Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | Alanine, aspartate and glutamate metabolism 💬 Related to 5 target genes, 3 drugs (DrugBank) and 19 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
| 2 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
PDE2A [1] PDE2A 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 3 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 4 | Arginine biosynthesis 💬 Related to 1 target gene, 1 drug (DrugBank) and 3 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
| 5 | Biosynthesis of amino acids 💬 Related to 2 target genes, 2 drugs (DrugBank) and 4 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
| 6 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 7 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 8 | Carbon metabolism 💬 Related to 2 target genes, 2 drugs (DrugBank) and 4 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
| 9 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 10 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 11 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 12 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 13 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 14 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
| 15 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 16 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 17 | Nitrogen metabolism 💬 Related to 14 target genes, 5 drugs (DrugBank) and 18 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
| 18 | Olfactory transduction 💬 Related to 4 target genes, 5 drugs (DrugBank) and 13 diseases in DDrare |
PDE1A [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 19 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 20 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 21 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 22 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 23 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PDE1A [5] PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 24 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |