1 |
Acetate
| [1] Acetate Acetate | - | - | - | [43] 1 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299 |
2 |
Acetylcysteine
| [3] Acetylcysteine Acetylcysteine; Mucomyst; N-acetylcysteine | [1] D00221
D00221
| - | - | [20] 6 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 |
3 |
Activated charcoal
| [1] Carbon Carbon | - | - | - | [9] 6 6, 46, 50, 51, 85, 86, 96, 97, 298 |
4 |
Alemtuzumab
| [4] Alemtuzumab Alemtuzumab; Campath; Lemtrada; MABCAMPATH | [1] D02802
D02802
| [1] CD52 CD52 💬 | - | [22] 13 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 |
5 |
Ambrisentan
| [3] Ambrisentan Ambrisentan; Letairis; VOLIBRIS | [1] D07077
D07077
| [1] EDNRA EDNRA 💬 | [7] Calcium signaling pathway Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [7] 51 51, 84, 85, 86, 88, 210, 211 |
6 |
Atezolizumab
| [1] Atezolizumab Atezolizumab | [1] D10773
D10773
| [1] CD274 CD274 💬 | [2] Cell adhesion molecules Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 | [1] 85 85 |
7 |
Aviptadil
| [1] Aviptadil Aviptadil | [1] D12127
D12127
| - | - | [5] 49 49, 51, 84, 85, 86 |
8 |
Azathioprine
| [3] Azathioprine Azathioprine; Azatioprina; Imuran | [2] D00238
D00238
,
D03033
| - | - | [21] 6 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 |
9 |
Azithromycin
| [5] AZITHROMYCIN AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX | [3] D02134
D02134
,
D06390
,
D07486
| - | - | [6] 13 13, 84, 85, 96, 228, 299 |
10 |
Bardoxolone
| [1] Bardoxolone Bardoxolone | [1] D09584
D09584
| - | - | [7] 66 66, 67, 84, 85, 86, 218, 222 |
11 |
Bardoxolone methyl
| [1] BARDOXOLONE METHYL BARDOXOLONE METHYL | [1] D09585
D09585
| - | - | [7] 66 66, 67, 84, 85, 86, 218, 222 |
12 |
Beclomethasone dipropionate
| [2] Beclometasone dipropionate Beclometasone dipropionate; Beclomethasone dipropionate | [2] D00689
D00689
,
D07495
| [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [3] 85 85, 97, 98 |
13 |
Bevacizumab
| [2] AVASTIN AVASTIN; Bevacizumab | [1] D06409
D06409
| [1] VEGFA VEGFA 💬 | [24] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬 | [9] 13 13, 34, 85, 86, 87, 89, 227, 280, 331 |
14 |
BMS-986020
| [1] BMS-986020 BMS-986020 | - | - | - | [2] 51 51, 85 |
15 |
Bosentan
| [2] Bosentan Bosentan; TRACLEER | [2] D01227
D01227
,
D07538
| [2] EDNRA EDNRA, EDNRB 💬 | [9] Calcium signaling pathway Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [11] 13 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 |
16 |
Carbon monoxide
| [1] Carbon Monoxide Carbon Monoxide | [1] D09706
D09706
| - | - | [8] 6 6, 13, 53, 70, 85, 86, 149, 298 |
17 |
Carboplatin
| [2] Carboplatin Carboplatin; CBDCA | [1] D01363
D01363
| - | - | [4] 28 28, 34, 60, 85 |
18 |
Cholecalciferol
| [5] CHOLECALCIFEROL CHOLECALCIFEROL; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3 | [1] D00188
D00188
| [1] VDR VDR 💬 | [5] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬 | [25] 6 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 |
19 |
Cinacalcet
| [1] Cinacalcet Cinacalcet | [2] D03504
D03504
,
D03505
| [1] CASR CASR 💬 | [2] NOD-like receptor signaling pathway NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action 💬 | [2] 85 85, 238 |
20 |
Coenzyme M
| [2] Mesna Mesna; UROMITEXAN | - | - | - | [11] 11 11, 13, 44, 45, 49, 51, 60, 65, 85, 96, 164 |
21 |
Cromoglicic acid
| [4] Cromoglicate Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium | [2] D00526
D00526
,
D07753
| - | - | [3] 2 2, 85, 98 |
22 |
Cyclophosphamide
| [6] Ciclofosfamida Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan | [2] D00287
D00287
,
D07760
| - | - | [45] 11 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 |
23 |
Cysteine
| [2] Cysteine Cysteine; Cysteine hydrochloride | [2] D00026
D00026
,
D02326
| - | - | [11] 6 6, 13, 19, 34, 84, 85, 88, 90, 254, 296, 310 |
24 |
Dabigatran
| [1] Dabigatran Dabigatran | [1] D09707
D09707
| [1] F2 F2 💬 | [8] Complement and coagulation cascades Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬 | [4] 51 51, 85, 91, 124 |
25 |
Dasatinib
| [1] Dasatinib Dasatinib | [2] D03658
D03658
,
D06414
| [8] ABL1 ABL1, EPHA2, FYN, KIT, LCK, PDGFRB, SRC, YES1 💬 | [77] Acute myeloid leukemia Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬 | [2] 51 51, 85 |
26 |
Dextromethorphan
| [4] Dextromethorphan Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta | [3] D00848
D00848
,
D03742
,
D03744
| [6] GRIN1 GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 | [20] Alcoholism Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬 | [11] 2 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 |
27 |
Dihydrotachysterol
| [0] | [1] D00299
D00299
| [1] VDR VDR 💬 | [5] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬 | [2] 6 6, 85 |
28 |
Dimercaprol
| [0] | [1] D00167
D00167
| - | - | [5] 49 49, 51, 84, 85, 299 |
29 |
Doxycycline
| [4] Doxycyclin Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets | [5] D00307
D00307
,
D02129
,
D03903
,
D03904
,
D07876
| - | - | [16] 13 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 |
30 |
Durvalumab
| [1] Durvalumab Durvalumab | [1] D10808
D10808
| [1] CD274 CD274 💬 | [2] Cell adhesion molecules Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 | [1] 85 85 |
31 |
Epigallocatechin
| [1] Epigallocatechin Epigallocatechin | - | - | - | [5] 8 8, 13, 28, 85, 113 |
32 |
Epigallocatechin gallate
| [2] EGCG EGCG; Epigallocatechin gallate | - | - | - | [9] 6 6, 8, 13, 17, 28, 85, 113, 206, 299 |
33 |
Etanercept
| [4] Benepali Benepali; Enbrel; Erelzi; Etanercept | [1] D00742
D00742
| [2] LTA LTA, TNF 💬 | [67] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [17] 15 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 |
34 |
Etoposide
| [1] Etoposide Etoposide | [2] D00125
D00125
,
D04107
| [2] TOP2A TOP2A, TOP2B 💬 | [1] Platinum drug resistance Platinum drug resistance 💬 | [11] 11 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 |
35 |
Filgrastim
| [7] Filgrastim Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio | [1] D03235
D03235
| [1] CSF3R CSF3R 💬 | [5] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬 | [34] 2 2, 6, 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 |
36 |
Fludarabine
| [4] FLUDARA FLUDARA; FLUDARABINA; Fludarabine; Fludarabine Phosphate | [2] D01907
D01907
,
D07966
| [1] RRM1 RRM1 💬 | [5] Drug metabolism - other enzymes Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬 | [19] 13 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 |
37 |
Fludeoxyglucose
| [1] Fludeoxyglucose Fludeoxyglucose | [1] D01843
D01843
| - | - | [4] 34 34, 84, 85, 88 |
38 |
Fludeoxyglucose (18F)
| [3] 18F-FDG 18F-FDG; Fludeoxyglucose; Fludeoxyglucose F 18 | - | - | - | [14] 5 5, 6, 7, 8, 13, 34, 41, 46, 53, 84, 85, 96, 127, 300 |
39 |
Formoterol
| [2] Formoterol Formoterol; Symbicort | [3] D01373
D01373
,
D05277
,
D07990
| [1] ADRB2 ADRB2 💬 | [9] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [3] 85 85, 228, 299 |
40 |
Fresolimumab
| [2] Fresolimumab Fresolimumab; GC1008 | [1] D09620
D09620
| [3] TGFB1 TGFB1, TGFB2, TGFB3 💬 | [35] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬 | [4] 51 51, 85, 222, 274 |
