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No. 薬物名(臨床試験情報から抽出) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1[Glentek 50 mg compresse rivestite con film]----1件: 18
2[J05AG04]1件: Etravirine1件: D04112 --1件: 18
3[PTC743]1件: Vatiquinone1件: D10407 --2件: 18, 21
4Alpha-tocotrienolquinone1件: Vatiquinone1件: D10407 --1件: 18
5Artesunate1件: Artesunate1件: D02482 --3件: 18, 66, 96
6Artesunate Oral Product1件: Artesunate1件: D02482 --1件: 18
7Baclofen1件: Botulinum toxin type A1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬7件: 2, 10, 13, 18, 65, 149, 206
8BINOCRIT*1SIR 40000UI/1ML1件: Erythropoietin1件: D03231 1件: EPOR 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬1件: 18
9Bupropion1件: Bupropion3件: D00817 ,
D07591 ,
D07938
2件: SLC6A2,
SLC6A3 💬
7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬5件: 8, 18, 21, 96, 171
10Bupropion & Citalopram1件: Citalopram2件: D00822 ,
D07704
1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬1件: 18
11Butylphthalide1件: Butylphthalide---4件: 2, 6, 18, 22
12C-Trelin OD Tab(5mg Taltirelin Hydrate)----1件: 18
13Cabaletta1件: Trehalose---2件: 18, 113
14Cabaletta for IV infusion once weekly during 24 weeks1件: Trehalose---1件: 18
15Calcitriol1件: Calcitriol1件: D00129 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬9件: 18, 37, 46, 49, 66, 96, 158, 235, 326
16Carbonate1件: Calcitriol1件: D00129 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬12件: 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299
17Citalopram1件: Citalopram2件: D00822 ,
D07704
1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
18Coenzyme Q101件: Ubidecarenone1件: D01065 --12件: 2, 5, 6, 8, 10, 18, 46, 57, 113, 193, 214, 215
19CTI-1601----1件: 18
20DEFERIPRONE1件: Deferiprone1件: D07416 --6件: 2, 6, 18, 120, 122, 233
21Diagnostic Test: Blood analysis for hypercalcemia's control1件: Calcitriol1件: D00129 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬1件: 18
22DT-216----1件: 18
23EGB 761 (r) 120 mg1件: Ginkgo biloba---1件: 18
24EGb 761 120 mg----1件: 18
25Epoeitin beta----1件: 18
26Epoetin alfa1件: Erythropoietin1件: D03231 1件: EPOR 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬3件: 13, 18, 46
27EPREX*1FL 40000UI/ML 1ML1件: Erythropoietin1件: D03231 1件: EPOR 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬1件: 18
28EPREX*1SIR 10000UI 1ML1件: Erythropoietin1件: D03231 1件: EPOR 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬1件: 18
29EPREX*1SIR 40000UI/ML 1ML1件: Erythropoietin1件: D03231 1件: EPOR 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬2件: 2, 18
30ERYTHROPOIETIN1件: Erythropoietin1件: D03231 1件: EPOR 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬9件: 2, 6, 13, 18, 22, 47, 70, 95, 96
31ETRAVIRINA1件: Etravirine1件: D04112 --1件: 18
32Etravirine1件: Etravirine1件: D04112 --1件: 18
33Etravirine Tablets1件: Etravirine1件: D04112 --1件: 18
34EU1/97/031-032----1件: 18
35EU1/97/031/031-032----1件: 18
36Flumazenil1件: Flumazenil1件: D00697 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 13, 17, 18, 206
37Gamma interferon----1件: 18
38Ginkgo1件: Ginkgo biloba---5件: 6, 13, 18, 47, 90
39Ginkgo biloba1件: Ginkgo biloba---4件: 13, 18, 47, 90
40Glentek 50 mg compresse rivestite con film----1件: 18
41Glentek 50 mg film-coated tablets----1件: 18
42Granocyte1件: Lenograstim1件: D03247 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬2件: 18, 57
43H-116PI-DE.pdf----1件: 18
44High-dose intravenous immunoglobulin (IVIG)----1件: 18
45Idebenone1件: Idebenone1件: D01750 --6件: 6, 8, 13, 18, 113, 302
46Imukin----3件: 18, 58, 228
47IMUKIN - 6 FLACONI 0.5 ML 100 MCG----2件: 18, 58
48IMUKIN*SC 6F 0,5ML 100MCG1件: Interferon gamma-1b1件: D00747 2件: IFNGR1,
IFNGR2 💬
18件: Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬1件: 18
49INTELENCE1件: Etravirine1件: D04112 --1件: 18
50INTELENCE - 200 MG - COMPRESSA -USO ORALE - FLACONE (HDPE) 60 COMPRESSE1件: Etravirine1件: D04112 --1件: 18
51Interferon Gamma1件: Interferon Gamma---8件: 18, 65, 85, 107, 228, 299, 301, 326
52INTERFERON GAMMA-1B1件: Interferon gamma-1b1件: D00747 2件: IFNGR1,
IFNGR2 💬
18件: Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬7件: 18, 65, 85, 228, 299, 301, 326
53Iron1件: Iron---6件: 18, 96, 97, 238, 254, 284
54Iron chelating intervention1件: Iron---1件: 18
55KPS-0373----1件: 18
56KPS-0373, High dose----1件: 18
57KPS-0373, Low dose----1件: 18
58Lenograstim1件: Pantoprazole2件: D02593 ,
D05353
2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 2, 13, 16, 18, 19, 57, 65
59LITHIUM CARBONATE1件: Lithium carbonate1件: D00801 --6件: 2, 13, 17, 18, 19, 127
60Lu AA24493----1件: 18
61Methylprednisolone1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
62MIB-626----1件: 18
63MIN-102----2件: 18, 20
64Neo-Recormon----1件: 18
65NeoRecormon----2件: 13, 18
66Nicotinamide1件: Nicotinamide1件: D00036 --8件: 2, 6, 18, 49, 65, 107, 162, 191
67Nicotinamide riboside1件: Nicotinamide1件: D00036 --4件: 2, 6, 18, 191
68Omaveloxolone1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
69Omaveloxolone Capsules, 10 mg1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
70Omaveloxolone Capsules, 150 mg1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
71Omaveloxolone Capsules, 160 mg1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
72Omaveloxolone Capsules, 2.5 mg1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
73Omaveloxolone Capsules, 20 mg1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
74Omaveloxolone Capsules, 300 mg1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
75Omaveloxolone Capsules, 40 mg1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
76Omaveloxolone Capsules, 5 mg1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
77Omaveloxolone Capsules, 80 mg1件: Omaveloxolone1件: D10964 1件: NFE2L2 💬7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18
78Other: Blood analysis for frataxin's level measurement1件: Calcitriol1件: D00129 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬1件: 18
79Other: Exercise intervention1件: Alanine1件: D00012 --2件: 13, 18
80PTC7431件: Vatiquinone1件: D10407 --2件: 18, 21
81Resveratrol1件: Resveratrol---6件: 2, 8, 18, 89, 113, 299
82RHuG-CSF1件: Lenograstim1件: D03247 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬1件: 18
83RILUZOLE1件: Riluzole1件: D00775 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
84Riluzole PMCS1件: Riluzole1件: D00775 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬1件: 18
85RILUZOLO----3件: 2, 18, 114
86Rokan (r) Novo 120 mg1件: Ginkgo biloba---1件: 18
87Rosuvastatin1件: Rosuvastatin2件: D01915 ,
D08492
1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
88Standardized Ginkgo Biloba Extract (EGb 761 (r)1件: Ginkgo biloba---1件: 18
89SUB09246MIG1件: Nicotinamide1件: D00036 --1件: 18
90TAK-8311件: TAK-831---1件: 18
91VARENICLINE1件: Varenicline1件: D08669 2件: CHRNA4,
CHRNB2 💬
4件: Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬2件: 6, 18
92VATIQUINONE1件: Vatiquinone1件: D10407 --2件: 18, 21