Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ABCD1 💬 [2] ABC transporters, Peroxisome Elivaldogene autotemcel 💬 Elivaldogene autotemcel [1] 20 💬
2 HAO1 💬 [4] Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Carbon metabolism, Peroxisome Lumasiran 💬 Lumasiran [1] 234 💬
3 SOD1 💬 [8] Peroxisome, Longevity regulating pathway - multiple species, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species Tofersen 💬 Tofersen [1] 2 💬
4 XDH 💬 [6] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome Allopurinol 💬 Allopurinol [7] 6, 46, 57, 60, 66, 96, 97 💬
5 XDH 💬 [6] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome Febuxostat 💬 Febuxostat [3] 2, 6, 13 💬