Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adherens junction 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
2	Alcoholism 💬	[2] DRD1, DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
3	Alcoholism 💬	[1] DRD2 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
4	Alcoholism 💬	[1] DRD2 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
5	Alcoholism 💬	[1] DRD2 💬	D08489 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
6	Amphetamine addiction 💬	[1] DRD1 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
7	Bladder cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
8	Breast cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
9	Breast cancer 💬	[2] ESR1, ESR2 💬	D07726 💬	Clomifene	[1] 74 💬
10	Calcium signaling pathway 💬	[2] DRD1, DRD5 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
11	Calcium signaling pathway 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
12	cAMP signaling pathway 💬	[3] DRD1, DRD2, DRD5 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
13	cAMP signaling pathway 💬	[1] DRD2 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
14	cAMP signaling pathway 💬	[1] DRD2 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
15	cAMP signaling pathway 💬	[1] DRD2 💬	D08489 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
16	cAMP signaling pathway 💬	[3] SSTR1, SSTR2, SSTR5 💬	D10147 💬	Pasireotide	[3] 67, 74, 75 💬
17	Central carbon metabolism in cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
18	Chemical carcinogenesis - reactive oxygen species 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
19	Chemical carcinogenesis - receptor activation 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
20	Chemical carcinogenesis - receptor activation 💬	[2] ESR1, ESR2 💬	D07726 💬	Clomifene	[1] 74 💬
21	Choline metabolism in cancer 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
22	Cocaine addiction 💬	[2] DRD1, DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
23	Cocaine addiction 💬	[1] DRD2 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
24	Cocaine addiction 💬	[1] DRD2 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
25	Cocaine addiction 💬	[1] DRD2 💬	D08489 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
26	Colorectal cancer 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
27	Coronavirus disease - COVID-19 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
28	Cushing syndrome 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
29	Cytokine-cytokine receptor interaction 💬	[1] PRL 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
30	Cytokine-cytokine receptor interaction 💬	[1] PRL 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
31	Dopaminergic synapse 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
32	Dopaminergic synapse 💬	[1] DRD2 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
33	Dopaminergic synapse 💬	[1] DRD2 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
34	Dopaminergic synapse 💬	[3] DRD2, DRD3, DRD4 💬	D08489 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
35	EGFR tyrosine kinase inhibitor resistance 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
36	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D07726 💬	Clomifene	[1] 74 💬
37	Endocrine resistance 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
38	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D07726 💬	Clomifene	[1] 74 💬
39	Endocytosis 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
40	Endometrial cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
41	Epithelial cell signaling in Helicobacter pylori infection 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
42	ErbB signaling pathway 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
43	Estrogen signaling pathway 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
44	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D07726 💬	Clomifene	[1] 74 💬
45	Focal adhesion 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
46	FoxO signaling pathway 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
47	Gap junction 💬	[2] DRD1, DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
48	Gap junction 💬	[1] DRD2 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
49	Gap junction 💬	[1] DRD2 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
50	Gap junction 💬	[1] DRD2 💬	D08489 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
51	Gap junction 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
52	Gastric acid secretion 💬	[1] SSTR2 💬	D10147 💬	Pasireotide	[3] 67, 74, 75 💬
53	Gastric cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
54	Glioma 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
55	GnRH secretion 💬	[1] ESR2 💬	D07726 💬	Clomifene	[1] 74 💬
56	GnRH signaling pathway 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
57	Growth hormone synthesis, secretion and action 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬	D10147 💬	Pasireotide	[3] 67, 74, 75 💬
58	Hepatitis C 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
59	Hepatocellular carcinoma 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
60	HIF-1 signaling pathway 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
61	Human cytomegalovirus infection 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
62	Human papillomavirus infection 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
63	JAK-STAT signaling pathway 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
64	JAK-STAT signaling pathway 💬	[1] PRL 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
65	JAK-STAT signaling pathway 💬	[1] PRL 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
66	MAPK signaling pathway 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
67	Melanoma 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
68	MicroRNAs in cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
69	Morphine addiction 💬	[1] DRD1 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
70	Neuroactive ligand-receptor interaction 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
71	Neuroactive ligand-receptor interaction 💬	[3] DRD2, DRD3, DRD4 💬	D08489 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
72	Neuroactive ligand-receptor interaction 💬	[2] DRD2, PRL 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
73	Neuroactive ligand-receptor interaction 💬	[2] DRD2, PRL 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
74	Neuroactive ligand-receptor interaction 💬	[4] SSTR1, SSTR2, SSTR3, SSTR5 💬	D10147 💬	Pasireotide	[3] 67, 74, 75 💬
75	Non-small cell lung cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
76	Oxytocin signaling pathway 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
77	Pancreatic cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
78	Parathyroid hormone synthesis, secretion and action 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
79	Parkinson disease 💬	[2] DRD1, DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
80	Parkinson disease 💬	[1] DRD2 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
81	Parkinson disease 💬	[1] DRD2 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
82	Parkinson disease 💬	[1] DRD2 💬	D08489 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
83	Pathways in cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
84	Pathways in cancer 💬	[2] ESR1, ESR2 💬	D07726 💬	Clomifene	[1] 74 💬
85	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
86	Phospholipase D signaling pathway 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
87	PI3K-Akt signaling pathway 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
88	PI3K-Akt signaling pathway 💬	[1] PRL 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
89	PI3K-Akt signaling pathway 💬	[1] PRL 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
90	Platinum drug resistance 💬	[1] ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
91	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D07726 💬	Clomifene	[1] 74 💬
92	Prolactin signaling pathway 💬	[1] PRL 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
93	Prolactin signaling pathway 💬	[1] PRL 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
94	Prostate cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
95	Proteoglycans in cancer 💬	[2] EGFR, ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
96	Proteoglycans in cancer 💬	[1] ESR1 💬	D07726 💬	Clomifene	[1] 74 💬
97	Rap1 signaling pathway 💬	[1] DRD2 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
98	Rap1 signaling pathway 💬	[1] DRD2 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
99	Rap1 signaling pathway 💬	[1] DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
100	Rap1 signaling pathway 💬	[1] DRD2 💬	D08489 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
101	Rap1 signaling pathway 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
102	Ras signaling pathway 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
103	Regulation of actin cytoskeleton 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
104	Relaxin signaling pathway 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
105	Shigellosis 💬	[1] EGFR 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
106	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D07726 💬	Clomifene	[1] 74 💬
107	Tight junction 💬	[1] ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