Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MAPK14 1件: Yersinia infection D09639 Losmapimod 2件: 113, 222
2 MAPK14 1件: Yersinia infection D10959 Neflamapimod 1件: 8
3 IL1B 1件: Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
4 IL1B 1件: Yersinia infection D06635 Rilonacept 4件: 51, 106, 107, 266
5 IL1B 1件: Yersinia infection D09315 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
6 IL1B 1件: Yersinia infection D09911 Gevokizumab 4件: 41, 50, 56, 269
7 IL6 1件: Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
8 IL6 1件: Yersinia infection D08976 Pomalidomide 5件: 28, 51, 85, 227, 331
9 IL6 1件: Yersinia infection D09669 Siltuximab 2件: 28, 331
10 IL6 1件: Yersinia infection D10080 Sirukumab 2件: 41, 46
11 IL6 1件: Yersinia infection D12487 Olokizumab 2件: 46, 96
12 IL10 1件: Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
13 ITGA4 1件: Yersinia infection D06590 Firategrast 1件: 13
14 ITGA4 1件: Yersinia infection D06886 Natalizumab 6件: 13, 15, 25, 46, 63, 96
15 ITGA4 1件: Yersinia infection D08083 Vedolizumab 3件: 94, 96, 97
16 ITGA4 1件: Yersinia infection D10540 Abrilumab 2件: 96, 97
17 LCK 1件: Yersinia infection D03658 Dasatinib 2件: 51, 85
18 LCK 1件: Yersinia infection D06414 Dasatinib 2件: 51, 85
19 NFKB1 1件: Yersinia infection D01146 Iguratimod 5件: 46, 51, 53, 271, 300
20 PIK3CA 1件: Yersinia infection D11011 Alpelisib 1件: 138
21 PIK3CA 1件: Yersinia infection D11158 Leniolisib 2件: 53, 65
22 PIK3CB 1件: Yersinia infection D11158 Leniolisib 2件: 53, 65
23 PIK3CD 1件: Yersinia infection D11158 Leniolisib 2件: 53, 65
24 PIK3CD 1件: Yersinia infection D11437 Parsaclisib 3件: 35, 53, 61
25 MAPK11 1件: Yersinia infection D09639 Losmapimod 2件: 113, 222
26 MAPK11 1件: Yersinia infection D10959 Neflamapimod 1件: 8
27 MAPK13 1件: Yersinia infection D09639 Losmapimod 2件: 113, 222
28 MAPK13 1件: Yersinia infection D10959 Neflamapimod 1件: 8
29 MAP2K1 1件: Yersinia infection D09666 Selumetinib 1件: 34
30 MAP2K1 1件: Yersinia infection D10175 Trametinib 4件: 2, 34, 279, 280
31 MAP2K1 1件: Yersinia infection D10405 Cobimetinib 1件: 280
32 MAP2K1 1件: Yersinia infection D10604 Binimetinib 1件: 34
33 MAP2K1 1件: Yersinia infection D11675 Mirdametinib 1件: 34
34 MAP2K2 1件: Yersinia infection D09666 Selumetinib 1件: 34
35 MAP2K2 1件: Yersinia infection D10175 Trametinib 4件: 2, 34, 279, 280
36 MAP2K2 1件: Yersinia infection D10405 Cobimetinib 1件: 280
37 MAP2K2 1件: Yersinia infection D10604 Binimetinib 1件: 34
38 MAP2K2 1件: Yersinia infection D11675 Mirdametinib 1件: 34
39 RELA 1件: Yersinia infection D12181 Edasalonexent 1件: 113
40 ROCK1 1件: Yersinia infection D07941 Fasudil 4件: 2, 5, 7, 51
41 MAPK12 1件: Yersinia infection D09639 Losmapimod 2件: 113, 222
42 MAPK12 1件: Yersinia infection D10959 Neflamapimod 1件: 8
43 CCL2 1件: Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
44 SRC 1件: Yersinia infection D03252 Bosutinib 2件: 2, 67
45 SRC 1件: Yersinia infection D03658 Dasatinib 2件: 51, 85
46 SRC 1件: Yersinia infection D06414 Dasatinib 2件: 51, 85
47 SRC 1件: Yersinia infection D09664 Saracatinib 3件: 6, 89, 272
48 TNF 1件: Yersinia infection D00742 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
49 TNF 1件: Yersinia infection D00754 Thalidomide 20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
50 TNF 1件: Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
51 TNF 1件: Yersinia infection D02597 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
52 TNF 1件: Yersinia infection D02598 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
53 TNF 1件: Yersinia infection D03441 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271
54 TNF 1件: Yersinia infection D04358 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271
55 TNF 1件: Yersinia infection D04687 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331
56 TNF 1件: Yersinia infection D05393 Pegsunercept 1件: 46
57 TNF 1件: Yersinia infection D08976 Pomalidomide 5件: 28, 51, 85, 227, 331
58 TNF 1件: Yersinia infection D09944 Ozoralizumab 1件: 46
59 CD4 1件: Yersinia infection D06356 Zanolimumab 1件: 46
60 ROCK2 1件: Yersinia infection D07941 Fasudil 4件: 2, 5, 7, 51
61 ROCK2 1件: Yersinia infection D11815 Belumosudil 2件: 51, 85