Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(18)F-FDG----[1] 85
200258901----[1] 85
300322900----[1] 85
418F-FDG[1] Fludeoxyglucose (18F)---[13] 5, 6, 7, 8, 13, 41, 46, 53, 84, 85, 96, 127, 300
53-[4-(1H-imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophene-2-[(N-butyloxylcarbamate)-sulphonamide] sodium salt----[2] 51, 85
6534-1508----[1] 85
768Ga-BMV101----[1] 85
8[18F]-FBA-A20FMDV2----[1] 85
9[18F]FP-R01-MG-F2----[2] 85, 94
10[68Ga]CBP8----[1] 85
11Acetate[1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
12Acetylcysteine[1] Acetylcysteine[1] D00221 --[20] 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
13Acetylcysteine Effervescent Tablets[1] Acetylcysteine[1] D00221 --[1] 85
14ACT-064992----[5] 51, 85, 86, 88, 210
15ACT-064992 (macitentan)[1] Macitentan[1] D10135 [2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
16Adult human mesenchymal stem cells[1] Remestemcel-L[1] D09719 --[2] 85, 96
17Aerosol interferon-gamma----[1] 85
18Air----[8] 3, 13, 51, 58, 85, 97, 193, 299
19ALEMTUZUMAB[1] Alemtuzumab[1] D02802 [1] CD52 💬-[17] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284
20Allogeneic Adult Human Mesenchymal Stem Cells (hMSCs)[1] Remestemcel-L[1] D09719 --[1] 85
21AlloRx----[8] 2, 6, 13, 46, 51, 85, 90, 226
22Ambrisentan[1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 51, 84, 85, 86, 88, 210, 211
23Antimicrobial therapy: Co-trimoxazole or Doxycycline[1] Doxycycline[5] D00307 ,
D02129 ,
D03903 ,
D03904 ,
D07876 		--[1] 85
24AP01----[1] 85
25ART-123----[1] 85
26AT 10----[2] 6, 85
27Atezolizumab[1] Atezolizumab[1] D10773 [1] CD274 💬[2] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬[1] 85
28Auto-titrating oxygen system[1] Oxygen[1] D00003 --[1] 85
29Autoantibody Reductive Therapy----[1] 85
30Autologous Adipose Derived MSCs (ADMSCs)----[1] 85
31Autologous mesenchymal stem cells derived from bone marrow----[1] 85
32Autologous Stromal Vascular Fraction (SVF)----[1] 85
33Aviptadil[1] Aviptadil[1] D12127 --[5] 49, 51, 84, 85, 86
34Aviptadil, 66 microgram/mL[1] Aviptadil[1] D12127 --[1] 85
35AZAPRED----[1] 85
36Azathioprine[1] Azathioprine[2] D00238 ,
D03033 		--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
37Azathioprine/prednisone[2] Azathioprine,
Prednisone		[3] D00238 ,
D00473 ,
D03033 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 85
38AZD5055----[1] 85
39Azithromycin[1] Azithromycin[3] D02134 ,
D06390 ,
D07486 		--[6] 13, 84, 85, 96, 228, 299
40BAL----[5] 49, 51, 84, 85, 299
41Bardoxolone[1] Bardoxolone[1] D09584 --[7] 66, 67, 84, 85, 86, 218, 222
42Bardoxolone methyl[2] Bardoxolone,
Bardoxolone methyl		[2] D09584 ,
D09585 		--[7] 66, 67, 84, 85, 86, 218, 222
43BBT-877, Multiple doses----[1] 85
44BBT-877, Single dose----[1] 85
45Beclometasone dipropionate[1] Beclomethasone dipropionate[2] D00689 ,
D07495 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 85, 97
46Bevacizumab[1] Bevacizumab[1] D06409 [1] VEGFA 💬[24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
47BG00011----[1] 85
48BI 1015550----[1] 85
49BIBF 1120----[2] 51, 85
50BIBF 1120 ES----[1] 85
51BIBF1120----[1] 85
52BLD-2660----[1] 85
53Blood sample collection----[1] 85
54BMS-986020[1] BMS-986020---[2] 51, 85
55BMS-986278----[1] 85
56Bone marrow mesenchymal stem cells----[1] 85
57Bosentan[1] Bosentan[2] D01227 ,
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
58Broncho-Vaxom[1] OM85---[1] 85
59Bronchoalveolar lavage (BAL fluid)----[3] 49, 51, 85
60C21----[2] 51, 85
61Carbon[1] Activated charcoal---[9] 6, 46, 50, 51, 85, 86, 96, 97, 298
62Carbon monoxide[2] Activated charcoal,
Carbon monoxide		[1] D09706 --[3] 85, 86, 298
63Carboplatin[1] Carboplatin[1] D01363 --[4] 28, 34, 60, 85
