Drug Description in Trials / DrugBank / KEGG DRUG


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No. KEGG DRUG DrugBank 薬物名(臨床試験情報から抽出) KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Mannitol
(Synonym: ARIDOL BRONCHIAL CHALLENGE TEST KIT)
1件: Mannitol (Synonym: TERUFLEX Blood Bag System with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose Red Cell Preservative)4件: Aridol; Bronchitol; Mannite; Mannitol; --7件: 6, 13, 28, 60, 96, 113, 299
2 Testosterone 1件: Testosterone1件: Testosterone; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬8件: 1, 2, 3, 13, 60, 76, 78, 113
3 Hydrocortisone
(Synonym: TEXACORT)
1件: Hydrocortisone (Synonym: Harris Teeter Anti-Itch Intensive Healing)6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
4 Tetracycline 1件: Tetracycline2件: Tetracyclin; Tetracycline; --5件: 13, 36, 46, 53, 97
5 Atenolol
(Synonym: Tenormin (TN))
1件: Atenolol (Synonym: Tenormin)1件: ATENOLOL; 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 167
6 Carbamazepine
(Synonym: Tegretol (TN))
1件: Carbamazepine (Synonym: Tegretol CR)1件: Carbamazepine; 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 6, 13, 231
7 Cosyntropin
(Synonym: Tetracosactide (INN))
1件: Tetracosactide4件: Cosyntropin; Synacthen Depot; Tetracosactide; Tetracosactrin; 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 78, 83, 113, 145, 222
8 Dronabinol
(Synonym: Tetrahydrocannabinol)
1件: Dronabinol (Synonym: delta-tetrahydrocannabinol)4件: DELTA-9-TETRAHYDROCANNABINOL; DRONABINOL; SATIVEX; Tetrahydrocannabinol; 2件: CNR1,
CNR2 💬
4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬8件: 2, 8, 13, 36, 46, 96, 271, 298
9 Isoflurane
(Synonym: TERRELL)
1件: Isoflurane (Synonym: Terrell)1件: Isoflurane; --1件: 6
10 Thiotepa
(Synonym: Tepadina (TN))
1件: Thiotepa (Synonym: Tepadina)1件: Thiotepa; --12件: 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
11 Telmisartan 1件: Telmisartan1件: Telmisartan; 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 67
12 Metoclopramide
(Synonym: Terperan (TN))
1件: Metoclopramide1件: METOCLOPRAMIDE; 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 46, 51
13 Calcium citrate
(Synonym: Calcium citrate tetrahydrate)
1件: Calcium citrate1件: Calcium citrate; --3件: 46, 84, 235
14 Testosterone enanthate 1件: Testosterone enanthate1件: Testosterone Enanthate; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113
15 Testosterone propionate 1件: Testosterone propionate1件: Testosterone propionate; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113
16 Tegafur 1件: Tegafur0件: 1件: TYMS 💬5件: Antifolate resistance, Metabolic pathways, Nucleotide metabolism, One carbon pool by folate, Pyrimidine metabolism 💬1件: 46
17 Terguride 1件: Terguride1件: Terguride; 2件: DRD2,
PRL 💬
12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 51, 86
18 Teicoplanin 1件: Teicoplanin1件: Teicoplanin; --2件: 70, 299
19 Terbinafine 1件: Terbinafine1件: Terbinafine; --3件: 96, 97, 271
20 Magnesium citrate
(Synonym: Tectlol (TN))
1件: Magnesium citrate1件: Magnesium citrate; --1件: 97
21 Dimethyl fumarate
(Synonym: Tecfidera (TN))
1件: Dimethyl fumarate (Synonym: Teva-dimethyl Fumarate)3件: Dimethyl fumarate; Dimethylfumarat; TECFIDERA; 1件: KEAP1 💬6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬5件: 13, 49, 51, 86, 296
22 Erythrityl tetranitrate 1件: Erythrityl tetranitrate0件: 2件: NPR1,
NPR2 💬
10件: Aldosterone synthesis and secretion, Metabolic pathways, Oxytocin signaling pathway, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 46
23 Teduglutide 1件: Teduglutide1件: Teduglutide; 1件: GLP2R 💬1件: Neuroactive ligand-receptor interaction 💬1件: 96
24 Tefibazumab 1件: Tefibazumab1件: Tefibazumab; --1件: 299
25 Temozolomide 1件: Temozolomide1件: Temozolomide; --1件: 34
