamin E		[2] D02331 ,
D02332 		--[2] 49, 206
47ALPN-101----[1] 49
48ALX-0061----[2] 46, 49
49ALX-0061 150 mg/mL----[1] 49
50AMG 557----[1] 49
51AMG 570----[2] 46, 49
52AMG 592----[3] 46, 49, 97
53AMG 623----[1] 49
54AMG 811----[1] 49
55AMG592----[2] 46, 49
56AMG811----[1] 49
57Anakinra[1] Anakinra[1] D02934 [2] IL1R1,
IL1R2 💬		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[17] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 84, 86, 97, 106, 107, 299
58ANIFROLUMAB[1] Anifrolumab[1] D11082 [2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[2] 46, 49
59Anifrolumab 1000 mg[1] Anifrolumab[1] D11082 [2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 49
60Anifrolumab 300 mg[1] Anifrolumab[1] D11082 [2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 49
61Anti BAFF (B cell activating factor)----[1] 49
62Anti LP40 antibody, subclass IgG4----[1] 49
63Anti LP40 anticuerpo, subclase IgG4----[1] 49
64Anti-blood dendritic cell antigen 2----[1] 49
65Anti-CD19-CAR-T cells----[1] 49
66Anti-CD20 B cell depletion with Truxima[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 49
67Anti-CD28dAb----[3] 49, 53, 160
68Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody----[1] 49
69Anti-pandemic H1N1 influenza vaccine----[6] 46, 49, 50, 51, 53, 107
70Anti-Thymocyte Globulin----[18] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285
71ASF-1096 Cream 0.25%----[1] 49
72ASF-1096 Cream 0.5%----[1] 49
73ASF-1096 Cream 1.0%----[1] 49
74Aspirin[1] Acetylsalicylic acid[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[12] 13, 22, 34, 46, 49, 51, 58, 86, 113, 158, 210, 231
75Aspirin and meloxicam[2] Acetylsalicylic acid,
Meloxicam		[2] D00109 ,
D00969 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 49
76Assigned Interventions CD19/BCMA CAR T-cells----[3] 49, 51, 53
77Atacicept[1] Atacicept[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[4] 13, 46, 49, 66
78Atacicept 150 mg[1] Atacicept[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 13, 49
79Atacicept 75 mg[1] Atacicept[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[3] 13, 49, 66
80Atacicept 75 milligram (mg)[1] Atacicept[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
81Atorvastatin[1] Atorvastatin[3] D00258 ,
D00887 ,
D07474 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
82Autologous CD34+HPC transplantation (HSCT)----[1] 49
83Autologous EBV specific CTL infusion----[1] 49
84Autologous Hematopoietic Stem Cell Transplantation----[7] 11, 13, 14, 28, 49, 51, 84
85Autologous peripheral blood stem cell transplantation----[8] 28, 40, 41, 42, 45, 46, 49, 283
86Aviptadil[1] Aviptadil[1] D12127 --[5] 49, 51, 84, 85, 86
87Azathioprine[1] Azathioprine[2] D00238 ,
D03033 		--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
88BAL----[5] 49, 51, 84, 85, 299
89Baricinitib----[1] 49
90Baricitinib[1] Baricitinib[1] D10308 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
91Behavioral: heart health educational program----[1] 49
92Behavioral: Questionnaires----[2] 28, 49
93BELIMUMAB[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300
94Belimumab 1 mg/kg[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 46, 49
95Belimumab 10 mg/kg[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[3] 43, 46, 49
96Belimumab 10 mg/kg plus standard therapy[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
97Belimumab 100 mg SC[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
98Belimumab 10mg/kg[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
99Belimumab 200 mg SC[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
100Belimumab 200 mg/mL[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
101Belimumab 4 mg/kg[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 46, 49
102Belimumab autoinjector[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
103Belimumab for IV[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
104Belimumab for SC[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
105Belimumab Injection[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
106Belimumab Injection [Benlysta][1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
107Belimumab or benlysta[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
108Belimumab plus Early Vaccination[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
109Belimumab plus Late Vaccination[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
110Benazepril[1] Benazepril[2] D00620 ,
D07499 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 49, 57, 218, 224
111Benazepril Pill[1] Benazepril[2] D00620 ,
D07499 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 49
112Benlysta[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[5] 43, 49, 53, 66, 222
113Benlysta (belimumab)[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[4] 11, 49, 53, 222
114Benlysta 400 mg powder for concentrate for solution for infusion[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 43, 49
115Benlysta 400 mg powder for concentrate for solution for infusions[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
116BENLYSTA? (belimumab)[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
117Benlysta®[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 49, 222
118BENLYSTA™ (belimumab)[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
119BI 705564----[1] 49
120BIIB059----[1] 49
121Blisibimod[1] Blisibimod[1] D10311 --[5] 43, 44, 49, 63, 66
122Blood sample----[18] 8, 13, 46, 49, 51, 53, 61, 65, 66, 84, 96, 97, 107, 127, 235, 274, 288, 299
123BMS-188667----[9] 46, 49, 53, 65, 96, 97, 107, 222, 271
124BMS-931699[1] Lulizumab pegol---[3] 49, 53, 160
125BMS-986165----[3] 49, 96, 97
126BMS-986165 Capsule----[1] 49
127BMS-986165 Tablet----[1] 49
128BMS-986195[1] Branebrutinib[1] D11478 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 46, 49, 53
129BMS-986256[1] Afimetoran[1] D11908 --[1] 49
130BMS-986256 (Oral)[1] Afimetoran[1] D11908 --[1] 49
131BMS-986256-06, TLR7/8 Antagonist[1] Afimetoran[1] D11908 --[1] 49
132BMS986195----[3] 46, 49, 53
133BNT162b2----[5] 13, 35, 46, 49, 51
134Bone densitometry----[2] 49, 162
135BORTEZOMIB[1] Bortezomib[1] D03150 [1] PSMB5 💬[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331
136BOS161721----[1] 49
137BR-DIM----[1] 49
138Branebrutinib[1] Branebrutinib[1] D11478 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 46, 49, 53
139Brentuximab[1] Brentuximab vedotin[1] D09587 [10] TNFRSF8,
TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[11] Alzheimer disease, Amyotrophic lateral sclerosis, Cytokine-cytokine receptor interaction, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[2] 49, 51
140Brentuximab vedotin[1] Brentuximab vedotin[1] D09587 [10] TNFRSF8,
TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[11] Alzheimer disease, Amyotrophic lateral sclerosis, Cytokine-cytokine receptor interaction, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[2] 49, 51
141Brepocitinib----[1] 49
142Bronchoalveolar lavage (BAL fluid)----[3] 49, 51, 85
143BT063----[1] 49
144Busulfan[1] Busulfan[1] D00248 --[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326
145Calciferol[1] Vitamin D---[1] 49
146Calcitriol[1] Calcitriol[1] D00129 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[9] 18, 37, 46, 49, 66, 96, 158, 235, 326
147Calcium[1] Calcium---[30] 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
148Campath[1] Alemtuzumab[1] D02802 [1] CD52 💬-[12] 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326
149CC----[14] 13, 28, 46, 49, 51, 56, 84, 85, 96, 97, 98, 162, 202, 271
150CC-220[1] CC-220---[2] 49, 84
151CD34+ Peripheral Blood Stem Cell Reinfusion----[1] 49
152CDP3194----[1] 49
153CDP7657----[1] 49
154CELLCEPT----[5] 11, 13, 42, 43, 49
155Cenerimod[1] Cenerimod[1] D11283 [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 49
156Cenerimod 0.5 mg[1] Cenerimod[1] D11283 [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 49
157Cenerimod 1 mg[1] Cenerimod[1] D11283 [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 49
158Cenerimod 2 mg[1] Cenerimod[1] D11283 [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 49
159Cenerimod 4 mg[1] Cenerimod[1] D11283 [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 49
160CEP-33457----[1] 49
161Certolizumab----[5] 46, 49, 96, 270, 271
162Certolizumab Pegol[1] Certolizumab pegol[1] D03441 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 37, 46, 49, 96, 97, 107, 226, 271
163Cervarix[1] Human papillomavirus type 16 L1 capsid protein antigen---[3] 49, 50, 107
164Cervarix suspensie voor injectie[1] Human papillomavirus type 16 L1 capsid protein antigen---[3] 49, 50, 107
165CFZ533----[4] 11, 46, 49, 53
166Chloroquine[1] Chloroquine[3] D02125 ,
D02366 ,
D03469 		--[3] 46, 49, 95
167CHOLECALCIFEROL[1] Cholecalciferol[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[10] 13, 19, 34, 46, 49, 75, 96, 97, 298, 299
168Cholecalciferol and C. Xanthorrhiza[1] Cholecalciferol[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 49
169Ciclosporin[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[13] 26, 46, 49, 50, 53, 55, 60, 61, 97, 222, 226, 228, 269
170CICLOSPORINA[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[4] 49, 60, 97, 228
171CIMZIA[1] Certolizumab pegol[1] D03441 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[5] 46, 49, 96, 97, 271
172Clofarabine[1] Clofarabine[1] D03546 [3] POLA1,
POLA2,
RRM1 💬		[6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[9] 19, 20, 40, 46, 49, 60, 96, 234, 326
173Clopidogrel[1] Clopidogrel[4] D00769 ,
D07729 ,
D10823 ,
D10824 		[1] P2RY12 💬[1] Platelet activation 💬[2] 49, 86
174CNTO1275----[6] 46, 49, 84, 93, 96, 97
175Collection of samples----[4] 49, 65, 95, 107
176Combination Product: Belimumab[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
177Computed Tomography----[5] 34, 40, 46, 49, 96
178Conjugated equine estrogens[1] Conjugated estrogens[2] D04070 ,
D05987 		--[1] 49
179Conjugated equine estrogens 0.625 mg/d + MPA 5 mg/d/10d[1] Conjugated estrogens[2] D04070 ,
D05987 		--[1] 49
180Continuation of azathioprine[1] Azathioprine[2] D00238 ,
D03033 		--[1] 49
181Corn starch[1] Starch, corn[1] D05297 --[1] 49
182Corticosteroids----[10] 41, 46, 49, 64, 97, 107, 164, 220, 296, 300
183Corticosteroids (prednisone or prednisolone)[2] Prednisolone,
Prednisone		[9] D00472 ,
D00473 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 49
184COVID-19 vaccine----[3] 46, 49, 51
185Creatine[1] Creatine---[16] 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 113, 156, 201, 256
186Crestor[1] Rosuvastatin[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 49, 79, 299
187CS20AT04 (allogenic bone marrow derived mesenchymal stem cell)----[1] 49
188CsA----[8] 19, 49, 50, 53, 60, 63, 222, 228
189CSM allogéniques issues de cordons ombilicaux ( MTI-PP)----[1] 49
190CTLA4-IgG4m (RG2077)----[1] 49
191CTLA4Ig----[4] 46, 49, 96, 271
192Cumulative corticosteroid exposure----[1] 49
193Curcumin[1] Curcumin---[11] 2, 13, 46, 49, 67, 74, 94, 96, 97, 139, 299
194Curcumin supplement[1] Curcumin---[1] 49
195Cyclophosphamide[1] Cyclophosphamide[2] D00287 ,
D07760 		--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
196Cyclophosphamide-prednisone-azathioprine[3] Azathioprine,
Cyclophosphamide,
Prednisone		[5] D00238 ,
D00287 ,
D00473 ,
D03033 ,
D07760 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 49
197Cyclosporin[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[17] 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326
198Cyclosporin A[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[11] 46, 49, 53, 56, 60, 62, 63, 93, 95, 113, 164
