Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ACE [1] Renin-angiotensin system D00251 Captopril [8] 6, 17, 46, 86, 96, 97, 107, 271
2 ACE [1] Renin-angiotensin system D00362 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222
3 ACE [1] Renin-angiotensin system D00421 Ramipril [7] 46, 49, 66, 67, 113, 218, 257
4 ACE [1] Renin-angiotensin system D01069 Cilazapril [1] 66
5 ACE [1] Renin-angiotensin system D03752 Quinapril [1] 19
6 ACE [1] Renin-angiotensin system D03753 Perindopril [4] 58, 113, 167, 222
7 ACE [1] Renin-angiotensin system D07499 Benazepril [4] 49, 57, 218, 224
8 ACE [1] Renin-angiotensin system D07699 Cilazapril [1] 66
9 ACE [1] Renin-angiotensin system D07892 Enalapril [6] 19, 46, 66, 113, 210, 222
10 ACE [1] Renin-angiotensin system D08068 Imidapril [1] 67
11 ACE [1] Renin-angiotensin system D08131 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222
12 ACE [1] Renin-angiotensin system D08225 Moexipril [1] 93
13 AGTR1 [2] Vascular smooth muscle contraction, Renin-angiotensin system D00150 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
14 AGTR1 [2] Vascular smooth muscle contraction, Renin-angiotensin system D00400 Valsartan [7] 57, 58, 66, 75, 218, 222, 224
15 AGTR1 [2] Vascular smooth muscle contraction, Renin-angiotensin system D00522 Candesartan [2] 58, 67
16 AGTR1 [2] Vascular smooth muscle contraction, Renin-angiotensin system D00523 Irbesartan [4] 66, 167, 168, 222
17 AGTR1 [2] Vascular smooth muscle contraction, Renin-angiotensin system D00626 Candesartan cilexetil [1] 67
18 AGTR1 [2] Vascular smooth muscle contraction, Renin-angiotensin system D00627 Telmisartan [2] 66, 67
19 AGTR1 [2] Vascular smooth muscle contraction, Renin-angiotensin system D02014 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
20 AGTR1 [2] Vascular smooth muscle contraction, Renin-angiotensin system D08146 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
21 AGTR1 [2] Vascular smooth muscle contraction, Renin-angiotensin system D11776 Sparsentan [3] 66, 218, 222
22 AGTR2 [1] Renin-angiotensin system D00150 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
23 AGTR2 [1] Renin-angiotensin system D02014 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
24 ANPEP [1] Renin-angiotensin system D00087 Ubenimex [1] 86
25 MME [1] Renin-angiotensin system D10225 Sacubitril [2] 58, 222
26 REN [1] Renin-angiotensin system D03208 Aliskiren [3] 66, 167, 222