Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Breast cancer 💬
[2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
2 Breast cancer 💬
[1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
3 Breast cancer 💬
[1] PGR 💬 D00066 💬 Progesterone [2] 76, 299 💬
4 Chemical carcinogenesis - receptor activation 💬
[1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬
5 Chemical carcinogenesis - receptor activation 💬
[2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
6 Chemical carcinogenesis - receptor activation 💬
[1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
7 Chemical carcinogenesis - receptor activation 💬
[1] PGR 💬 D00066 💬 Progesterone [2] 76, 299 💬
8 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
9 Endocrine resistance 💬
[2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
10 Estrogen signaling pathway 💬
[2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
11 Estrogen signaling pathway 💬
[1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
12 Estrogen signaling pathway 💬
[1] PGR 💬 D00066 💬 Progesterone [2] 76, 299 💬
13 GnRH secretion 💬
[1] ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
14 GnRH signaling pathway 💬
[1] GNRHR 💬 D08027 💬 Gonadorelin [1] 76 💬
15 GnRH signaling pathway 💬
[1] GNRHR 💬 D02369 💬 Histrelin [1] 76 💬
16 GnRH signaling pathway 💬
[1] GNRHR 💬 D06247 💬 Triptorelin [2] 49, 76 💬
17 Neuroactive ligand-receptor interaction 💬
[1] GNRHR 💬 D08027 💬 Gonadorelin [1] 76 💬
18 Neuroactive ligand-receptor interaction 💬
[1] GNRHR 💬 D02369 💬 Histrelin [1] 76 💬
19 Neuroactive ligand-receptor interaction 💬
[1] GNRHR 💬 D06247 💬 Triptorelin [2] 49, 76 💬
20 Oocyte meiosis 💬
[1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬
21 Oocyte meiosis 💬
[1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
22 Oocyte meiosis 💬
[1] PGR 💬 D00066 💬 Progesterone [2] 76, 299 💬
23 Pathways in cancer 💬
[1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬
24 Pathways in cancer 💬
[2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
25 Progesterone-mediated oocyte maturation 💬
[1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
26 Progesterone-mediated oocyte maturation 💬
[1] PGR 💬 D00066 💬 Progesterone [2] 76, 299 💬
27 Prolactin signaling pathway 💬
[2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
28 Prostate cancer 💬
[1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬
29 Proteoglycans in cancer 💬
[1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
30 Thyroid hormone signaling pathway 💬
[1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