Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Human papillomavirus infection 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
2 Human papillomavirus infection 💬
1件: EGFR 💬 D03455 💬 Cetuximab 2件: 51, 86 💬
3 Human papillomavirus infection 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
4 Human papillomavirus infection 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
5 Human papillomavirus infection 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
6 Human papillomavirus infection 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
7 Human papillomavirus infection 💬
1件: EGFR 💬 D08950 💬 Neratinib 1件: 34 💬
8 Human papillomavirus infection 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
9 Human papillomavirus infection 💬
2件: HDAC1, HDAC2 💬 D06320 💬 Vorinostat 2件: 75, 96 💬
10 Human papillomavirus infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab 1件: 49 💬
11 Human papillomavirus infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab 1件: 49 💬
12 Human papillomavirus infection 💬
2件: IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab 3件: 46, 49, 53 💬
13 Human papillomavirus infection 💬
2件: IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa 6件: 13, 25, 26, 28, 56, 96 💬
14 Human papillomavirus infection 💬
2件: IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a 1件: 56 💬
15 Human papillomavirus infection 💬
2件: IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b 2件: 25, 34 💬
16 Human papillomavirus infection 💬
2件: IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a 4件: 13, 26, 96, 97 💬
17 Human papillomavirus infection 💬
2件: IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b 1件: 13 💬
18 Human papillomavirus infection 💬
2件: IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a 1件: 13 💬
19 Human papillomavirus infection 💬
1件: ITGA4 💬 D06590 💬 Firategrast 1件: 13 💬
20 Human papillomavirus infection 💬
1件: ITGA4 💬 D06886 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬
21 Human papillomavirus infection 💬
2件: ITGA4, ITGB7 💬 D10540 💬 Abrilumab 2件: 96, 97 💬
22 Human papillomavirus infection 💬
2件: ITGA4, ITGB7 💬 D08083 💬 Vedolizumab 3件: 94, 96, 97 💬
23 Human papillomavirus infection 💬
1件: ITGB7 💬 D09901 💬 Etrolizumab 2件: 96, 97 💬
24 Human papillomavirus infection 💬
1件: JAK1 💬 D11400 💬 Abrocitinib 1件: 84 💬
25 Human papillomavirus infection 💬
1件: JAK1 💬 D10308 💬 Baricitinib 13件:  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
26 Human papillomavirus infection 💬
1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
27 Human papillomavirus infection 💬
1件: JAK1 💬 D10944 💬 Itacitinib 4件: 46, 51, 97, 228 💬
28 Human papillomavirus infection 💬
1件: JAK1 💬 D10653 💬 Peficitinib 1件: 46 💬
29 Human papillomavirus infection 💬
1件: JAK1 💬 D09959 💬 Ruxolitinib 3件: 60, 65, 228 💬
30 Human papillomavirus infection 💬
1件: JAK1 💬 D10994 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
31 Human papillomavirus infection 💬
2件: JAK1, TYK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
32 Human papillomavirus infection 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
33 Human papillomavirus infection 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
34 Human papillomavirus infection 💬
2件: MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib 1件: 34 💬
35 Human papillomavirus infection 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
36 Human papillomavirus infection 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
37 Human papillomavirus infection 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
38 Human papillomavirus infection 💬
1件: MTOR 💬 D00753 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
39 Human papillomavirus infection 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 1件: 13 💬
40 Human papillomavirus infection 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬
41 Human papillomavirus infection 💬
1件: PDGFRB 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
42 Human papillomavirus infection 💬
1件: PDGFRB 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
43 Human papillomavirus infection 💬
1件: PDGFRB 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
44 Human papillomavirus infection 💬
1件: PDGFRB 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
45 Human papillomavirus infection 💬
1件: PDGFRB 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
46 Human papillomavirus infection 💬
2件: PDGFRB, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
47 Human papillomavirus infection 💬
1件: PIK3CA 💬 D11011 💬 Alpelisib 1件: 138 💬
48 Human papillomavirus infection 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
49 Human papillomavirus infection 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
50 Human papillomavirus infection 💬
1件: PSEN1 💬 D09010 💬 Tarenflurbil 1件: 13 💬
51 Human papillomavirus infection 💬
1件: PTGER4 💬 D00419 💬 Misoprostol 3件: 46, 70, 271 💬
52 Human papillomavirus infection 💬
1件: PTGS2 💬 D01545 💬 Aceclofenac 1件: 46 💬
53 Human papillomavirus infection 💬
1件: PTGS2 💬 D00217 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
54 Human papillomavirus infection 💬
1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
55 Human papillomavirus infection 💬
1件: PTGS2 💬 D00567 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
56 Human papillomavirus infection 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
57 Human papillomavirus infection 💬
1件: PTGS2 💬 D00130 💬 Diflunisal 1件: 28 💬
58 Human papillomavirus infection 💬
1件: PTGS2 💬 D00315 💬 Etodolac 1件: 46 💬
59 Human papillomavirus infection 💬
1件: PTGS2 💬 D03710 💬 Etoricoxib 2件: 46, 271 💬
60 Human papillomavirus infection 💬
1件: PTGS2 💬 D00330 💬 Flurbiprofen 3件: 13, 21, 46 💬
61 Human papillomavirus infection 💬
1件: PTGS2 💬 D00126 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
62 Human papillomavirus infection 💬
1件: PTGS2 💬 D00141 💬 Indomethacin 3件: 225, 271, 298 💬
63 Human papillomavirus infection 💬
1件: PTGS2 💬 D00132 💬 Ketoprofen 1件: 46 💬
64 Human papillomavirus infection 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
65 Human papillomavirus infection 💬
1件: PTGS2 💬 D08149 💬 Loxoprofen 2件: 46, 271 💬
66 Human papillomavirus infection 💬
1件: PTGS2 💬 D03714 💬 Lumiracoxib 1件: 46 💬
67 Human papillomavirus infection 💬
1件: PTGS2 💬 D00969 💬 Meloxicam 4件: 46, 49, 271, 296 💬
68 Human papillomavirus infection 💬
1件: PTGS2 💬 D00118 💬 Naproxen 4件: 13, 46, 107, 271 💬
69 Human papillomavirus infection 💬
1件: PTGS2 💬 D01049 💬 Nimesulide 1件: 46 💬
70 Human papillomavirus infection 💬
1件: PTGS2 💬 D03716 💬 Parecoxib 2件: 46, 271 💬
71 Human papillomavirus infection 💬
1件: PTGS2 💬 D00568 💬 Rofecoxib 1件: 46 💬
72 Human papillomavirus infection 💬
1件: PTGS2 💬 D00428 💬 Salsalate 1件:  5  💬
73 Human papillomavirus infection 💬
1件: PTGS2 💬 D00120 💬 Sulindac 1件: 206 💬
74 Human papillomavirus infection 💬
1件: PTGS2 💬 D01183 💬 Tolfenamic acid 1件:  5  💬
75 Human papillomavirus infection 💬
1件: PTGS2 💬 D02709 💬 Valdecoxib 1件: 46 💬
76 Human papillomavirus infection 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
77 Human papillomavirus infection 💬
1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
78 Human papillomavirus infection 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
79 Human papillomavirus infection 💬
1件: TNF 💬 D00742 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
80 Human papillomavirus infection 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
81 Human papillomavirus infection 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
82 Human papillomavirus infection 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
83 Human papillomavirus infection 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
84 Human papillomavirus infection 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
85 Human papillomavirus infection 💬
1件: TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
86 Human papillomavirus infection 💬
1件: TNF 💬 D08976 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬
87 Human papillomavirus infection 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
88 Human papillomavirus infection 💬
1件: TYK2 💬 D11817 💬 Deucravacitinib 3件: 49, 96, 97 💬
89 Human papillomavirus infection 💬
1件: VEGFA 💬 D09574 💬 Aflibercept 2件: 90, 166 💬
90 Human papillomavirus infection 💬
1件: VEGFA 💬 D06409 💬 Bevacizumab 6件: 13, 34, 85, 87, 227, 280 💬
91 Human papillomavirus infection 💬
1件: VEGFA 💬 D05697 💬 Ranibizumab 4件: 34, 166, 227, 301 💬
92 Human papillomavirus infection 💬
1件: VWF 💬 D11160 💬 Caplacizumab 1件: 64 💬