Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
2 Alcoholism 💬
 [2] DRD1, DRD2 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
3 Amphetamine addiction 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
4 Amphetamine addiction 💬
 [1] DRD1 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
5 Calcium signaling pathway 💬
 [2] DRD1, DRD5 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
6 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
7 Cocaine addiction 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
8 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
9 Dopaminergic synapse 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
10 Dopaminergic synapse 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
11 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D04282 💬 Gaboxadol [2] 201, 206 💬
12 Gap junction 💬
 [2] DRD1, DRD2 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
13 Metabolic pathways 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
14 Morphine addiction 💬
 [1] DRD1 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
15 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D04282 💬 Gaboxadol [2] 201, 206 💬
16 Neuroactive ligand-receptor interaction 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
17 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D04282 💬 Gaboxadol [2] 201, 206 💬
18 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D04282 💬 Gaboxadol [2] 201, 206 💬
19 Parkinson disease 💬
 [2] DRD1, DRD2 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
20 Phenylalanine metabolism 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
21 Rap1 signaling pathway 💬
 [1] DRD2 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
22 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D04282 💬 Gaboxadol [2] 201, 206 💬
23 Serotonergic synapse 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
24 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 D04282 💬 Gaboxadol [2] 201, 206 💬
25 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D04282 💬 Gaboxadol [2] 201, 206 💬
26 Tryptophan metabolism 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
27 Tyrosine metabolism 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬

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