Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
2 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
CSF2 [1] CSF2 💬 |
Otilimab Otilimab 💬 |
Otilimab | 046 [1] 46 💬 💬 |
3 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IFNG [1] IFNG 💬 |
Emapalumab Emapalumab 💬 |
Emapalumab | 049 [3] 49, 65, 107 💬 💬 |
4 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IFNG [1] IFNG 💬 |
Fontolizumab Fontolizumab 💬 |
Fontolizumab | 046 [1] 46 💬 💬 |
5 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL13 [1] IL13 💬 |
Anrukinzumab Anrukinzumab 💬 |
Anrukinzumab | 097 [1] 97 💬 💬 |
6 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL13 [1] IL13 💬 |
Lebrikizumab Lebrikizumab 💬 |
Lebrikizumab | 085 [1] 85 💬 💬 |
7 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL13 [1] IL13 💬 |
Tralokinumab Tralokinumab 💬 |
Tralokinumab | 085 [2] 85, 97 💬 💬 |
8 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL17A [1] IL17A 💬 |
Ixekizumab Ixekizumab 💬 |
Ixekizumab | 036 [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 💬 |
9 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL17A [1] IL17A 💬 |
Secukinumab Secukinumab 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 💬 |
10 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL17A [1] IL17A 💬 |
Tibulizumab Tibulizumab 💬 |
Tibulizumab | 053 [1] 53 💬 💬 |
11 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL17A [2] IL17A, IL17F 💬 |
Bimekizumab Bimekizumab 💬 |
Bimekizumab | 046 [3] 46, 97, 271 💬 💬 |
12 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL17RA [1] IL17RA 💬 |
Brodalumab Brodalumab 💬 |
Brodalumab | 037 [2] 37, 51 💬 💬 |
13 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B [1] IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
14 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B [1] IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 💬 |
15 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B [1] IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 💬 |
16 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL4 [1] IL4 💬 |
Binetrakin Binetrakin 💬 |
Binetrakin | 046 [1] 46 💬 💬 |
17 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL5 [1] IL5 💬 |
Mepolizumab Mepolizumab 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 💬 |
18 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL5 [1] IL5 💬 |
Reslizumab Reslizumab 💬 |
Reslizumab | 044 [2] 44, 98 💬 💬 |
19 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL6 [1] IL6 💬 |
Olokizumab Olokizumab 💬 |
Olokizumab | 046 [2] 46, 96 💬 💬 |
20 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL6 [1] IL6 💬 |
Siltuximab Siltuximab 💬 |
Siltuximab | 028 [2] 28, 331 💬 💬 |
21 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL6 [1] IL6 💬 |
Sirukumab Sirukumab 💬 |
Sirukumab | 041 [2] 41, 46 💬 💬 |
22 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL6 [2] IL6, TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
23 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Losmapimod Losmapimod 💬 |
Losmapimod | 113 [2] 113, 222 💬 💬 |
24 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
Neflamapimod Neflamapimod 💬 |
Neflamapimod | 008 [1] 8 💬 💬 |
25 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
MMP13 [1] MMP13 💬 |
Apratastat Apratastat 💬 |
Apratastat | 046 [1] 46 💬 💬 |
26 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
NFKB1 [1] NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 💬 |
27 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 [1] 46 💬 💬 |
28 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
29 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
30 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
31 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 💬 |
32 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Diflunisal Diflunisal 💬 |
Diflunisal | 028 [1] 28 💬 💬 |
33 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Etodolac Etodolac 💬 |
Etodolac | 046 [1] 46 💬 💬 |
34 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Etoricoxib Etoricoxib 💬 |
Etoricoxib | 046 [2] 46, 271 💬 💬 |
35 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 💬 |
36 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 💬 |
37 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 💬 |
38 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 [1] 46 💬 💬 |
39 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 [2] 70, 226 💬 💬 |
40 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 [2] 46, 271 💬 💬 |
41 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Lumiracoxib Lumiracoxib 💬 |
Lumiracoxib | 046 [1] 46 💬 💬 |
42 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Meloxicam Meloxicam 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 💬 |
43 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 💬 |
44 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Nimesulide Nimesulide 💬 |
Nimesulide | 046 [1] 46 💬 💬 |
45 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Parecoxib Parecoxib 💬 |
Parecoxib | 046 [2] 46, 271 💬 💬 |
46 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Rofecoxib Rofecoxib 💬 |
Rofecoxib | 046 [1] 46 💬 💬 |
47 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 [1] 5 💬 💬 |
48 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 [1] 206 💬 💬 |
49 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 [1] 5 💬 💬 |
50 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Valdecoxib Valdecoxib 💬 |
Valdecoxib | 046 [1] 46 💬 💬 |
51 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
RELA [1] RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 [1] 113 💬 💬 |
52 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
53 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
54 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
55 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
56 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
57 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
58 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
59 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
60 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |