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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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11 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  cAMP signaling pathway 
 2 genes, 1 drug (DrugBank) and 5 diseases shown 
 2件: GABBR1, GABBR2   D00241   Baclofen   5件: 2, 10, 13, 18, 149 
 2  Cholinergic synapse 
 2 genes, 1 drug (DrugBank) and 2 diseases shown 
 2件: CHRNA4, CHRNB2   D08669   Varenicline   2件: 6, 18 
 3  Estrogen signaling pathway 
 2 genes, 1 drug (DrugBank) and 5 diseases shown 
 2件: GABBR1, GABBR2   D00241   Baclofen   5件: 2, 10, 13, 18, 149 
 4  GABAergic synapse 
 18 genes, 2 drugs (DrugBank) and 8 diseases shown 
 2件: GABBR1, GABBR2   D00241   Baclofen   5件: 2, 10, 13, 18, 149 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   5件: 6, 13, 17, 18, 206 
 5  GnRH secretion 
 2 genes, 1 drug (DrugBank) and 5 diseases shown 
 2件: GABBR1, GABBR2   D00241   Baclofen   5件: 2, 10, 13, 18, 149 
 6  Morphine addiction 
 18 genes, 2 drugs (DrugBank) and 8 diseases shown 
 2件: GABBR1, GABBR2   D00241   Baclofen   5件: 2, 10, 13, 18, 149 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   5件: 6, 13, 17, 18, 206 
 7  Neuroactive ligand-receptor interaction 
 20 genes, 3 drugs (DrugBank) and 8 diseases shown 
 2件: CHRNA4, CHRNB2   D08669   Varenicline   2件: 6, 18 
 2件: GABBR1, GABBR2   D00241   Baclofen   5件: 2, 10, 13, 18, 149 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   5件: 6, 13, 17, 18, 206 
 8  Nicotine addiction 
 18 genes, 2 drugs (DrugBank) and 5 diseases shown 
 2件: CHRNA4, CHRNB2   D08669   Varenicline   2件: 6, 18 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   5件: 6, 13, 17, 18, 206 
 9  Retrograde endocannabinoid signaling 
 16 genes, 1 drug (DrugBank) and 5 diseases shown 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   5件: 6, 13, 17, 18, 206 
 10  Serotonergic synapse 
 3 genes, 1 drug (DrugBank) and 5 diseases shown 
 3件: GABRB1, GABRB2, GABRB3   D00697   Flumazenil   5件: 6, 13, 17, 18, 206 
 11  Taste transduction 
 8 genes, 2 drugs (DrugBank) and 8 diseases shown 
 2件: GABBR1, GABBR2   D00241   Baclofen   5件: 2, 10, 13, 18, 149 
 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D00697   Flumazenil   5件: 6, 13, 17, 18, 206 

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