64Caveolin-1-Scaffolding-Protein-Derived Peptide (LTI-03)----[1] 85
65CBDCA[1] Carboplatin[1] D01363 --[1] 85
66CC----[14] 13, 28, 46, 49, 51, 56, 84, 85, 96, 97, 98, 162, 202, 271
67CC-90001----[1] 85
68CC-930----[1] 85
69CD3/CD19 negative hematopoietic stem cells----[1] 85
70Centricyte 1000----[2] 85, 229
71CNC----[1] 85
72CNTO 888 1 mg/kg----[1] 85
73CNTO 888 15 mg/kg----[1] 85
74CNTO 888 5 mg/kg----[1] 85
75CNTO888----[1] 85
76CO----[6] 6, 13, 53, 70, 85, 149
77CO-TRIMOXAZOLE----[1] 85
78Combination Product: EGCG + Nintedanib[2] Epigallocatechin gallate,
Nintedanib		[1] D10481 [8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬		[34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85
79Combination Product: EGCG + Pirfenidone[2] Epigallocatechin gallate,
Pirfenidone		[1] D01583 [6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬		[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85
80Combined Plasma Exchange (PEX), Rituximab, and Corticosteroids[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 85
81COMPOUND 21----[1] 85
82Corticosteroid (prednisolone)[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 85
83Cotrimoxazole----[2] 85, 97
84Cravit----[1] 85
85Cromoglicate[1] Cromoglicic acid[2] D00526 ,
D07753 		--[1] 85
86Cromoglicato disodico----[1] 85
87Cromoglycate[1] Cromoglicic acid[2] D00526 ,
D07753 		--[1] 85
88Cromolyn[1] Cromoglicic acid[2] D00526 ,
D07753 		--[3] 2, 85, 98
89Cromolyn sodio (cromoglicato disodico, DSCG)[1] Cromoglicic acid[2] D00526 ,
D07753 		--[1] 85
90Cromolyn Sodium[1] Cromoglicic acid[2] D00526 ,
D07753 		--[1] 85
91Cromolyn sodium [Disodium Cromoglycate][1] Cromoglicic acid[2] D00526 ,
D07753 		--[1] 85
92CSL312----[1] 85
93Cyclophosphamide[1] Cyclophosphamide[2] D00287 ,
D07760 		--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
94Cyclosphamine----[1] 85
95Cysteine[1] Cysteine[2] D00026 ,
D02326 		--[11] 6, 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
96Dabigatran[1] Dabigatran[1] D09707 [1] F2 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[4] 51, 85, 91, 124
97Dasatinib[1] Dasatinib[2] D03658 ,
D06414 		[8] ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		[77] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 51, 85
98Dasatinib + Quercetin[2] Dasatinib,
Quercetin		[2] D03658 ,
D06414 		[8] ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		[77] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[1] 85
99DEX284----[1] 85
100Dextromethorphan[1] Dextromethorphan[3] D00848 ,
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
101Diagnostic Test: Metabolomics----[1] 85
102Diagnostic Test: PET Imaging----[1] 85
103Diet A group----[1] 85
104Diet B group----[1] 85
105Diet C group----[1] 85
106Disodium cromoglycate (DSCG)[1] Cromoglicic acid[2] D00526 ,
D07753 		--[1] 85
107Disodium Cromoglycate [cromolyn sodium][1] Cromoglicic acid[2] D00526 ,
D07753 		--[1] 85
108Doxycycline[1] Doxycycline[5] D00307 ,
D02129 ,
D03903 ,
D03904 ,
D07876 		--[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
109DPA----[5] 2, 6, 13, 85, 127
110Durvalumab[1] Durvalumab[1] D10808 [1] CD274 💬[2] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬[1] 85
111DWN12088----[1] 85
112EGCG[1] Epigallocatechin gallate---[9] 6, 8, 13, 17, 28, 85, 113, 206, 299
113Endobronchial infusion of adult mesenchymal stem cells----[1] 85
114ENDOXAN----[7] 13, 28, 43, 44, 85, 96, 222
115Epigallocatechin[1] Epigallocatechin---[5] 8, 13, 28, 85, 113
116Epigallocatechin-3-gallate (EGCG)[2] Epigallocatechin,
Epigallocatechin gallate		---[2] 28, 85
117Erivedge[1] Vismodegib[1] D09992 [1] SMO 💬[5] Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬[1] 85
118Esbriet[1] Pirfenidone[1] D01583 [6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬		[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[4] 46, 51, 85, 228
119ESBRIET - 267 MG - CAPSULA RIGIDA - USO ORALE - FLACONE (HDPE) 270 CAPSULE[1] Pirfenidone[1] D01583 [6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬		[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85
120Esbriet® (Pirfenidon)[1] Pirfenidone[1] D01583 [6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬		[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85
121Etanercept[1] Etanercept[1] D00742 [2] LTA,
TNF 💬		[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[16] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
122Etoposide[1] Etoposide[2] D00125 ,
D04107 		[2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331
123EZ-2053----[2] 85, 299
124EZ-2053 5mg/kg----[2] 85, 299
125FG-3019----[3] 85, 113, 222
126FG-3019 10mg/mL in 10 mL vials----[1] 85
127Fludarabine[1] Fludarabine[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[18] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
128Fludeoxyglucose[1] Fludeoxyglucose (18F)---[4] 34, 84, 85, 88
129Fluimucil----[4] 85, 94, 193, 298
130Fluimucil® 600 mg effervescent tablets----[1] 85
131FLUORINE (18F) FLUDEOXYGLUCOSE[1] Fludeoxyglucose[1] D01843 --[2] 84, 85
132Formoterol[1] Formoterol[3] D01373 ,
D05277 ,
D07990 		[1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 85, 228, 299
133Formoterol fumarate dihydrate[1] Formoterol[3] D01373 ,
D05277 ,
D07990 		[1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
134Fostair----[1] 85
135G-CSF[1] Filgrastim[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[16] 2, 6, 11, 13, 16, 47, 49, 51, 60, 62, 65, 85, 96, 284, 285, 331
136G048E03----[1] 85
137G321605----[3] 85, 96, 97
138G451990----[2] 51, 85
139Gallium68-Dota-Noc----[1] 85
140GB0139----[1] 85
141GB0139 (previously known as TD139)----[1] 85
142GBT440----[1] 85
143GBT440 300 mg capsule----[1] 85
144GBT440 300 mg tablet----[1] 85
145GC1008[1] Fresolimumab[1] D09620 [3] TGFB1,
TGFB2,
TGFB3 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[2] 85, 222
146Gefapixant[1] Gefapixant[1] D11349 [1] P2RX3 💬[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Taste transduction 💬[2] 85, 226
147GKT137831----[2] 85, 93
148GLPG1205----[3] 85, 96, 97
149GLPG1690----[2] 51, 85
150GLPG1690 600 mg QD----[1] 85
151Granulocyte Colony Stimulating Factor[1] Filgrastim[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[6] 2, 28, 36, 57, 65, 85
152GS-6624[1] Simtuzumab---[2] 85, 94
153GSK2126458----[1] 85
154GSK3008348----[1] 85
155GSK3008348 Nebuliser solution----[1] 85
156HEC 68498----[1] 85
157HEC585----[1] 85
158High dose BIBF 1120 twice daily----[1] 85
159Humanized anti-alpha v beta 6 mAb----[1] 85
160Hydroxyurea[1] Hydroxyurea[1] D00341 [1] RRM2 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284
161Hyperoxia----[2] 51, 85
162Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) Treatment[1] Xenon[2] D01901 ,
D06339 		--[1] 85
163Hyperpolarized 129 Xenon Gas Comparing Progressive Pulmonary Fibrosis Treatment[1] Xenon[2] D01901 ,
D06339 		--[1] 85
164Hyperpolarized 129-Xenon gas[1] Xenon[2] D01901 ,
D06339 		--[1] 85
165Hyperpolarized Xe129----[2] 85, 299
166HZN-825----[2] 51, 85
167IDL-2965 Oral Capsule----[1] 85
168Ifenprodil[1] Ifenprodil[1] D08064 [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 85
169Iloprost[1] Iloprost[1] D02721 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[4] 51, 84, 85, 86
170Iloprost Inhalation Solution (Ventavis)[1] Iloprost[1] D02721 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[2] 85, 86
171Imatinib[1] Imatinib[2] D01441 ,
D08066 		[3] ABL1,
KIT,
PDGFRA 💬		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
172Imatinib Mesylate (Gleevec)[1] Imatinib[2] D01441 ,
D08066 		[3] ABL1,
KIT,
PDGFRA 💬		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[1] 85
173Immukin----[1] 85
174Inhaled carbon monoxide[2] Activated charcoal,
Carbon monoxide		[1] D09706 --[1] 85
175Inhaled Nitric Oxide[1] Nitric Oxide[1] D00074 --[2] 85, 86
176Inhaled Nitric Oxide - 30 mcg/kg IBW/hr[1] Nitric Oxide[1] D00074 --[1] 85
177Inhaled Nitric Oxide 5,10,15 mcg/Kg IBW/hr[1] Nitric Oxide[1] D00074 --[1] 85
178Inhaled nitric oxide 75 mcg/kg IBW/hr[1] Nitric Oxide[1] D00074 --[2] 85, 86
179Inhaled TD139----[1] 85
180Inhaled Treprostinil[1] Treprostinil[1] D06213 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[3] 84, 85, 86
181INO----[2] 85, 86
182INOmax[1] Nitric Oxide[1] D00074 --[3] 85, 294, 299
183INOmax 400ppm mol/mol inhalation gas[1] Nitric Oxide[1] D00074 --[2] 85, 299
184INS018_055----[1] 85
185Interferon alpha oral lozenge----[1] 85
186Interferon Gamma[1] Interferon Gamma---[8] 18, 65, 85, 107, 228, 299, 301, 326
187INTERFERON GAMMA-1B[2] Interferon Gamma,
Interferon gamma-1b		[1] D00747 [2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326
188Interferon gamma-1b (Actimmune)[2] Interferon Gamma,
Interferon gamma-1b		[1] D00747 [2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[1] 85
189Interferon-alpha lozenges----[1] 85
190Interferon-gamma 1b----[1] 85
191Intermediate dose BIBF 1120 twice daily----[1] 85
192IV Deployment Of cSVF In Sterile Normal Saline IV Solution----[2] 85, 229
193IW001----[1] 85
194Jaktinib Dihydrochloride Monohydrate 50mg BID and Mimic tablets of jakitinib hydrochloride 75mg BID and Acetylcysteine Effervescent Tablets[1] Acetylcysteine[1] D00221 --[1] 85
195Jaktinib Dihydrochloride Monohydrate 75mg BID and Mimic tablets of jakitinib hydrochloride 50mg BID and Acetylcysteine Effervescent Tablets[1] Acetylcysteine[1] D00221 --[1] 85
196Jin-shui Huan-xian granule----[1] 85
197KD025----[1] 85
198L - Antineoplastic and immunomodulating agents----[1] 85
199L01 - Antineoplastic agents----[1] 85
200L01X - Other antineoplastic agents----[1] 85
201L01XE - Protein kinase inhibitors----[1] 85
202L01XE31 - Nintedanib[1] Nintedanib[1] D10481 [8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬		[34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85
203Lanreotide[1] Lanreotide---[4] 67, 73, 85, 298
204LANREOTIDE ACETATE[2] Acetate,
Lanreotide		---[4] 67, 73, 85, 298
205Lansoprazole[1] Lansoprazole[1] D00355 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299
206LEBRIKIZUMAB[1] Lebrikizumab[1] D09633 [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 85
207Letairis[1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
208Letairis 10 mg[1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
209Letairis 5 mg[1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
210Letermovir[1] Letermovir[1] D10801 --[1] 85
211Liberase Enzyme (Roche)----[2] 85, 229
212Losartan[1] Losartan[2] D00357 ,
D08146 		[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
213Low dose BIBF 1120 twice daily----[1] 85
214Low dose BIBF1120 once daily----[1] 85
215LPA1----[1] 85
216Lung Spheroid Stem Cells 100 million----[1] 85
217Lung Spheroid Stem Cells 200 million----[1] 85
218Lung stem cells----[1] 85
219Macitentan[1] Macitentan[1] D10135 [2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 51, 85, 86, 88, 210
220Medical air[2] Medical air,
Oxygen		[1] D00003 --[3] 85, 86, 193
221Medical air (sham O2)[2] Medical air,
Oxygen		[1] D00003 --[1] 85
222Mesna[1] Coenzyme M---[11] 11, 13, 44, 45, 49, 51, 60, 65, 85, 96, 164
223MG-S-2525----[1] 85
224Microcannula Harvest Adipose Derived tissue stromal vascular fraction (tSVF)----[2] 85, 229
225Minocycline[1] Minocycline[2] D00850 ,
D05045 		--[13] 2, 6, 8, 13, 46, 85, 90, 94, 162, 201, 206, 280, 299
226MONITOR[1] Methamidophos---[20] 2, 11, 13, 19, 28, 46, 49, 58, 65, 70, 81, 85, 86, 98, 113, 118, 129, 298, 299, 300
227Montelukast[1] Montelukast[2] D00529 ,
D08229 		[1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228
228Morphine[1] Morphine[3] D00842 ,
D02271 ,
D08233 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298
229Morphine hydrochloride[1] Morphine[3] D00842 ,
D02271 ,
D08233 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 85
230MORPHINE SULFATE[2] Morphine,
Sulfate ion		[3] D00842 ,
D02271 ,
D08233 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[3] 46, 85, 86
231Moxifloxacin[1] Moxifloxacin[2] D00874 ,
D08237 		--[9] 2, 6, 46, 49, 85, 86, 113, 240, 299
232MRI----[5] 13, 70, 78, 85, 278
233Mycophenolate[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
234Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
235N-acetyl Cysteine[1] Cysteine[2] D00026 ,
D02326 		--[7] 13, 19, 34, 85, 88, 296, 310
236N-Acetylcysteine[1] Acetylcysteine[1] D00221 --[11] 6, 13, 19, 20, 49, 58, 85, 111, 164, 299, 337
237N-Acetylcysteine, (NAC)[1] Acetylcysteine[1] D00221 --[1] 85
238Na----[3] 36, 46, 85
239NAC----[5] 34, 51, 85, 90, 299
240Nalbuphine[1] Nalbuphine[2] D00843 ,
D08246 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
241Nalbuphine ER[1] Nalbuphine[2] D00843 ,
D08246 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
242Nalbuphine Extended-Realease (ER) Tablets[1] Nalbuphine[2] D00843 ,
D08246 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
243Nalbuphine Extended-Release (ER) Tablets[1] Nalbuphine[2] D00843 ,
D08246 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
244NALBUPHINE HYDROCHLORIDE[1] Nalbuphine[2] D00843 ,
D08246 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
245Nandrolone[1] Nandrolone[1] D08250 [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 60, 85
246Nandrolone Decanoate[2] Nandrolone,
Nandrolone decanoate		[2] D00955 ,
D08250 		[1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 60, 85
247ND-L02-s0201----[1] 85
248ND-L02-s0201 for injection----[1] 85
249Nebivolol[1] Nebivolol[1] D05127 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 17, 85, 113, 167
250NINTEDANIB[1] Nintedanib[1] D10481 [8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬		[34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[5] 51, 85, 89, 227, 228
251NIP292 tablet----[1] 85
252NIP292 tablets----[1] 85
253Nitric Oxide[1] Nitric Oxide[1] D00074 --[8] 46, 85, 86, 98, 210, 251, 294, 299
254Nivolumab[1] Nivolumab[1] D10316 [1] PDCD1 💬[3] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159
255None----[16] 6, 46, 51, 65, 78, 84, 85, 96, 97, 140, 160, 161, 171, 231, 271, 299
256Octreotide[1] Octreotide[2] D00442 ,
D06495 		[1] SSTR2 💬[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[7] 67, 75, 84, 85, 89, 193, 227
257Ofev[1] Nintedanib[1] D10481 [8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬		[34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[5] 51, 85, 89, 227, 228
258Ofev 100 mg capsule[1] Nintedanib[1] D10481 [8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬		[34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85
259Ofev 150 mg capsule[1] Nintedanib[1] D10481 [8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬		[34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85
260OFEV®----[1] 85
261Omeprazole[1] Omeprazole[4] D00455 ,
D01207 ,
D05259 ,
D05261 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
262Omeprazole (UK licensed generic product)[1] Omeprazole[4] D00455 ,
D01207 ,
D05259 ,
D05261 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 85
263ORIN1001----[1] 85
264Other: 60% Oxygen[1] Oxygen[1] D00003 --[1] 85
265Other: Blood draws----[3] 49, 51, 85
266Other: BSC----[1] 85
267Other: Clinical data collection----[3] 49, 51, 85
268Other: Control----[9] 6, 19, 67, 70, 75, 85, 97, 162, 193
269Other: Cough monitor[1] Methamidophos---[1] 85
270Other: Genetic data/DNA/RNA----[3] 49, 51, 85
271Other: Medical air[2] Medical air,
Oxygen		[1] D00003 --[1] 85
272Other: No Intervention: Standard of Care----[1] 85
273Other: Other biological samples to biobank (skin, lung and muscle biopsies----[3] 49, 51, 85
274Other: Oxygen[1] Oxygen[1] D00003 --[1] 85
275Other: Oxygen (2Liter/min)[1] Oxygen[1] D00003 --[1] 85
276Other: Oxygen (4Liter/min)[1] Oxygen[1] D00003 --[1] 85
277Other: Pulmonary rehabilitation program----[1] 85
278Other: standard of care----[7] 13, 49, 64, 85, 96, 245, 246
279Other: Untreated Cohort----[1] 85
280Oxygen[1] Oxygen[1] D00003 --[20] 6, 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 168, 193, 226, 271, 294, 299, 330
281Oxygen 40 %[1] Oxygen[1] D00003 --[1] 85
282Oxymizer® compared to CNC----[1] 85
283PA101----[1] 85
284Paclitaxel[1] Paclitaxel[2] D00491 ,
D05333 		[9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[2] 46, 85
285PAMREVLUMAB[1] Pamrevlumab[1] D10969 [1] CCN2 💬[2] Apelin signaling pathway, Hippo signaling pathway 💬[2] 85, 113
286Paroxetine[1] Paroxetine[4] D02260 ,
D02362 ,
D05374 ,
D05375 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85
287PBI4050----[2] 85, 299
288PD00377 Na-salt----[1] 85
289PET/CT using PET ligands [F-18]FDG and [F-18]DPA-714----[1] 85
290PIR, S-7701----[1] 85
291Pirfenidone[1] Pirfenidone[1] D01583 [6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬		[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
292Pirfenidone and nintedanib[2] Nintedanib,
Pirfenidone		[2] D01583 ,
D10481 		[14] CCL2,
FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
IL10,
IL1A,
IL1B,
IL6,
KDR,
PDGFRA,
PDGFRB,
TNF 💬		[106] AGE-RAGE signaling pathway in diabetic complications, Adherens junction, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemokine signaling pathway, Choline metabolism in cancer, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, Melanoma, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Phospholipase D signaling pathway, Prion disease, Prostate cancer, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85
293Pirfenidone or nintedanib[2] Nintedanib,
Pirfenidone		[2] D01583 ,
D10481 		[14] CCL2,
FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
IL10,
IL1A,
IL1B,
IL6,
KDR,
PDGFRA,
PDGFRB,
TNF 💬		[106] AGE-RAGE signaling pathway in diabetic complications, Adherens junction, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemokine signaling pathway, Choline metabolism in cancer, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, Melanoma, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Phospholipase D signaling pathway, Prion disease, Prostate cancer, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85
294Pirfenidone Solution for Inhalation[1] Pirfenidone[1] D01583 [6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬		[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85
295Pirfenidoneone----[1] 85
296Placebo----[27] 3, 5, 6, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276
297PLN-74809----[2] 85, 94
298PLN-74809-000----[1] 85
299PLN-74809-020----[1] 85
300PMG1015 Dose 1----[1] 85
301PMG1015 Dose 2----[1] 85
302PMG1015 Dose 3----[1] 85
303PMG1015 Dose 4----[1] 85
304PMG1015 Dose 5----[1] 85
305PMG1015 Dose 6----[1] 85
306Pomalidomide[1] Pomalidomide[1] D08976 [2] IL6,
TNF 💬		[80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[6] 28, 34, 51, 85, 227, 331
307Pomalidomide (CC-4047[1] Pomalidomide[1] D08976 [2] IL6,
TNF 💬		[80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85
308PREDNISOLONE[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
309Prednisone[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
310PRIVIGEN 100mg/ml----[1] 85
311PRM-151[1] PRM-151---[1] 85
312PZN 8881655(RochePharma AG)----[1] 85
313QAX576----[4] 51, 85, 96, 98
314Quercetin[1] Quercetin---[5] 84, 85, 192, 285, 299
315Radiation: FDG PET scan----[1] 85
316Radiation: GSK26346763: ([18F]-FBA-A20FMDV2) IV infusion----[1] 85
317Radiation: Knottin tracer----[1] 85
318Recombinant human Pentraxin-2----[1] 85
319Recombinant human Pentraxin-2 (PRM-151)[1] PRM-151---[1] 85
320Remicade[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[9] 40, 46, 49, 56, 84, 85, 96, 97, 271
321Revatio[1] Sildenafil[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[3] 85, 86, 113
322Revatio 20 mg[1] Sildenafil[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 85
323Rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[49] 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
324Rixathon[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[3] 43, 46, 85
325RIXATHON 500 mg[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 85
326Ro 47-0203----[4] 51, 85, 86, 88
327RO0220912----[1] 85
328RO0280296----[1] 85
329RO5490255----[1] 85
330RO5490255/F01-02----[1] 85
331RO7490677----[1] 85
332RO7490677/ F01-02----[1] 85
333RO7490677/F01-01----[1] 85
334RO7490677/F01-02----[1] 85
335RO7490677/F01-03----[1] 85
336Routine steroid administration group----[1] 85
337RVT-1601----[1] 85
338RVT-1601 (formerly, PA101B)----[1] 85
339RVT-1601 (in precedenza PA101B)----[1] 85
340RXC007----[1] 85
341Salbutamol[1] Salbutamol[1] D02147 [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 3, 11, 49, 85, 86, 111, 228, 256, 299
342SAR100842----[2] 51, 85
343SAR156597----[2] 51, 85
344Saracatinab----[1] 85
345SEPTRIN----[1] 85
346SHR-1906----[1] 85
347Sildenafil[1] Sildenafil[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
348Sildenafil (50 mg)[1] Sildenafil[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 85
349Sildenafil and Losartan[2] Losartan,
Sildenafil		[4] D00357 ,
D02229 ,
D08146 ,
D08514 		[2] AGTR1,
PDE5A 💬		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 85
350Sildenafil citrate[1] Sildenafil[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 225
351Simtuzumab[1] Simtuzumab---[2] 85, 94
352Sirolimus[1] Sirolimus[1] D00753 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[36] 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 89, 98, 127, 137, 157, 158, 192, 222, 277, 278, 279, 280, 281, 283, 285, 331
353Sivelestat[1] Sivelestat[1] D03788 [1] ELANE 💬[3] Neutrophil extracellular trap formation, Systemic lupus erythematosus, Transcriptional misregulation in cancer 💬[3] 13, 85, 96
354SM04646----[1] 85
355SODIUM CROMOGLICATE[1] Cromoglicic acid[2] D00526 ,
D07753 		--[1] 85
356Standard of Care (SoC)----[1] 85
357Standard Steroid Treatment----[1] 85
358Sterile Normal Saline for Intravenous Use----[2] 85, 229
359Steroid pulse therapy group----[1] 85
360Sub-Study: Nintedanib[1] Nintedanib[1] D10481 [8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬		[34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85
361Sub-Study: Pirfenidone[1] Pirfenidone[1] D01583 [6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬		[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85
