Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Non-small cell lung cancer 💬
 [1] ALK 💬 Brigatinib 💬 Brigatinib [1] 34 💬 💬
2 Non-small cell lung cancer 💬
 [1] ALK 💬 Crizotinib 💬 Crizotinib [1] 34 💬 💬
3 Non-small cell lung cancer 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬 💬
4 Non-small cell lung cancer 💬
 [3] BRAF, RAF1, RET 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
5 Non-small cell lung cancer 💬
 [1] CASP9 💬 Rimiducid 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬 💬
6 Non-small cell lung cancer 💬
 [2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬 💬
7 Non-small cell lung cancer 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬 💬
8 Non-small cell lung cancer 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬 💬
9 Non-small cell lung cancer 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬 💬
10 Non-small cell lung cancer 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬 💬
11 Non-small cell lung cancer 💬
 [2] EGFR, ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬 💬
12 Non-small cell lung cancer 💬
 [2] EGFR, ERBB2 💬 Neratinib 💬 Neratinib [1] 34 💬 💬
13 Non-small cell lung cancer 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬 💬
14 Non-small cell lung cancer 💬
 [1] JAK3 💬 Peficitinib 💬 Peficitinib [1] 46 💬 💬
15 Non-small cell lung cancer 💬
 [1] JAK3 💬 Tofacitinib 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
16 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
17 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
18 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
19 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
20 Non-small cell lung cancer 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
21 Non-small cell lung cancer 💬
 [1] MET 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬 💬
22 Non-small cell lung cancer 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
23 Non-small cell lung cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
24 Non-small cell lung cancer 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
25 Non-small cell lung cancer 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬 💬
26 Non-small cell lung cancer 💬
 [1] RARB 💬 Fenretinide 💬 Fenretinide [1] 299 💬 💬
27 Non-small cell lung cancer 💬
 [1] RARB 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬 💬
28 Non-small cell lung cancer 💬
 [1] RARB 💬 Tretinoin 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬 💬
29 Non-small cell lung cancer 💬
 [1] RARB 💬 Vitamin A 💬 Vitamin A [3] 13, 53, 90 💬 💬
30 Non-small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬 💬
31 Non-small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬 💬
32 Non-small cell lung cancer 💬
 [1] RET 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬 💬
33 Non-small cell lung cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬 💬
34 Small cell lung cancer 💬
 [1] BCL2 💬 Venetoclax 💬 Venetoclax [1] 28 💬 💬
35 Small cell lung cancer 💬
 [1] CASP9 💬 Rimiducid 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬 💬
36 Small cell lung cancer 💬
 [2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬 💬
37 Small cell lung cancer 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬 💬
38 Small cell lung cancer 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
39 Small cell lung cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
40 Small cell lung cancer 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
41 Small cell lung cancer 💬
 [1] PTGS2 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬 💬
42 Small cell lung cancer 💬
 [1] PTGS2 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
43 Small cell lung cancer 💬
 [1] PTGS2 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
44 Small cell lung cancer 💬
 [1] PTGS2 💬 Celecoxib 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬
45 Small cell lung cancer 💬
 [1] PTGS2 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬 💬
46 Small cell lung cancer 💬
 [1] PTGS2 💬 Diflunisal 💬 Diflunisal [1] 28 💬 💬
47 Small cell lung cancer 💬
 [1] PTGS2 💬 Etodolac 💬 Etodolac [1] 46 💬 💬
48 Small cell lung cancer 💬
 [1] PTGS2 💬 Etoricoxib 💬 Etoricoxib [2] 46, 271 💬 💬
49 Small cell lung cancer 💬
 [1] PTGS2 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬 💬
50 Small cell lung cancer 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬 💬
51 Small cell lung cancer 💬
 [1] PTGS2 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬 💬
52 Small cell lung cancer 💬
 [1] PTGS2 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬 💬
53 Small cell lung cancer 💬
 [1] PTGS2 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬 💬
54 Small cell lung cancer 💬
 [1] PTGS2 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬 💬
55 Small cell lung cancer 💬
 [1] PTGS2 💬 Lumiracoxib 💬 Lumiracoxib [1] 46 💬 💬
56 Small cell lung cancer 💬
 [1] PTGS2 💬 Meloxicam 💬 Meloxicam [4] 46, 49, 271, 296 💬 💬
57 Small cell lung cancer 💬
 [1] PTGS2 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬 💬
58 Small cell lung cancer 💬
 [1] PTGS2 💬 Nimesulide 💬 Nimesulide [1] 46 💬 💬
59 Small cell lung cancer 💬
 [1] PTGS2 💬 Parecoxib 💬 Parecoxib [2] 46, 271 💬 💬
60 Small cell lung cancer 💬
 [1] PTGS2 💬 Rofecoxib 💬 Rofecoxib [1] 46 💬 💬
61 Small cell lung cancer 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬 💬
62 Small cell lung cancer 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
63 Small cell lung cancer 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬 💬
64 Small cell lung cancer 💬
 [1] PTGS2 💬 Valdecoxib 💬 Valdecoxib [1] 46 💬 💬
65 Small cell lung cancer 💬
 [1] RARB 💬 Fenretinide 💬 Fenretinide [1] 299 💬 💬
66 Small cell lung cancer 💬
 [1] RARB 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬 💬
67 Small cell lung cancer 💬
 [1] RARB 💬 Tretinoin 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬 💬
68 Small cell lung cancer 💬
 [1] RARB 💬 Vitamin A 💬 Vitamin A [3] 13, 53, 90 💬 💬
69 Small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin [1] 37 💬 💬
70 Small cell lung cancer 💬
 [4] RARB, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin [1] 49 💬 💬
71 Small cell lung cancer 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬 💬
72 Small cell lung cancer 💬
 [3] RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene [2] 13, 75 💬 💬

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