Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
Vorinostat Vorinostat 💬 |
Vorinostat | 075 [2] 75, 96 💬 💬 |
2 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
3 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
4 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
5 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
INSR [1] INSR 💬 |
Insulin detemir Insulin detemir 💬 |
Insulin detemir | 299 [1] 299 💬 💬 |
6 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
INSR [1] INSR 💬 |
Insulin glargine Insulin glargine 💬 |
Insulin glargine | 299 [1] 299 💬 💬 |
7 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
INSR [1] INSR 💬 |
Insulin human Insulin human 💬 |
Insulin human | 096 [2] 96, 156 💬 💬 |
8 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
9 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
10 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
11 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
12 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
13 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
14 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
15 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
SOD1 [1] SOD1 💬 |
Tofersen Tofersen 💬 |
Tofersen | 002 [1] 2 💬 💬 |