199Cyclosporine[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
200Cyclosporine A[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[11] 19, 20, 36, 49, 50, 53, 58, 60, 107, 234, 283
201CYMBALTA----[3] 6, 13, 49
202Cytarabine[1] Cytarabine[3] D00168 ,
D03046 ,
D03637 		--[7] 11, 13, 14, 25, 49, 60, 65
203D-glucose[2] D-glucose,
Dextrose, unspecified form		[1] D00009 --[3] 49, 86, 88
204Dapagliflozin[1] Dapagliflozin[1] D08897 [1] SLC5A2 💬-[2] 49, 222
205DAPIROLIZUMAB PEGOL[1] Dapirolizumab pegol---[2] 13, 49
206Dapirolizumab pegol (DZP)[1] Dapirolizumab pegol---[1] 49
207Daratumumab[1] Daratumumab[1] D10777 [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[5] 16, 28, 49, 63, 222
208Daratumumab Injection[1] Daratumumab[1] D10777 [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[2] 16, 49
209Darzalex[1] Daratumumab[1] D10777 [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[2] 28, 49
210Dehydroepiandrosterone[1] Prasterone[1] D08409 [3] AR,
ESR1,
ESR2 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 49, 53, 83, 96, 113
211Dehydroepiandrosterone (DHEA)[1] Prasterone[1] D08409 [3] AR,
ESR1,
ESR2 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 49
212DELTACORTENE*20CPR 5MG----[3] 49, 97, 113
213Depletion of CD3/CD19 in an autologous stem cell transplant----[2] 49, 51
214Dexchlorpheniramine[1] Dexchlorpheniramine[1] D07803 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[2] 13, 49
215DHA----[8] 6, 46, 48, 49, 94, 113, 299, 301
216DHEA[1] Prasterone[1] D08409 [3] AR,
ESR1,
ESR2 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[3] 49, 86, 96
217Dihydroartemisinin[1] Artenimol[1] D07362 --[1] 49
218Dihydroartemisinin tablet[1] Artenimol[1] D07362 --[1] 49
219Dimethylfumarat[1] Dimethyl fumarate[1] D03846 [1] KEAP1 💬[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[1] 49
220Diphenhydramine[1] Diphenhydramine[6] D00300 ,
D00669 ,
D02419 ,
D03285 ,
D03360 ,
D03854 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
221Diphenhydramine hydrochloride[1] Diphenhydramine[6] D00300 ,
D00669 ,
D02419 ,
D03285 ,
D03360 ,
D03854 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[2] 11, 49
222Dipyridamole[1] Dipyridamole[1] D00302 [2] PDE4A,
PDE5A 💬		[6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 46, 49, 51, 66, 96, 224
223Docosahexaenoic acid[1] Doconexent---[7] 6, 49, 90, 94, 240, 299, 301
224Doppler ultrasound----[1] 49
225Drug inducing arthritis, lupus, hepatitis, or capillary leak syndrom----[2] 46, 49
226DS-7011a----[1] 49
227DZP----[1] 49
228E6742----[1] 49
229Edratide[1] Edratide[1] D03957 --[1] 49
230Edratide Acetate[2] Acetate,
Edratide		[1] D03957 --[1] 49
231EFAVALEUKIN ALFA[1] Efavaleukin alfa[1] D11612 --[2] 49, 97
232Eicosapentaenoic acid[1] Icosapent[1] D08061 --[6] 49, 96, 97, 296, 297, 338
233ELSUBRUTINIB----[1] 49
234Emapalumab[1] Emapalumab[1] D11120 [1] IFNG 💬[32] African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[2] 49, 107
235Enteric-Coated Mycophenolate Sodium[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 49
236EPA----[6] 8, 46, 48, 49, 113, 301
237EPA and DHA supplementation----[2] 48, 49
238Epatuzumab----[1] 49
239EPRATUZUMAB[1] Epratuzumab[1] D04036 [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
240Epratuzumab 100 mg[1] Epratuzumab[1] D04036 [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
241Epratuzumab 1200 mg[1] Epratuzumab[1] D04036 [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
242Epratuzumab 400 mg[1] Epratuzumab[1] D04036 [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
243Epratuzumab 600 mg[1] Epratuzumab[1] D04036 [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
244Epratuzumab iv[1] Epratuzumab[1] D04036 [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
245Epratuzumab sc[1] Epratuzumab[1] D04036 [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
246ERL080A----[1] 49
247Estradiol[1] Estradiol[8] D00105 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299
248Ethinyl estradiol[2] Estradiol,
Ethinylestradiol		[9] D00105 ,
D00554 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[3] 46, 49, 299
249Ethylhydrogenfumarat, Calciumsalz----[1] 49
250Ethylhydrogenfumarat, Magnesiumsalz----[1] 49
251Ethylhydrogenfumarat, Zinksalz----[1] 49
252EVOBRUTINIB[1] Evobrutinib---[3] 13, 46, 49
253Extended release dipyridamole 200mg/aspirin 25mg[2] Acetylsalicylic acid,
Dipyridamole		[2] D00109 ,
D00302 		[4] PDE4A,
PDE5A,
PTGS1,
PTGS2 💬		[28] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Purine metabolism, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 49
254Ezetimibe[1] Ezetimibe[1] D01966 [1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260
255Ezetimibe+Simvastatin Drug Combination[2] Ezetimibe,
Simvastatin		[2] D00434 ,
D01966 		[2] HMGCR,
NPC1L1 💬		[5] AMPK signaling pathway, Bile secretion, Fat digestion and absorption, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 49
256Fan beam CT scan----[1] 49
257Faslodex[1] Fulvestrant[1] D01161 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 49
258Filgrastim[1] Filgrastim[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[28] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331
259Fish Oil[1] Fish oil---[7] 13, 46, 49, 66, 96, 260, 299
260Flash glucose monitoring system[1] Dextrose, unspecified form---[1] 49
261Flow-mediated dilation of the brachial artery----[1] 49
262Fludarabine[1] Fludarabine[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[18] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
263Fludarabine phosphate[2] Fludarabine,
Phosphate ion		[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[12] 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286