41 |
Gefapixant
| [1] Gefapixant Gefapixant | [1] D11349
D11349
| [1] P2RX3 P2RX3 💬 | [3] Calcium signaling pathway Calcium signaling pathway, Neuroactive ligand-receptor interaction, Taste transduction 💬 | [2] 85 85, 226 |
42 |
GLPG-1205
| [0] | - | - | - | [3] 85 85, 96, 97 |
43 |
Hydroxyurea
| [1] Hydroxyurea Hydroxyurea | [1] D00341
D00341
| [1] RRM2 RRM2 💬 | [6] Drug metabolism - other enzymes Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬 | [8] 3 3, 13, 19, 20, 65, 85, 86, 284 |
44 |
Ifenprodil
| [1] Ifenprodil Ifenprodil | [1] D08064
D08064
| [3] ADRA1A ADRA1A, ADRA1B, ADRA1D 💬 | [7] AMPK signaling pathway AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 85 85 |
45 |
Iloprost
| [2] Iloprost Iloprost; Ventavis | [1] D02721
D02721
| [1] PTGIR PTGIR 💬 | [3] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [4] 51 51, 84, 85, 86 |
46 |
Imatinib
| [4] Gleevec Gleevec; GLIVEC; Imatinib; Imatinib mesylate | [2] D01441
D01441
,
D08066
| [3] ABL1 ABL1, KIT, PDGFRA 💬 | [32] Acute myeloid leukemia Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬 | [12] 13 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 |
47 |
Infliximab
| [6] Flixabi Flixabi; Inflectra; Infliximab; REMICADE; REMSIMA; Zessly | [1] D02598
D02598
| [1] TNF TNF 💬 | [67] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [27] 35 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 |
48 |
Inosine
| [1] Inosine Inosine | [1] D00054
D00054
| - | - | [6] 2 2, 6, 13, 17, 85, 122 |
49 |
Interferon Gamma
| [1] Interferon Gamma Interferon Gamma | - | - | - | [8] 18 18, 65, 85, 107, 228, 299, 301, 326 |
50 |
Interferon gamma-1b
| [2] ACTIMMUNE ACTIMMUNE; Interferon gamma-1b | [1] D00747
D00747
| [2] IFNGR1 IFNGR1, IFNGR2 💬 | [18] Chagas disease Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬 | [7] 18 18, 65, 85, 228, 299, 301, 326 |
51 |
Interleukin-1 alpha, human recombinant
| [1] None None | - | - | - | [13] 6 6, 46, 51, 65, 84, 85, 96, 97, 140, 161, 231, 271, 299 |
52 |
Lanreotide
| [3] Lanreotide Lanreotide; LANREOTIDE ACETATE; Somatuline Autogel | - | - | - | [4] 67 67, 73, 85, 298 |
53 |
Lansoprazole
| [1] Lansoprazole Lansoprazole | [1] D00355
D00355
| [2] ATP4A ATP4A, ATP4B 💬 | [4] Collecting duct acid secretion Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬 | [7] 63 63, 71, 85, 98, 166, 222, 299 |
54 |
Lebrikizumab
| [1] LEBRIKIZUMAB LEBRIKIZUMAB | [1] D09633
D09633
| [1] IL13 IL13 💬 | [8] Asthma Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬 | [1] 85 85 |
55 |
Letermovir
| [1] Letermovir Letermovir | [1] D10801
D10801
| - | - | [1] 85 85 |
56 |
Levofloxacin
| [2] Levaquin Levaquin; Levofloxacin | [2] D00588
D00588
,
D08120
| - | - | [5] 46 46, 53, 84, 85, 299 |
57 |
Losartan
| [3] Cozaar Cozaar; Losartan; LOSARTAN POTASSIUM | [2] D00357
D00357
,
D08146
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [18] 17 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
58 |
Macitentan
| [2] MACITENTAN MACITENTAN; Opsumit | [1] D10135
D10135
| [2] EDNRA EDNRA, EDNRB 💬 | [9] Calcium signaling pathway Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [5] 51 51, 85, 86, 88, 210 |
59 |
Medical air
| [1] Medical air Medical air | - | - | - | [9] 3 3, 13, 51, 58, 85, 86, 97, 193, 299 |
60 |
Methamidophos
| [1] MONITOR MONITOR | - | - | - | [20] 2 2, 11, 13, 19, 28, 46, 49, 58, 65, 70, 81, 85, 86, 98, 113, 118, 129, 298, 299, 300 |
61 |
Minocycline
| [3] Minocycline Minocycline; MINOCYCLINE HYDROCHLORIDE; Minomycin | [2] D00850
D00850
,
D05045
| - | - | [14] 2 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 |
62 |
Montelukast
| [3] MONTELUKAST MONTELUKAST; MONTELUKAST SODIUM; Singulair | [2] D00529
D00529
,
D08229
| [1] CYSLTR1 CYSLTR1 💬 | [2] Calcium signaling pathway Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬 | [8] 6 6, 13, 46, 61, 63, 85, 98, 228 |
63 |
Morphine
| [2] Morphine Morphine; Morphine Sulfate | [3] D00842
D00842
,
D02271
,
D08233
| [1] OPRM1 OPRM1 💬 | [3] Estrogen signaling pathway Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬 | [6] 36 36, 46, 70, 85, 86, 298 |
64 |
Moxifloxacin
| [2] Moxifloxacin Moxifloxacin; Moxifloxacin Hydrochloride | [2] D00874
D00874
,
D08237
| - | - | [9] 2 2, 6, 46, 49, 85, 86, 113, 240, 299 |
65 |
Mycophenolate mofetil
| [3] CellCept CellCept; Mycophenolate mofetil; Mycophenolate mofetil TEVA | [3] D00752
D00752
,
D05094
,
D05095
| [2] IMPDH1 IMPDH1, IMPDH2 💬 | [3] Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬 | [34] 2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
66 |
Mycophenolic acid
| [5] Acido Micofenolico Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic | [1] D05096
D05096
| [2] IMPDH1 IMPDH1, IMPDH2 💬 | [3] Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬 | [36] 2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
67 |
Nalbuphine
| [2] Nalbuphine Nalbuphine; NALBUPHINE HYDROCHLORIDE | [2] D00843
D00843
,
D08246
| [3] OPRD1 OPRD1, OPRK1, OPRM1 💬 | [5] Estrogen signaling pathway Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬 | [1] 85 85 |
68 |
Nandrolone
| [1] Nandrolone Nandrolone | [1] D08250
D08250
| [1] AR AR 💬 | [4] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬 | [2] 60 60, 85 |
69 |
Nandrolone decanoate
| [1] Nandrolone Decanoate Nandrolone Decanoate | [1] D00955
D00955
| [1] AR AR 💬 | [4] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬 | [2] 60 60, 85 |
70 |
Nebivolol
| [1] Nebivolol Nebivolol | [1] D05127
D05127
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [4] 17 17, 85, 113, 167 |
71 |
Nintedanib
| [2] NINTEDANIB NINTEDANIB; Ofev | [1] D10481
D10481
| [8] FGFR1 FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 | [34] Adherens junction Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬 | [5] 51 51, 85, 89, 227, 228 |
72 |
Nitric Oxide
| [3] INOmax INOmax; NITRIC OXIDE; Nitrosyl | [1] D00074
D00074
| - | - | [16] 6 6, 13, 46, 58, 85, 86, 96, 97, 98, 210, 222, 226, 251, 294, 299, 321 |
73 |
Nivolumab
| [1] Nivolumab Nivolumab | [1] D10316
D10316
| [1] PDCD1 PDCD1 💬 | [3] Cell adhesion molecules Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬 | [12] 13 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 |
74 |
Octreotide
| [3] Octreotide Octreotide; OCTREOTIDE ACETATE; Sandostatin LAR | [2] D00442
D00442
,
D06495
| [1] SSTR2 SSTR2 💬 | [4] Gastric acid secretion Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬 | [7] 67 67, 75, 84, 85, 89, 193, 227 |
75 |
OM85
| [1] Broncho-Vaxom Broncho-Vaxom | - | - | - | [1] 85 85 |
76 |
Omeprazole
| [5] Losec Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM | [4] D00455
D00455
,
D01207
,
D05259
,
D05261
| [2] ATP4A ATP4A, ATP4B 💬 | [4] Collecting duct acid secretion Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬 | [16] 6 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
77 |
Oxygen
| [3] Medical air Medical air; Nitrogen; Oxygen | [1] D00003
D00003
| - | - | [20] 6 6, 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 168, 193, 226, 271, 294, 299, 330 |
78 |
Paclitaxel
| [1] Paclitaxel Paclitaxel | [2] D00491
D00491
