Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(2)-epigallocatechin-3-gallate (EGCG)[2] Epigallocatechin,
Epigallocatechin gallate		---[1] 8
220 mg BID of PF-02545920----[1] 8
320mg daily citalopram[1] Citalopram[1] D07704 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
45-Chloro-1,2-dihydro-N-ethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-3-quinolinecarboxamide sodium----[1] 8
5[123I]MNI-420----[2] 6, 8
6[18F]FPEB----[3] 6, 8, 206
7AAVrh10.CAG.hCYP46A1----[1] 8
8AB-1001 Gene Therapy----[1] 8
9ACR16----[1] 8
10ACR16 10 mg----[1] 8
11ACR16 22.5 mg----[1] 8
12ACR16 45 mg----[1] 8
13ACR16 hydrochloride, ASP2314 hydrochloride, FR310826----[1] 8
14ADENO-ASSOCIATED VIRAL VECTOR SEROTYPE RH10 CONTAINING THE HUMAN CHOLESTEROL 24-HYDROXYLASE GENE[1] Cholesterol[1] D00040 --[1] 8
15ADENO-ASSOCIATED VIRUS SEROTYPE 5 ENCODING A MICRORNA TARGETED TO HUMAN HUNTINGTIN GENE----[1] 8
16AFQ056----[3] 6, 8, 206
17Alprazolam[1] Alprazolam[1] D00225 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 8, 75
18AMANTADINE[1] Amantadine[1] D07441 [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127
19AMT----[4] 8, 46, 97, 321
20AMT-130[1] AMT-130---[1] 8
21Anti-Parkinson medication----[5] 5, 6, 7, 8, 17
22ANX005[1] ANX005---[3] 2, 8, 61
23Atomoxetine[1] Atomoxetine[1] D07473 [1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17
24Autologous Stem Cell----[1] 8
25Benerva----[1] 8
26Bevantolol[1] Bevantolol---[1] 8
27BEVANTOLOL HYDROCHLORIDE[1] Bevantolol---[1] 8
28BIOTIN[1] Biotin[1] D00029 --[5] 2, 8, 10, 13, 20
29Biotina[1] Biotin[1] D00029 --[2] 8, 13
30Blood sample----[20] 8, 13, 46, 49, 51, 53, 61, 66, 84, 88, 96, 97, 107, 127, 235, 274, 280, 288, 294, 299
31BN82451B----[1] 8
32BN8251B----[1] 8
33Branaplam[1] Branaplam[1] D12272 [1] SMN2 💬-[2] 3, 8
34Bupropion[1] Bupropion[1] D07591 [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
35BV-101----[1] 8
36Calvan (bevantolol hydrochloride)[1] Bevantolol---[1] 8
37Calvan® 100 mg----[1] 8
38Cannabidiol[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[18] 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
39CBD----[13] 2, 6, 8, 13, 36, 46, 51, 140, 144, 145, 156, 158, 206
40Cellavita HD Higher dose----[1] 8
41Cellavita HD Lower Dose----[1] 8
42Cellavita-HD----[1] 8
43Cholesterol[1] Cholesterol[1] D00040 --[6] 8, 19, 90, 160, 222, 310
44Citalopram[1] Citalopram[1] D07704 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
45CKD-504----[1] 8
46Coenzyme Q10[1] Ubidecarenone[1] D01065 --[11] 2, 5, 6, 8, 10, 18, 46, 57, 113, 214, 215
47CoQ10----[3] 5, 6, 8
48Creatine[1] Creatine---[11] 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201
49Creatine Monohydrate[1] Creatine---[4] 2, 8, 113, 156
50CYSTAGON[1] Cysteamine[1] D03634 --[3] 8, 19, 299
51Cysteamine[1] Cysteamine[1] D03634 --[4] 8, 19, 21, 299
52Cysteamine Bitartrate[1] Cysteamine[1] D03634 --[4] 8, 19, 21, 299
53Delta-9-tetrahydrocannabinol[1] Dronabinol[1] D00306 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[3] 8, 13, 36
54Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)[2] Cannabidiol,
Dronabinol		[2] D00306 ,
D10915 		[2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 8
55Deutetrabenazine[1] Deutetrabenazine[1] D10701 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
56Deutetrabenazine Oral Tablet [Austedo][1] Deutetrabenazine[1] D10701 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
57Dextromethorphan[1] Dextromethorphan[1] D03742 [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
58Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg)[2] Dextromethorphan,
Quinidine		[2] D03742 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[1] 8
59Digoxin[1] Digoxin[1] D00298 [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		[18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 8, 46, 210
60Dimebon[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
61Dimebon (latrepirdine)[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
62Dimebon + Dextromethorphan[2] Dextromethorphan,
Latrepirdine		[2] D03742 ,
D09917 		[7] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
63Dimebon + Ketoconazole[2] Ketoconazole,
Latrepirdine		[2] D00351 ,
D09917 		[7] ACHE,