264Fluzone[1] Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated)---[2] 21, 49
265Focetria (Monovalent MF59-Adjuvanted vaccine)----[3] 46, 49, 271
266Folate[1] Folic acid[1] D00070 --[4] 13, 41, 46, 49
267FolateScan (Technetium Tc 99mEC20)----[4] 13, 46, 49, 96
268Folic acid[1] Folic acid[1] D00070 --[4] 6, 46, 49, 84
269Forigerimod[1] Forigerimod[1] D09904 --[1] 49
270Fostamatinib[1] Fostamatinib[1] D09347 [1] SYK 💬[17] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[4] 46, 49, 61, 66
271Fostamatinib Disodium (R935788)[1] Fostamatinib[1] D09347 [1] SYK 💬[17] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[2] 46, 49
272Fumaderm----[1] 49
273Fumaderm®----[1] 49
274Fumaderm® initial----[1] 49
275Fusion[1] Iron polymaltose---[7] 11, 13, 46, 49, 69, 70, 271
276G-CSF[1] Filgrastim[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[16] 2, 6, 11, 13, 16, 47, 49, 51, 60, 62, 65, 85, 96, 284, 285, 331
277Gardasil[1] Human papillomavirus type 6 L1 capsid protein antigen---[1] 49
278Gazyvaro[1] Obinutuzumab[1] D09321 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[2] 49, 222
279GC+HCQ----[1] 49
280GDC-0853----[3] 13, 46, 49
281GDC-0853 RO7010939----[3] 13, 46, 49
282Genetic: Polymorphism Analysis----[2] 49, 60
283GL701----[1] 49
284GLPG3970 film-coated tablet----[1] 49
285Glucose[1] Dextrose, unspecified form---[15] 2, 6, 13, 49, 50, 65, 75, 86, 88, 96, 160, 195, 254, 257, 299
286Gold[1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
287Group A SLE prospective study----[1] 49
288Growth colony stimulating factor (G-CSF)[1] Filgrastim[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[1] 49
289GSK1550188----[4] 11, 49, 66, 222
290GSK1550188 1mg/kg or 10mg/kg----[1] 49
291GSK1550188 IV----[1] 49
292GSK1550188 SC----[1] 49
293GSK2586184----[1] 49
294GSK2586184 100 mg----[1] 49
295GSK2586184 200 mg----[1] 49
296GSK2586184 400 mg----[1] 49
297GSK2586184 50 mg----[1] 49
298GSK2586184 800mg single and repeat dose----[1] 49
299GSK2586184 new formulation----[1] 49
300GSK2586184 standard formulation----[1] 49
301H.P. Acthar Gel[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 46, 49, 50, 84, 222
302HA 1A ANTICORPO MONOCLONALE UMANO CLASSE IGM----[2] 6, 49
303HB-adMSCs[1] Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins---[7] 2, 4, 6, 13, 46, 49, 113
304HCQ----[2] 46, 49
305Hematopoietic Stem Cell Transplantation----[13] 11, 13, 14, 19, 20, 35, 46, 49, 51, 65, 96, 234, 285
306HGS1006----[1] 49
307HGS1006, LymphoStat-B, monoclonal anti-BLyS, LSB, BENLYSTA[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 49, 53
308High Dietary Sodium----[1] 49
309High Dose Mesenchymal Stem Cells (MSCs)----[1] 49
310Hiomega-3 supplement of Naturalis® company -----[1] 49
311HLL2----[1] 49
312HLL2 (Epratuzumab)[1] Epratuzumab[1] D04036 [1] CD22 💬[3] B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 49
313HLL2 (trivial name or chemical description)----[1] 49
314HLL2,IMMU-103----[1] 49
315HPV prophylactic vaccine Gardasil[1] Human papillomavirus type 6 L1 capsid protein antigen---[1] 49
316HrIL-2 active----[3] 46, 49, 53
317Human papillomavirus vaccination (Gardasil)[1] Human papillomavirus type 6 L1 capsid protein antigen---[1] 49
318Human umbilical cord derived MSC transplantation for SLE----[1] 49
319Humanised IgG1 monoclonal antibody against blood dendritic cell antigen 2----[1] 49
320Hydroxychloroquine[1] Hydroxychloroquine[1] D08050 --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
321Hydroxychloroquine (Z0188)[1] Hydroxychloroquine[1] D08050 --[1] 49
322Hydroxychloroquine or Chloroquine[2] Chloroquine,
Hydroxychloroquine		[4] D02125 ,
D02366 ,
D03469 ,
D08050 		--[1] 49
323Hydroxychloroquine reduced[1] Hydroxychloroquine[1] D08050 --[1] 49
324Ianalumab[1] Ianalumab[1] D12151 [1] TNFRSF13C 💬[5] Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬[5] 35, 46, 49, 53, 95
325Ibandronate[1] Ibandronate[1] D08056 [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[2] 46, 49
326Ibandronate+alfacalcidol+calcium[3] Alfacalcidol,
Calcium,
Ibandronate		[2] D01518 ,
D08056 		[2] FDPS,
VDR 💬		[9] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Terpenoid backbone biosynthesis, Tuberculosis 💬[1] 49
327ICI 182,780 (Faslodex)[1] Fulvestrant[1] D01161 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 49
328ICP-022----[2] 46, 49
329IFN-a 2b Kinoid Drug Substance----[1] 49
330IFN-a2b Kinoid----[1] 49
331IFN-K----[2] 49, 50
332IFN-Kinoid----[2] 49, 50
333IFN-Kinoid Drug Substance----[2] 49, 50
334IFNa-Kinoid----[2] 49, 50
335IL-2[1] Human interleukin-2---[7] 2, 46, 49, 53, 56, 96, 107
336IL-6R nanobody----[1] 49
337ILT-101[1] Aldesleukin[1] D00748 [3] IL2RA,
IL2RB,
IL2RG 💬		[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[1] 49
338IMMU-103----[1] 49
339Immune ablation and hematopoietic stem cell support.----[1] 49
340IMMUNOGLOBULIN G----[8] 2, 11, 13, 14, 49, 50, 63, 65
341Immunoglobulin G1, anti-(human type I interferon receptor) (human monoclonal MEDI-546 heavy chain), disulfide with human monoclonal MEDI-546-chain, dimer----[1] 49
342Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate)[4] Azathioprine,
Methotrexate,
Mycophenolate mofetil,
Mycophenolic acid		[8] D00142 ,
D00238 ,
D00752 ,
D02115 ,
D03033 ,
D05094 ,
D05095 ,
D05096 		[4] DHFR,
DHFR2,
IMPDH1,
IMPDH2 💬		[7] Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism 💬[1] 49
343Individualized dose of rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 49
344Infliximab[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[26] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
345Influenz virus surface antigens----[1] 49
346INFLUENZA VACCINE (SURFACE ANTIGEN, INACTIVATED)----[1] 49
347Influvac[1] Haemagglutinin-strain B---[3] 46, 49, 50
348INTERLEUKIN 2----[9] 46, 49, 51, 56, 63, 95, 96, 97, 271
