Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MAPK14 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
2 MAPK14 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
3 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D01977 Gefitinib 1件: 75
4 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D03455 Cetuximab 2件: 51, 86
5 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D07907 Erlotinib 1件: 94
6 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D08108 Lapatinib 3件: 34, 74, 75
7 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D08950 Neratinib 1件: 34
8 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D11251 Icotinib 1件: 34
9 EGFR 6件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer D11772 Tesevatinib 1件: 67
10 ERBB2 2件: Tight junction, Proteoglycans in cancer D08108 Lapatinib 3件: 34, 74, 75
11 ERBB2 2件: Tight junction, Proteoglycans in cancer D08950 Neratinib 1件: 34
12 ERBB2 2件: Tight junction, Proteoglycans in cancer D11772 Tesevatinib 1件: 67
13 ERBB4 1件: Proteoglycans in cancer D08950 Neratinib 1件: 34
14 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00105 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299
15 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00185 Estriol 2件: 13, 227
16 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00289 Danazol 5件: 60, 63, 64, 65, 285
17 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00554 Ethinylestradiol 4件: 13, 46, 49, 299
18 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D00575 Mestranol 2件: 46, 49
19 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D01161 Fulvestrant 2件: 49, 86
20 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D01413 Estradiol valerate 1件: 65
21 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D01986 Estriol 2件: 13, 227
22 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D02367 Desogestrel 1件: 230
23 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D07726 Clomifene 1件: 74
24 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D08409 Prasterone 6件: 49, 53, 83, 86, 96, 113
25 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D08465 Raloxifene 1件: 46
26 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D08559 Tamoxifen 3件: 2, 113, 227
27 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D11513 Estetrol 1件: 53
28 ESR1 2件: Thyroid hormone signaling pathway, Proteoglycans in cancer D11514 Estetrol 1件: 53
29 FGFR1 6件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Proteoglycans in cancer D10481 Nintedanib 5件: 51, 85, 89, 227, 228
30 FGFR1 6件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Proteoglycans in cancer D11589 Infigratinib 1件: 276
31 MTOR 7件: Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer D00753 Sirolimus 40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331
32 MTOR 7件: Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer D02714 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277
33 MTOR 7件: Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer D06068 Temsirolimus 1件: 13
34 IGF1R 5件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
35 IGF1R 5件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer D09680 Teprotumumab 1件: 51
36 IGF1R 5件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer D09925 Linsitinib 1件: 232
37 IL12B 7件: Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09214 Ustekinumab 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
38 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D03218 Axitinib 1件: 34
39 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D08524 Sorafenib 2件: 34, 86
40 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D08552 Sunitinib 2件: 28, 34
41 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D08881 Cediranib 1件: 34
42 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D10062 Cabozantinib 1件: 34
43 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D10481 Nintedanib 5件: 51, 85, 89, 227, 228
44 KDR 4件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Proteoglycans in cancer D11772 Tesevatinib 1件: 67
45 MET 5件: Ras signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer, Proteoglycans in cancer, Renal cell carcinoma D10062 Cabozantinib 1件: 34
46 PIK3CA 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Small cell lung cancer D11011 Alpelisib 1件: 138
47 PIK3CA 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
48 PIK3CB 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
49 PIK3CD 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
50 PIK3CD 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
51 PRKCB 13件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Salivary secretion, Spinocerebellar ataxia, Proteoglycans in cancer D11935 Enzastaurin 1件: 168
52 MAPK11 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
53 MAPK11 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
54 MAPK13 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
55 MAPK13 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
56 MAP2K1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
57 MAP2K1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
58 MAP2K1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
59 MAP2K1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
60 MAP2K1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D11675 Mirdametinib 1件: 34
61 MAP2K2 16件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
62 MAP2K2 16件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
63 MAP2K2 16件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
64 MAP2K2 16件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
65 MAP2K2 16件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D11675 Mirdametinib 1件: 34
66 RAF1 15件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma D08524 Sorafenib 2件: 34, 86
67 ROCK1 8件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Yersinia infection, Proteoglycans in cancer D07941 Fasudil 4件: 2, 5, 7, 51
68 MAPK12 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
69 MAPK12 19件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
70 SMO 1件: Proteoglycans in cancer D09992 Vismodegib 1件: 85
71 SMO 1件: Proteoglycans in cancer D10671 Taladegib 1件: 85
72 SRC 11件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03252 Bosutinib 2件: 2, 67
73 SRC 11件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03658 Dasatinib 2件: 51, 85
74 SRC 11件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D06414 Dasatinib 2件: 51, 85
75 SRC 11件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D09664 Saracatinib 3件: 6, 89, 272
76 BRAF 7件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D08524 Sorafenib 2件: 34, 86
77 BRAF 7件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Proteoglycans in cancer, Renal cell carcinoma, Thyroid cancer D10064 Dabrafenib 1件: 34
78 TGFB1 8件: TGF-beta signaling pathway, Th17 cell differentiation, Relaxin signaling pathway, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D09620 Fresolimumab 3件: 51, 85, 222
79 TGFB2 6件: TGF-beta signaling pathway, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D09620 Fresolimumab 3件: 51, 85, 222
80 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D00742 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
81 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D00754 Thalidomide 20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
82 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
83 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D02597 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
84 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D02598 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
85 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D03441 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271
86 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D04358 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271
87 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D04687 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331
88 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D05393 Pegsunercept 1件: 46
89 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D08976 Pomalidomide 5件: 28, 51, 85, 227, 331
90 TNF 17件: Viral protein interaction with cytokine and cytokine receptor, Sphingolipid signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer, Systemic lupus erythematosus, Rheumatoid arthritis D09944 Ozoralizumab 1件: 46
91 VEGFA 7件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D05697 Ranibizumab 4件: 34, 166, 227, 301
92 VEGFA 7件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D06409 Bevacizumab 6件: 13, 34, 85, 87, 227, 280
93 VEGFA 7件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Proteoglycans in cancer, Renal cell carcinoma, Rheumatoid arthritis D09574 Aflibercept 2件: 90, 166
94 ROCK2 9件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection, Proteoglycans in cancer D07941 Fasudil 4件: 2, 5, 7, 51
95 ROCK2 9件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection, Proteoglycans in cancer D11815 Belumosudil 2件: 51, 85