Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Amitriptyline, fluoxetine and tramadol alone (control group)
(D08623)		[3] Amitriptyline,
Fluoxetine,
Tramadol		[3] Fluoxetine ,
Amitriptyline ,
Tramadol (D08623) 💬		[3] OPRM1,
SLC6A2,
SLC6A4 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 78 💬
2Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group)
(D08623)		[4] Amitriptyline,
Fluoxetine,
Somatotropin,
Tramadol		[3] Fluoxetine ,
Amitriptyline ,
Tramadol (D08623) 💬		[3] OPRM1,
SLC6A2,
SLC6A4 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 78 💬
3Tramadol
(D08623)		[1] Tramadol[1] Tramadol (D08623) 💬[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271 💬
4Tramadol /acetaminophen
(D08623)		[2] Acetaminophen,
Tramadol		[2] Acetaminophen ,
Tramadol (D08623) 💬		[3] OPRM1,
PTGS1,
PTGS2 💬		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Estrogen signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 271 💬
5Tramadol hydrochloride + acetaminophen
(D08623)		[2] Acetaminophen,
Tramadol		[2] Acetaminophen ,
Tramadol (D08623) 💬		[3] OPRM1,
PTGS1,
PTGS2 💬		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Estrogen signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46 💬
6Tramadol with ropivacaine
(D08623)		[2] Ropivacaine,
Tramadol		[2] Ropivacaine ,
Tramadol (D08623) 💬		[6] OPRM1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[6] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction 💬[1] 70 💬