349INTERLEUKIN-2[1] Human interleukin-2---[8] 2, 35, 49, 55, 65, 96, 97, 162
350Intravenous Immunoglobulin----[8] 13, 14, 35, 38, 39, 49, 51, 309
351IPP - 201101----[1] 49
352IPP-201101----[1] 49
353IPP-201101, P140----[1] 49
354IS (B cell depletion therapy)----[5] 13, 35, 46, 49, 51
355IS (MMF or MPA)----[5] 13, 35, 46, 49, 51
356IS (MTX)----[5] 13, 35, 46, 49, 51
357Iscalimab[1] Iscalimab[1] D11610 [1] CD40 💬[17] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬[2] 49, 53
358Itolizumab[1] Itolizumab---[1] 49
359Itolizumab [Bmab 600][1] Itolizumab---[1] 49
360JBT-101----[4] 49, 50, 51, 299
361JNJ-54767414----[2] 28, 49
362JNJ-55920839----[1] 49
363JNJ-56022473----[1] 49
364JNJ-80202135----[4] 11, 46, 49, 53
365Kineret[1] Anakinra[1] D02934 [2] IL1R1,
IL1R2 💬		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[9] 28, 41, 46, 49, 65, 106, 107, 266, 299
366KPG-818----[1] 49
367KZR-616[1] KZR-616---[3] 49, 50, 61
368L04AA26----[1] 49
369LA294----[1] 49
370LABP-104 250mg----[1] 49
371LAQUINIMOD[1] Laquinimod---[4] 8, 13, 49, 96
372Leflunomide[1] Leflunomide[1] D00749 [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
373Lenalidomide[1] Lenalidomide[1] D04687 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 16, 26, 28, 34, 49, 284, 300, 331
374Leukapheresis----[5] 49, 51, 96, 284, 285
375Levothyroxine[1] Levothyroxine[2] D01010 ,
D08125 		[2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[3] 49, 78, 80
376Lisinopril[1] Lisinopril[2] D00362 ,
D08131 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
377Lisinopril Pills[1] Lisinopril[2] D00362 ,
D08131 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 49
378LJP 394----[1] 49
379LJP394----[1] 49
380Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol)[4] Acetate,
Estradiol,
Ethinylestradiol,
Norethisterone		[11] D00105 ,
D00182 ,
D00554 ,
D00953 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[3] ESR1,
ESR2,
PGR 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 46, 49
381Low Dietary Sodium----[1] 49
382Low Dose Mesenchymal Stem Cells (MSCs)----[1] 49
383Low-dose Aldesleukin (Proleukin®)[1] Aldesleukin[1] D00748 [3] IL2RA,
IL2RB,
IL2RG 💬		[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[1] 49
384Lulizumab Pegol[1] Lulizumab pegol---[1] 49
385Lupuzor----[1] 49
386LY2127399----[3] 13, 46, 49
387LY3009104----[6] 46, 49, 50, 93, 107, 325
388LY3361237----[1] 49
389LY3471851----[2] 49, 97
390LymphoStat-B----[1] 49
391LymphoStat-B TM----[1] 49
392LymphoStat-B®, monoclonal anti-BLyS, LSB, BENLYSTA®[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
393M281----[5] 11, 46, 49, 53, 61
394M2951----[3] 13, 46, 49
395M2951 (Other Name: Evobrutinib)[1] Evobrutinib---[1] 49
396M5049----[1] 49
397M5049 high dose----[1] 49
398M5049 low dose----[1] 49
399M5049 medium dose----[1] 49
400MabThera[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[22] 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271
401MabThera (Rituximab)[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[4] 13, 46, 49, 53
402MEDI 545----[1] 49
403MEDI-545----[2] 49, 50
404MEDI-545 600----[1] 49
405MEDI-546----[2] 49, 51
406MEDI-570 0.03 MG----[1] 49
407MEDI-570 0.1 MG----[1] 49
408MEDI-570 0.3 MG----[1] 49
409MEDI-570 1 MG----[1] 49
410Medroxyprogesterone----[1] 49
411Melatonin[1] Melatonin[1] D08170 [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202
412Meloxicam[1] Meloxicam[1] D00969 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 46, 49, 271, 296
413Memantine[1] Memantine[2] D04905 ,
D08174 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 6, 8, 13, 49, 127, 205
414Mesenchymal stem cells----[11] 2, 6, 13, 20, 49, 51, 60, 96, 222, 274, 299
415Mesenchymal Stromal Cells[1] Human Umbilical Cord Mesenchymal Stem Cells---[10] 2, 36, 49, 51, 60, 96, 97, 107, 274, 284
416Mesna[1] Coenzyme M---[11] 11, 13, 44, 45, 49, 51, 60, 65, 85, 96, 164
417Metformin[1] Metformin[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
418Methotrexate[1] Methotrexate[2] D00142 ,
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
419Methotrexate and folic acid[2] Folic acid,
Methotrexate		[3] D00070 ,
D00142 ,
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 49
420Methyl prednisolone[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 43, 49, 96
421Methylprednisolone[1] Methylprednisolone[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
422METHYLPREDNISOLONE SODIUM SUCCINATE[1] Methylprednisolone[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[6] 13, 46, 49, 50, 51, 211
423MHS552----[1] 49
424MICOFENOLICO ACIDO[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 49
425Milatuzumab[1] Milatuzumab[1] D08944 [1] CD74 💬[3] Antigen processing and presentation, Herpes simplex virus 1 infection, Tuberculosis 💬[1] 49
426Milnacipran[1] Milnacipran[1] D08222 [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 46, 49
427Mizoribine[1] Mizoribine[1] D01392 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[8] 46, 49, 51, 53, 66, 94, 222, 224
428MMF----[15] 13, 35, 40, 46, 49, 50, 51, 60, 65, 66, 162, 222, 224, 226, 299
429MODAFINIL[1] Modafinil[1] D01832 --[4] 6, 13, 49, 93
430Moderna mRNA-1273----[5] 13, 35, 46, 49, 51
431MONITOR[1] Methamidophos---[20] 2, 11, 13, 19, 28, 46, 49, 58, 65, 70, 81, 85, 86, 98, 113, 118, 129, 298, 299, 300
432Mosunetuzumab[1] Mosunetuzumab[1] D11463 [2] CD3E,
MS4A1 💬		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 49
433Moxifloxacin[1] Moxifloxacin[2] D00874 ,
D08237 		--[9] 2, 6, 46, 49, 85, 86, 113, 240, 299
434MPA----[6] 13, 35, 46, 49, 51, 60
435MRA 003 US----[1] 49
436MRI, Venipuncture----[1] 49
437MRNA COVD19 vaccine----[3] 49, 53, 271
438MSC treatment----[1] 49
439MSC2364447C----[2] 13, 49
440MT-1303 High dose----[1] 49
