Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
3 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
4 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
5 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
6 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
7 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
8 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
9 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
10 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
11 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
12 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
13 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
14 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
15 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
16 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
17 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
18 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
19 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
20 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
21 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
22 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
23 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
24 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
25 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
26 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
27 | Carbohydrate digestion and absorption 💬 Related to 14 target genes, 19 drugs (DrugBank) and 30 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
28 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
29 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
30 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
31 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
32 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
33 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
34 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
35 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
36 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
37 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
38 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
39 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
40 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
41 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
42 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
43 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
44 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
45 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
46 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
47 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
48 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
49 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
50 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
51 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
52 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
53 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
54 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
55 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
REN [1] REN 💬 |
D03208 D03208 💬 |
Aliskiren | 066 [3] 66, 167, 222 💬 |
56 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
57 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
58 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
59 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
60 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
61 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
62 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
63 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
64 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
65 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
66 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
67 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
68 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
69 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
70 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
71 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
72 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
73 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
74 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
75 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
76 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
77 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
78 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
79 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
80 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
81 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
82 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
83 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
84 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
85 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
86 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
87 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
88 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
89 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
90 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
91 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
92 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
93 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
94 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
95 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
96 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
REN [1] REN 💬 |
D03208 D03208 💬 |
Aliskiren | 066 [3] 66, 167, 222 💬 |
97 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
98 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
99 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
100 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
REN [1] REN 💬 |
D03208 D03208 💬 |
Aliskiren | 066 [3] 66, 167, 222 💬 |
101 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
102 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
103 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
104 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
105 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
106 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
107 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
108 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
109 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
110 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
111 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
112 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |