Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 COMT [2] Steroid hormone biosynthesis, Tyrosine metabolism D00781 Entacapone [2] 6, 17
2 COMT [2] Steroid hormone biosynthesis, Tyrosine metabolism D00786 Tolcapone [3] 6, 28, 127
3 COMT [2] Steroid hormone biosynthesis, Tyrosine metabolism D10825 Opicapone [1] 6
4 CYP11A1 [1] Steroid hormone biosynthesis D10950 Levoketoconazole [1] 75
5 CYP11B1 [1] Steroid hormone biosynthesis D00410 Metyrapone [1] 75
6 CYP11B1 [1] Steroid hormone biosynthesis D10950 Levoketoconazole [1] 75
7 CYP11B2 [1] Steroid hormone biosynthesis D11061 Osilodrostat [1] 75
8 CYP17A1 [1] Steroid hormone biosynthesis D00351 Ketoconazole [3] 8, 13, 75
9 CYP17A1 [1] Steroid hormone biosynthesis D10950 Levoketoconazole [1] 75
10 CYP19A1 [1] Steroid hormone biosynthesis D00960 Anastrozole [3] 78, 86, 193
11 CYP19A1 [1] Steroid hormone biosynthesis D00964 Letrozole [2] 81, 89
12 SRD5A1 [1] Steroid hormone biosynthesis D03820 Dutasteride [2] 1, 2
13 SRD5A2 [1] Steroid hormone biosynthesis D00321 Finasteride [1] 6
14 SRD5A2 [1] Steroid hormone biosynthesis D03820 Dutasteride [2] 1, 2