441MT-1303 Low dose----[1] 49
442MTX----[14] 13, 35, 40, 46, 49, 50, 51, 60, 84, 96, 97, 107, 162, 271
443Multivitamin----[1] 49
444Mycophenolate[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
445Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
446Mycophenolate mofetil (MMF)[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[7] 13, 49, 51, 60, 65, 66, 222
447Mycophenolate Mofetil 500mg[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[3] 49, 51, 61
448Mycophenolate motetil[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 49
449Mycophenolic acid[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[8] 11, 43, 49, 51, 60, 66, 96, 222
450Myfortic[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[5] 49, 66, 162, 222, 228
451MYFORTIC*50CPR RIV 360MG[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 49
452N-(5-{4-[(3,3-dimethyl-1-azetidinyl)carbonyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide----[1] 49
453N-Acetylcysteine[1] Acetylcysteine[1] D00221 --[11] 6, 13, 19, 20, 49, 58, 85, 111, 164, 299, 337
454Nelfinavir[1] Nelfinavir[2] D00899 ,
D08259 		--[3] 49, 265, 331
455Nicotinamide[1] Nicotinamide[1] D00036 --[8] 2, 6, 18, 49, 65, 107, 162, 191
456Nipocalimab[1] Nipocalimab[1] D11666 [1] FCGRT 💬-[5] 11, 46, 49, 53, 61
457Nivolumab[1] Nivolumab[1] D10316 [1] PDCD1 💬[3] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159
458NNC 0151-0000-0000----[2] 46, 49
459NNC0114-0006----[3] 46, 49, 96
460Non applicabile----[4] 13, 49, 51, 256
461Non-myeloablative high dose immunosuppressive therapy conditioning (HDIT)----[1] 49
462Norethindrone[1] Norethisterone[2] D00182 ,
D00953 		[1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[4] 13, 46, 49, 299
463Normal Saline----[18] 6, 13, 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 271, 276, 296, 299
464NOX-E36----[1] 49
465Null----[16] 6, 13, 15, 28, 37, 46, 49, 51, 63, 86, 90, 96, 97, 107, 145, 271
466OBINUTUZUMAB[1] Obinutuzumab[1] D09321 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[2] 49, 222
467Obinutuzumab administration[1] Obinutuzumab[1] D09321 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 49
468OCRELIZUMAB[1] Ocrelizumab[1] D05218 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[3] 13, 46, 49
469Olive[1] Olea europaea leaf---[3] 13, 49, 53
470Olive oil[2] Olea europaea leaf,
Olive oil		[1] D03311 --[3] 13, 49, 53
471Olumiant[1] Baricitinib[1] D10308 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[4] 46, 49, 93, 107
472Olumiant - EU/1/16/1170/001-008[1] Baricitinib[1] D10308 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 49
473Olumiant - EU/1/16/1170/009-016[1] Baricitinib[1] D10308 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 49
474Omacor----[1] 49
475Omega-3[1] Omega-3 fatty acids---[7] 13, 46, 49, 66, 79, 96, 299
476Oral prednisolone[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 49, 96, 145
477Oral Prednisone 5mg[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 49
478ORENCIA[1] Abatacept[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[14] 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 160, 222, 271
479ORENCIA 125 mg solution for injection in pre-filled syringe[1] Abatacept[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[3] 46, 49, 53
480Ortho-novum[1] Mestranol[1] D00575 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 46, 49
481Ortho-Novum 777[1] Mestranol[1] D00575 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 49
482Other: Blood drawing only Group C----[1] 49
483Other: Blood draws----[3] 49, 51, 85
484Other: Clinical data collection----[3] 49, 51, 85
485Other: Coaching Sessions----[1] 49
486Other: Concomitant Medication----[1] 49
487Other: corn starch[1] Starch, corn[1] D05297 --[1] 49
488Other: Drug free----[1] 49
489Other: Fitbit Activity Monitor[1] Methamidophos---[1] 49
490Other: Genetic data/DNA/RNA----[3] 49, 51, 85
491Other: Group B SLE one blood donation----[1] 49
492Other: GSK2586184 single dose taken with food----[1] 49
493Other: GSK2586184 single dose taken without food----[1] 49
494Other: immunologic technique----[1] 49
495Other: ISA 51 VG----[1] 49
496Other: Laboratory Biomarker Analysis----[21] 11, 13, 14, 26, 28, 34, 49, 51, 60, 62, 65, 89, 96, 97, 205, 232, 283, 284, 285, 298, 331
497Other: Other biological samples to biobank (skin, lung and muscle biopsies----[3] 49, 51, 85
498Other: Pharmacokinetic analysis----[1] 49
499Other: SLE treatment----[1] 49
500Other: Smartphone Application----[1] 49
501Other: standard of care----[7] 13, 49, 64, 85, 96, 245, 246
502Other: Standard therapy----[1] 49
503Other: Standard treatment according to the Clinical protocols----[3] 49, 51, 235
504Other: Ultrasonography assessment----[1] 49
505Oxygen[1] Oxygen[1] D00003 --[20] 6, 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 168, 193, 226, 271, 294, 299, 330
506Ozone[1] Ozone---[3] 49, 51, 226
507P 140----[1] 49
508PAH----[3] 49, 53, 86
509Paquinimod[1] Paquinimod---[2] 49, 51
510Paquinimod (ABR-215757)[1] Paquinimod---[1] 49
511PARACETAMOL[1] Acetaminophen[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[6] 3, 6, 13, 35, 46, 49
512PF-04236921----[2] 49, 96
513PF-06700841[1] PF-06700841---[3] 49, 96, 97
514PF-06700841 15 mg[1] PF-06700841---[1] 49
515PF-06700841 25mg[1] PF-06700841---[1] 49
516PF-06700841 30 mg[1] PF-06700841---[1] 49
517PF-06700841 45 mg[1] PF-06700841---[1] 49
518PF-06700841 5 mg[1] PF-06700841---[3] 49, 96, 97
519PF-06700841 5mg[1] PF-06700841---[1] 49
520PF-06700841-15[1] PF-06700841---[3] 49, 96, 97
521PF-06835375----[3] 46, 49, 63
522Phosphate[1] Phosphate ion---[33] 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
523Phosphate-buffered saline[1] Phosphate ion---[1] 49
524Pioglitazone[1] Pioglitazone[2] D00945 ,
