79. Homozygous familial hypercholesterolemia Disease details / Clinical trials / Drug dev / DR info

Clinical trials : 145 /  Drugs : 114 - (DrugBank : 26) / Drug target genes : 8 - Drug target pathways : 17

Homozygous familial hypercholesterolemia and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability
IDDiseases (Sorted by drug repositionability)
79Homozygous familial hypercholesterolemia
93Primary biliary cholangitis
316Carnitine cycle disorder
288Autoimmune acquired coagulation factor deficiency
94Primary sclerosing cholangitis
271Ankylosing spondylitis
222Primary nephrotic syndrome
84Sarcoidosis
299Cystic fibrosis
51Scleroderma
49Systemic lupus erythematosus
97Ulcerative colitis
46Malignant rheumatoid arthritis
13Multiple sclerosis/Neuromyelitis optica
324Methylglutaconic aciduria
317Trifunctional protein deficiency
260Sitosterolemia
220Rapidly progressive glomerulonephritis
30Distal myopathy