Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Dalfampridine [7] 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; FAMPYRA[1] Dalfampridine 💬[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14 💬
2 Dexmedetomidine [4] Dexdor; DEXMEDETOMIDINA; DEXMEDETOMIDINE; DEXMEDETOMIDINE HYDROCHLORIDE[1] Dexmedetomidine 💬[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
3 Esketamine [3] ESKETAMINE; KETAMINE; S-ketamine[1] Esketamine 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[3] 2, 4, 70 💬
4 Ketamine [2] KETAMINE; NMDA[1] Ketamine 💬[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 4, 6, 13, 70, 113, 156, 215 💬
5 Levetiracetam [2] KEPPRA; Levetiracetam[1] Levetiracetam 💬[1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307 💬
6 Pyrimethamine [2] Daraprim; Pyrimethamine[1] Pyrimethamine 💬--[12] 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265 💬