D08378 		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
525Pitavastatin[1] Pitavastatin---[1] 49
526Placebo----[27] 3, 5, 6, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276
527Plaquenil----[4] 46, 49, 53, 96
528Plasmapheresis----[3] 11, 49, 222
529Pneumovax----[3] 46, 49, 96
530Pooled mesenchymal stem cell----[1] 49
531Positron Emission Tomography----[4] 40, 46, 49, 96
532Prasterone[1] Prasterone[1] D08409 [3] AR,
ESR1,
ESR2 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 49
533Prasterone (GL701)[1] Prasterone[1] D08409 [3] AR,
ESR1,
ESR2 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 49
534Pravastatin[1] Pravastatin[2] D00893 ,
D08410 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
535PREDNISOLONE[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
536Prednisolone/Prednisone[2] Prednisolone,
Prednisone		[9] D00472 ,
D00473 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 49
537Prednisona[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 46, 49, 222
538Prednisone[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
539Prednisone Acetate[3] Acetate,
Prednisone,
Prednisone acetate		[2] D00473 ,
D08416 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[4] 40, 46, 49, 224
540Prednisone discontinuation[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 49
541Premarin and Provera----[1] 49
542Prevenar® and Pneumo23®----[1] 49
543Proleukin[1] Aldesleukin[1] D00748 [3] IL2RA,
IL2RB,
IL2RG 💬		[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[3] 2, 49, 65
544Quinipril----[1] 49
545R-salbutamol[2] Levosalbutamol,
Salbutamol		[2] D02147 ,
D08124 		[1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 49
546R-salbutamol sulphate[2] Levosalbutamol,
Salbutamol		[2] D02147 ,
D08124 		[1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 49
547R932333----[1] 49
548Rabbit[1] Rabbit---[8] 11, 13, 49, 51, 60, 65, 96, 285
549Rabbit anti-thymocyte globulin[1] Rabbit---[2] 49, 65
550Rabbit antithymocyte globulin[2] Antithymocyte immunoglobulin (rabbit),
Rabbit		---[3] 49, 60, 96
551Radiation: Fluorine F 18 Clofarabine[1] Clofarabine[1] D03546 [3] POLA1,
POLA2,
RRM1 💬		[6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[4] 40, 46, 49, 96
552Radiation: Total Body Irradiation----[7] 36, 49, 51, 60, 65, 283, 284
553Ramipril[1] Ramipril[1] D00421 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257
554RANKL/OPG ratio----[1] 49
555Rapamycin[1] Sirolimus[1] D00753 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[19] 2, 15, 34, 35, 46, 49, 51, 60, 61, 67, 86, 89, 96, 157, 158, 193, 256, 278, 279
556Raptiva[1] Efalizumab[1] D03959 [1] ITGAL 💬[12] Cell adhesion molecules, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
557RAYOS[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 49
558RC18 160 mg plus standard therapy----[1] 49
559RC18 240 mg plus standard therapy----[1] 49
560RC18 80 mg plus standard therapy----[1] 49
561RECOMBINANT FACTOR FC FUSION PROTEIN[1] Iron polymaltose---[2] 46, 49
562Recombinant zoster vaccine----[1] 49
563Reduced Intensity Allogeneic Transplant----[2] 49, 51
564Remicade[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[9] 40, 46, 49, 56, 84, 85, 96, 97, 271
565RhuMab 2H7----[3] 13, 46, 49
566RhuMAb IFNalpha----[1] 49
567Rigerimod----[1] 49
568RIQUENT----[1] 49
569Rituxan (rituximab)[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 49
570Rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[49] 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
571Rivaroxaban[1] Rivaroxaban[1] D07086 [1] F10 💬[1] Complement and coagulation cascades 💬[5] 46, 49, 75, 91, 210
572Ro 106-1443----[1] 49
573RO 496-4913----[2] 46, 49
574RO7010939/F13----[1] 49
575Rontalizumab[1] Rontalizumab[1] D09662 [13] IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬		[25] Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 49
576Rosuvastatin[1] Rosuvastatin[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
577ROSUVASTATIN CALCIUM[2] Calcium,
Rosuvastatin		[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[4] 49, 79, 97, 299
578Royal jelly[1] Royal jelly[1] D09754 --[1] 49
579Rozibafusp Alfa----[1] 49
580RSLV-132----[2] 49, 53
581Salbutamol[1] Salbutamol[1] D02147 [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 3, 11, 49, 85, 86, 111, 228, 256, 299
582SAR113244----[1] 49
583SAR441344----[3] 13, 49, 53
584SAR441344 IV----[2] 13, 49
585SAR441344 SC----[2] 13, 49
586SBI-087----[2] 46, 49
587SC belimumab 200 mg[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
588Sifalimumab[1] Sifalimumab[1] D09668 [13] IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬		[25] Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 49
589Sifalimumab 1,200 mg[1] Sifalimumab[1] D09668 [13] IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬		[25] Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 49
590Sifalimumab 200 mg[1] Sifalimumab[1] D09668 [13] IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬		[25] Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 49
591Sifalimumab 600 mg[1] Sifalimumab[1] D09668 [13] IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬		[25] Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 49
592Simvastatin[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
593Sirolimus[1] Sirolimus[1] D00753 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[36] 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 89, 98, 127, 137, 157, 158, 192, 222, 277, 278, 279, 280, 281, 283, 285, 331
594SM101----[3] 49, 63, 66
595SM934----[1] 49
596Solu-Medrol[1] Methylprednisolone hemisuccinate[1] D05000 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 13, 49, 50, 51, 53, 97, 211
597Soluble Fc receptor----[1] 49
598Soluble Fc-gamma receptor IIb----[1] 49
