Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 C-type lectin receptor signaling pathway 💬
 [4] IL10, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
2 C-type lectin receptor signaling pathway 💬
 [3] IL12A, IL12B, IL23A 💬 Ustekinumab 💬 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬
3 C-type lectin receptor signaling pathway 💬
 [1] IL1B 💬 Canakinumab 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
4 C-type lectin receptor signaling pathway 💬
 [1] IL1B 💬 Gevokizumab 💬 Gevokizumab [4] 41, 50, 56, 269 💬 💬
5 C-type lectin receptor signaling pathway 💬
 [1] IL1B 💬 Rilonacept 💬 Rilonacept [4] 51, 106, 107, 266 💬 💬
6 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 Brazikumab 💬 Brazikumab [2] 96, 97 💬 💬
7 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 Guselkumab 💬 Guselkumab [5] 37, 41, 51, 96, 97 💬 💬
8 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 Mirikizumab 💬 Mirikizumab [3] 37, 96, 97 💬 💬
9 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 Risankizumab 💬 Risankizumab [4] 37, 96, 97, 271 💬 💬
10 C-type lectin receptor signaling pathway 💬
 [1] IL23A 💬 Tildrakizumab 💬 Tildrakizumab [2] 162, 271 💬 💬
11 C-type lectin receptor signaling pathway 💬
 [1] IL6 💬 Olokizumab 💬 Olokizumab [2] 46, 96 💬 💬
12 C-type lectin receptor signaling pathway 💬
 [1] IL6 💬 Siltuximab 💬 Siltuximab [2] 28, 331 💬 💬
13 C-type lectin receptor signaling pathway 💬
 [1] IL6 💬 Sirukumab 💬 Sirukumab [2] 41, 46 💬 💬
14 C-type lectin receptor signaling pathway 💬
 [2] IL6, TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬 💬
15 C-type lectin receptor signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
16 C-type lectin receptor signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
17 C-type lectin receptor signaling pathway 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬 💬
18 C-type lectin receptor signaling pathway 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
19 C-type lectin receptor signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
20 C-type lectin receptor signaling pathway 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
21 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬
22 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus [1] 160 💬 💬
23 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
24 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
25 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin [2] 49, 222 💬 💬
26 C-type lectin receptor signaling pathway 💬
 [1] PRKCD 💬 Sotrastaurin 💬 Sotrastaurin [1] 97 💬 💬
27 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬 💬
28 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
29 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
30 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Celecoxib 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬
31 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬 💬
32 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Diflunisal 💬 Diflunisal [1] 28 💬 💬
33 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Etodolac 💬 Etodolac [1] 46 💬 💬
34 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Etoricoxib 💬 Etoricoxib [2] 46, 271 💬 💬
35 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬 💬
36 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬 💬
37 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬 💬
38 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬 💬
39 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬 💬
40 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬 💬
41 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Lumiracoxib 💬 Lumiracoxib [1] 46 💬 💬
42 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Meloxicam 💬 Meloxicam [4] 46, 49, 271, 296 💬 💬
43 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬 💬
44 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Nimesulide 💬 Nimesulide [1] 46 💬 💬
45 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Parecoxib 💬 Parecoxib [2] 46, 271 💬 💬
46 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Rofecoxib 💬 Rofecoxib [1] 46 💬 💬
47 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬 💬
48 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬 💬
49 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬 💬
50 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Valdecoxib 💬 Valdecoxib [1] 46 💬 💬
51 C-type lectin receptor signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
52 C-type lectin receptor signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬 💬
53 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬 💬
54 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
55 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
56 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬 💬
57 C-type lectin receptor signaling pathway 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [4] 46, 49, 61, 66 💬 💬
58 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
59 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
60 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
61 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
62 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
63 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
64 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬 💬
65 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬 💬
66 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