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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Alpha-tocotrienolquinone----[1] 18 💬
2Artesunate[1] Artesunate[1] Artesunate 💬--[3] 18, 66, 96 💬
3Artesunate Oral Product[1] Artesunate[1] Artesunate 💬--[1] 18 💬
4Baclofen[1] Baclofen[1] Baclofen 💬[2] GABBR1,
GABBR2 💬
[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[8] 2, 10, 13, 18, 65, 70, 149, 206 💬
5BINOCRIT*1SIR 40000UI/1ML[1] Erythropoietin---[1] 18 💬
6Bupropion[1] Bupropion[1] Bupropion 💬[2] SLC6A2,
SLC6A3 💬
[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171 💬
7Bupropion & Citalopram[2] Bupropion,
Citalopram
[2] Bupropion ,
Citalopram 💬
[3] SLC6A2,
SLC6A3,
SLC6A4 💬
[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 18 💬
8Butylphthalide[1] Butylphthalide---[4] 2, 6, 18, 22 💬
9C-Trelin OD Tab(5mg Taltirelin Hydrate)----[1] 18 💬
10Cabaletta[1] Trehalose---[2] 18, 113 💬
11Cabaletta for IV infusion once weekly during 24 weeks[1] Trehalose---[1] 18 💬
12Calcitriol[1] Calcitriol[1] Calcitriol 💬[1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
13Carbonate[1] Carbonate ion---[12] 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299 💬
14Citalopram[1] Citalopram[1] Citalopram 💬[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
15Coenzyme Q10[1] Ubidecarenone[1] Ubidecarenone 💬--[11] 2, 5, 6, 8, 10, 18, 46, 57, 113, 214, 215 💬
16CTI-1601[1] CTI-1601---[1] 18 💬
17DEFERIPRONE[1] Deferiprone[1] Deferiprone 💬--[6] 2, 6, 18, 120, 122, 233 💬
18DT-216----[1] 18 💬
19EGB 761 (r) 120 mg----[1] 18 💬
20EGb 761 120 mg----[1] 18 💬
21Epoeitin beta----[1] 18 💬
22Epoetin alfa[1] Erythropoietin---[3] 13, 18, 46 💬
23EPREX*1FL 40000UI/ML 1ML----[1] 18 💬
24EPREX*1SIR 10000UI 1ML----[1] 18 💬
25EPREX*1SIR 40000UI/ML 1ML----[2] 2, 18 💬
26ERYTHROPOIETIN[1] Erythropoietin---[9] 2, 6, 13, 18, 22, 47, 70, 95, 96 💬
27ETRAVIRINA[1] Etravirine[1] Etravirine 💬--[1] 18 💬
28Etravirine[1] Etravirine[1] Etravirine 💬--[1] 18 💬
29Etravirine Tablets[1] Etravirine[1] Etravirine 💬--[1] 18 💬
30EU1/97/031-032----[1] 18 💬
31EU1/97/031/031-032----[1] 18 💬
32Flumazenil[1] Flumazenil[1] Flumazenil 💬[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
33Gamma interferon----[1] 18 💬
34Ginkgo[1] Ginkgo biloba---[5] 6, 13, 18, 47, 90 💬
35Ginkgo biloba[1] Ginkgo biloba---[4] 13, 18, 47, 90 💬
36Glentek 50 mg compresse rivestite con film----[1] 18 💬
37Glentek 50 mg film-coated tablets----[1] 18 💬
38Granocyte----[2] 18, 57 💬
39H-116PI-DE.pdf----[1] 18 💬
40High Dose LX2006----[1] 18 💬
41High-dose intravenous immunoglobulin (IVIG)----[1] 18 💬
42Idebenone[1] Idebenone[1] Idebenone 💬--[6] 6, 8, 13, 18, 113, 302 💬
43Imukin----[3] 18, 58, 228 💬
44IMUKIN - 6 FLACONI 0.5 ML 100 MCG----[2] 18, 58 💬
45IMUKIN*SC 6F 0,5ML 100MCG----[1] 18 💬
46INTELENCE[1] Etravirine[1] Etravirine 💬--[1] 18 💬
47INTELENCE - 200 MG - COMPRESSA -USO ORALE - FLACONE (HDPE) 60 COMPRESSE[1] Etravirine[1] Etravirine 💬--[1] 18 💬
48Interferon Gamma[1] Interferon Gamma---[8] 18, 65, 85, 107, 228, 299, 301, 326 💬
49INTERFERON GAMMA-1B[2] Interferon Gamma,
Interferon gamma-1b
[1] Interferon gamma-1b 💬[2] IFNGR1,
IFNGR2 💬
[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326 💬
50Iron[1] Iron---[6] 18, 96, 97, 238, 254, 284 💬
51Iron chelating intervention[1] Iron---[1] 18 💬
52J05AG04----[1] 18 💬
53KPS-0373----[1] 18 💬
54KPS-0373, High dose----[1] 18 💬
55KPS-0373, Low dose----[1] 18 💬
56Lenograstim[1] Lenograstim[1] Lenograstim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65 💬
57LITHIUM CARBONATE[3] Carbonate ion,
Lithium carbonate,
Lithium citrate
[2] Lithium carbonate ,
Lithium citrate 💬
--[5] 2, 13, 17, 18, 127 💬
58Low dose LX2006----[1] 18 💬
59Lu AA24493----[1] 18 💬
60Methylprednisolone[1] Methylprednisolone[1] Methylprednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
61MIB-626----[1] 18 💬
62MIN-102----[2] 18, 20 💬
63Neo-Recormon----[1] 18 💬
64NeoRecormon[1] Erythropoietin---[2] 13, 18 💬
65Nicotinamide[1] Nicotinamide[1] Niacinamide 💬--[8] 2, 6, 18, 49, 97, 107, 162, 191 💬
66Nicotinamide riboside[2] Nicotinamide,
Nicotinamide riboside
[1] Niacinamide 💬--[5] 2, 6, 18, 97, 191 💬
67Omaveloxolone[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
68Omaveloxolone Capsules, 10 mg[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
69Omaveloxolone Capsules, 150 mg[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
70Omaveloxolone Capsules, 160 mg[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
71Omaveloxolone Capsules, 2.5 mg[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
72Omaveloxolone Capsules, 20 mg[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
73Omaveloxolone Capsules, 300 mg[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
74Omaveloxolone Capsules, 40 mg[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
75Omaveloxolone Capsules, 5 mg[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
76Omaveloxolone Capsules, 80 mg[1] Omaveloxolone[1] Omaveloxolone 💬[1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
77PTC743----[2] 18, 21 💬
78Resveratrol[1] Resveratrol---[6] 2, 8, 18, 89, 97, 113 💬
79RHuG-CSF----[1] 18 💬
80RILUZOLE[1] Riluzole[1] Riluzole 💬[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
81Riluzole PMCS[1] Riluzole[1] Riluzole 💬[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[1] 18 💬
82RILUZOLO----[3] 2, 18, 114 💬
83Rokan (r) Novo 120 mg----[1] 18 💬
84Rosuvastatin[1] Rosuvastatin[1] Rosuvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
85Standardized Ginkgo Biloba Extract (EGb 761 (r)[1] Ginkgo biloba---[1] 18 💬
86SUB09246MIG----[1] 18 💬
87TAK-831[1] TAK-831---[1] 18 💬
88VARENICLINE[1] Varenicline[1] Varenicline 💬[2] CHRNA4,
CHRNB2 💬
[4] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[3] 6, 18, 53 💬
89VATIQUINONE[1] Vatiquinone[1] Vatiquinone 💬--[2] 18, 21 💬