Target Gene/Pathway Pathway / Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Tight junction 💬

[1] CACNA1D 💬

Amlodipine 💬

[4] 13, 51, 67, 298 💬

2

Tight junction 💬

[1] CACNA1D 💬

Cilnidipine 💬

[1] 67 💬

3

Tight junction 💬

[1] CACNA1D 💬

[3] 51, 58, 86 💬

4

Tight junction 💬

[1] CACNA1D 💬

Isradipine 💬

[1] 6 💬

5

Tight junction 💬

[1] CACNA1D 💬

Nicardipine 💬

[2] 70, 86 💬

6

Tight junction 💬

[1] CACNA1D 💬

Nifedipine 💬

[2] 50, 81 💬

7

Tight junction 💬

[1] CACNA1D 💬

Nilvadipine 💬

[1] 90 💬

8

Tight junction 💬

[1] CACNA1D 💬

Perhexiline 💬

[2] 58, 272 💬

9

Tight junction 💬

[1] CACNA1D 💬

Propiverine 💬

[1] 226 💬

10

Tight junction 💬

[1] CACNA1D 💬

Topiramate 💬

[6] 6 , 97, 140, 144, 156, 193 💬

11

Tight junction 💬

[1] CACNA1D 💬

[4] 58, 96, 140, 167 💬

12

Tight junction 💬

[1] CDK4 💬

Abemaciclib 💬

[1] 34 💬

13

Tight junction 💬

[1] CFTR 💬

Deutivacaftor 💬

[1] 299 💬

14

Tight junction 💬

[1] CFTR 💬

Elexacaftor 💬

[1] 299 💬

15

Tight junction 💬

[1] CFTR 💬

Galicaftor 💬

[1] 299 💬

16

Tight junction 💬

[1] CFTR 💬

[1] 299 💬

17

Tight junction 💬

[1] CFTR 💬

Lumacaftor 💬

[1] 299 💬

18

Tight junction 💬

[1] CFTR 💬

Tezacaftor 💬

[1] 299 💬

19

Tight junction 💬

[1] ERBB2 💬

[3] 34, 74, 75 💬

20

Tight junction 💬

[1] ERBB2 💬

[1] 34 💬

21

Tight junction 💬

[1] ERBB2 💬

Tesevatinib 💬

[1] 67 💬

22

Tight junction 💬

[1] MAP3K5 💬

Selonsertib 💬

[1] 86 💬

23

Tight junction 💬

[2] PRKAA1, PRKAA2 💬

[25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
60	Aplastic anemia;
65	Primary immunodeficiency;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
75	Cushing disease;Cushing;
77	Growth hormone secreting pituitary adenoma;Pituitary growth hormone secretion hyperthyroidism;
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;
86	Pulmonary arterial hypertension;PAH;
97	Ulcerative colitis;
113	Muscular dystrophy;
127	Frontotemporal lobar degeneration;
158	Tuberous sclerosis;Tuberous sclerosis complex;
206	Fragile X syndrome;
218	Alport syndrome;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;
265	Lipodystrophy;
285	Fanconi anemia;
299	Cystic fibrosis;
301	Macular dystrophy;

24

Tight junction 💬

[1] PRKCE 💬

Sotrastaurin 💬

[1] 97 💬

25

Tight junction 💬

[2] ROCK1, ROCK2 💬

[4] 2 , 5 , 7 , 51 💬

26

Tight junction 💬

[1] ROCK2 💬

Belumosudil 💬

[2] 51, 85 💬

27

Tight junction 💬

[1] SRC 💬

[2] 2 , 67 💬

28

Tight junction 💬

[1] SRC 💬

[2] 51, 85 💬

29

Tight junction 💬

[1] SRC 💬

[2] 51, 85 💬

30

Tight junction 💬

[1] SRC 💬

Saracatinib 💬

[3] 6 , 89, 272 💬