Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CTSC 💬 [2] Lysosome, Apoptosis Brensocatib 💬 Brensocatib [1] 299 💬
2 TPP1 💬 [1] Lysosome Cerliponase alfa 💬 Cerliponase alfa [1] 19 💬
3 GAA 💬 [4] Galactose metabolism, Starch and sucrose metabolism, Metabolic pathways, Lysosome Acarbose 💬 Acarbose [1] 298 💬
4 GAA 💬 [4] Galactose metabolism, Starch and sucrose metabolism, Metabolic pathways, Lysosome Alglucosidase alfa 💬 Alglucosidase alfa [1] 256 💬
5 GAA 💬 [4] Galactose metabolism, Starch and sucrose metabolism, Metabolic pathways, Lysosome Duvoglustat 💬 Duvoglustat [1] 256 💬
6 GAA 💬 [4] Galactose metabolism, Starch and sucrose metabolism, Metabolic pathways, Lysosome Avalglucosidase alfa 💬 Avalglucosidase alfa [1] 256 💬
7 GAA 💬 [4] Galactose metabolism, Starch and sucrose metabolism, Metabolic pathways, Lysosome Cipaglucosidase alfa 💬 Cipaglucosidase alfa [1] 256 💬
8 GALNS 💬 [3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome Elosulfase alfa 💬 Elosulfase alfa [1] 19 💬
9 GBA1 💬 [4] Other glycan degradation, Sphingolipid metabolism, Metabolic pathways, Lysosome Alglucerase 💬 Alglucerase [1] 19 💬
10 GBA1 💬 [4] Other glycan degradation, Sphingolipid metabolism, Metabolic pathways, Lysosome Imiglucerase 💬 Imiglucerase [1] 19 💬
11 GBA1 💬 [4] Other glycan degradation, Sphingolipid metabolism, Metabolic pathways, Lysosome Velaglucerase alfa 💬 Velaglucerase alfa [1] 19 💬
12 GBA1 💬 [4] Other glycan degradation, Sphingolipid metabolism, Metabolic pathways, Lysosome Taliglucerase alfa 💬 Taliglucerase alfa [1] 19 💬
13 GLA 💬 [6] Galactose metabolism, Glycerolipid metabolism, Sphingolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Metabolic pathways, Lysosome Agalsidase alfa 💬 Agalsidase alfa [1] 19 💬
14 GLA 💬 [6] Galactose metabolism, Glycerolipid metabolism, Sphingolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Metabolic pathways, Lysosome Agalsidase beta 💬 Agalsidase beta [1] 19 💬
15 GUSB 💬 [8] Pentose and glucuronate interconversions, Ascorbate and aldarate metabolism, Glycosaminoglycan degradation, Porphyrin metabolism, Drug metabolism - other enzymes, Metabolic pathways, Biosynthesis of cofactors, Lysosome Vestronidase alfa 💬 Vestronidase alfa [1] 19 💬
16 IDS 💬 [3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome Idursulfase 💬 Idursulfase [1] 19 💬
17 IDS 💬 [3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome Idursulfase beta 💬 Idursulfase beta [1] 19 💬
18 IDS 💬 [3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome Pabinafusp alfa 💬 Pabinafusp alfa [1] 19 💬
19 IDUA 💬 [3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome Laronidase 💬 Laronidase [2] 19, 256 💬
20 LIPA 💬 [3] Steroid biosynthesis, Lysosome, Cholesterol metabolism Sebelipase alfa 💬 Sebelipase alfa [1] 19 💬
21 ARSB 💬 [3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome Galsulfase 💬 Galsulfase [1] 19 💬
22 MAN2B1 💬 [2] Other glycan degradation, Lysosome Velmanase alfa 💬 Velmanase alfa [1] 19 💬
23 SORT1 💬 [3] Lysosome, Neurotrophin signaling pathway, Cholesterol metabolism Latozinemab 💬 Latozinemab [2] 2, 127 💬
24 SMPD1 💬 [5] Sphingolipid metabolism, Metabolic pathways, Sphingolipid signaling pathway, Lysosome, Necroptosis Olipudase alfa 💬 Olipudase alfa [1] 19 💬