599SQ Fludarabine[1] Fludarabine[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[1] 49
600Standard dose of HCQ----[1] 49
601Standard dose of rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 49
602Standard of Care----[10] 6, 13, 46, 49, 51, 63, 64, 79, 171, 271
603Standard therapy----[2] 49, 97
604Standard therapy (Excluding Immunosuppressants)----[1] 49
605Standard therapy (Including Immunosuppressants)----[1] 49
606Standard-of-care treatment----[1] 49
607Stelara[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[6] 49, 56, 96, 97, 269, 271
608STELARA®[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[3] 49, 96, 97
609Steroid Drug----[2] 46, 49
610Steroid Taper----[1] 49
611Subcuvia----[3] 14, 49, 65
612Sugar pill----[8] 5, 6, 49, 67, 70, 86, 206, 210
613Sulfamethoxazole[1] Sulfamethoxazole[1] D00447 --[5] 44, 49, 61, 85, 299
614Sulfate[1] Sulfate ion---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
615Switch to Myfortic[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 49
616TAB08----[2] 46, 49
617TABALUMAB[1] Tabalumab[1] D10083 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 46, 49
618Tabalumab Auto-Injector[1] Tabalumab[1] D10083 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 46, 49
619Tabalumab Prefilled Syringe[1] Tabalumab[1] D10083 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 46, 49
620TACI-Fc5[1] Atacicept[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[3] 13, 46, 49
621Tacrolimus[1] Tacrolimus[2] D00107 ,
D08556 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
622TAK-079----[3] 11, 49, 63
623Telitacicept----[2] 48, 49
624Thalidomide[1] Thalidomide[1] D00754 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
625The generic name is warfarin and many producers will be involved[1] Warfarin[3] D00564 ,
D01280 ,
D08682 		[2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[1] 49
626TJ202 injection----[1] 49
627TLR7/8 Antagonist (10mg)----[1] 49
628TLR7/8 Antagonist (2.5mg)----[1] 49
629Tocilizumab[1] Tocilizumab[1] D02596 [1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
630Tocopherol[1] Tocopherol[1] D02332 --[5] 13, 49, 206, 257, 298
631Tocopherol acetate[3] Acetate,
Tocopherol,
alpha-Tocopherol acetate		[1] D02332 --[1] 49
632Toctino[1] Alitretinoin[1] D02815 [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		[19] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 49
633Toctino®[1] Alitretinoin[1] D02815 [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		[19] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 49
634Tofacitinib[1] Tofacitinib[1] D09970 [4] JAK1,
JAK2,
JAK3,
TYK2 💬		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
635TOFACITINIB CITRATE[1] Tofacitinib[1] D09970 [4] JAK1,
JAK2,
JAK3,
TYK2 💬		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[5] 46, 49, 97, 107, 271
636Trade Name Xarelto[1] Rivaroxaban[1] D07086 [1] F10 💬[1] Complement and coagulation cascades 💬[1] 49
637Trimethoprim[1] Trimethoprim[2] D00145 ,
D06236 		--[7] 36, 44, 49, 60, 61, 85, 299
638Trimethoprim-Sulfamethoxazole[2] Sulfamethoxazole,
Trimethoprim		[3] D00145 ,
D00447 ,
D06236 		--[3] 49, 61, 299
639Triptorelin[1] Triptorelin[1] D06247 [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[2] 49, 76
640Triptorelin pamoate[1] Triptorelin[1] D06247 [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[2] 49, 76
641TRU-015[1] TRU-015---[3] 46, 49, 222
642Truxima[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[2] 49, 222
643TV-4710----[1] 49
644Upadacitinib[1] Upadacitinib[1] D10994 [1] JAK1 💬[27] Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[8] 40, 41, 46, 49, 96, 97, 107, 271
645Urine sample----[3] 49, 51, 61
646Ustekinumab[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
647Ustekinumab (approximately 6 mg/kg)[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 49
648Ustekinumab 90 mg[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[4] 49, 50, 93, 96
649Ustekinumab 90 milligram (mg)[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 49
650Ustekinumab IV[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[2] 49, 97
651Ustekinumab SC[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[2] 49, 97
652Vaccination----[1] 49
653Vaccine----[1] 49
654VAY736----[7] 13, 35, 46, 49, 53, 85, 95
655Versus hydroxychloroquine[1] Hydroxychloroquine[1] D08050 --[1] 49
656VIB7734----[4] 49, 50, 51, 53
657VIB7734, MEDI7734----[1] 49
658VIP----[3] 49, 51, 86
659Vitamin D[1] Vitamin D---[24] 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299
660Vitamin D 25(OH)D[1] Vitamin D---[1] 49
661Vitamin D2[1] Ergocalciferol[1] D00187 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[3] 49, 84, 299
662Vitamin D2 ( calciferol )[2] Ergocalciferol,
Vitamin D		[1] D00187 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 49
663Vitamin D3[1] Cholecalciferol[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[12] 6, 13, 20, 46, 49, 51, 53, 60, 65, 96, 97, 299
664Vitamin D3 400 IU[1] Cholecalciferol[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 49
665Vitamin D3 6000 IU[1] Cholecalciferol[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 49
666Vitamins: B6, B12, and folate[1] Folic acid[1] D00070 --[1] 49
667Vobarilizumab[1] Vobarilizumab[1] D11005 --[1] 49
668Warfarin[1] Warfarin[3] D00564 ,
D01280 ,
D08682 		[2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
669Warfarin Sodium[1] Warfarin[3] D00564 ,
D01280 ,
D08682 		[2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[1] 49
670Xarelto[1] Rivaroxaban[1] D07086 [1] F10 💬[1] Complement and coagulation cascades 💬[2] 49, 210
671XmAb5871----[2] 49, 300
672Zishenqing----[1] 49
673Zostavax[1] Varicella zoster vaccine (live/attenuated)---[2] 46, 49
674Zostavax vaccine[1] Varicella zoster vaccine (live/attenuated)---[2] 46, 49