Granocyte ( DrugBank: - )


2 diseases
告示番号疾患名(ページ内リンク)臨床試験数
18脊髄小脳変性症(多系統萎縮症を除く。)1
57特発性拡張型心筋症2

18. 脊髄小脳変性症(多系統萎縮症を除く。)


臨床試験数 : 71 薬物数 : 101 - (DrugBank : 30) / 標的遺伝子数 : 45 - 標的パスウェイ数 : 65
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2017-003084-34-GB
(EUCTR)
22/01/201828/11/2017Testing granulocyte-colony stimulating factor (GCSF) in patients with Friedreich AtaxiaThe pharmacological effects of granulocyte-colony stimulating factor (GCSF) on frataxin expression in patients with Friedreich Ataxia - GCSF for Friedreich Ataxia Friedreich Ataxia
MedDRA version: 20.0;Level: LLT;Classification code 10003592;Term: Ataxia cerebellar;System Organ Class: 100000004852
MedDRA version: 20.0;Level: PT;Classification code 10017374;Term: Friedreich's ataxia;System Organ Class: 10010331 - Congenital, familial and genetic disorders ;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]
Trade Name: Granocyte
Product Name: Granocyte
INN or Proposed INN: rHuG-CSF
Other descriptive name: Lenograstim
University of BristolNULLNot Recruiting Female:
Male:
7 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): noUnited Kingdom

57. 特発性拡張型心筋症


臨床試験数 : 12 薬物数 : 25 - (DrugBank : 12) / 標的遺伝子数 : 9 - 標的パスウェイ数 : 34
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01302171
(ClinicalTrials.gov)
August 201021/2/2011Bone Marrow Derived Adult Stem Cells for Dilated CardiomyopathyRandomised Controlled Trial to Compare the Effects of G-CSF (Granocyte™) and Autologous Bone Marrow Progenitor Cells on Quality of Life and Left Ventricular Function in Patients With Idiopathic Dilated CardiomyopathyDilated CardiomyopathyDrug: granulocyte colony stimulating factor (GCSF);Procedure: bone marrow mononuclear cellsBarts & The London NHS TrustRoyal Brompton & Harefield NHS Foundation Trust;University College London HospitalsCompleted18 Years80 YearsBoth60Phase 2United Kingdom
2EUCTR2009-013112-12-GB
(EUCTR)
22/04/201017/03/2010Randomised Controlled Trial To Compare The effects of G-CSF(Granocyte™) And Autologous Bone Marrow Progenitor Cells On Quality Of Life And Left Ventricular Function In Patients with Idiopathic Dilated Cardiomyopathy - REGENERATE-DCMRandomised Controlled Trial To Compare The effects of G-CSF(Granocyte™) And Autologous Bone Marrow Progenitor Cells On Quality Of Life And Left Ventricular Function In Patients with Idiopathic Dilated Cardiomyopathy - REGENERATE-DCM Idiopathic Dilated Cardiomyopathy
Level: LLTClassification code 10056419Term: Dilated Cardiomyopathy
Trade Name: Granocyte Lenograstim
Product Name: GRANOCYTE - 34 million IU (Lenograstim rHuG-CSF)
Product Code: PL 12185/0002 & PL 12185/0005(WATER FOR INJECTION)
Barts & the London NHS TrustNULLNot RecruitingFemale: yes
Male: yes
United Kingdom