Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
2 AGE-RAGE signaling pathway in diabetic complications 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
3 Aldosterone-regulated sodium reabsorption 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
4 Alzheimer disease 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
5 Amoebiasis 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
6 AMPK signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
7 Apoptosis 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
8 Autophagy - animal 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
9 Axon guidance 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
10 B cell receptor signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
11 Bacterial invasion of epithelial cells 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
12 Breast cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
13 C-type lectin receptor signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
14 cAMP signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
15 Carbohydrate digestion and absorption 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
16 Cellular senescence 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
17 Central carbon metabolism in cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
18 Chagas disease 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
19 Chemical carcinogenesis - reactive oxygen species 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
20 Chemical carcinogenesis - receptor activation 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
21 Chemokine signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
22 Choline metabolism in cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
23 Cholinergic synapse 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
24 Chronic myeloid leukemia 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
25 Colorectal cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
26 Coronavirus disease - COVID-19 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
27 Diabetic cardiomyopathy 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
28 EGFR tyrosine kinase inhibitor resistance 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
29 Endocrine resistance 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
30 Endometrial cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
31 Epstein-Barr virus infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
32 ErbB signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
33 Estrogen signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
34 Fc epsilon RI signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
35 Fc gamma R-mediated phagocytosis 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
36 Fluid shear stress and atherosclerosis 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
37 Focal adhesion 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
38 FoxO signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
39 Gastric cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
40 Glioma 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
41 GnRH secretion 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
42 Growth hormone synthesis, secretion and action 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
43 Hepatitis B 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
44 Hepatitis C 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
45 Hepatocellular carcinoma 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
46 Herpes simplex virus 1 infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
47 HIF-1 signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
48 Human cytomegalovirus infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
49 Human immunodeficiency virus 1 infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
50 Human papillomavirus infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
51 Human T-cell leukemia virus 1 infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
52 Inflammatory mediator regulation of TRP channels 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
53 Influenza A 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
54 Inositol phosphate metabolism 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
55 Insulin resistance 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
56 Insulin signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
57 JAK-STAT signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
58 Kaposi sarcoma-associated herpesvirus infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
59 Leukocyte transendothelial migration 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
60 Lipid and atherosclerosis 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
61 Longevity regulating pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
62 Longevity regulating pathway - multiple species 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
63 Measles 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
64 Melanoma 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
65 Metabolic pathways 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
66 MicroRNAs in cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
67 mTOR signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
68 Natural killer cell mediated cytotoxicity 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
69 Neurotrophin signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
70 Neutrophil extracellular trap formation 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
71 Non-alcoholic fatty liver disease 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
72 Non-small cell lung cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
73 Osteoclast differentiation 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
74 Pancreatic cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
75 Pathways in cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
76 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
77 Phosphatidylinositol signaling system 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
78 Phospholipase D signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
79 PI3K-Akt signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
80 Platelet activation 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
81 Platinum drug resistance 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
82 Prion disease 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
83 Progesterone-mediated oocyte maturation 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
84 Prolactin signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
85 Prostate cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
86 Proteoglycans in cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
87 Rap1 signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
88 Ras signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
89 Regulation of actin cytoskeleton 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
90 Regulation of lipolysis in adipocytes 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
91 Relaxin signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
92 Renal cell carcinoma 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
93 Salmonella infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
94 Shigellosis 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
95 Signaling pathways regulating pluripotency of stem cells 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
96 Small cell lung cancer 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
97 Sphingolipid signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
98 Spinocerebellar ataxia 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
99 T cell receptor signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
100 Thyroid hormone signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
101 TNF signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
102 Toll-like receptor signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
103 Type II diabetes mellitus 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
104 VEGF signaling pathway 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
105 Viral carcinogenesis 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
106 Yersinia infection 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