Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ABAT [1] ABAT 💬 |
D00535 D00535 💬 |
Vigabatrin | 145 [2] 145, 158 💬 |
2 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ABAT [3] ABAT, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
3 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
4 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
5 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
6 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
7 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
8 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
9 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
10 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
11 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
12 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
13 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [20] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
14 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 [2] 13, 206 💬 |
15 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D08861 D08861 💬 |
Arbaclofen Placarbil | 013 [1] 13 💬 |
16 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
17 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D12240 D12240 💬 |
Valiloxybate | 006 [1] 6 💬 |
18 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [1] GABRA1 💬 |
D00548 D00548 💬 |
Etomidate | 006 [1] 6 💬 |
19 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00225 D00225 💬 |
Alprazolam | 008 [2] 8 , 75 💬 |
20 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D11149 D11149 💬 |
Brexanolone | 205 [1] 205 💬 |
21 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
22 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00280 D00280 💬 |
Clonazepam | 006 [1] 6 💬 |
23 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D07784 D07784 💬 |
Delorazepam | 006 [3] 6 , 46, 97 💬 |
24 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
25 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D02624 D02624 💬 |
Eszopiclone | 006 [3] 6 , 13, 46 💬 |
26 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 [5] 6 , 13, 17, 18, 206 💬 |
27 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 [2] 201, 206 💬 |
28 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 [4] 145, 152, 158, 206 💬 |
29 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00365 D00365 💬 |
Lorazepam | 036 [1] 36 💬 |
30 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
31 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
32 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D08690 D08690 💬 |
Zolpidem | 005 [3] 5 , 6 , 46 💬 |
33 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01372 D01372 💬 |
Zopiclone | 006 [1] 6 💬 |
34 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
35 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
SLC6A1 [1] SLC6A1 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
36 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
37 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
38 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
39 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
40 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GAA [1] GAA 💬 |
D03207 D03207 💬 |
Alglucosidase alfa | 256 [1] 256 💬 |
41 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GAA [1] GAA 💬 |
D11744 D11744 💬 |
Avalglucosidase alfa | 256 [1] 256 💬 |
42 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GAA [1] GAA 💬 |
D11798 D11798 💬 |
Cipaglucosidase alfa | 256 [1] 256 💬 |
43 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GAA [1] GAA 💬 |
D09605 D09605 💬 |
Duvoglustat | 256 [1] 256 💬 |
44 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GAA [3] GAA, GANC, MGAM 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
45 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GLA [1] GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 [1] 19 💬 |
46 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GLA [1] GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 [1] 19 💬 |
47 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
48 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
49 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 [4] 58, 67, 86, 113 💬 |
50 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00255 D00255 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 |
51 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07660 D07660 💬 |
Celiprolol | 168 [1] 168 💬 |
52 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
53 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 |
54 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
55 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
56 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
57 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
58 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
59 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00432 D00432 💬 |
Nadolol | 006 [1] 6 💬 |
60 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
61 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [2] 22, 296 💬 |
62 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
63 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
64 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00378 D00378 💬 |
Timolol | 157 [2] 157, 227 💬 |
65 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D08600 D08600 💬 |
Timolol | 157 [2] 157, 227 💬 |
66 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D11431 D11431 💬 |
Tavapadon | 006 [1] 6 💬 |
67 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
68 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
69 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
70 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D01044 D01044 💬 |
Flupentixol | 097 [1] 97 💬 |
71 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D11839 D11839 💬 |
Foslevodopa | 006 [1] 6 💬 |
72 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 |
73 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D08339 D08339 💬 |
Pergolide | 006 [1] 6 💬 |
74 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
75 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07593 D07593 💬 |
Buspirone | 006 [2] 6 , 51 💬 |
76 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
77 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
78 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
79 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00136 D00136 💬 |
Haloperidol | 008 [1] 8 💬 |
80 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
81 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07309 D07309 💬 |
Melperone | 006 [1] 6 💬 |
82 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00726 D00726 💬 |
Metoclopramide | 046 [2] 46, 51 💬 |
83 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09397 D09397 💬 |
Pardoprunox | 006 [1] 6 💬 |
84 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
85 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07305 D07305 💬 |
Piribedil | 006 [1] 6 💬 |
86 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 |
87 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
88 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
89 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05768 D05768 💬 |
Rotigotine | 006 [1] 6 💬 |
90 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 006 [2] 6 , 70 💬 |
91 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
92 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08590 D08590 💬 |
Tiapride | 008 [1] 8 💬 |
93 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01448 D01448 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
94 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08636 D08636 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
95 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [2] DRD2, HTR2A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 |
96 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [2] DRD2, HTR2A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 [1] 21 💬 |
97 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [2] DRD2, HTR2A 💬 |
D08456 D08456 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
98 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [2] DRD2, HTR2A 💬 |
D00426 D00426 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 |
99 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
100 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 |
D02666 D02666 💬 |
Iloperidone | 006 [1] 6 💬 |
101 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
102 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
103 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
104 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
105 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
106 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
107 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
108 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
109 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
110 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
111 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
HTR2A [1] HTR2A 💬 |
D00274 D00274 💬 |
Cisapride | 013 [1] 13 💬 |
112 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
HTR2A [1] HTR2A 💬 |
D02092 D02092 💬 |
Cisapride | 013 [1] 13 💬 |
113 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
HTR2A [1] HTR2A 💬 |
D09645 D09645 💬 |
Nelotanserin | 006 [1] 6 💬 |
114 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D08626 D08626 💬 |
Trazodone | 002 [1] 2 💬 |
115 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
HTR2A [2] HTR2A, HTR2C 💬 |
D00283 D00283 💬 |
Clozapine | 006 [1] 6 💬 |
116 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
HTR2A [2] HTR2A, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 |
117 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
HTR2C [1] HTR2C 💬 |
D02578 D02578 💬 |
Agomelatine | 006 [1] 6 💬 |
118 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
119 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
120 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
121 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
122 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
123 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
124 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
125 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
126 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
127 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRB [2] PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
128 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRB [2] PDGFRB, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
129 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PDGFRB [2] PDGFRB, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
130 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
131 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
132 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
133 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D11595 D11595 💬 |
Belantamab mafodotin | 028 [1] 28 💬 |
134 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D09587 D09587 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 |
135 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
136 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00491 D00491 💬 |
Paclitaxel | 046 [2] 46, 85 💬 |
137 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 [2] 34, 65 💬 |
138 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 [4] 26, 34, 65, 331 💬 |
139 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
140 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
141 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D08903 D08903 💬 |
Dexlansoprazole | 098 [1] 98 💬 |
142 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
143 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬 |
144 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
145 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D05353 D05353 💬 |
Pantoprazole | 013 [2] 13, 65 💬 |
146 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D08463 D08463 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
147 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D11784 D11784 💬 |
Vonoprazan | 063 [2] 63, 98 💬 |
148 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 |
149 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CA2 [1] CA2 💬 |
D00518 D00518 💬 |
Diclofenamide | 114 [1] 114 💬 |
150 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CA2 [1] CA2 💬 |
D07871 D07871 💬 |
Dorzolamide | 090 [1] 90 💬 |
151 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CA2 [1] CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
152 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CCKBR [1] CCKBR 💬 |
D01818 D01818 💬 |
Proglumide | 298 [1] 298 💬 |
153 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 [1] 299 💬 |
154 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 [1] 299 💬 |
155 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 [1] 299 💬 |
156 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR [1] CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 [1] 299 💬 |
157 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR [1] CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 [1] 299 💬 |
158 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 [1] 299 💬 |
159 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 [2] 2 , 299 💬 |
160 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 [1] 156 💬 |
161 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D07667 D07667 💬 |
Cevimeline | 053 [1] 53 💬 |
162 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
163 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D03654 D03654 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
164 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 [1] 6 💬 |
165 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
166 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
167 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
168 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
169 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D08522 D08522 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
170 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
171 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
172 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00397 D00397 💬 |
Tropicamide | 006 [1] 6 💬 |
173 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00295 D00295 💬 |
Cimetidine | 002 [2] 2 , 254 💬 |
174 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [6] 6 , 46, 61, 86, 98, 107 💬 |
175 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00422 D00422 💬 |
Ranitidine | 013 [2] 13, 65 💬 |
176 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
KCNQ1 [1] KCNQ1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
177 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
178 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
179 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
SSTR2 [1] SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬 |
180 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
SSTR2 [1] SSTR2 💬 |
D10147 D10147 💬 |
Pasireotide | 067 [3] 67, 74, 75 💬 |
181 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
SSTR2 [1] SSTR2 💬 |
D07431 D07431 💬 |
Somatostatin | 067 [2] 67, 78 💬 |
182 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
183 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
184 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
185 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
186 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
187 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
188 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
189 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
190 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
191 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
192 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
FGF23 [1] FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 [1] 238 💬 |
193 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
194 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
195 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 |
196 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
197 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
198 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
199 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
200 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
201 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
202 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
203 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
204 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [1] 13 💬 |
205 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
206 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
207 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
208 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RARB [1] RARB 💬 |
D04162 D04162 💬 |
Fenretinide | 299 [1] 299 💬 |
209 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RARB [1] RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
210 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RARB [1] RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬 |
211 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RARB [1] RARB 💬 |
D06543 D06543 💬 |
Vitamin A | 013 [3] 13, 53, 90 💬 |
212 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RARB [4] RARB, RXRA, RXRB, RXRG 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
213 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RARB [4] RARB, RXRA, RXRB, RXRG 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
214 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 [2] 13, 75 💬 |
215 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 |
216 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
217 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
218 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
CDK4 [2] CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
219 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
220 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
221 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
222 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
223 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
224 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
225 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
226 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
227 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
228 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
229 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
230 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
231 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
232 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
233 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
234 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
235 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
236 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [1] 13 💬 |
237 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
238 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
239 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
240 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
241 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PDGFRB [1] PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
242 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PDGFRB [1] PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
243 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
244 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
245 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
246 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
247 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
CPT1A [3] CPT1A, CPT1B, CPT1C 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
248 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
249 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
250 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
251 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
252 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 |
253 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
254 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
255 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
256 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
257 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
258 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
259 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 |
260 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPARA [1] PPARA 💬 |
D11208 D11208 💬 |
Elafibranor | 093 [2] 93, 94 💬 |
261 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPARA [1] PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬 |
262 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPARA [1] PPARA 💬 |
D10711 D10711 💬 |
Pemafibrate | 093 [1] 93 💬 |
263 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
264 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
265 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
266 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
267 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 049 [2] 49, 222 💬 |
268 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
269 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
270 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
271 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
272 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
273 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
274 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
275 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
276 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
277 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
278 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
279 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [11] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
280 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
281 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
282 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
283 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
284 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
285 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
286 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
287 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
288 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
289 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
290 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
KCNJ3 [1] KCNJ3 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
291 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
292 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
293 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
294 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
295 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 049 [2] 49, 222 💬 |
296 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
297 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
ANPEP [1] ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 [1] 86 💬 |
298 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
ODC1 [1] ODC1 💬 |
D07883 D07883 💬 |
Eflornithine | 065 [1] 65 💬 |
299 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
RRM1 [1] RRM1 💬 |
D01370 D01370 💬 |
Cladribine | 011 [3] 11, 13, 94 💬 |
300 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
RRM1 [1] RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 [5] 19, 20, 60, 234, 326 💬 |
301 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
RRM1 [1] RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
302 | Glutathione metabolism 💬 Related to 4 target genes, 6 drugs (DrugBank) and 25 diseases in DDrare |
RRM2 [1] RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
303 | Glycerolipid metabolism 💬 Related to 1 target gene, 2 drugs (DrugBank) and 1 disease in DDrare |
GLA [1] GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 [1] 19 💬 |
304 | Glycerolipid metabolism 💬 Related to 1 target gene, 2 drugs (DrugBank) and 1 disease in DDrare |
GLA [1] GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 [1] 19 💬 |
305 | Glycerophospholipid metabolism 💬 Related to 1 target gene, 5 drugs (DrugBank) and 11 diseases in DDrare |
ACHE [1] ACHE 💬 |
D07869 D07869 💬 |
Donepezil | 005 [9] 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
306 | Glycerophospholipid metabolism 💬 Related to 1 target gene, 5 drugs (DrugBank) and 11 diseases in DDrare |
ACHE [1] ACHE 💬 |
D04292 D04292 💬 |
Galantamine | 006 [2] 6 , 127 💬 |
307 | Glycerophospholipid metabolism 💬 Related to 1 target gene, 5 drugs (DrugBank) and 11 diseases in DDrare |
ACHE [1] ACHE 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
308 | Glycerophospholipid metabolism 💬 Related to 1 target gene, 5 drugs (DrugBank) and 11 diseases in DDrare |
ACHE [1] ACHE 💬 |
D03822 D03822 💬 |
Rivastigmine | 005 [3] 5 , 6 , 13 💬 |
309 | Glycerophospholipid metabolism 💬 Related to 1 target gene, 5 drugs (DrugBank) and 11 diseases in DDrare |
ACHE [1] ACHE 💬 |
D08555 D08555 💬 |
Tacrine | 046 [2] 46, 271 💬 |
310 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
ALAS1 [1] ALAS1 💬 |
D11702 D11702 💬 |
Givosiran | 254 [1] 254 💬 |
311 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
ALAS1 [2] ALAS1, ALAS2 💬 |
D10003 D10003 💬 |
Hemin | 254 [1] 254 💬 |
312 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
AOC3 [1] AOC3 💬 |
D08044 D08044 💬 |
Hydralazine | 067 [1] 67 💬 |
313 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [1] MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 [1] 6 💬 |
314 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 [1] 6 💬 |
315 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 [1] 6 💬 |
316 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D05458 D05458 💬 |
Phentermine | 097 [1] 97 💬 |
317 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 |
318 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 |
319 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 [2] 6 , 17 💬 |
320 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOB [1] MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 [1] 6 💬 |
321 | Glycolysis / Gluconeogenesis 💬 Related to 3 target genes, 1 drug (DrugBank) and 1 disease in DDrare |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
D00707 D00707 💬 |
Fomepizole | 301 [1] 301 💬 |
322 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
ARSB [1] ARSB 💬 |
D06565 D06565 💬 |
Galsulfase | 019 [1] 19 💬 |
323 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
GALNS [1] GALNS 💬 |
D10333 D10333 💬 |
Elosulfase alfa | 019 [1] 19 💬 |
324 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
GUSB [1] GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 [1] 19 💬 |
325 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
IDS [1] IDS 💬 |
D04499 D04499 💬 |
Idursulfase | 019 [1] 19 💬 |
326 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
IDS [1] IDS 💬 |
D11025 D11025 💬 |
Idursulfase beta | 019 [1] 19 💬 |
327 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
IDS [1] IDS 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 [1] 19 💬 |
328 | Glycosaminoglycan degradation 💬 Related to 5 target genes, 7 drugs (DrugBank) and 2 diseases in DDrare |
IDUA [1] IDUA 💬 |
D04670 D04670 💬 |
Laronidase | 019 [2] 19, 256 💬 |
329 | Glycosphingolipid biosynthesis - globo and isoglobo series 💬 Related to 1 target gene, 2 drugs (DrugBank) and 1 disease in DDrare |
GLA [1] GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 [1] 19 💬 |
330 | Glycosphingolipid biosynthesis - globo and isoglobo series 💬 Related to 1 target gene, 2 drugs (DrugBank) and 1 disease in DDrare |
GLA [1] GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 [1] 19 💬 |
331 | Glyoxylate and dicarboxylate metabolism 💬 Related to 1 target gene, 1 drug (DrugBank) and 1 disease in DDrare |
HAO1 [1] HAO1 💬 |
D11925 D11925 💬 |
Lumasiran | 234 [1] 234 💬 |
332 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
333 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
334 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
335 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
336 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
337 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
338 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
339 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
340 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
341 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
342 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
343 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 149 [1] 149 💬 |
344 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
345 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
346 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
347 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D11513 D11513 💬 |
Estetrol | 053 [1] 53 💬 |
348 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D11514 D11514 💬 |
Estetrol | 053 [1] 53 💬 |
349 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
350 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 [1] 65 💬 |
351 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D00185 D00185 💬 |
Estriol | 013 [2] 13, 227 💬 |
352 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D01986 D01986 💬 |
Estriol | 013 [2] 13, 227 💬 |
353 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
354 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D00575 D00575 💬 |
Mestranol | 046 [2] 46, 49 💬 |
355 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
356 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D08465 D08465 💬 |
Raloxifene | 046 [1] 46 💬 |
357 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
ESR2 [1] ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [3] 2 , 113, 227 💬 |
358 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 [2] 13, 206 💬 |
359 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D08861 D08861 💬 |
Arbaclofen Placarbil | 013 [1] 13 💬 |
360 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
361 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D12240 D12240 💬 |
Valiloxybate | 006 [1] 6 💬 |
362 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
KCNJ11 [1] KCNJ11 💬 |
D00294 D00294 💬 |
Diazoxide | 013 [2] 13, 193 💬 |
363 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
KCNJ11 [1] KCNJ11 💬 |
D00418 D00418 💬 |
Minoxidil | 179 [1] 179 💬 |
364 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
KCNJ11 [1] KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 [4] 6 , 21, 46, 299 💬 |
365 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
KCNJ11 [3] KCNJ11, KCNJ3, KCNJ5 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