362Sulfamethoxazole[1] Sulfamethoxazole[1] D00447 --[5] 44, 49, 61, 85, 299
363Sulfate[1] Sulfate ion---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
364Sulphamethoxazole[1] Sulfamethoxazole[1] D00447 --[1] 85
365Symbicort----[2] 85, 228
366Tacrolimus[1] Tacrolimus[2] D00107 ,
D08556 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
367Taladegib[1] Taladegib[1] D10671 [1] SMO 💬[5] Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬[1] 85
368TBC----[3] 85, 94, 96
369TD-1058----[1] 85
370TD139----[1] 85
371Tetrandrine[1] Tetrandrine---[2] 46, 85
372Tetrathiomolybdate[1] Tetrathiomolybdate---[3] 85, 93, 171
373Thalidomide[1] Thalidomide[1] D00754 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
374Thalidomide Pharmion[1] Thalidomide[1] D00754 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[3] 85, 96, 97
375The Standard Steroid Treatment, Plasma Exchange and rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 85
376Thiotepa[1] Thiotepa[1] D00583 --[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
377Thrombomodulin Alfa[1] Thrombomodulin Alfa[1] D06410 [1] F2 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[1] 85
378Tiotropium[1] Tiotropium---[3] 55, 85, 299
379Tipelukast[1] Tipelukast[1] D06659 [1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 85
380TNX-650, rhuMAb anti-IL13, aIL-13, MILR1444A----[1] 85
381TR0311----[1] 85
382Tracleer[1] Bosentan[2] D01227 ,
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 13, 51, 84, 85, 86, 88, 210, 211
383Traditional Chinese Medicine Formulation----[1] 85
384Tralokinumab[1] Tralokinumab[1] D09979 [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[2] 85, 97
385Tralokinumab cohort 1[1] Tralokinumab[1] D09979 [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 85
386Tralokinumab cohort 2[1] Tralokinumab[1] D09979 [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 85
387Tralokinumab is a human recombinant monoclonal antibody (MAb) of the subclass that specifically binds human IL-13, blocking interactions with the IL-13 receptor[1] Tralokinumab[1] D09979 [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 85
388Treatment as Usual (TAU)----[1] 85
389Treprostinil[1] Treprostinil[1] D06213 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 51, 84, 85, 86, 88, 210
390Treprostinil sodium for inhalation[1] Treprostinil[1] D06213 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 85
391Treprostinil Ultrasonic Nebulizer[1] Treprostinil[1] D06213 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 85
392Trimethoprim[1] Trimethoprim[2] D00145 ,
D06236 		--[7] 36, 44, 49, 60, 61, 85, 299
393TRK-250----[1] 85
394UROMITEXAN[1] Coenzyme M---[1] 85
395Valganciclovir[1] Valganciclovir[1] D02495 --[6] 28, 60, 85, 97, 299, 331
396Vasoactive intestinal peptide----[1] 85
397VAY736----[7] 13, 35, 46, 49, 53, 85, 95
398VISMODEGIB[1] Vismodegib[1] D09992 [1] SMO 💬[5] Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬[1] 85
399Volibris[1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 88
400VRP700----[1] 85
401Warfarin[1] Warfarin[3] D00564 ,
D01280 ,
D08682 		[2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
402Xenon[1] Xenon[2] D01901 ,
D06339 		--[4] 22, 85, 228, 299
403Zileuton[1] Zileuton[1] D00414 [1] ALOX5 💬[6] Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[3] 85, 160, 164
404Ziritaxestat[1] Ziritaxestat[1] D11844 [1] ENPP2 💬[2] Ether lipid metabolism, Metabolic pathways 💬[2] 51, 85
405ZL-2102----[1] 85
406ZSP1603----[1] 85
407ZSP1603 12.5 mg----[1] 85
408ZSP1603 25 mg----[1] 85
409ZSP1603 50 mg----[1] 85
410ZSP1603 7.5 mg----[1] 85