Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
CACNA1C [5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
3 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
4 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
5 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
6 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
7 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
8 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
9 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
10 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
CACNA1C [6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
11 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
12 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
DRD1 [1] DRD1 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
13 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 [2] GRIA1, GRIA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
14 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
SIGMAR1 [1] SIGMAR1 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
15 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
16 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
17 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
CA2 [1] CA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
18 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
19 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
20 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
DRD1 [2] DRD1, DRD5 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
21 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [2] HTR2A, HTR2C 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
22 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
23 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
24 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
25 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
HTR1D [1] HTR1D 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
26 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
27 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D [1] CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
28 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
29 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
30 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
31 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D [1] CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
32 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
33 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
34 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
35 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
36 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
37 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
38 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
39 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C [6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
40 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
41 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
42 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [1] GRIA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
43 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
CA2 [1] CA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
44 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
45 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
46 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
47 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
48 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
49 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
50 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
51 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
CACNA1C [7] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
52 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
53 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
54 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
55 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
CACNA1C [20] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
56 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Clobazam Clobazam 💬 |
Clobazam | 140 [2] 140, 144 💬 💬 |
57 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
58 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
HTR2A [2] HTR2A, HTR2C 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
59 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
CA2 [1] CA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
60 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
61 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
CACNA1C [11] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
62 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
63 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
64 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
65 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
66 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
67 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
68 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
69 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
70 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
71 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
HTR2A [2] HTR2A, HTR2C 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
72 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
73 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
74 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
75 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
CACNA1C [1] CACNA1C 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
76 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
CACNA1C [3] CACNA1C, GRIA1, GRIA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
77 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
78 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
79 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CA2 [2] CA2, CA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
80 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
81 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
DRD1 [1] DRD1 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
82 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Clobazam Clobazam 💬 |
Clobazam | 140 [2] 140, 144 💬 💬 |
83 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
84 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 [2] CNR1, CNR2 💬 |
Cannabidiol Cannabidiol 💬 |
Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬 |
85 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
86 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Clobazam Clobazam 💬 |
Clobazam | 140 [2] 140, 144 💬 💬 |
87 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [25] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
88 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
HTR1D [3] HTR1D, HTR2A, HTR2C 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
89 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Clobazam Clobazam 💬 |
Clobazam | 140 [2] 140, 144 💬 💬 |
90 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [20] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
91 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 18 diseases |
CA2 [2] CA2, CA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
92 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
93 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
94 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CA2 [1] CA2 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
95 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD1 [2] DRD1, DRD2 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
96 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
97 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
98 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SIGMAR1 [1] SIGMAR1 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
99 | Phenylalanine metabolism 💬 6 genes, 12 drugs (DrugBank) and 15 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
100 | Primary bile acid biosynthesis 💬 1 gene, 1 drug (DrugBank) and 2 diseases |
CYP46A1 [1] CYP46A1 💬 |
Soticlestat Soticlestat 💬 |
Soticlestat | 140 [2] 140, 144 💬 💬 |
101 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
102 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
103 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 19 diseases |
CA2 [2] CA2, CA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
104 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CNR1 [1] CNR1 💬 |
Cannabidiol Cannabidiol 💬 |
Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬 |
105 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬 |
Levodopa Levodopa 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 💬 |
106 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
107 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
108 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
109 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
CACNA1C [24] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
110 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
CNR1 [1] CNR1 💬 |
Cannabidiol Cannabidiol 💬 |
Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬 |
111 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Clobazam Clobazam 💬 |
Clobazam | 140 [2] 140, 144 💬 💬 |
112 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
113 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
114 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
115 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
Clobazam Clobazam 💬 |
Clobazam | 140 [2] 140, 144 💬 💬 |
116 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR1D [4] HTR1D, HTR2A, HTR2C, SLC6A4 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
117 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
118 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
119 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
CACNA1C [1] CACNA1C 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
120 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
CACNA1C [10] CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
121 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
Clobazam Clobazam 💬 |
Clobazam | 140 [2] 140, 144 💬 💬 |
122 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
HTR1D [1] HTR1D 💬 |
Fenfluramine Fenfluramine 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 💬 |
123 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬 |
Cannabidiol Cannabidiol 💬 |
Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬 |
124 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
CACNA1D [1] CACNA1D 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
125 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
CACNA1D [1] CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
126 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
GRIA3 [1] GRIA3 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
127 | Tryptophan metabolism 💬 5 genes, 10 drugs (DrugBank) and 12 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
128 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
129 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
130 | Tyrosine metabolism 💬 10 genes, 16 drugs (DrugBank) and 18 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
131 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
132 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |