Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 mTOR signaling pathway 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
2 mTOR signaling pathway 💬
 [2] BRAF, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
3 mTOR signaling pathway 💬
 [1] IGF1R 💬 Linsitinib 💬 Linsitinib [1] 232 💬
4 mTOR signaling pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
5 mTOR signaling pathway 💬
 [1] IGF1R 💬 Teprotumumab 💬 Teprotumumab [1] 51 💬
6 mTOR signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
7 mTOR signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
8 mTOR signaling pathway 💬
 [1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
9 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
10 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
11 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
12 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
13 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
14 mTOR signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
15 mTOR signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
16 mTOR signaling pathway 💬
 [1] MTOR 💬 Temsirolimus 💬 Temsirolimus [1] 13 💬
17 mTOR signaling pathway 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
18 mTOR signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
19 mTOR signaling pathway 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
20 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
21 mTOR signaling pathway 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
22 mTOR signaling pathway 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
23 mTOR signaling pathway 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
24 mTOR signaling pathway 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
25 mTOR signaling pathway 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
26 mTOR signaling pathway 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
27 mTOR signaling pathway 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
28 mTOR signaling pathway 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬
29 mTOR signaling pathway 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬
30 mTOR signaling pathway 💬
 [1] TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
31 mTOR signaling pathway 💬
 [1] TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
32 mTOR signaling pathway 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