366 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
367 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
368 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
369 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
370 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
371 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
372 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
373 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
374 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
375 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
376 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
377 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
378 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
379 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
380 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
381 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
382 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
383 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
384 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
385 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
386 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
387 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
388 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
389 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
390 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
391 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
392 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
393 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
394 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
GNRHR [1] GNRHR 💬 |
D07665 D07665 💬 |
Cetrorelix | 046 [1] 46 💬 |
395 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
GNRHR [1] GNRHR 💬 |
D08027 D08027 💬 |
Gonadorelin | 076 [1] 76 💬 |
396 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
GNRHR [1] GNRHR 💬 |
D04405 D04405 💬 |
Goserelin | 001 [1] 1 💬 |
397 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
GNRHR [1] GNRHR 💬 |
D02369 D02369 💬 |
Histrelin | 076 [1] 76 💬 |
398 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
GNRHR [1] GNRHR 💬 |
D06247 D06247 💬 |
Triptorelin | 049 [2] 49, 76 💬 |
399 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
400 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
401 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
402 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
403 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
404 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
405 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
406 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
407 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
PRKCD [1] PRKCD 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
408 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
409 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
410 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
411 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
412 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
413 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
414 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
415 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [3] 49, 65, 107 💬 |
416 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
417 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
418 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
419 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
420 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
421 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
422 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL6 [1] IL6 💬 |
D12487 D12487 💬 |
Olokizumab | 046 [2] 46, 96 💬 |
423 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
424 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
425 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 |
426 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
427 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
428 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
429 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
430 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
431 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
432 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
433 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
434 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
435 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
436 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
437 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
438 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
439 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
440 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
441 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
442 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
443 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
444 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
445 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
446 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHR [1] GHR 💬 |
D11486 D11486 💬 |
Lonapegsomatropin | 078 [1] 78 💬 |
447 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHR [1] GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
448 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHR [1] GHR 💬 |
D05394 D05394 💬 |
Pegvisomant | 078 [2] 78, 265 💬 |
449 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHR [1] GHR 💬 |
D11194 D11194 💬 |
Somapacitan | 078 [2] 78, 195 💬 |
450 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHR [1] GHR 💬 |
D11193 D11193 💬 |
Somavaratan | 078 [1] 78 💬 |
451 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHRHR [1] GHRHR 💬 |
D08523 D08523 💬 |
Somatorelin | 013 [2] 13, 78 💬 |
452 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHRHR [1] GHRHR 💬 |
D06655 D06655 💬 |
Tesamorelin | 078 [2] 78, 265 💬 |
453 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
GHSR [1] GHSR 💬 |
D10563 D10563 💬 |
Macimorelin | 078 [1] 78 💬 |
454 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
455 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
456 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 |
457 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
458 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
459 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
460 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
461 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
462 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
463 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
464 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
465 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
466 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
467 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [1] 13 💬 |
468 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
469 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
470 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
471 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
472 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
473 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
SSTR1 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 |
D10147 D10147 💬 |
Pasireotide | 067 [3] 67, 74, 75 💬 |
474 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
SSTR1 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 |
D07431 D07431 💬 |
Somatostatin | 067 [2] 67, 78 💬 |
475 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
SSTR2 [1] SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬 |