Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Platelet activation 💬
[1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬 💬
2 Platelet activation 💬
[1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬 💬
3 Platelet activation 💬
[1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬 💬
4 Platelet activation 💬
[1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬 💬
5 Platelet activation 💬
[1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬 💬
6 Platelet activation 💬
[1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬 💬
7 Platelet activation 💬
[1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬 💬
8 Platelet activation 💬
[1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬 💬
9 Platelet activation 💬
[1] F2 💬 Dabigatran 💬 Dabigatran [5] 51, 75, 85, 91, 124 💬 💬
10 Platelet activation 💬
[1] F2 💬 Dabigatran etexilate 💬 Dabigatran etexilate [2] 51, 75 💬 💬
11 Platelet activation 💬
[1] F2 💬 Thrombomodulin alfa 💬 Thrombomodulin Alfa [1] 85 💬 💬
12 Platelet activation 💬
[2] FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
13 Platelet activation 💬
[2] FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
14 Platelet activation 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Amyl nitrite 💬 Amyl Nitrite [1] 58 💬 💬
15 Platelet activation 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬 💬
16 Platelet activation 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
17 Platelet activation 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
18 Platelet activation 💬
[1] P2RY12 💬 Clopidogrel 💬 Clopidogrel [3] 49, 51, 86 💬 💬
19 Platelet activation 💬
[1] P2RY12 💬 Clopidogrel hydrochloride 💬 Clopidogrel [3] 49, 51, 86 💬 💬
20 Platelet activation 💬
[1] P2RY12 💬 Clopidogrel besilate 💬 Clopidogrel [3] 49, 51, 86 💬 💬
21 Platelet activation 💬
[1] P2RY12 💬 Ticagrelor 💬 Ticagrelor [3] 36, 46, 85 💬 💬
22 Platelet activation 💬
[1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
23 Platelet activation 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
24 Platelet activation 💬
[1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
25 Platelet activation 💬
[1] PTGIR 💬 Beraprost 💬 Beraprost [1] 86 💬 💬
26 Platelet activation 💬
[1] PTGIR 💬 Epoprostenol 💬 Epoprostenol [1] 86 💬 💬
27 Platelet activation 💬
[1] PTGIR 💬 Ibudilast 💬 Ibudilast [2]  2 , 13 💬 💬
28 Platelet activation 💬
[1] PTGIR 💬 Iloprost 💬 Iloprost [4] 51, 84, 85, 86 💬 💬
29 Platelet activation 💬
[1] PTGIR 💬 Ralinepag 💬 Ralinepag [1] 86 💬 💬
30 Platelet activation 💬
[1] PTGIR 💬 Selexipag 💬 Selexipag [5] 51, 70, 84, 86, 88 💬 💬
31 Platelet activation 💬
[1] PTGIR 💬 Treprostinil 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬 💬
32 Platelet activation 💬
[1] PTGS1 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬 💬
33 Platelet activation 💬
[1] PTGS1 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
34 Platelet activation 💬
[1] PTGS1 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
35 Platelet activation 💬
[1] PTGS1 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬 💬
36 Platelet activation 💬
[1] PTGS1 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬 💬
37 Platelet activation 💬
[1] PTGS1 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬 💬
38 Platelet activation 💬
[1] PTGS1 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬 💬
39 Platelet activation 💬
[1] PTGS1 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬 💬
40 Platelet activation 💬
[1] PTGS1 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬 💬
41 Platelet activation 💬
[1] PTGS1 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬 💬
42 Platelet activation 💬
[1] PTGS1 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬 💬
43 Platelet activation 💬
[1] PTGS1 💬 Salsalate 💬 Salsalate [1]  5  💬 💬
44 Platelet activation 💬
[1] PTGS1 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
45 Platelet activation 💬
[1] PTGS1 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬 💬
46 Platelet activation 💬
[2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬 💬
47 Platelet activation 💬
[1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬 💬
48 Platelet activation 💬
[1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬 💬
49 Platelet activation 💬
[1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬 💬
50 Platelet activation 💬
[1] SYK 💬 Fostamatinib 💬 Fostamatinib [4] 46, 49, 61, 66 💬 💬
51 Platelet activation 💬
[1] TBXA2R 💬 Cilostazol 💬 Cilostazol [3] 46, 51, 70 💬 💬
52 Platelet activation 💬
[1] TBXA2R 💬 Ifetroban 💬 Ifetroban [2] 85, 113 💬 💬
53 Platelet activation 💬
[1] TBXA2R 💬 Ramatroban 💬 Ramatroban [1] 13 💬 💬
54 Platelet activation 💬
[1] VWF 💬 Caplacizumab 💬 Caplacizumab [1] 64 💬 💬