CYP17A1,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[28] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Metabolic pathways, Neuroactive ligand-receptor interaction, Nicotine addiction, Ovarian steroidogenesis, Pathways of neurodegeneration - multiple diseases, Prion disease, Prolactin signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Steroid hormone biosynthesis, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
64Dimebon + Omeprazole[2] Latrepirdine,
Omeprazole		[2] D00455 ,
D09917 		[8] ACHE,
ATP4A,
ATP4B,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[26] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Dopaminergic synapse, Gastric acid secretion, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Metabolic pathways, Neuroactive ligand-receptor interaction, Nicotine addiction, Oxidative phosphorylation, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
65Dimebon alone[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
66Dimebon Dihydrochloride[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
67Dimebon IR[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
68Dimebon IR Tablet[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
69Dimebon MR1[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
70Dimebon MR2[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
71Dimebon MR3[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
72Dimebon MR4[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
73Dimebon Transdermal[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
74Divalproex----[1] 8
75DM----[2] 6, 8
76EGCG[1] Epigallocatechin gallate---[9] 6, 8, 13, 17, 28, 85, 113, 206, 299
77EPA----[6] 8, 46, 48, 49, 113, 301
78Epigallocatechin[1] Epigallocatechin---[5] 8, 13, 28, 85, 113
79Epigallocatechin-3-gallate[2] Epigallocatechin,
Epigallocatechin gallate		---[3] 8, 28, 85
80Ethyl Icosapent[1] Icosapent[1] D08061 --[1] 8
81Ethyl-EPA[1] Icosapent ethyl[1] D01892 --[1] 8
82Ethyl-EPA (Miraxion™)[1] Icosapent ethyl[1] D01892 --[1] 8
83Ethyl-Icosapent[1] Icosapent[1] D08061 --[1] 8
84Fenofibrate[1] Fenofibrate[1] D00565 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265
85Graft intracerebral of foetal neurons----[1] 8
86GSK356278----[1] 8
87Haloperidol[1] Haloperidol[1] D00136 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
88Haloperidol 2Mg Tab[1] Haloperidol[1] D00136 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
89High doses of Thiamine y Biotin[2] Biotin,
Thiamine		[2] D00029 ,
D08580 		--[1] 8
90HYPERIUM[1] Rilmenidine[1] D08482 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 8
91Icosapent[1] Icosapent[1] D08061 --[1] 8
92Idebenone[1] Idebenone[1] D01750 --[6] 6, 8, 13, 18, 113, 302
93Intra-striatal rAAV5-miHTT[1] AMT-130---[1] 8
94Intraparenchymal rAAV1 - (mi)RNA HTT----[1] 8
95ISIS 443139 10 mg----[1] 8
96ISIS 443139 120 mg----[1] 8
97ISIS 443139 30 mg----[1] 8
98ISIS 443139 60 mg----[1] 8
99ISIS 443139 90 mg----[1] 8
100Ketoconazole[1] Ketoconazole[1] D00351 [1] CYP17A1 💬[6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[3] 8, 13, 75
101LAQUINIMOD[1] Laquinimod---[4] 8, 13, 49, 96
102Laquinimod capsules 0.5 mg[1] Laquinimod---[2] 8, 96
103Latrepirdine[1] Latrepirdine[1] D09917 [6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
104LAX-101[1] LAX-101---[1] 8
105Lithium[1] Lithium citrate[1] D04749 --[5] 2, 5, 6, 7, 8
106LMI070----[2] 3, 8
107LPM3770164 sustained release tablet[1] Manganese citrate---[1] 8
108LPM3770164 sustained release tablet simulant[1] Manganese citrate---[1] 8
109Melatonin[1] Melatonin[1] D08170 [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202
110Memantine[1] Memantine[1] D08174 [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206
111Metformin[1] Metformin[1] D04966 [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
112Minocycline[1] Minocycline[1] D05045 --[13] 2, 6, 8, 13, 46, 85, 90, 94, 162, 201, 206, 280, 299
113Moderate doses of Thiamine y Biotin[2] Biotin,
Thiamine		[2] D00029 ,
D08580 		--[1] 8
114Mutation in the gene----[1] 8
115N.a.----[10] 3, 6, 8, 13, 46, 96, 97, 240, 256, 271
116Neflamapimod[1] Neflamapimod[1] D10959 [4] MAPK11,
MAPK12,
MAPK13,
MAPK14 💬		[62] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[1] 8
117Nilotinib[1] Nilotinib[1] D08953 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬		[33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86
118Nilotinib 150 MG[1] Nilotinib[1] D08953 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬		[33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[1] 8
119Non invasive prenatal diagnosis----[3] 8, 113, 206
120OLANZAPINE[1] Olanzapine[1] D00454 [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
121Omeprazole[1] Omeprazole[1] D00455 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
122OMS643762----[1] 8
123OSU6162 similar to (-)-OSU 6162----[2] 6, 8
124PBF-999----[1] 8
125PBF-999 / 160 mg----[1] 8
126PBF-999 / 320 mg----[1] 8
127PBT2----[1] 8
128PF-02545920----[1] 8
129PHENYLBUTYRATE[1] Phenylbutyric acid---[12] 2, 3, 6, 8, 15, 93, 94, 244, 251, 297, 299, 338
130PL101----[1] 8
131Pridiopidine----[1] 8
132Pridopidina----[1] 8
133Pridopidine[1] Pridopidine[1] D09953 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8
134Pridopidine (90 mg)[1] Pridopidine[1] D09953 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
135PRIDOPIDINE HYDROCHLORIDE[1] Pridopidine[1] D09953 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
136PTC518----[1] 8
137PTC518 tablet 20 mg----[1] 8
138PTC518 tablet 5 mg----[1] 8
139Quinidine[1] Quinidine[1] D08458 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13
140RAAV5-miHTT[1] AMT-130---[1] 8
141Ramelteon[1] Ramelteon[1] D02689 [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46
142Release[1] Manganese citrate---[12] 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299
143Resveratrol[1] Resveratrol---[6] 2, 8, 18, 89, 97, 113
144RG6042, formerly ISIS 443139, IONIS-HTTRx----[1] 8
145Rilmenidine[1] Rilmenidine[1] D08482 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 8
146RILUZOLE[1] Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
147Risperidone[1] Risperidone[1] D00426 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206
148Risperidone 1Mg Tab[1] Risperidone[1] D00426 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 8
149Ro 723-4292/F02----[1] 8
150RO7234292----[1] 8
151RO7234292 (RG6042)----[1] 8
152Rolipram[1] Rolipram[1] D01783 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 8, 13
153RP 103----[2] 8, 19
154RP103----[2] 8, 19
155SAGE-718----[2] 6, 8
156SBT-020----[1] 8
157SD-809----[1] 8
158Selisistat[1] Selisistat---[1] 8
159SEN0014196----[1] 8
160SEN0014196 (High Dose)----[1] 8
161SEN0014196 (Low Dose)----[1] 8
162Sodium phenylbutyrate[1] Phenylbutyric acid---[4] 2, 3, 8, 251
163SOM3355----[1] 8
164SOM3355 (bevantolol hydrochloride)[1] Bevantolol---[1] 8
165SOM3355 100mg BID----[1] 8
166SOM3355 200mg BID----[1] 8
167SOM3355 capsules----[1] 8
168SRX246----[1] 8
169SS-20----[1] 8
170Tetrabenazine[1] Tetrabenazine[1] D08575 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
171Tetrabenazine withdrawal[1] Tetrabenazine[1] D08575 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
172Tetrahydrocannabinol[1] Dronabinol[1] D00306 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[4] 8, 13, 36, 298
173THC----[5] 8, 13, 36, 46, 96
174Thiamine[1] Thiamine[1] D08580 --[3] 8, 93, 265
175Tiapridal----[1] 8
176Tominersen----[1] 8
177Tominersen 100 mg----[1] 8
178Tominersen 60 mg----[1] 8
179Triheptanoin[1] Triheptanoin[1] D11465 --[10] 2, 8, 65, 149, 156, 248, 256, 257, 317, 324
180Triheptanoin 1g/kg/day[1] Triheptanoin[1] D11465 --[1] 8
181Triheptanoin oil[1] Triheptanoin[1] D11465 --[1] 8
182TV-5600----[3] 8, 13, 96
183TV-7820----[1] 8
184Ubiquinol[1] Ubiquinol---[3] 6, 8, 17
185Ursodiol[1] Ursodeoxycholic acid[1] D00734 [1] NR1H4 💬[1] Bile secretion 💬[6] 8, 20, 93, 97, 234, 299
186UX007----[4] 8, 248, 256, 257
187Valbenazine[1] Valbenazine[1] D10675 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
188Vitamin B7[1] Biotin[1] D00029 --[1] 8
189VX-745----[1] 8
190VX15/2503----[2] 8, 13
191Warfarin[1] Warfarin[1] D08682 [2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91
192WVE-003----[1] 8
193WVE-120101----[1] 8
194WVE-120102----[1] 8
195Xenazine[1] Tetrabenazine[1] D08575 [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
196Zoloft 50Mg Tablet----[1] 8