,
D05333
| [9] TUBB TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 | [10] Alzheimer disease Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬 | [2] 46 46, 85 |
79 |
Pamrevlumab
| [1] PAMREVLUMAB PAMREVLUMAB | [1] D10969
D10969
| [1] CCN2 CCN2 💬 | [2] Apelin signaling pathway Apelin signaling pathway, Hippo signaling pathway 💬 | [2] 85 85, 113 |
80 |
Paroxetine
| [1] Paroxetine Paroxetine | [4] D02260
D02260
,
D02362
,
D05374
,
D05375
| [1] SLC6A4 SLC6A4 💬 | [2] Serotonergic synapse Serotonergic synapse, Synaptic vesicle cycle 💬 | [4] 6 6, 13, 46, 85 |
81 |
Pirfenidone
| [2] Esbriet Esbriet; Pirfenidone | [1] D01583
D01583
| [6] CCL2 CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 | [84] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [11] 13 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
82 |
Pomalidomide
| [3] Imnovid Imnovid; Pomalidomida; Pomalidomide | [1] D08976
D08976
| [2] IL6 IL6, TNF 💬 | [80] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [6] 28 28, 34, 51, 85, 227, 331 |
83 |
Prednisolone
| [3] Prednisolona Prednisolona; Prednisolone; Prednisolonum | [8] D00472
D00472
,
D00980
,
D00981
,
D00982
,
D01239
,
D01998
,
D02156
,
D03301
| [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [43] 3 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 |
84 |
Prednisone
| [3] Prednisona Prednisona; Prednisone; RAYOS | [1] D00473
D00473
| [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [48] 2 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
85 |
PRM-151
| [1] PRM-151 PRM-151 | - | - | - | [1] 85 85 |
86 |
Quercetin
| [1] Quercetin Quercetin | - | - | - | [5] 84 84, 85, 192, 285, 299 |
87 |
Remestemcel-L
| [3] Adult human mesenchymal stem cells Adult human mesenchymal stem cells; Prochymal; Remestemcel-L | [1] D09719
D09719
| - | - | [3] 85 85, 96, 97 |
88 |
Rituximab
| [6] MABTHERA MABTHERA; Rituxan; RITUXIMAB; Rixathon; Ruxience; Truxima | [1] D02994
D02994
| [1] MS4A1 MS4A1 💬 | [1] Hematopoietic cell lineage Hematopoietic cell lineage 💬 | [49] 6 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 |
89 |
Salbutamol
| [3] Albuterol Albuterol; Salbutamol; Ventolin | [1] D02147
D02147
| [1] ADRB2 ADRB2 💬 | [9] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [14] 3 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 |
90 |
Sildenafil
| [6] Mysildecard Mysildecard; REVATIO; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; Viagra | [2] D02229
D02229
,
D08514
| [1] PDE5A PDE5A 💬 | [3] Metabolic pathways Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬 | [17] 6 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 |
91 |
Simtuzumab
| [2] GS-6624 GS-6624; Simtuzumab | - | - | - | [2] 85 85, 94 |
92 |
Sirolimus
| [3] Rapamune Rapamune; Rapamycin; SIROLIMUS | [1] D00753
D00753
| [1] MTOR MTOR 💬 | [51] AMPK signaling pathway AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬 | [41] 2 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
93 |
Sivelestat
| [1] Sivelestat Sivelestat | [1] D03788
D03788
| [1] ELANE ELANE 💬 | [3] Neutrophil extracellular trap formation Neutrophil extracellular trap formation, Systemic lupus erythematosus, Transcriptional misregulation in cancer 💬 | [3] 13 13, 85, 96 |
94 |
Sulfamethoxazole
| [3] Bactrim Bactrim; Sulfamethoxazole; Sulphamethoxazole | [1] D00447
D00447
| - | - | [5] 44 44, 49, 61, 85, 299 |
95 |
Sulfate ion
| [1] Sulfate Sulfate | - | - | - | [27] 2 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299 |
96 |
Tacrolimus
| [2] Prograf Prograf; Tacrolimus | [2] D00107
D00107
,
D08556
| [5] PPP3CA PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | [33] Alzheimer disease Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬 | [34] 2 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 |
97 |
Taladegib
| [1] Taladegib Taladegib | [1] D10671
D10671
| [1] SMO SMO 💬 | [5] Axon guidance Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬 | [1] 85 85 |
98 |
TD-139
| [0] | - | - | - | [1] 85 85 |
99 |
Tetrandrine
| [1] Tetrandrine Tetrandrine | - | - | - | [2] 46 46, 85 |
100 |
Tetrathiomolybdate
| [1] Tetrathiomolybdate Tetrathiomolybdate | - | - | - | [3] 85 85, 93, 171 |
101 |
Thalidomide
| [1] Thalidomide Thalidomide | [1] D00754
D00754
| [1] TNF TNF 💬 | [67] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [20] 2 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 |
102 |
Thiotepa
| [1] Thiotepa Thiotepa | [1] D00583
D00583
| - | - | [12] 13 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285 |
103 |
Thrombomodulin Alfa
| [1] Thrombomodulin Alfa Thrombomodulin Alfa | [1] D06410
D06410
| [1] F2 F2 💬 | [8] Complement and coagulation cascades Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬 | [1] 85 85 |
104 |
Ticagrelor
| [1] Ticagrelor Ticagrelor | [1] D09017
D09017
| [1] P2RY12 P2RY12 💬 | [1] Platelet activation Platelet activation 💬 | [3] 36 36, 46, 85 |
105 |
Tiotropium
| [3] Spiriva Spiriva; Spiriva Respimat; Tiotropium | - | - | - | [3] 55 55, 85, 299 |
106 |
Tipelukast
| [1] Tipelukast Tipelukast | [1] D06659
D06659
| [1] CYSLTR1 CYSLTR1 💬 | [2] Calcium signaling pathway Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬 | [1] 85 85 |
107 |
Tralokinumab
| [1] Tralokinumab Tralokinumab | [1] D09979
D09979
| [1] IL13 IL13 💬 | [8] Asthma Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬 | [2] 85 85, 97 |
108 |
Treprostinil
| [4] Remodulin Remodulin; Treprostinil; Treprostinilo; Tyvaso | [1] D06213
D06213
| [1] PTGIR PTGIR 💬 | [3] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [6] 51 51, 84, 85, 86, 88, 210 |
109 |
Trimethoprim
| [2] Bactrim Bactrim; Trimethoprim | [2] D00145
D00145
,
D06236
| - | - | [8] 36 36, 44, 49, 60, 61, 85, 298, 299 |
110 |
Valganciclovir
| [1] Valganciclovir Valganciclovir | [1] D02495
D02495
| - | - | [6] 28 28, 60, 85, 97, 299, 331 |
111 |
Valproic acid
| [3] Valproate Valproate; VALPROATE SODIUM; Valproic acid | [1] D00399
D00399
| [7] ABAT ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬 | [17] Alanine, aspartate and glutamate metabolism Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬 | [17] 2 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 |
112 |
Vismodegib
| [2] Erivedge Erivedge; VISMODEGIB | [1] D09992
D09992
| [1] SMO SMO 💬 | [5] Axon guidance Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬 | [1] 85 85 |
113 |
Warfarin
| [2] Warfarin Warfarin; Warfarin Sodium | [3] D00564
D00564
,
D01280
,
D08682
| [2] NQO1 NQO1, VKORC1 💬 | [7] Biosynthesis of cofactors Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬 | [13] 6 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 |
114 |
Xenon
| [1] Xenon Xenon | [2] D01901
D01901
,
D06339
| - | - | [4] 22 22, 85, 228, 299 |
115 |
Zileuton
| [3] Zileuton Zileuton; Zyflo; Zyflo CR | [1] D00414
D00414
| [1] ALOX5 ALOX5 💬 | [6] Arachidonic acid metabolism Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬 | [3] 85 85, 160, 164 |
116 |
Ziritaxestat
| [1] Ziritaxestat Ziritaxestat | [1] D11844
D11844
| [1] ENPP2 ENPP2 💬 | [2] Ether lipid metabolism Ether lipid metabolism, Metabolic pathways 💬 | [2] 51 51, 85 |