Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
2 Alcoholic liver disease 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
3 Alcoholism 💬
 [1] DRD2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
4 Alcoholism 💬
 [1] DRD2 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
5 Alcoholism 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
6 Alcoholism 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
7 Alcoholism 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
8 Alcoholism 💬
 [1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬 💬
9 Alzheimer disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
10 Alzheimer disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
11 Alzheimer disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
12 Alzheimer disease 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
13 Amphetamine addiction 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
14 Amphetamine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
15 Amphetamine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
16 Amphetamine addiction 💬
 [1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬 💬
17 AMPK signaling pathway 💬
 [1] HMGCR 💬 Lovastatin 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬
18 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
19 Amyotrophic lateral sclerosis 💬
 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
20 Amyotrophic lateral sclerosis 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
21 Amyotrophic lateral sclerosis 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
22 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
23 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
24 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
25 Bile secretion 💬
 [1] HMGCR 💬 Lovastatin 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬
26 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
27 Calcium signaling pathway 💬
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
28 Calcium signaling pathway 💬
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
29 Calcium signaling pathway 💬
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
30 Calcium signaling pathway 💬
 [1] HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
31 Calcium signaling pathway 💬
 [1] HTR2A 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
32 Calcium signaling pathway 💬
 [1] OXTR 💬 Oxytocin 💬 Oxytocin [7]  6 , 72, 127, 168, 193, 206, 226 💬 💬
33 cAMP signaling pathway 💬
 [1] DRD2 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
34 cAMP signaling pathway 💬
 [2] DRD2, HTR1A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
35 cAMP signaling pathway 💬
 [2] GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen [2] 13, 206 💬 💬
36 cAMP signaling pathway 💬
 [2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
37 cAMP signaling pathway 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
38 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
39 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
40 cAMP signaling pathway 💬
 [1] OXTR 💬 Oxytocin 💬 Oxytocin [7]  6 , 72, 127, 168, 193, 206, 226 💬 💬
41 cAMP signaling pathway 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬 💬
42 cAMP signaling pathway 💬
 [1] PDE4D 💬 Zatolmilast 💬 Zatolmilast [1] 206 💬 💬
43 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
44 Cholinergic synapse 💬
 [1] ACHE 💬 Donepezil 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬 💬
45 Circadian entrainment 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
46 Circadian entrainment 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
47 Circadian entrainment 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
48 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
49 Cocaine addiction 💬
 [1] DRD2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
50 Cocaine addiction 💬
 [1] DRD2 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
51 Cocaine addiction 💬
 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
52 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
53 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
54 Cocaine addiction 💬
 [1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬 💬
55 Dopaminergic synapse 💬
 [1] DRD2 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
56 Dopaminergic synapse 💬
 [2] DRD2, DRD3 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
57 Dopaminergic synapse 💬
 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
58 Dopaminergic synapse 💬
 [2] GRIN2A, GRIN2B 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
59 Dopaminergic synapse 💬
 [2] GRIN2A, GRIN2B 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
60 Dopaminergic synapse 💬
 [1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬 💬
61 Estrogen signaling pathway 💬
 [2] GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen [2] 13, 206 💬 💬
62 Estrogen signaling pathway 💬
 [2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
63 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
64 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
65 GABAergic synapse 💬
 [2] GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen [2] 13, 206 💬 💬
66 GABAergic synapse 💬
 [2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
67 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Flumazenil 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬 💬
68 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬 💬
69 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬 💬
70 Gap junction 💬
 [2] DRD2, HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
71 Gap junction 💬
 [2] DRD2, HTR2A 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
72 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
73 Glutamatergic synapse 💬
 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
74 Glutamatergic synapse 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
75 Glutamatergic synapse 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
76 Glycerophospholipid metabolism 💬
 [1] ACHE 💬 Donepezil 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬 💬
77 GnRH secretion 💬
 [2] GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen [2] 13, 206 💬 💬
78 GnRH secretion 💬
 [2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
79 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
80 Human papillomavirus infection 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
81 Huntington disease 💬
 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
82 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
83 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
84 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
85 IL-17 signaling pathway 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
86 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
87 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
88 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
89 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
90 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
91 Leishmaniasis 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
92 Long-term depression 💬
 [3] GRIA1, GRIA2, GRIA3 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
93 Long-term potentiation 💬
 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
94 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
95 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
96 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
97 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
98 Metabolic pathways 💬
 [1] HMGCR 💬 Lovastatin 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬
99 Metabolic pathways 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬 💬
100 Metabolic pathways 💬
 [1] PDE4D 💬 Zatolmilast 💬 Zatolmilast [1] 206 💬 💬
101 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
102 MicroRNAs in cancer 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
103 Morphine addiction 💬
 [2] GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen [2] 13, 206 💬 💬
104 Morphine addiction 💬
 [2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
105 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Flumazenil 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬 💬
106 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬 💬
107 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬 💬
108 Morphine addiction 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬 💬
109 Morphine addiction 💬
 [1] PDE4D 💬 Zatolmilast 💬 Zatolmilast [1] 206 💬 💬
110 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
111 Neuroactive ligand-receptor interaction 💬
 [2] CNR1, CNR2 💬 Cannabidiol 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬
112 Neuroactive ligand-receptor interaction 💬
 [4] DRD2, DRD3, HTR1A, HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
113 Neuroactive ligand-receptor interaction 💬
 [2] DRD2, HTR2A 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
114 Neuroactive ligand-receptor interaction 💬
 [2] GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen [2] 13, 206 💬 💬
115 Neuroactive ligand-receptor interaction 💬
 [2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
116 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Flumazenil 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬 💬
117 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬 💬
118 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬 💬
119 Neuroactive ligand-receptor interaction 💬
 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
120 Neuroactive ligand-receptor interaction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
121 Neuroactive ligand-receptor interaction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
122 Neuroactive ligand-receptor interaction 💬
 [1] OXTR 💬 Oxytocin 💬 Oxytocin [7]  6 , 72, 127, 168, 193, 206, 226 💬 💬
123 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
124 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Flumazenil 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬 💬
125 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬 💬
126 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬 💬
127 Nicotine addiction 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
128 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
129 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
130 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
131 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
132 Oxytocin signaling pathway 💬
 [1] OXTR 💬 Oxytocin 💬 Oxytocin [7]  6 , 72, 127, 168, 193, 206, 226 💬 💬
133 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
134 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
135 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬 💬
136 Parathyroid hormone synthesis, secretion and action 💬
 [1] PDE4D 💬 Zatolmilast 💬 Zatolmilast [1] 206 💬 💬
137 Parkinson disease 💬
 [1] DRD2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
138 Parkinson disease 💬
 [1] DRD2 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
139 Parkinson disease 💬
 [1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬 💬
140 Pathways in cancer 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
141 Pathways of neurodegeneration - multiple diseases 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
142 Pathways of neurodegeneration - multiple diseases 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
143 Pathways of neurodegeneration - multiple diseases 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
144 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
145 Pathways of neurodegeneration - multiple diseases 💬
 [1] SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬 💬
146 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
147 Platelet activation 💬
 [1] PTGS1 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
148 Prion disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
149 Prion disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
150 Prion disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
151 Purine metabolism 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬 💬
152 Purine metabolism 💬
 [1] PDE4D 💬 Zatolmilast 💬 Zatolmilast [1] 206 💬 💬
153 Rap1 signaling pathway 💬
 [1] CNR1 💬 Cannabidiol 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬
154 Rap1 signaling pathway 💬
 [1] DRD2 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
155 Rap1 signaling pathway 💬
 [1] DRD2 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
156 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
157 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
158 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
159 Ras signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
160 Ras signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
161 Ras signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
162 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
163 Retrograde endocannabinoid signaling 💬
 [1] CNR1 💬 Cannabidiol 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬
164 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Flumazenil 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬 💬
165 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬 💬
166 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬 💬
167 Retrograde endocannabinoid signaling 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
168 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
169 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 Flumazenil 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬 💬
170 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬 💬
171 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬 💬
172 Serotonergic synapse 💬
 [2] HTR1A, HTR2A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
173 Serotonergic synapse 💬
 [1] HTR2A 💬 Risperidone 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬 💬
174 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
175 Serotonergic synapse 💬
 [1] SLC6A4 💬 Fluoxetine 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬 💬
176 Serotonergic synapse 💬
 [1] SLC6A4 💬 Sertraline 💬 Sertraline [2]  6 , 206 💬 💬
177 Small cell lung cancer 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
178 Spinocerebellar ataxia 💬
 [8] GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
179 Spinocerebellar ataxia 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
180 Spinocerebellar ataxia 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
181 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A3 💬 Methylphenidate 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬 💬
182 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Fluoxetine 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬 💬
183 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Sertraline 💬 Sertraline [2]  6 , 206 💬 💬
184 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬 💬
185 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
186 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
187 Taste transduction 💬
 [2] GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen [2] 13, 206 💬 💬
188 Taste transduction 💬
 [2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
189 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Flumazenil 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬 💬
190 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬 💬
191 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬 💬
192 Taste transduction 💬
 [1] HTR1A 💬 Aripiprazole 💬 Aripiprazole [2]  6 , 206 💬 💬
193 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 Lovastatin 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬
194 Thermogenesis 💬
 [1] CNR1 💬 Cannabidiol 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬
195 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
196 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
197 TNF signaling pathway 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
198 Transcriptional misregulation in cancer 💬
 [1] GRIA3 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
199 VEGF signaling pathway 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬

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