26 Temsirolimus 1件: Temsirolimus1件: Temsirolimus; 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬1件: 13
27 Tenofovir 1件: Tenofovir1件: Tenofovir; --6件: 2, 13, 25, 93, 265, 325
28 Teriparatide 1件: Teriparatide4件: Forsteo; Forteo; PTH 1-34; Teriparatide; 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬7件: 46, 65, 68, 70, 71, 235, 274
29 Testosterone undecanoate 1件: Testosterone undecanoate1件: Testosterone undecanoate; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 13, 60
30 Tesamorelin 1件: Tesamorelin2件: GHRH; Tesamorelin; 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 78, 265
31 Terlipressin 1件: Terlipressin1件: TERLIPRESSIN; 3件: AVPR1A,
AVPR1B,
AVPR2 💬
5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬1件: 299
32 Sodium tetradecyl sulfate 1件: Sodium tetradecyl sulfate0件: --2件: 50, 51
33 Green tea leaf 1件: Green tea leaf4件: Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract; --4件: 6, 17, 28, 46
34 Buprenorphine
(Synonym: Temgesic (TN))
1件: Buprenorphine (Synonym: Teva-buprenorphine/naloxone)1件: Buprenorphine; 2件: OPRK1,
OPRM1 💬
3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬2件: 46, 70
35 Fexofenadine
(Synonym: Telfast (TN))
1件: Fexofenadine (Synonym: Terfenadine-COOH)1件: Fexofenadine; 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬2件: 13, 46
36 Ketamine
(Synonym: Tekam (TN))
1件: Ketamine2件: Ketamine; NMDA; 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 4, 6, 13, 70, 113, 156, 215
37 Terazosin 1件: Terazosin1件: Terazosin; 3件: ADRA1A,
ADRA1B,
ADRA1D 💬
7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6
38 Terbutaline 1件: Terbutaline1件: Terbutaline; 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 118
39 Testosterone decanoate 1件: Testosterone decanoate1件: Testosterone decanoate; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113
40 Testosterone phenylpropionate 1件: Testosterone phenylpropionate1件: Testosterone phenylpropionate; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113
41 Tetrabenazine 1件: Tetrabenazine2件: Tetrabenazine; Xenazine; 1件: SLC18A2 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 8
42 Vincristine
(Synonym: Tecnocris (TN))
1件: Vincristine2件: Vincristine; Vincristine Sulfate; 9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬
10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬4件: 26, 34, 65, 331
43 Ceftaroline fosamil
(Synonym: Teflaro (TN))
1件: Ceftaroline fosamil (Synonym: Teflaro)1件: Ceftaroline; --1件: 299
44 Teprotumumab 1件: Teprotumumab1件: TEPEZZA; 1件: IGF1R 💬29件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, HIF-1 signaling pathway, Hepatocellular carcinoma, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬1件: 51
45 Tedizolid 1件: Tedizolid1件: Tedizolid; --1件: 299
46 Telotristat 1件: Telotristat1件: Telotristat; 2件: TPH1,
TPH2 💬
4件: Folate biosynthesis, Metabolic pathways, Serotonergic synapse, Tryptophan metabolism 💬1件: 97
47 Teriflunomide 1件: Teriflunomide2件: AUBAGIO; Teriflunomide; 1件: DHODH 💬3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬3件: 13, 25, 26
48 Tenofovir alafenamide 1件: Tenofovir alafenamide1件: Tenofovir alafenamide; --2件: 2, 13
49 Atezolizumab
(Synonym: Tecentriq (TN))
1件: Atezolizumab (Synonym: Tecentriq)1件: Atezolizumab; 1件: CD274 💬2件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬1件: 85
50 Tezacaftor 1件: Tezacaftor5件: Kaftrio; Symdeko; Symkevi; TEZACAFTOR; Trikafta; 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
51 Tezepelumab 1件: Tezepelumab3件: AMG 157; MEDI9929; Tezepelumab; 1件: TSLP 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 98
52 Tesevatinib 1件: Tesevatinib1件: Tesevatinib; 5件: EGFR,
EPHB4,
ERBB2,
FLT4,
KDR 💬
53件: Adherens junction, Axon guidance, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction, VEGF signaling pathway 💬1件: 67